{"id":"dexamethasone-late","safety":{"commonSideEffects":[{"rate":null,"effect":"Hyperglycemia"},{"rate":null,"effect":"Hypertension"},{"rate":null,"effect":"Increased infection risk"},{"rate":null,"effect":"Gastric perforation"},{"rate":null,"effect":"Growth suppression"}]},"_chembl":{"chemblId":"CHEMBL1697787","moleculeType":"Small molecule","molecularWeight":"528.57"},"_fixedAt":"2026-03-30T13:29:33.809103","_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Dexamethasone exerts its anti-inflammatory effects by translocating to the nucleus and modulating gene expression of pro-inflammatory cytokines, adhesion molecules, and other immune mediators. In the context of late administration in neonates, it is used to reduce chronic lung inflammation and improve respiratory outcomes in infants at risk of bronchopulmonary dysplasia. The drug's immunosuppressive properties help mitigate ventilator-induced lung injury and inflammatory cascades in premature infants.","oneSentence":"Dexamethasone is a synthetic glucocorticoid that suppresses inflammation and immune responses by binding to glucocorticoid receptors.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:45:46.326Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention or treatment of chronic lung disease (bronchopulmonary dysplasia) in premature neonates requiring mechanical ventilation"}]},"_fixedFields":["pubmed(1852)"],"trialDetails":[{"nctId":"NCT06966700","phase":"PHASE3","title":"A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)","status":"RECRUITING","sponsor":"Merck Sharp & Dohme LLC","startDate":"2025-06-30","conditions":"Breast Neoplasms, Triple Negative Breast Neoplasms, HR Low-Positive/HER2-Negative Breast Neoplasms","enrollment":2400},{"nctId":"NCT06235567","phase":"PHASE1, PHASE2","title":"Dextenza Versus Topical Steroid Eye Drops for Postoperative Management Following Corneal Crosslinking","status":"ENROLLING_BY_INVITATION","sponsor":"Maanasa Indaram, MD","startDate":"2025-04-11","conditions":"Keratoconus","enrollment":20},{"nctId":"NCT06577025","phase":"PHASE2","title":"A Study of Different Sequences of Cilta-cel, Talquetamab in Combination With Daratumumab and Teclistamab in Combination With Daratumumab Following Induction With Daratumumab, Bortezomib, Lenalidomide and Dexamethasone in Participants With Standard-risk Newly Diagnosed Multiple Myeloma","status":"ACTIVE_NOT_RECRUITING","sponsor":"Janssen Research & Development, LLC","startDate":"2024-08-20","conditions":"Multiple Myeloma","enrollment":43},{"nctId":"NCT07149857","phase":"PHASE2","title":"A Study to Evaluate Efficacy and Safety of Ciltacabtagene Autoleucel","status":"RECRUITING","sponsor":"Janssen Research & Development, LLC","startDate":"2025-10-03","conditions":"Multiple Myeloma","enrollment":60},{"nctId":"NCT05581030","phase":"PHASE1","title":"CalPeg for Newly Diagnosed Acute Lymphoblastic Leukemia (ALL)","status":"RECRUITING","sponsor":"H. Lee Moffitt Cancer Center and Research Institute","startDate":"2023-05-01","conditions":"Acute Lymphoblastic Leukemia","enrollment":7},{"nctId":"NCT06863259","phase":"PHASE1","title":"Study of Inotuzumab Ozogamicin, Venetoclax, and Dexamethasone for Relapsed B-cell ALL","status":"RECRUITING","sponsor":"Children's Hospital Medical Center, Cincinnati","startDate":"2025-05-21","conditions":"B-cell Acute Lymphoblastic Leukemia","enrollment":28},{"nctId":"NCT06212336","phase":"PHASE2, PHASE3","title":"ISTH/ANRS 0409s INTEGRATE Lassa Fever