{"id":"cyclopentamine","rwe":[{"pmid":"37080997","year":"2023","title":"Design of C(1)-symmetric tridentate ligands for enantioselective dearomative [3 + 2] annulation of indoles with aminocyclopropanes.","finding":"","journal":"Nature communications","studyType":"Clinical Study"},{"pmid":"11331","year":"1976","title":"Simultaneous semiautomated assay of pyrrobutamine phosphate, cyclopentamine hydrochloride, and methapyrilene hydrochloride in pharmaceutical mixtures.","finding":"","journal":"Journal of pharmaceutical sciences","studyType":"Clinical Study"},{"pmid":"5116035","year":"1971","title":"Actions of dexamphetamine and amphetamine-like amines in chickens with brain transections.","finding":"","journal":"British journal of pharmacology","studyType":"Clinical Study"},{"pmid":"4390216","year":"1969","title":"In vitro evaluation of a series of sympathomimetic amines and the beta-adrenergic blocking properties of cyclopentamine.","finding":"","journal":"Journal of pharmaceutical sciences","studyType":"Clinical Study"},{"pmid":"14209515","year":"1964","title":"A NONSYMPATHOMIMETIC EFFECT OF CYCLOPENTAMINE AND BETA-MERCAPTOETHYLAMINE IN THE RABBIT ILEUM.","finding":"","journal":"The Journal of pharmacology and experimental therapeutics","studyType":"Clinical Study"}],"tags":[{"label":"cyclopentamine","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"R01AA02","category":"atc"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"cyclonarol","offLabel":[],"synonyms":["cyclopentamine","cyclopentamin","cyclopentadrine","cyclonarol"],"timeline":[],"approvals":[],"brandName":"Cyclonarol","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"cyclopentamine","explanation":"Unfortunately, the exact mechanism of action of cyclonarol is not well understood, but it is thought to work by binding to a specific site on a target molecule, which triggers a series of downstream effects that ultimately lead to its therapeutic benefits.","oneSentence":"Cyclonarol works by interacting with a specific target to produce its therapeutic effect.","technicalDetail":"The technical details of cyclonarol's mechanism of action are not specified, but it is likely to involve a complex interplay of molecular interactions and signaling pathways."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/755","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=CYCLOPENTAMINE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T10:21:56.281002","biosimilars":[],"competitors":[{"drugName":"ephedrine","drugSlug":"ephedrine","fdaApproval":"","patentExpiry":"May 16, 2040","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"phenylephrine","drugSlug":"phenylephrine","fdaApproval":"1952-01-21","patentExpiry":"Sep 26, 2036","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"oxymetazoline","drugSlug":"oxymetazoline","fdaApproval":"1986-05-30","patentExpiry":"May 2, 2028","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"tetryzoline","drugSlug":"tetryzoline","fdaApproval":"1979-11-30","relationship":"same-class"},{"drugName":"xylometazoline","drugSlug":"xylometazoline","fdaApproval":"","relationship":"same-class"},{"drugName":"naphazoline","drugSlug":"naphazoline","fdaApproval":"1971-06-07","genericCount":6,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"epinephrine","drugSlug":"epinephrine","fdaApproval":"1948-11-19","patentExpiry":"Oct 20, 2036","patentStatus":"Patent protected","relationship":"same-class"}],"genericName":"cyclopentamine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"ephedrine","brandName":"ephedrine","genericName":"ephedrine","approvalYear":"","relationship":"same-class"},{"drugId":"phenylephrine","brandName":"phenylephrine","genericName":"phenylephrine","approvalYear":"1952","relationship":"same-class"},{"drugId":"oxymetazoline","brandName":"oxymetazoline","genericName":"oxymetazoline","approvalYear":"1986","relationship":"same-class"},{"drugId":"tetryzoline","brandName":"tetryzoline","genericName":"tetryzoline","approvalYear":"1979","relationship":"same-class"},{"drugId":"xylometazoline","brandName":"xylometazoline","genericName":"xylometazoline","approvalYear":"","relationship":"same-class"},{"drugId":"naphazoline","brandName":"naphazoline","genericName":"naphazoline","approvalYear":"1971","relationship":"same-class"},{"drugId":"epinephrine","brandName":"epinephrine","genericName":"epinephrine","approvalYear":"1948","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"004729","UNII":"WB9Q6M8O60","CHEBI":"CHEBI:134766","INN_ID":"135","RXNORM":"59094","UMLSCUI":"C0163082","ChEMBL_ID":"CHEMBL329203","KEGG_DRUG":"D07370","DRUGBANK_ID":"DB08999","PUBCHEM_CID":"7608","SNOMEDCT_US":"62444006","MESH_SUPPLEMENTAL_RECORD_UI":"C013459"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":7,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"R01AA02","allCodes":["R01AA02"]},"biosimilarFilings":[],"recentPublications":[{"date":"2023 Apr 20","pmid":"37080997","title":"Design of C(1)-symmetric tridentate ligands for enantioselective dearomative [3 + 2] annulation of indoles with aminocyclopropanes.","journal":"Nature communications"},{"date":"1976 Nov","pmid":"11331","title":"Simultaneous semiautomated assay of pyrrobutamine phosphate, cyclopentamine hydrochloride, and methapyrilene hydrochloride in pharmaceutical mixtures.","journal":"Journal of pharmaceutical sciences"},{"date":"1971 Aug","pmid":"5116035","title":"Actions of dexamphetamine and amphetamine-like amines in chickens with brain transections.","journal":"British journal of pharmacology"},{"date":"1969 Jul","pmid":"4390216","title":"In vitro evaluation of a series of sympathomimetic amines and the beta-adrenergic blocking properties of cyclopentamine.","journal":"Journal of pharmaceutical sciences"},{"date":"1964 Jul","pmid":"14209515","title":"A NONSYMPATHOMIMETIC EFFECT OF CYCLOPENTAMINE AND BETA-MERCAPTOETHYLAMINE IN THE RABBIT ILEUM.","journal":"The Journal of pharmacology and experimental therapeutics"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Cyclonarol is a small molecule compound with the synonyms CICLOPENTAMINA, CLOPANE, CYCLOPENTAMINE, and CYCLOPENTAMINE.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}