{"id":"dazhu-rhodiola-rosea-capsule","safety":{"commonSideEffects":[{"rate":null,"effect":"Headache"},{"rate":null,"effect":"Dizziness"},{"rate":null,"effect":"Dry mouth"},{"rate":null,"effect":"Insomnia (if taken late in day)"}]},"_chembl":{"chemblId":"CHEMBL206253","moleculeType":"Small molecule","molecularWeight":"578.60"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Rhodiola rosea is an adaptogenic herb that contains bioactive compounds (salidroside, rosavins) which are believed to regulate serotonin, dopamine, and norepinephrine levels in the central nervous system. It may also reduce hypothalamic-pituitary-adrenal (HPA) axis hyperactivity and cortisol elevation during stress, thereby improving cognitive function, mood, and physical endurance.","oneSentence":"Rhodiola rosea extract enhances stress resilience and mental performance by modulating neurotransmitter systems and reducing cortisol-mediated stress responses.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:31:53.251Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Stress-related fatigue and mental exhaustion"},{"name":"Cognitive performance and concentration enhancement"},{"name":"Mood support and mild depression symptoms"}]},"trialDetails":[{"nctId":"NCT03633890","phase":"PHASE4","title":"DaZhu Rhodiola Rosea Capsule for Coronary Artery Disease With Angina Pectoris","status":"UNKNOWN","sponsor":"Beijing Anzhen Hospital","startDate":"2018-08","conditions":"Coronary Artery Disease","enrollment":102}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"DaZhu Rhodiola Rosea Capsule","genericName":"DaZhu Rhodiola Rosea Capsule","companyName":"Beijing Anzhen Hospital","companyId":"beijing-anzhen-hospital","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Rhodiola rosea extract enhances stress resilience and mental performance by modulating neurotransmitter systems and reducing cortisol-mediated stress responses. Used for Stress-related fatigue and mental exhaustion, Cognitive performance and concentration enhancement, Mood support and mild depression symptoms.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}