{"id":"cynara-scolymus","_fda":{"id":"9ed39c86-6061-4b0b-8691-c9d6adee55f5","set_id":"0aac4f4f-8f71-44fa-906f-2bf35afea431","openfda":{"nui":["N0000175415","M0014874","N0000009909","N0000185375","N0000175629","N0000184306","N0000185001","M0000728","M0016962"],"unii":["9N3437ZUU0","C9642I91WL","15443PR153","3D10KUA6BM","G59M7S0WS3","N94C2U587S","KPS1B1162N","6YR2608RSU"],"route":["ORAL"],"spl_id":["9ed39c86-6061-4b0b-8691-c9d6adee55f5"],"brand_name":["GLAUTARAKT"],"spl_set_id":["0aac4f4f-8f71-44fa-906f-2bf35afea431"],"package_ndc":["59469-131-10"],"product_ndc":["59469-131"],"generic_name":["GOLD TRICHLORIDE, SOLANUM DULCAMARA TOP, EUPHRASIA STRICTA, NITROGLYCERIN, HEDERA HELIX FLOWERING TWIG, RUTA GRAVEOLENS FLOWERING TOP, TOBACCO LEAF, AND CYNARA SCOLYMUS WHOLE"],"product_type":["HUMAN OTC DRUG"],"pharm_class_cs":["Nitrates [CS]","Allergens [CS]","Plant Proteins [CS]"],"pharm_class_pe":["Vasodilation [PE]","Increased Histamine Release [PE]","Cell-mediated Immunity [PE]","Increased IgG Production [PE]"],"substance_name":["CYNARA SCOLYMUS WHOLE","EUPHRASIA STRICTA","GOLD TRICHLORIDE","HEDERA HELIX FLOWERING TWIG","NITROGLYCERIN","RUTA GRAVEOLENS FLOWERING TOP","SOLANUM DULCAMARA TOP","TOBACCO LEAF"],"pharm_class_epc":["Nitrate Vasodilator [EPC]","Non-Standardized Plant Allergenic Extract [EPC]"],"manufacturer_name":["PEKANA Naturheilmittel GmbH"],"is_original_packager":[true]},"purpose":["For relief of occasional overexertion of the eyes. Application of this homeopathic remedy for the designated usage is exclusively based on homeopathic experience. With severe forms of this disease, a clinically proven therapy is indicated."],"version":"5","warnings":["Warning If symptoms persist, contact a licensed practitioner. If you have known sensitivity to any of the ingredients, please consult your licensed practitioner before use. If you are pregnant or nursing a baby, seek the advice of a health care professional before use. Keep out of the reach of children. Protect from light and heat. Tamper Evident Do not use this product if tamper evident strip is broken or removed from base of cap."],"questions":["To report adverse events, contact BioResource at 321B Blodgett Street, Cotati, CA 94931"],"ask_doctor":["If symptoms persist, contact a licensed practitioner. If you have known sensitivity to any of the ingredients, please consult your licensed practitioner before use. If you are pregnant or nursing a baby, seek the advice of a health care professional before use."],"effective_time":"20221215","active_ingredient":["Ingredients: Aurum chloratum 6X Cynara scolymus 8X Euphrasia officinalis 2X Nitroglycerinum (Glonoinum) 6X Hedera helix 8X Nicotiana tabacum 6X Ruta graveolens 6X Solanum dulcamara (Dulcamara) 3X Selected ingredients prepared by spagyric processes."],"inactive_ingredient":["Contains 20% alcohol by volume."],"storage_and_handling":["Protect from light and heat."],"indications_and_usage":["Indications For relief of occasional overexertion of the eyes. Application of this homeopathic remedy for the designated usage is exclusively based on homeopathic experience. With severe forms of this disease, a clinically proven therapy is indicated."],"active_ingredient_table":["
Ingredients:
Aurum chloratum6X
Cynara scolymus8X
Euphrasia officinalis2X
Nitroglycerinum (Glonoinum)6X
Hedera helix8X
Nicotiana tabacum6X
Ruta graveolens6X
Solanum dulcamara (Dulcamara)3X
