{"id":"dextrofemine","rwe":[{"pmid":"2313067","year":"1990","title":"[Doppler umbilical artery velocimetry during labor in normal pregnancies].","finding":"","journal":"Journal de gynecologie, obstetrique et biologie de la reproduction","studyType":"Clinical Study"}],"tags":[{"label":"dextrofemine","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":["dextrofemine","dextrofemine fumarate"],"offLabel":[],"synonyms":["dextrofemine","dextrofemine fumarate"],"timeline":[],"approvals":[],"ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"dextrofemine","explanation":"Imagine your brain is a city with many different streets and intersections. DEXTROFEMINE helps to increase the traffic flow of certain important chemicals, called neurotransmitters, that allow different parts of the brain to communicate with each other. This can help to improve focus, attention, and energy, but it can also have negative effects if not used carefully.","oneSentence":"DEXTROFEMINE is a stimulant that works by increasing the levels of certain neurotransmitters in the brain.","technicalDetail":"DEXTROFEMINE is a central nervous system stimulant that acts as a norepinephrine-dopamine reuptake inhibitor, increasing the levels of these neurotransmitters in the synaptic cleft and enhancing their activity."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/840","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=DEXTROFEMINE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T10:37:46.690907","biosimilars":[],"competitors":[],"genericName":"dextrofemine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"WVB6I50566","CHEBI":"CHEBI:135109","INN_ID":"2067","UMLSCUI":"C2699618","ChEMBL_ID":"CHEMBL2106250","PUBCHEM_CID":"71879"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":1,"therapeuticAreas":["Neuroscience"],"biosimilarFilings":[],"recentPublications":[{"date":"1990","pmid":"2313067","title":"[Doppler umbilical artery velocimetry during labor in normal pregnancies].","journal":"Journal de gynecologie, obstetrique et biologie de la reproduction"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","brandName":"DEXTROFEMINE","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"DEXTROFEMINE is a small molecule drug belonging to the dextrofemine class, but its original developer and current owner are unknown. Its target and approved indications are also not specified. The commercial status of DEXTROFEMINE is unclear, with unknown patent status and generic manufacturers. Key safety considerations are not available due to the lack of FDA approval and available information. Further research is necessary to understand the pharmacology and clinical use of DEXTROFEMINE.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}