{"id":"delmadinone-acetate","rwe":[{"pmid":"27518315","year":"2016","title":"[Transient, secondary hypoadrenocorticism after treatment with delmadinone acetate (Tardastrex®) in a two year old male dog].","finding":"","journal":"Schweizer Archiv fur Tierheilkunde","studyType":"Clinical Study"},{"pmid":"27468035","year":"2016","title":"DIAGNOSIS AND MANAGEMENT OF BENIGN PROSTATIC HYPERPLASIA IN A PIED TAMARIN (SAGUINUS BICOLOR).","finding":"","journal":"Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians","studyType":"Clinical Study"},{"pmid":"25777477","year":"2015","title":"Simultaneous determination of seven gestagens in kidney fats by Ultra Performance Convergence Chromatography tandem mass spectrometry.","finding":"","journal":"Journal of chromatography. B, Analytical technologies in the biomedical and life sciences","studyType":"Clinical Study"},{"pmid":"19680939","year":"2009","title":"Confirmatory method for the determination of various acetylgestagens in animal kidney fat using liquid chromatography-tandem mass spectrometry.","finding":"","journal":"Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment","studyType":"Clinical Study"},{"pmid":"18689779","year":"2008","title":"Efficacies of osaterone and delmadinone in the treatment of benign prostatic hyperplasia in dogs.","finding":"","journal":"The Veterinary record","studyType":"Clinical Study"}],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Androgen Antagonists","category":"pharmacology"},{"label":"Hormone Antagonists","category":"pharmacology"},{"label":"Hormones","category":"pharmacology"},{"label":"Progestins","category":"pharmacology"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"zenadrex","offLabel":[],"synonyms":["delmadinone acetate","zenadrex"],"timeline":[],"approvals":[],"brandName":"Zenadrex","ecosystem":[],"mechanism":{"modality":"Small Molecule","explanation":"Imagine your body's cells have locks on them, and Delmadinone Acetate is a key that fits into those locks. When it binds to the locks, it sends a signal to the cell to do something specific, like reducing inflammation or suppressing the immune system. This is a simplified explanation of how Delmadinone Acetate works at a molecular level.","oneSentence":"Delmadinone Acetate is a synthetic steroid that works by binding to specific receptors in the body to produce its therapeutic effects.","technicalDetail":"Delmadinone Acetate is a synthetic corticosteroid with a 17,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione acetate structure. It is a potent inhibitor of inflammatory and immune responses, exerting its effects through the glucocorticoid receptor (GR) and mineralocorticoid receptor (MR) pathways."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3130","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=DELMADINONE ACETATE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T10:31:17.995228","biosimilars":[],"competitors":[],"genericName":"delmadinone acetate","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"92833M0LD9","CHEBI":"CHEBI:135645","INN_ID":"2870","UMLSCUI":"C0521958","ChEMBL_ID":"CHEMBL2104598","KEGG_DRUG":"D03675","PUBCHEM_CID":"10135765","SNOMEDCT_US":"126118003","SECONDARY_CAS_RN":"15262-77-8","MESH_SUPPLEMENTAL_RECORD_UI":"C005928"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":11,"therapeuticAreas":["Immunology"],"biosimilarFilings":[],"recentPublications":[{"date":"2016 Mar","pmid":"27518315","title":"[Transient, secondary hypoadrenocorticism after treatment with delmadinone acetate (Tardastrex®) in a two year old male dog].","journal":"Schweizer Archiv fur Tierheilkunde"},{"date":"2016 Jun","pmid":"27468035","title":"DIAGNOSIS AND MANAGEMENT OF BENIGN PROSTATIC HYPERPLASIA IN A PIED TAMARIN (SAGUINUS BICOLOR).","journal":"Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians"},{"date":"2015 Apr 15","pmid":"25777477","title":"Simultaneous determination of seven gestagens in kidney fats by Ultra Performance Convergence Chromatography tandem mass spectrometry.","journal":"Journal of chromatography. B, Analytical technologies in the biomedical and life sciences"},{"date":"2009 May","pmid":"19680939","title":"Confirmatory method for the determination of various acetylgestagens in animal kidney fat using liquid chromatography-tandem mass spectrometry.","journal":"Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment"},{"date":"2008 Aug 9","pmid":"18689779","title":"Efficacies of osaterone and delmadinone in the treatment of benign prostatic hyperplasia in dogs.","journal":"The Veterinary record"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Zenadrex, also known as Delmadinone Acetate, is a small molecule medication with unknown target and drug class. Its commercial status is unclear, and it has not been approved by the FDA for any indications. As a result, there is limited information available on its pharmacokinetics, safety, and efficacy. Further research is needed to determine its potential therapeutic applications and risks. Due to the lack of available data, it is challenging to provide a comprehensive summary of Zenadrex.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}