{"id":"dexamethasone-acefurate","rwe":[],"tags":[{"label":"Corticosteroid","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Anti-Inflammatory Agents","category":"pharmacology"},{"label":"Antiemetics","category":"pharmacology"},{"label":"Antineoplastic Agents","category":"pharmacology"},{"label":"Antineoplastic Agents, Hormonal","category":"pharmacology"},{"label":"Central Nervous System Agents","category":"pharmacology"},{"label":"Gastrointestinal Agents","category":"pharmacology"},{"label":"Glucocorticoids","category":"pharmacology"},{"label":"Hormones","category":"pharmacology"},{"label":"Peripheral Nervous System Agents","category":"pharmacology"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"dexamethasone cipecilate","offLabel":[],"synonyms":["dexamethasone acefurate","dexamethasone cipecilate"],"timeline":[],"approvals":[],"brandName":"Dexamethasone Cipecilate","ecosystem":[],"mechanism":{"moaClass":"Corticosteroid Hormone Receptor Agonists","modality":"Small Molecule","drugClass":"Corticosteroid","explanation":"Imagine your body's immune system as a fire alarm that goes off when it senses danger. Dexamethasone Cipecilate is like a fire alarm silencer that reduces the alarm's sensitivity, helping to calm down the immune response and reduce inflammation. This can be helpful for people with conditions like arthritis or asthma, but it's not suitable for everyone and can have side effects.","oneSentence":"Dexamethasone Cipecilate works by binding to glucocorticoid receptors in the body, which helps to reduce inflammation and suppress the immune system.","technicalDetail":"Dexamethasone Cipecilate exerts its effects by binding to glucocorticoid receptors (GR) in the cytoplasm, which then translocate to the nucleus and regulate the expression of target genes involved in inflammation and immune response."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/825","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=DEXAMETHASONE ACEFURATE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T10:36:09.947915","biosimilars":[],"competitors":[],"genericName":"dexamethasone acefurate","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"MMSL":"4552","NDDF":"002174","UNII":"W4N6E1T46B","CHEBI":"CHEBI:135819","VANDF":"4017922","INN_ID":"6060","RXNORM":"3264","UMLSCUI":"C2699606","ChEMBL_ID":"CHEMBL1697787","KEGG_DRUG":"D02591","DRUGBANK_ID":"DB01234","PDB_CHEM_ID":" DEX","PUBCHEM_CID":"656777","SNOMEDCT_US":"372584003","SECONDARY_CAS_RN":"132245-57-9","MESH_DESCRIPTOR_UI":"D003907"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":0,"therapeuticAreas":["Immunology"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Dexamethasone Cipecilate, also known as Dexamethasone Acefurate, is a corticosteroid small molecule. It is a synthetic derivative of cortisol, a naturally occurring hormone in the body. The exact target of Dexamethasone Cipecilate is unknown, but it is used to treat various inflammatory conditions. Its commercial status is currently unclear, and it may be patented or have generic manufacturers. As a corticosteroid, it has key safety considerations, including potential side effects such as increased blood sugar levels and changes in blood pressure.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}