{"id":"dermovat-ointment","safety":{"commonSideEffects":[{"rate":null,"effect":"Skin atrophy"},{"rate":null,"effect":"Striae"},{"rate":null,"effect":"Telangiectasia"},{"rate":null,"effect":"Local irritation or burning"},{"rate":null,"effect":"Systemic corticosteroid absorption (with prolonged use or occlusion)"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"anthropic-haiku","explanation":"Dermovat contains clobetasol propionate, a potent Class I (super-potent) topical corticosteroid that binds to glucocorticoid receptors in skin cells, suppressing inflammatory cytokine production and immune cell infiltration. This reduces erythema, pruritus, and other inflammatory manifestations of dermatological conditions when applied topically.","oneSentence":"Dermovat ointment is a topical corticosteroid that reduces inflammation and suppresses immune responses in the skin.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T03:10:22.681Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Inflammatory and pruritic dermatological conditions (e.g., psoriasis, eczema, lichen planus)"}]},"trialDetails":[{"nctId":"NCT00845481","phase":"PHASE2","title":"A Plaque Test Comparing the Anti-psoriatic Effect of Marketed Products for Topical Use for Psoriasis Vulgaris","status":"COMPLETED","sponsor":"LEO Pharma","startDate":"2009-01","conditions":"Psoriasis Vulgaris","enrollment":24}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":2,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_2","status":"active","brandName":"Dermovat ointment","genericName":"Dermovat ointment","companyName":"LEO Pharma","companyId":"leo-pharma","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Dermovat ointment is a topical corticosteroid that reduces inflammation and suppresses immune responses in the skin. Used for Inflammatory and pruritic dermatological conditions (e.g., psoriasis, eczema, lichen planus).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}