{"id":"cycles-n5-and-n6","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Fatigue"},{"rate":"5-10%","effect":"Nausea"},{"rate":"5-10%","effect":"Vomiting"},{"rate":"5-10%","effect":"Diarrhea"},{"rate":"5-10%","effect":"Anemia"}]},"_chembl":{"chemblId":"CHEMBL4466372","moleculeType":"Unknown","molecularWeight":"368.35"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"While the exact mechanism is unclear, it is thought that Cycles N5 and N6 may play a role in the regulation of cell cycle progression, potentially through interactions with cyclin-dependent kinases or other cell cycle regulators. Further research is needed to fully understand their mechanism of action.","oneSentence":"Cycles N5 and N6 are likely involved in the regulation of cell cycle progression.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:08:11.162Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Treatment of various cancers"}]},"trialDetails":[{"nctId":"NCT06071897","phase":"PHASE3","title":"Induction Chemoimmunotherapy for Patients With High-risk Neuroblastoma","status":"RECRUITING","sponsor":"Federal Research Institute of Pediatric Hematology, Oncology and Immunology","startDate":"2023-09-01","conditions":"Neuroblastoma, Ganglioneuroblastoma","enrollment":15},{"nctId":"NCT03042429","phase":"PHASE3","title":"Combination Chemotherapy Followed by Stem Cell Transplant in High-risk Neuroblastoma Patients","status":"COMPLETED","sponsor":"University of Cologne","startDate":"2007-01-01","conditions":"Neuroblastoma","enrollment":360}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["cisplatin, vindesine, ifosfamide, dacarbacine, doxorubicine"],"phase":"phase_3","status":"active","brandName":"Cycles N5 and N6","genericName":"Cycles N5 and N6","companyName":"University of Cologne","companyId":"university-of-cologne","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Cycles N5 and N6 are likely involved in the regulation of cell cycle progression. Used for Treatment of various cancers.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}