{"id":"deanol","rwe":[{"pmid":"37735938","year":"2023","title":"Determination of urinary deanol-N-oxide excretion profiles after ingestion of nutritional supplements containing deanol.","finding":"","journal":"Drug testing and analysis","studyType":"Clinical Study"},{"pmid":"20301320","year":"1993","title":"Neuroferritinopathy.","finding":"","journal":"","studyType":"Clinical Study"},{"pmid":"34656936","year":"2022","title":"A generic gas chromatography method for determination of residual solvents in PET radiopharmaceuticals.","finding":"","journal":"Journal of pharmaceutical and biomedical analysis","studyType":"Clinical Study"},{"pmid":"32155458","year":"2020","title":"Surfactant-free and rinsing-resistant biodegradable nanoparticles with high adsorption on natural fibers for the long-lasting release of fragrances.","finding":"","journal":"Colloids and surfaces. 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Korsakova","studyType":"Clinical Study"}],"tags":[{"label":"deanol","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"N06BX04","category":"atc"},{"label":"Active","category":"status"},{"label":"Anti-Dyskinesia Agents","category":"pharmacology"},{"label":"Antidepressive Agents","category":"pharmacology"},{"label":"Central Nervous System Agents","category":"pharmacology"},{"label":"Psychotropic Drugs","category":"pharmacology"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"bimanol","offLabel":[],"synonyms":["dimethylaminoethanol","deanol","norcholine","dimethylethanolamine","bimanol","liparon","varesal","rexolin"],"timeline":[],"approvals":[],"brandName":"Bimanol","ecosystem":[],"mechanism":{"target":"Creatine transporter, High affinity choline transporter 1","modality":"Small Molecule","drugClass":"deanol","explanation":"Think of neurotransmitters like messengers that help different parts of the brain talk to each other. Bimanol helps increase the amount of these messengers, which can improve communication between brain cells and potentially treat certain conditions. This can lead to improved mood, focus, and other cognitive functions.","oneSentence":"Bimanol increases levels of neurotransmitters such as dopamine and norepinephrine in the brain.","technicalDetail":"Bimanol is believed to work by inhibiting the enzyme monoamine oxidase (MAO), which breaks down neurotransmitters such as dopamine and norepinephrine. By preventing the breakdown of these neurotransmitters, Bimanol increases their levels in the brain, leading to improved neurotransmission and potential therapeutic effects."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/787","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://clinicaltrials.gov/search?intr=deanol","fields":["trials"],"source":"ClinicalTrials.gov"},{"id":3,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=deanol","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T10:30:10.259373","biosimilars":[],"competitors":[{"drugName":"Choline C-11","drugSlug":"choline-c-11","fdaApproval":"2012-09-12","genericCount":4,"patentStatus":"Off-patent — generic available","relationship":"same-target"},{"drugName":"cetylpyridinium","drugSlug":"cetylpyridinium","fdaApproval":"","relationship":"same-target"},{"drugName":"choline","drugSlug":"choline","fdaApproval":"","genericCount":12,"patentStatus":"Off-patent — generic available","relationship":"same-target"}],"dataSources":[{"url":"https://drugcentral.org","name":"DrugCentral","fields":["indications","contraindications","safety","target","drugInteractions"],"retrievedDate":"2026-04-07"}],"genericName":"deanol","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"choline-c-11","brandName":"Choline C-11","genericName":"Choline C-11","approvalYear":"2012","relationship":"same-target"},{"drugId":"cetylpyridinium","brandName":"cetylpyridinium","genericName":"cetylpyridinium","approvalYear":"","relationship":"same-target"},{"drugId":"choline","brandName":"choline","genericName":"choline","approvalYear":"","relationship":"same-target"}],"trialDetails":[{"nctId":"NCT07477288","phase":"PHASE2","title":"Effectiveness of a Bilayering Serum and Cream Containing GABA, DMAE, Cysteamine, and Bakuchiol for Skin Whitening and Anti-Aging","status":"COMPLETED","sponsor":"Hasanuddin University","startDate":"2025-03-12","conditions":["Skin Aging"],"enrollment":44,"completionDate":"2025-12-29"},{"nctId":"NCT04481282","phase":"PHASE2","title":"The Combination of Terbutaline and Danazol as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia","status":"UNKNOWN","sponsor":"Peking University People's Hospital","startDate":"2020-07-08","conditions":["Immune Thrombocytopenia"],"enrollment":40,"completionDate":"2021-07-31"},{"nctId":"NCT03460808","phase":"PHASE1,PHASE2","title":"The Combination of Atorvastatin, Acetylcysteine and Danazol as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia","status":"UNKNOWN","sponsor":"Peking University People's Hospital","startDate":"2018-03-10","conditions":["Immune Thrombocytopenia"],"enrollment":200,"completionDate":"2023-01-01"},{"nctId":"NCT01667263","phase":"PHASE2","title":"The Combination of ATRA and Danazol as Second-line Treatment in Adult Immune Thrombocytopenia","status":"COMPLETED","sponsor":"Peking University People's Hospital","startDate":"2012-06-01","conditions":["Autoimmune Thrombocytopenia"],"enrollment":130,"completionDate":"2017-02-01"}],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"administration":{},"crossReferences":{"NUI":"N0000166807","NDDF":"001541","UNII":"2N6K9DRA24","CHEBI":"CHEBI:271436","VANDF":"4036720","RXNORM":"3116","UMLSCUI":"C0011064","ChEMBL_ID":"CHEMBL122588","KEGG_DRUG":"D07777","DRUGBANK_ID":"DB13352","PUBCHEM_CID":"7902","SNOMEDCT_US":"7904003","MESH_DESCRIPTOR_UI":"D003642"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":151,"therapeuticAreas":["Neuroscience"],"atcClassification":{"source":"DrugCentral","atcCode":"N06BX04","allCodes":["N06BX04"]},"biosimilarFilings":[],"recentPublications":[{"date":"2023 Nov-Dec","pmid":"37735938","title":"Determination of urinary deanol-N-oxide excretion profiles after ingestion of nutritional supplements containing deanol.","journal":"Drug testing and analysis"},{"date":"1993","pmid":"20301320","title":"Neuroferritinopathy.","journal":""},{"date":"2022 Jan 5","pmid":"34656936","title":"A generic gas chromatography method for determination of residual solvents in PET radiopharmaceuticals.","journal":"Journal of pharmaceutical and biomedical analysis"},{"date":"2020 Jun","pmid":"32155458","title":"Surfactant-free and rinsing-resistant biodegradable nanoparticles with high adsorption on natural fibers for the long-lasting release of fragrances.","journal":"Colloids and surfaces. 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