{"id":"cyclopentobarbital","rwe":[{"pmid":"21819796","year":"2010","title":"Tissue distribution of newer anticonvulsant drugs in postmortem cases.","finding":"","journal":"Journal of analytical toxicology","studyType":"Clinical Study"},{"pmid":"10814127","year":"2000","title":"Palladium-catalyzed asymmetric allylic alkylation of barbituric acid derivatives: enantioselective syntheses of cyclopentobarbital and pentobarbital.","finding":"","journal":"The Journal of organic chemistry","studyType":"Clinical Study"},{"pmid":"2079506","year":"1990","title":"Identification and differentiation of barbiturates, other sedative-hypnotics and their metabolites in urine integrated in a general screening procedure using computerized gas chromatography-mass spectrometry.","finding":"","journal":"Journal of chromatography","studyType":"Clinical Study"}],"tags":[{"label":"cyclopentobarbital","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"allylpental","offLabel":[],"synonyms":["cyclopentobarbital","allylcyclopentenylbarbital","allylpental","cyclopental","cyclopentenylallylbarbituric acid","cyclopentobarbitone"],"timeline":[],"approvals":[],"brandName":"Allylpental","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"cyclopentobarbital","explanation":"Imagine your brain is a busy city with many different streets and intersections. Allylpental helps calm down the traffic by increasing the activity of a specific chemical messenger, or neurotransmitter, that helps slow down the pace of the city. This results in feelings of relaxation and reduced anxiety.","oneSentence":"Allylpental works by enhancing the activity of a neurotransmitter in the brain, leading to sedation and relaxation.","technicalDetail":"Allylpental is a barbiturate that acts as a GABA_A receptor agonist, enhancing the activity of the inhibitory neurotransmitter GABA and leading to sedative and hypnotic effects."},"_wikipedia":{"url":"https://en.wikipedia.org/wiki/Cyclopentobarbital","title":"Cyclopentobarbital","extract":"Cyclopentobarbital sodium is a barbiturate derivative invented in the 1940s. It has sedative and anticonvulsant properties, and was used primarily as an anaesthetic in veterinary medicine. Cyclopal is considered similar in effects to phenobarbital but lasts almost three times as long, and is considered a long-acting barbiturate with a fairly slow onset of action."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3723","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=cyclopentobarbital","fields":["publications"],"source":"PubMed/NCBI"},{"id":3,"url":"https://en.wikipedia.org/wiki/Cyclopentobarbital","fields":["history","overview"],"source":"Wikipedia"}],"_enrichedAt":"2026-03-30T10:22:03.178478","biosimilars":[],"competitors":[],"genericName":"cyclopentobarbital","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"2230XWG55Q","CHEBI":"CHEBI:134951","UMLSCUI":"C0961379","PUBCHEM_CID":"6454","MESH_SUPPLEMENTAL_RECORD_UI":"C414527"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":3,"therapeuticAreas":["Neuroscience"],"biosimilarFilings":[],"recentPublications":[{"date":"2010 Oct","pmid":"21819796","title":"Tissue distribution of newer anticonvulsant drugs in postmortem cases.","journal":"Journal of analytical toxicology"},{"date":"2000 Mar 10","pmid":"10814127","title":"Palladium-catalyzed asymmetric allylic alkylation of barbituric acid derivatives: enantioselective syntheses of cyclopentobarbital and pentobarbital.","journal":"The Journal of organic chemistry"},{"date":"1990 Sep 14","pmid":"2079506","title":"Identification and differentiation of barbiturates, other sedative-hypnotics and their metabolites in urine integrated in a general screening procedure using computerized gas chromatography-mass spectrometry.","journal":"Journal of chromatography"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Allylpental, also known as cyclopentobarbital, is a small molecule drug in the cyclopentobarbital class. Its mechanism of action and target are unknown, and it is not FDA-approved for any indications. As a result, there is limited information available on its commercial status, safety considerations, or pharmacokinetic properties. Further research is needed to fully understand this compound. Allylpental's development history is also unclear.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}