{"id":"cyclosporine-ophthalmic-solution-0-05","safety":{"commonSideEffects":[{"rate":null,"effect":"Ocular irritation/burning"},{"rate":null,"effect":"Conjunctival hyperemia"},{"rate":null,"effect":"Transient blurred vision"},{"rate":null,"effect":"Foreign body sensation"}]},"_chembl":null,"_fixedAt":"2026-03-30T13:16:15.221402","_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Cyclosporine binds to cyclophilin and inhibits calcineurin, a phosphatase required for T-cell activation and IL-2 production. 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Used for Dry eye disease (keratoconjunctivitis sicca), Ocular inflammation associated with dry eye.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}