{"id":"cyfluthrin","rwe":[{"pmid":"41826680","year":"2026","title":"Residential proximity to agricultural pesticide exposures during preconception and pregnancy and associations with Apgar scores in the Az-PEAR study (2006-2020).","finding":"","journal":"Journal of exposure science & environmental epidemiology","studyType":"Clinical Study"},{"pmid":"41824294","year":"2026","title":"Beyond mortality: biological performance of Trichogramma atopovirilia (Hymenoptera: Trichogrammatidae) exposed to citrus insecticides.","finding":"","journal":"Journal of economic entomology","studyType":"Clinical Study"},{"pmid":"41752623","year":"2026","title":"Mitochondrial Gene Expression as a Novel Biomarker for Detecting and Discriminating Neurotoxic Pesticide Exposure in Ramulus phyllodeus (Chen & He, 2008).","finding":"","journal":"Insects","studyType":"Clinical Study"},{"pmid":"41715232","year":"2026","title":"Development of a multiplex SNaPshot assay for simultaneous detection of multiple insecticide-resistance mutations in Anopheles sinensis.","finding":"","journal":"Parasites & vectors","studyType":"Clinical Study"},{"pmid":"41638136","year":"2026","title":"A novel carboxylesterase Est3617 from a food-fermentation bacterium for rapid remediation of β-cyfluthrin in environment and food.","finding":"","journal":"Journal of hazardous materials","studyType":"Clinical Study"}],"tags":[{"label":"cyfluthrin","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"P03BA01","category":"atc"},{"label":"Active","category":"status"},{"label":"Insecticides","category":"pharmacology"},{"label":"Pesticides","category":"pharmacology"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":["cyfluthrin"],"offLabel":[],"synonyms":["cyfluthrin"],"timeline":[],"approvals":[],"ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"cyfluthrin","explanation":"Imagine your nervous system as a complex electrical grid. Cyfluthrin is like a power outage that disrupts the flow of signals, causing the insect's muscles to become paralyzed and unable to function. This leads to the insect's death.","oneSentence":"Cyfluthrin works by disrupting the insect nervous system, ultimately leading to paralysis and death.","technicalDetail":"Cyfluthrin acts as a voltage-gated sodium channel blocker, preventing the normal flow of sodium ions into the insect's neurons and disrupting the electrical impulses that control muscle contraction."},"_wikipedia":{"url":"https://en.wikipedia.org/wiki/Cyfluthrin","title":"Cyfluthrin","extract":"Cyfluthrin is a pyrethroid insecticide and common household pesticide. It is a complex organic compound and the commercial product is sold as a mixture of isomers. Like most pyrethroids, it is highly toxic to fish and invertebrates, but it is far less toxic to humans. It is generally supplied as a 10–25% liquid concentrate for commercial use and is diluted prior to spraying onto agricultural crops and outbuildings."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/4407","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=cyfluthrin","fields":["publications"],"source":"PubMed/NCBI"},{"id":3,"url":"https://en.wikipedia.org/wiki/Cyfluthrin","fields":["history","overview"],"source":"Wikipedia"}],"_enrichedAt":"2026-03-30T10:22:19.133672","biosimilars":[],"competitors":[],"genericName":"cyfluthrin","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"SCM2QLZ6S0","CHEBI":"CHEBI:4034","UMLSCUI":"C0056836","ChEMBL_ID":"CHEMBL2104608","KEGG_DRUG":"D07761","DRUGBANK_ID":"DB13828","PUBCHEM_CID":"104926","MESH_SUPPLEMENTAL_RECORD_UI":"C052570"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":780,"therapeuticAreas":["Neuroscience"],"atcClassification":{"source":"DrugCentral","atcCode":"P03BA01","allCodes":["P03BA01"]},"biosimilarFilings":[],"recentPublications":[{"date":"2026 Mar 13","pmid":"41826680","title":"Residential proximity to agricultural pesticide exposures during preconception and pregnancy and associations with Apgar scores in the Az-PEAR study (2006-2020).","journal":"Journal of exposure science & environmental epidemiology"},{"date":"2026 Mar 13","pmid":"41824294","title":"Beyond mortality: biological performance of Trichogramma atopovirilia (Hymenoptera: Trichogrammatidae) exposed to citrus insecticides.","journal":"Journal of economic entomology"},{"date":"2026 Feb 20","pmid":"41752623","title":"Mitochondrial Gene Expression as a Novel Biomarker for Detecting and Discriminating Neurotoxic Pesticide Exposure in Ramulus phyllodeus (Chen & He, 2008).","journal":"Insects"},{"date":"2026 Feb 19","pmid":"41715232","title":"Development of a multiplex SNaPshot assay for simultaneous detection of multiple insecticide-resistance mutations in Anopheles sinensis.","journal":"Parasites & vectors"},{"date":"2026 Feb 15","pmid":"41638136","title":"A novel carboxylesterase Est3617 from a food-fermentation bacterium for rapid remediation of β-cyfluthrin in environment and food.","journal":"Journal of hazardous materials"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","brandName":"cyfluthrin","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Cyfluthrin is a small molecule pyrethroid insecticide used as a household pesticide, commonly supplied as a 10-25% liquid concentrate for commercial use. It is highly toxic to fish and invertebrates but relatively less toxic to humans.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}