Study","status":"RECRUITING","sponsor":"Irrua Specialist Teaching Hospital","startDate":"2025-05-02","conditions":"Lassa Fever","enrollment":1755},{"nctId":"NCT05954780","phase":"","title":"Selinexor (Nexpovio®) (SVd) in Patients With Relapsed or Refractory Multiple Myeloma","status":"ACTIVE_NOT_RECRUITING","sponsor":"iOMEDICO AG","startDate":"2023-06-28","conditions":"Multiple Myeloma","enrollment":75},{"nctId":"NCT05192889","phase":"PHASE1, PHASE2","title":"Trial Treating Relapsed Acute Lymphoblastic Leukemia With Venetoclax and Navitoclax","status":"ACTIVE_NOT_RECRUITING","sponsor":"St. Jude Children's Research Hospital","startDate":"2022-08-25","conditions":"Refractory Acute Lymphoblastic Leukemia, Relapsed Acute Lymphoblastic Leukemia","enrollment":35},{"nctId":"NCT06022939","phase":"PHASE3","title":"Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis","status":"RECRUITING","sponsor":"SWOG Cancer Research Network","startDate":"2024-07-01","conditions":"AL Amyloidosis","enrollment":338},{"nctId":"NCT03004287","phase":"PHASE2","title":"2015-12: A Study Exploring the Use of Early and Late Consolidation/Maintenance Therapy","status":"ACTIVE_NOT_RECRUITING","sponsor":"University of Arkansas","startDate":"2017-07-01","conditions":"Multiple Myeloma","enrollment":50},{"nctId":"NCT03567473","phase":"PHASE3","title":"Bronchiolitis in Infants Placebo Versus Epinephrine and Dexamethasone Study","status":"COMPLETED","sponsor":"Children's Hospital of Eastern Ontario","startDate":"2018-12-13","conditions":"Bronchiolitis","enrollment":864},{"nctId":"NCT06307444","phase":"NA","title":"Ultrasound-Guided Erectro Spinae Plane Block Versus Stellate Ganglion Block for Patients With Upper Limb Acute Herpes Zoster Pain.","status":"COMPLETED","sponsor":"Tanta University","startDate":"2024-03-20","conditions":"Acute Herpes Zoster Pain Managment","enrollment":93},{"nctId":"NCT05753046","phase":"PHASE4","title":"Laparoscopic TAP Block During Robotic Assisted Laparoscopic Radical Prostatectomy for Improvement in Postoperative Pain","status":"ENROLLING_BY_INVITATION","sponsor":"Corewell Health East","startDate":"2024-02-19","conditions":"Prostate Cancer","enrollment":94},{"nctId":"NCT05403359","phase":"","title":"StEroids in hospitaLized patiEnts With Covid-19 in The Netherlands.","status":"COMPLETED","sponsor":"Henrik Endeman","startDate":"2022-06-01","conditions":"COVID-19","enrollment":2465},{"nctId":"NCT06402279","phase":"","title":"Hemoperfusion Efferon СT for the Extremely Severe Form of COVID-19","status":"COMPLETED","sponsor":"Efferon JSC","startDate":"2020-10-01","conditions":"COVID-19","enrollment":130},{"nctId":"NCT05038878","phase":"PHASE4","title":"An Oral GnRH Antagonist to Treat Mild Autonomous Cortisol Excess (MACE) Due to Adrenal Adenomas in Postmenopausal Women","status":"TERMINATED","sponsor":"Icahn School of Medicine at Mount Sinai","startDate":"2021-07-06","conditions":"Mild Autonomous Cortisol Excess","enrollment":4},{"nctId":"NCT06764238","phase":"PHASE2, PHASE3","title":"Newly-diagnosed Intermediate/High Risk Pediatric B-cell ALL Protocol","status":"RECRUITING","sponsor":"Institute of Hematology & Blood Diseases Hospital, China","startDate":"2025-01-03","conditions":"Acute Lymphoblastic Leukemia ALL, Childhood Leukemia, Acute Lymphoblastic, B Cell Acute Lymphoblastic Leukemia (B-ALL)","enrollment":1800},{"nctId":"NCT05895838","phase":"PHASE3","title":"The Danish Out-of-Hospital Cardiac Arrest