{"id":"dexycu-intracameral-dexamethasone","safety":{"commonSideEffects":[{"rate":null,"effect":"Increased intraocular pressure"},{"rate":null,"effect":"Corneal edema"},{"rate":null,"effect":"Anterior chamber inflammation"},{"rate":null,"effect":"Eye discomfort"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Dexamethasone is a potent glucocorticoid that suppresses inflammatory cytokines and immune cell infiltration. When delivered directly into the eye via intracameral injection at the time of cataract surgery, it provides sustained local anti-inflammatory effects to reduce postoperative inflammation, pain, and corneal edema without systemic exposure.","oneSentence":"Dexycu is an intracameral corticosteroid that reduces inflammation in the anterior chamber of the eye following cataract surgery.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:32:40.242Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Postoperative inflammation and pain following cataract surgery"}]},"trialDetails":[{"nctId":"NCT06951087","phase":"PHASE3","title":"Intravitreal and Intracameral DEX in NPDR","status":"ENROLLING_BY_INVITATION","sponsor":"Affiliated Hospital of Nantong University","startDate":"2022-01-31","conditions":"Non-Proliferative Diabetic Retinopathy","enrollment":80},{"nctId":"NCT04781335","phase":"PHASE4","title":"\"A Prospective Study of the Efficacy of Intracameral Dexamethasone (Dexycu™) Compared to Standard of Care Treatment for Post-Cataract Surgical Pain and Anterior Chamber Inflammation\"","status":"COMPLETED","sponsor":"The Eye Institute of West Florida","startDate":"2020-02-20","conditions":"Cataract","enrollment":25},{"nctId":"NCT04184999","phase":"PHASE4","title":"Effect of Intraoperative Dexamethasone on Post-op Dry Eye","status":"COMPLETED","sponsor":"SR Cornea Consultants","startDate":"2019-08-10","conditions":"Dry Eye Syndromes","enrollment":40},{"nctId":"NCT03634852","phase":"PHASE4","title":"A Two Chemoprophylaxis Approaches After Phacoemulsification Surgery","status":"COMPLETED","sponsor":"Suzan A Rattan","startDate":"2016-10-01","conditions":"Endophthalmitis Postoperative","enrollment":1000},{"nctId":"NCT04273282","phase":"PHASE4","title":"A Prospective Clinical Study Evaluating Dexycu vs Prednisolone Acetate 1%","status":"COMPLETED","sponsor":"Research Insight LLC","startDate":"2019-12-16","conditions":"Cataract","enrollment":31},{"nctId":"NCT04205916","phase":"PHASE4","title":"A Trial Evaluating Patient Preference of Dropless vs Drops Post Cataract Surgery","status":"RECRUITING","sponsor":"Ophthalmic Consultants of Long Island","startDate":"2019-11-04","conditions":"Patient Preference","enrollment":50},{"nctId":"NCT03361709","phase":"PHASE4","title":"Effect of Intracameral Dexamethasone After Phacoemulsification in Diabetics on Corneal Endothelial Cell Density","status":"WITHDRAWN","sponsor":"Cairo University","startDate":"2018-01-01","conditions":"Diabetes Mellitus, Corneal Endothelial Cell Loss, Dexamethasone Adverse Reaction","enrollment":""},{"nctId":"NCT02547623","phase":"PHASE3","title":"Study to Evaluate the Safety for the Treatment of Inflammation Associated With Cataract Surgery","status":"COMPLETED","sponsor":"ICON Bioscience Inc","startDate":"2015-11-06","conditions":"Cataract","enrollment":194}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":17,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Moxifloxacin 0.5%","Prolensa"],"phase":"marketed","status":"active","brandName":"Dexycu intracameral dexamethasone","genericName":"Dexycu intracameral dexamethasone","companyName":"Research Insight LLC","companyId":"research-insight-llc","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Dexycu is an intracameral corticosteroid that reduces inflammation in the anterior chamber of the eye following cataract surgery. Used for Postoperative inflammation and pain following cataract surgery.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}