{"id":"decamethoxine","rwe":[{"pmid":"41244684","year":"2025","title":"Modern antiseptics against multidrug-resistant Pseudomonas aeruginosa, emerging from war-related injuries in Ukraine.","finding":"","journal":"Frontiers in microbiology","studyType":"Clinical Study"},{"pmid":"37720142","year":"2023","title":"The effect of local anesthetics against planktonic forms and film formation of S. aureus strains and its dependence on antiseptics activity.","finding":"","journal":"Frontiers in microbiology","studyType":"Clinical Study"},{"pmid":"36267170","year":"2022","title":"In vitro evaluation of the antimicrobial activity of antiseptics against clinical Acinetobacter baumannii strains isolated from combat wounds.","finding":"","journal":"Frontiers in microbiology","studyType":"Clinical Study"},{"pmid":"35315409","year":"2022","title":"Research of the activity of local anesthetics and antiseptics regarding clinical isolates of Acinetobacter baumannii as pathogens of postoperative infectious complications.","finding":"","journal":"Acta bio-medica : Atenei Parmensis","studyType":"Clinical Study"},{"pmid":"31658704","year":"2019","title":"Naturally Drug-Loaded Chitin: Isolation and Applications.","finding":"","journal":"Marine drugs","studyType":"Clinical Study"}],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"D08AJ10","category":"atc"},{"label":"Active","category":"status"},{"label":"Antiseptic preparation","category":"indication"},{"label":"Anti-Bacterial Agents","category":"pharmacology"},{"label":"Anti-Infective Agents","category":"pharmacology"},{"label":"Anti-Infective Agents, Local","category":"pharmacology"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"decametoxin","offLabel":[],"synonyms":["decamethoxine","decamethoxin","decamethoxinum","decametoxin"],"timeline":[],"approvals":[],"brandName":"Decametoxin","ecosystem":[{"indication":"Antiseptic preparation","otherDrugs":[{"name":"boric acid","slug":"boric-acid","company":""},{"name":"chloroxylenol","slug":"chloroxylenol","company":""},{"name":"ethanol","slug":"ethanol","company":"B Braun"},{"name":"hydrogen peroxide","slug":"hydrogen-peroxide","company":""}],"globalPrevalence":null}],"mechanism":{"modality":"Small Molecule","explanation":"Imagine decametoxin as a strong detergent that breaks down the protective layer around bacteria and other microorganisms, causing them to die and preventing them from multiplying. This action helps to prevent or treat infections in wounds or on the skin. By targeting the cell membranes of microorganisms, decametoxin can effectively reduce the risk of infection.","oneSentence":"Decametoxin works by disrupting the cell membranes of microorganisms, ultimately leading to their death.","technicalDetail":"Decametoxin's exact mechanism of action is unknown, but it is believed to interact with the cell membranes of microorganisms, altering their permeability and leading to cell lysis and death."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/4919","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=decamethoxine","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T10:26:08.456544","biosimilars":[],"competitors":[{"drugName":"benzalkonium","drugSlug":"benzalkonium","fdaApproval":"","relationship":"same-class"},{"drugName":"cetylpyridinium","drugSlug":"cetylpyridinium","fdaApproval":"","relationship":"same-class"},{"drugName":"benzethonium","drugSlug":"benzethonium","fdaApproval":"","relationship":"same-class"}],"genericName":"decamethoxine","indications":{"approved":[{"name":"Antiseptic preparation","source":"DrugCentral","snomedId":261276004,"regulator":"FDA"}],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"benzalkonium","brandName":"benzalkonium","genericName":"benzalkonium","approvalYear":"","relationship":"same-class"},{"drugId":"cetylpyridinium","brandName":"cetylpyridinium","genericName":"cetylpyridinium","approvalYear":"","relationship":"same-class"},{"drugId":"benzethonium","brandName":"benzethonium","genericName":"benzethonium","approvalYear":"","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"81I73K1HKN","CHEBI":"CHEBI:134717","UMLSCUI":"C0057232","ChEMBL_ID":"CHEMBL3707368","DRUGBANK_ID":"DB13705","PUBCHEM_CID":"162290","MESH_SUPPLEMENTAL_RECORD_UI":"C000858"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":33,"therapeuticAreas":["Infectious Disease"],"atcClassification":{"source":"DrugCentral","atcCode":"D08AJ10","allCodes":["D08AJ10"]},"biosimilarFilings":[],"recentPublications":[{"date":"2025","pmid":"41244684","title":"Modern antiseptics against multidrug-resistant Pseudomonas aeruginosa, emerging from war-related injuries in Ukraine.","journal":"Frontiers in microbiology"},{"date":"2023","pmid":"37720142","title":"The effect of local anesthetics against planktonic forms and film formation of S. aureus strains and its dependence on antiseptics activity.","journal":"Frontiers in microbiology"},{"date":"2022","pmid":"36267170","title":"In vitro evaluation of the antimicrobial activity of antiseptics against clinical Acinetobacter baumannii strains isolated from combat wounds.","journal":"Frontiers in microbiology"},{"date":"2022 Mar 14","pmid":"35315409","title":"Research of the activity of local anesthetics and antiseptics regarding clinical isolates of Acinetobacter baumannii as pathogens of postoperative infectious complications.","journal":"Acta bio-medica : Atenei Parmensis"},{"date":"2019 Oct 10","pmid":"31658704","title":"Naturally Drug-Loaded Chitin: Isolation and Applications.","journal":"Marine drugs"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Decametoxin is a small molecule with synonyms including DECAMETHOXINE, MM-692, and SEPTEFRIL. Its exact mechanism and clinical uses are not specified in the provided information.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":false,"score":2}}