Study","status":"RECRUITING","sponsor":"Christian Hassager","startDate":"2023-06-16","conditions":"Out-Of-Hospital Cardiac Arrest, Post-Cardiac Arrest Syndrome","enrollment":1000},{"nctId":"NCT06788158","phase":"PHASE1","title":"Clinical Effects of Incobotulinum Toxin vs Corticosteroid in Plantar Fascitis","status":"ACTIVE_NOT_RECRUITING","sponsor":"Instituto Mexicano del Seguro Social","startDate":"2024-09-01","conditions":"Plantar Fasciitis of Both Feet, Pain, Function","enrollment":20},{"nctId":"NCT06256679","phase":"","title":"RADIOFREQUENCY TREATMENT OF CHRONIC PELVIC PAIN MANAGEMENT IN INTERSTITIAL CYSTITIS","status":"COMPLETED","sponsor":"Turkish League Against Rheumatism","startDate":"2022-12-27","conditions":"Interstitial Cystitis, Chronic","enrollment":34},{"nctId":"NCT05841121","phase":"PHASE1","title":"Antenatal Dexamethasone for Late Preterm Deliveries","status":"UNKNOWN","sponsor":"Chulalongkorn University","startDate":"2023-08-25","conditions":"Respiratory Distress of Newborn, Preterm Birth","enrollment":294},{"nctId":"NCT04381936","phase":"PHASE3","title":"Randomised Evaluation of COVID-19 Therapy","status":"RECRUITING","sponsor":"University of Oxford","startDate":"2020-03-19","conditions":"Severe Acute Respiratory Syndrome","enrollment":70000},{"nctId":"NCT03922412","phase":"NA","title":"Plantar Compartment Block Versus Sciatic Block in Hallux Valgus Ambulatory Surgery","status":"COMPLETED","sponsor":"University Hospital, Montpellier","startDate":"2019-06-24","conditions":"Anesthesia","enrollment":60},{"nctId":"NCT04528329","phase":"PHASE4","title":"Anosmia and / or Ageusia and Early Corticosteroid Use","status":"UNKNOWN","sponsor":"ClinAmygate","startDate":"2021-03-30","conditions":"Covid19, Anosmia","enrollment":300},{"nctId":"NCT04530409","phase":"PHASE4","title":"Timing of Corticosteroids in COVID-19, II. Post COVID-19 Follow-up","status":"UNKNOWN","sponsor":"ClinAmygate","startDate":"2021-03-20","conditions":"Covid19, Corticosteroids","enrollment":752},{"nctId":"NCT06006091","phase":"NA","title":"The Effectiveness of the Letrozole-induced Endometrial Preparation Protocol in Frozen-thawed Embryo Transfer (FET)","status":"RECRUITING","sponsor":"International Peace Maternity and Child Health Hospital","startDate":"2023-08-01","conditions":"Letrozole, Infertility, Female","enrollment":858},{"nctId":"NCT01936532","phase":"PHASE2","title":"Safety and Efficacy Study of a Triplet Combination of MLN9708, Lenalidomide and Dexamethasone in the Initial Management of Multiple Myeloma (IFM2013-06)","status":"COMPLETED","sponsor":"Nantes University Hospital","startDate":"2014-11-12","conditions":"Newly Diagnosed Multiple Myeloma","enrollment":42},{"nctId":"NCT04201444","phase":"NA","title":"Hair Cortisol and Cushing's Disease","status":"COMPLETED","sponsor":"University Hospital, Bordeaux","startDate":"2021-03-10","conditions":"Cushing Disease","enrollment":51},{"nctId":"NCT02623426","phase":"PHASE3","title":"Macular Edema Ranibizumab v. Intravitreal Anti-inflammatory Therapy Trial","status":"COMPLETED","sponsor":"JHSPH Center for Clinical Trials","startDate":"2017-03-09","conditions":"Uveitis, Macular Edema","enrollment":194},{"nctId":"NCT02186834","phase":"PHASE1, PHASE2","title":"Selinexor (KPT-330) and Liposomal Doxorubicin For Relapsed and Refractory Multiple Myeloma","status":"COMPLETED","sponsor":"H. Lee Moffitt Cancer Center and Research Institute","startDate":"2014-09-23","conditions":"Multiple