{"id":"detajmium","rwe":[],"tags":[{"label":"detajmium","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Supraventricular arrhythmia","category":"indication"},{"label":"Ventricular arrhythmia","category":"indication"},{"label":"Anti-Arrhythmia Agents","category":"pharmacology"},{"label":"Cardiovascular Agents","category":"pharmacology"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"tachmalcor","offLabel":[],"synonyms":["detajmium","detajmium bitartrate","tachmalcor","detajmium bitartrate hydrate"],"timeline":[],"approvals":[],"brandName":"Tachmalcor","ecosystem":[{"indication":"Supraventricular arrhythmia","otherDrugs":[],"globalPrevalence":null},{"indication":"Ventricular arrhythmia","otherDrugs":[{"name":"bretylium","slug":"bretylium","company":"Intl Medication"},{"name":"disopyramide","slug":"disopyramide","company":"Gd Searle Llc"},{"name":"lidocaine","slug":"lidocaine","company":"Fresenius Kabi Usa"},{"name":"mexiletine","slug":"mexiletine","company":""}],"globalPrevalence":null}],"mechanism":{"modality":"Small Molecule","drugClass":"detajmium","explanation":"Think of your heart like a muscle that needs to beat in a regular rhythm. Sometimes, this rhythm can get disrupted, leading to abnormal heartbeats. Tachmalcor helps to stabilize the channels that control these heartbeats, allowing them to return to a normal rhythm.","oneSentence":"Tachmalcor works by stabilizing cardiac ion channels to regulate abnormal heart rhythms.","technicalDetail":"Tachmalcor is believed to exert its effects by modulating the activity of cardiac ion channels, specifically the potassium and sodium channels, to regulate the electrical activity of the heart and prevent arrhythmias."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/823","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=detajmium","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T10:35:58.050144","biosimilars":[],"competitors":[],"genericName":"detajmium","indications":{"approved":[{"name":"Supraventricular arrhythmia","source":"DrugCentral","snomedId":72654001,"regulator":"FDA"},{"name":"Ventricular arrhythmia","source":"DrugCentral","snomedId":44103008,"regulator":"FDA"}],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"006814","UNII":"BG60K165ZS","CHEBI":"CHEBI:135740","INN_ID":"3827","RXNORM":"236784","UMLSCUI":"C0075765","KEGG_DRUG":"D07794","PUBCHEM_CID":"118984402","SECONDARY_CAS_RN":"53862-81-0","MESH_SUPPLEMENTAL_RECORD_UI":"C036103"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":9,"therapeuticAreas":["Cardiovascular"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Tachmalcor (detajmium) is a small molecule drug in the detajmium class, developed for the treatment of supraventricular and ventricular arrhythmias. Its exact mechanism of action is not well-documented, but it is believed to work by stabilizing cardiac ion channels. The commercial status of Tachmalcor is unclear, and it may be patented or have generic manufacturers available. Further research is needed to determine its safety profile and efficacy in clinical settings.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":false,"score":2}}