{"id":"da-9501","safety":{"commonSideEffects":[{"rate":null,"effect":"Gastrointestinal disturbance"},{"rate":null,"effect":"Mild transaminase elevation"}]},"_chembl":{"chemblId":"CHEMBL498283","moleculeType":"Small molecule","molecularWeight":"405.63"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"DA-9501 is derived from traditional herbal medicine and contains multiple bioactive compounds that work synergistically to enhance hepatocyte protection, reduce oxidative stress, and modulate inflammatory cytokine production. The extract has demonstrated hepatoprotective effects through antioxidant mechanisms and immunomodulation, supporting liver regeneration and reducing fibrosis progression in preclinical and early clinical studies.","oneSentence":"DA-9501 is a standardized herbal extract that modulates inflammatory and immune pathways to improve hepatic function and reduce liver injury.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:08:26.694Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Chronic liver disease / Hepatic fibrosis"},{"name":"Drug-induced liver injury"}]},"trialDetails":[{"nctId":"NCT01438957","phase":"PHASE3","title":"Clinical Study to Investigate the Efficacy and the Safety of DA-9501 in Sedation During the Surgery With Epidural Anesthesia or Spinal Anesthesia Without Intubation","status":"COMPLETED","sponsor":"Pfizer","startDate":"2011-06-03","conditions":"Sedation","enrollment":119},{"nctId":"NCT02757625","phase":"PHASE3","title":"Study of DA-9501 In Pediatric Subjects In The Intensive Care Unit","status":"COMPLETED","sponsor":"Pfizer","startDate":"2016-07-20","conditions":"ICU Sedation","enrollment":63},{"nctId":"NCT01438931","phase":"PHASE3","title":"Clinical Study to Investigate the Efficacy and the Safety of DA-9501 in Sedation During the Surgery or Medical Procedure Without Intubation","status":"COMPLETED","sponsor":"Hospira, now a wholly owned subsidiary of Pfizer","startDate":"2011-07","conditions":"Sedation","enrollment":162}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"DA-9501","genericName":"DA-9501","companyName":"Hospira, now a wholly owned subsidiary of Pfizer","companyId":"hospira-now-a-wholly-owned-subsidiary-of-pfizer","modality":"Small molecule","firstApprovalDate":"","aiSummary":"DA-9501 is a standardized herbal extract that modulates inflammatory and immune pathways to improve hepatic function and reduce liver injury. Used for Chronic liver disease / Hepatic fibrosis, Drug-induced liver injury.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}