Myeloma","enrollment":28},{"nctId":"NCT03200808","phase":"PHASE1","title":"Methylene Blue Injection for Nonneoplastic Epithelial Disorders of Vulva","status":"COMPLETED","sponsor":"Maternal and Child Health Hospital of Hubei Province","startDate":"2013-10-01","conditions":"Nonneoplastic Epithelial Disorders of Vulva","enrollment":118},{"nctId":"NCT01782820","phase":"","title":"Influence of a Single Dose Dexamethasone on the Time Course of Neuromuscular Blockade of Rocuronium","status":"COMPLETED","sponsor":"Kreiskrankenhaus Dormagen","startDate":"2011-12","conditions":"Neuromuscular Block, Dexamethasone, Neuromuscular Block, Recovery","enrollment":108},{"nctId":"NCT05362253","phase":"NA","title":"Micro-Conjunctival Autografting Combined With Amniotic Membrane Transplantation Treating Recurrent Pterygium Trial","status":"COMPLETED","sponsor":"Yifeng Yu","startDate":"2021-03-01","conditions":"Recurrent Pterygium, Micro-Conjunctival Autografting Combined With Amniotic Membrane Transplantation","enrollment":40},{"nctId":"NCT03740880","phase":"NA","title":"Trigger Time in Advanced Maternal Age Patients With Low AMH","status":"TERMINATED","sponsor":"ART Fertility Clinics LLC","startDate":"2019-01-07","conditions":"the Number of Mature Oocytes","enrollment":1},{"nctId":"NCT01412879","phase":"PHASE2","title":"S1106 Rituximab With Combination Chemotherapy or Bendamustine Hydrochloride Followed by Consolidation Chemotherapy and Stem Cell Transplantation in Older Patients With Previously Untreated Mantle Cell Lymphoma","status":"COMPLETED","sponsor":"SWOG Cancer Research Network","startDate":"2011-11","conditions":"Lymphoma","enrollment":53},{"nctId":"NCT00918190","phase":"NA","title":"Late Onset Postoperative Nausea and Vomiting","status":"COMPLETED","sponsor":"King Khaled Eye Specialist Hospital","startDate":"2009-06","conditions":"Postoperative Nausea and Vomiting","enrollment":75},{"nctId":"NCT05077111","phase":"PHASE4","title":"A Comparative Study Between Regional Anesthesia in Thoracoscopes and the Conventional General Anesthesia","status":"UNKNOWN","sponsor":"Mohamed Reda Ashour","startDate":"2020-01-15","conditions":"Pleural Effusion, Malignant, Pleural Mesothelioma, Pleural Empyema","enrollment":40},{"nctId":"NCT05028907","phase":"PHASE4","title":"Evaluation of Lacrimal Punctal Changes by Anterior Segment Optical Coherence Tomography AS-OCT After Topical Combined Antibiotics and Steroids Treatment in Cases of Inflammatory Punctual Stenosis","status":"COMPLETED","sponsor":"Sohag University","startDate":"2020-11-15","conditions":"Ophthalmopathy , Lacrimal System","enrollment":64},{"nctId":"NCT04380818","phase":"NA","title":"Low Dose Anti-inflammatory Radiotherapy for the Treatment of Pneumonia by COVID-19","status":"UNKNOWN","sponsor":"Grupo de Investigación Clínica en Oncología Radioterapia","startDate":"2020-06-05","conditions":"Pneumonia, Viral","enrollment":106},{"nctId":"NCT04856397","phase":"NA","title":"Ozurdex in Suboptimal Diabetic Macular Edema Patients","status":"UNKNOWN","sponsor":"Uptown Eye Specialists","startDate":"2021-05-25","conditions":"Diabetic Macular Edema","enrollment":200},{"nctId":"NCT03440411","phase":"PHASE3","title":"Pom-dex Versus Pom-Cyclo-dex in MM Patients With Biochemical or Clinical Relapse, During Lena Maintenance Treatment","status":"TERMINATED","sponsor":"Fondazione EMN Italy Onlus","startDate":"2016-02-18","conditions":"Multiple Myeloma","enrollment":9},{"nctId":"NCT02897830","phase":"PHASE2","title":"Ixazomib, Lenalidomide, Dexamethasone