"],"spl_unclassified_section":["Distributed by: BioResource Inc. Cotati, CA 94931 Manufactured by: PEKANA ® GmbH D-88353 Kisslegg"],"dosage_and_administration":["Dosage Unless otherwise prescribed, adults take 15-20 drops, 3 times per day. For pediatric dosages, consult your practitioner."],"spl_product_data_elements":["GLAUTARAKT Gold Trichloride, Solanum dulcamara Top, Euphrasia Stricta, Nitroglycerin, Hedera helix Flowering Twig, Ruta graveolens Flowering Top, Tobacco Leaf, and Cynara scolymus Whole Gold Trichloride Gold Cation (3+) Solanum dulcamara Top Solanum Dulcamara Top Euphrasia Stricta Euphrasia Stricta Nitroglycerin Nitroglycerin Hedera helix Flowering Twig Hedera helix Flowering Twig Ruta graveolens Flowering Top Ruta graveolens Flowering Top Tobacco Leaf Tobacco Leaf Cynara scolymus Whole Cynara Scolymus Whole Water Alcohol"],"keep_out_of_reach_of_children":["Keep out of the reach of children."],"package_label_principal_display_panel":["PRINCIPAL DISPLAY PANEL - 50 ml Bottle Box GLAUTARAKT ™ Oral Drops Homeopathic Medicine For relief of occasional overexertion of the eyes For Oral Use Only Do Not Put In Eyes 1.7 FL OZ (50 ml) PEKANA ® PRINCIPAL DISPLAY PANEL - 50 ml Bottle Box"]},"safety":{"boxedWarnings":[]},"_chembl":null,"_sources":{"trials":{"url":"https://clinicaltrials.gov/search?intr=Cynara Scolymus","method":"api_direct","source":"ClinicalTrials.gov","rawText":"","confidence":1,"sourceType":"ctgov","retrievedAt":"2026-04-20T07:20:24.429971+00:00"},"regulatory.ca":{"url":"","method":"api_direct","source":"Health Canada DPD","rawText":"","confidence":1,"sourceType":"health_canada_dpd","retrievedAt":"2026-04-20T07:20:31.031902+00:00"},"publicationCount":{"url":"https://pubmed.ncbi.nlm.nih.gov/?term=Cynara Scolymus","method":"api_direct","source":"PubMed/NCBI","rawText":"","confidence":1,"sourceType":"pubmed","retrievedAt":"2026-04-20T07:20:31.805716+00:00"},"mechanism.drugClass":{"url":"https://api.fda.gov/drug/label.json","method":"deterministic","source":"FDA Label (EPC)","rawText":"","confidence":1,"sourceType":"fda_label","retrievedAt":"2026-04-20T07:20:21.891221+00:00"},"administration.route":{"url":"","method":"deterministic","source":"FDA Label","rawText":"","confidence":1,"sourceType":"fda_label","retrievedAt":"2026-04-20T07:20:21.891266+00:00"},"indications.approved":{"url":"","method":"ai_extraction","source":"FDA Label + AI","aiModel":"featherless","rawText":"","confidence":0.9,"sourceType":"fda_label","retrievedAt":"2026-04-20T07:20:40.427251+00:00"},"safety.boxedWarnings":{"url":"","method":"deterministic","source":"FDA Label (no boxed warning)","rawText":"","confidence":1,"sourceType":"fda_label","retrievedAt":"2026-04-20T07:20:21.891276+00:00"}},"_dailymed":{"setId":"c803733e-b5e2-46f2-bdfe-b239f38d9312","title":"TOTAL BODY DETOX (ALUMINA, BRYONIA, CALCAREA IODATA, CANTHARIS, CARDUUS BENEDICTUS, CARDUUS MAR, CHELIDONIUM MAJ, CINCHONA OFFICINALIS, CYNARA SCOLYMUS, DIOSCOREA VILLOSA, HEPAR SULPHURIS CALCAREUM, IRIS VERSICOLOR, JUNIPERUS COMMUNIS, KALI IODATUM, MERCURIUS CORROSIVUS, MERCURIUS VIVUS, NATRUM CARBONICUM, NUX VOMICA, PLUMBUM METALLICUM, PTELEA TRIFOLIATA, RICINUS COMMUNIS, ROBINIA PSEUDOACACIA, SERUM ANGUILLAE, SOLIDAGO VIRGAUREA, SULPHUR, SULPHURICUM ACIDUM AND TARAXACUM OFFICINALE.) LIQUID [KING BIO INC.]"},"mechanism":{"drugClass":"Nitrate Vasodilator [EPC]"},"_scrapedAt":"2026-03-28T00:45:36.100Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"_validation":{"fieldsValidated":1,"lastValidatedAt":"2026-04-20T07:20:40.947974+00:00","fieldsConflicting":0,"overallConfidence":0.95},"indications":{"approved":[{"id":"cynara-scolymus-relief-of-occasional-eye-overe","name":"Relief of occasional eye overexertion","dosing":null,"approvals":[],"diseaseId":"","eligibility":"General population","pivotalTrial":null,"restrictions":[],"patientPopulation":"General population","diagnosticRequired":null,"brandNameForIndication":""}]},"trialDetails":[{"nctId":"NCT07475299","phase":"NA","title":"Synbiotic Supplement With Botanical Extracts for Gut Microbiota Balance in Irritable Bowel Syndrome","status":"NOT_YET_RECRUITING","sponsor":"Iuliu Hatieganu University of Medicine and Pharmacy","startDate":"2026-04","conditions":"Irritable Bowel Syndrome 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