Induction and Extended Consolidation Plus Lenalidomide Maintenance in Multiple Myeloma","status":"TERMINATED","sponsor":"University Hospital, Toulouse","startDate":"2016-08-05","conditions":"Multiple Myeloma","enrollment":46},{"nctId":"NCT04538300","phase":"NA","title":"Treatment of Postoperative Nausea-Vomiting in Laparoscopic Cholecystectomy: Peppermint-Flavored Gum Versus Gum-Free","status":"COMPLETED","sponsor":"Bursa Yuksek Ihtisas Training and Research Hospital","startDate":"2017-05-01","conditions":"Postoperative Nausea and Vomiting, Chewing Gum","enrollment":300},{"nctId":"NCT03789227","phase":"NA","title":"CT-guided Ablation of the Ganglion Impar for Pelvic Tumors: Comparethe Addition of Ketorolac or Dexamethasone","status":"COMPLETED","sponsor":"Mansoura University","startDate":"2018-07-01","conditions":"Pain, Chronic","enrollment":120},{"nctId":"NCT02556814","phase":"PHASE4","title":"Caffeic Acid Combining High-dose Dexamethasone in Management of ITP","status":"COMPLETED","sponsor":"Shandong University","startDate":"2015-09","conditions":"Immune Thrombocytopenia","enrollment":214},{"nctId":"NCT00166439","phase":"PHASE2","title":"Trial of Oxaliplatin, Cytosine Arabinoside, Dexamethasone With Rituxan (ROAD) in Patients With Relapsed Non-Hodgkins Lymphoma","status":"COMPLETED","sponsor":"Academic and Community Cancer Research United","startDate":"2005-03","conditions":"Lymphoma","enrollment":50},{"nctId":"NCT03446937","phase":"NA","title":"Effect of Antenatal Corticosteroids on Neonatal Morbidity.","status":"COMPLETED","sponsor":"Ahmadu Bello University Teaching Hospital","startDate":"2017-12-01","conditions":"Neonatal Respiratory Distress Syndrome","enrollment":150},{"nctId":"NCT01867710","phase":"PHASE2","title":"Abiraterone With Different Steroid Regimens for Side Effect Related to Mineralcorticoid Excess Prevention in Prostate Cancer Prior to Chemotherapy","status":"COMPLETED","sponsor":"Janssen Pharmaceutica N.V., Belgium","startDate":"2013-07-16","conditions":"Prostate Cancer","enrollment":164},{"nctId":"NCT00011362","phase":"PHASE3","title":"Dexamethasone Therapy in VLBW Infants at Risk of CLD","status":"COMPLETED","sponsor":"NICHD Neonatal Research Network","startDate":"1992-09","conditions":"Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age","enrollment":371},{"nctId":"NCT00807599","phase":"PHASE2","title":"Lenalidomide (Revlimid®) Plus Low-dose Dexamethasone (Ld x 4 Cycles) Then Stem Cell Collection Followed by Randomization to Continued Ld or Stem Cell Transplantation (SCT) Plus Maintenance L","status":"COMPLETED","sponsor":"Memorial Sloan Kettering Cancer Center","startDate":"2008-12-10","conditions":"Multiple Myeloma","enrollment":67},{"nctId":"NCT03334487","phase":"PHASE3","title":"Study Evaluating the Safety of Rovalpituzumab Tesirine for Third-Line and Later Treatment of Subjects With Relapsed or Refractory Small Cell Lung Cancer","status":"WITHDRAWN","sponsor":"AbbVie","startDate":"2018-03-15","conditions":"Small Cell Lung Cancer","enrollment":""},{"nctId":"NCT00781768","phase":"PHASE4","title":"Odansetron and Dexamethasone Alone vs. Odansetron, Dexamethason and Apreptant to Prevent Nausea","status":"COMPLETED","sponsor":"Loyola University","startDate":"2003-08","conditions":"Nausea, Vomiting","enrollment":181},{"nctId":"NCT00989781","phase":"NA","title":"Mechanisms of Increased Androgen Production Among Women With Polycystic Ovary Syndrome","status":"COMPLETED","sponsor":"University of California, San Diego","startDate":"2009-09","conditions":"Polycystic Ovary Syndrome","enrollment":41},{"nctId":"NCT00669877","phase":"PHASE2","title":"Rituximab and Hyper-CVAD (Cyclophosphamide, Vincristine, Adriamycin, and Dexamethasone) for Burkitt's and Burkitt's -Like Leukemia/Lymphoma","status":"COMPLETED","sponsor":"M.D. Anderson Cancer Center","startDate":"2002-08","conditions":"Burkitt's Lymphoma, Burkitt'S-like Lymphoma","enrollment":56},{"nctId":"NCT01193933","phase":"NA","title":"Multicenter Clinical Trial for Adult Ph-negative ALL. Non-intensive But Non-iterruptive Treatment","status":"UNKNOWN","sponsor":"National Research Center for Hematology, Russia","startDate":"2008-11","conditions":"Ph-negative Adult Acute Lymphoblastic Leukemia","enrollment":321},{"nctId":"NCT00375791","phase":"PHASE2","title":"Efficacy of Perifosine Alone and in Combination With Dexamethasone for Patients With Multiple Myeloma","status":"COMPLETED","sponsor":"AEterna Zentaris","startDate":"2005-12","conditions":"Multiple Myeloma","enrollment":67},{"nctId":"NCT01926665","phase":"PHASE1","title":"Carfilzomib Consolidation Therapy After Autologous Stem Cell Transplantation (ASCT) for Mantle Cell Lymphoma (MCL), T-cell Lymphoma (TCL), and Diffuse Large B-Cell Lymphoma (DLBCL)","status":"COMPLETED","sponsor":"M.D. Anderson Cancer Center","startDate":"2014-06-17","conditions":"Lymphoma","enrollment":2},{"nctId":"NCT01688362","phase":"PHASE1","title":"Platelet Rich Plasma vs. Corticosteroid Injection in the Treatment of Partial Rotator Cuff Tears","status":"TERMINATED","sponsor":"University of North Carolina, Chapel Hill","startDate":"2012-11","conditions":"Rotator Cuff Tear","enrollment":12},{"nctId":"NCT00096135","phase":"NA","title":"Combination Chemotherapy and Radiation Therapy in Treating Patients With Acute Lymphoblastic Leukemia That Has Relapsed in the CNS or Testes","status":"COMPLETED","sponsor":"Children's Oncology Group","startDate":"2004-11","conditions":"Leukemia","enrollment":168},{"nctId":"NCT01580020","phase":"PHASE4","title":"Extension Study to Compare Long-term Efficacy and Safety of Ranibizumab Intravitreal Injections Versus Dexamethasone Intravitreal Implant in Patients With RVO","status":"COMPLETED","sponsor":"Novartis Pharmaceuticals","startDate":"2012-05","conditions":"Retinal Vein Occlusion","enrollment":175},{"nctId":"NCT02351622","phase":"PHASE3","title":"Caffeic Acid Tablets as a Second-line Therapy for ITP","status":"COMPLETED","sponsor":"Shandong University","startDate":"2012-09","conditions":"Immune Thrombocytopenia","enrollment":103},{"nctId":"NCT02644720","phase":"NA","title":"Neural Compensation, Visual Function and Visual Quality After Monofocal or Multifocal Intraocular Lens Implantation","status":"UNKNOWN","sponsor":"Sun Yat-sen University","startDate":"2014-01","conditions":"Cataract","enrollment":50},{"nctId":"NCT00591643","phase":"PHASE1","title":"Adrenal Scans With Radioiodine-Labeled Norcholesterol (NP-59)","status":"COMPLETED","sponsor":"Memorial Sloan Kettering Cancer Center","startDate":"1977-07","conditions":"Adrenal Tumors, Adrenal Malignancies, Abnormal Hormonal Secretions","enrollment":93},{"nctId":"NCT01273480","phase":"PHASE1","title":"A Study to Assess the Potential Effects of Rifampin on the Pharmacokinetics of Trabectedin in Patients With Advanced Malignancies","status":"COMPLETED","sponsor":"Janssen Research & Development, LLC","startDate":"2010-12","conditions":"Neoplasm Metastases","enrollment":12},{"nctId":"NCT02234466","phase":"PHASE2","title":"Preoperative Oral Dexamethasone to Improve Recovery After Surgery","status":"UNKNOWN","sponsor":"University of Manitoba","startDate":"2014-08","conditions":"Breast Cancer","enrollment":80},{"nctId":"NCT01358253","phase":"PHASE4","title":"Rituximab Plus Chemotherapy for CD20+ Adult Acute Lymphoblastic Leukemia","status":"COMPLETED","sponsor":"Ruijin Hospital","startDate":"2010-12","conditions":"Acute Lymphoblastic Leukemia","enrollment":100},{"nctId":"NCT00002816","phase":"PHASE3","title":"Combination Chemotherapy in Treating Children With Relapsed Acute Lymphoblastic Leukemia","status":"COMPLETED","sponsor":"Children's Oncology Group","startDate":"1996-12","conditions":"Leukemia","enrollment":120},{"nctId":"NCT01134484","phase":"PHASE3","title":"VELCADE-Thalidomide-Dexamethasone (VTD) vs Thalidomide-Dexamethasone (TD) Incorporated Into Double Autotransplantation for Untreated Multiple Myeloma (MM)","status":"UNKNOWN","sponsor":"Michele Cavo","startDate":"2006-05","conditions":"Multiple Myeloma","enrollment":480},{"nctId":"NCT00975078","phase":"PHASE4","title":"Test Predicting Adrenal Insufficiency in Volunteers Under Prednisone Treatment","status":"COMPLETED","sponsor":"University Hospital, Basel, Switzerland","startDate":"2009-05","conditions":"Adrenal Gland Hypofunction","enrollment":39},{"nctId":"NCT00003728","phase":"PHASE3","title":"Combination Chemotherapy Plus Steroid Therapy in Treating Children With Acute Lymphoblastic Leukemia or Lymphoblastic Non-Hodgkin's Lymphoma","status":"UNKNOWN","sponsor":"European Organisation for Research and Treatment of Cancer - EORTC","startDate":"1998-12","conditions":"Leukemia, Lymphoma","enrollment":1500}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1852,"recentPublications":[{"date":"2026 Mar 9","pmid":"41897096","title":"Postnatal Steroids in Preterm Infants: A Narrative Review Series-Part 1: Inflammatory Modulation and Respiratory Impacts.","journal":"Children (Basel, Switzerland)"},{"date":"2026 Mar 11","pmid":"41849916","title":"Dexamethasone abolishes intra-day fluctuations of electrode impedance in cochlear implant users.","journal":"Hearing research"},{"date":"2026 Mar 13","pmid":"41826572","title":"The impact of body mass index on treatment response to high-dose dexamethasone in adult primary immune thrombocytopenia patients: A two-center retrospective study.","journal":"Internal and emergency medicine"},{"date":"2026","pmid":"41815330","title":"Concurrent Nivolumab-Induced Myocarditis and Myasthenia Gravis: A Case Report.","journal":"Case reports in oncological medicine"},{"date":"2026 Mar","pmid":"41787240","title":"Concurrent Sporadic Late-Onset Nemaline Myopathy and an Excessive Glycogen Accumulation Associated With Monoclonal Gammopathy.","journal":"European journal of neurology"}],"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Dexamethasone Late","genericName":"Dexamethasone Late","companyName":"NICHD Neonatal Research Network","companyId":"nichd-neonatal-research-network","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Dexamethasone is a synthetic glucocorticoid that suppresses inflammation and immune responses by binding to glucocorticoid receptors. Used for Prevention or treatment of chronic lung disease (bronchopulmonary dysplasia) in premature neonates requiring mechanical ventilation.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}