{"id":"cyclandelate","rwe":[],"tags":[{"label":"cyclandelate","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"C04AX01","category":"atc"},{"label":"Active","category":"status"},{"label":"Cardiovascular Agents","category":"pharmacology"},{"label":"Vasodilator Agents","category":"pharmacology"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"cyclolyt","offLabel":[],"synonyms":["cyclandelate","cyclergine","cyclobral","cyclolyt","cyclomandol"],"timeline":[],"approvals":[],"brandName":"Cyclolyt","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"cyclandelate","explanation":"Imagine your blood vessels are like roads in your body. Cyclolyt helps to improve the flow of traffic on these roads, making it easier for oxygen and nutrients to reach your cells. This can be especially helpful for people with conditions that affect blood flow.","oneSentence":"Cyclolyt works by affecting blood vessel function and improving circulation.","technicalDetail":"Cyclolyt is believed to exert its effects through a combination of vasodilation and improved microcirculation, although the precise molecular mechanisms are not well-characterized."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/747","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=CYCLANDELATE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T10:23:52.491756","_validation":{"fieldsValidated":1,"lastValidatedAt":"2026-04-20T11:15:30.977630+00:00","fieldsConflicting":0,"overallConfidence":0.95},"biosimilars":[],"competitors":[{"drugName":"phenoxybenzamine","drugSlug":"phenoxybenzamine","fdaApproval":"1953-01-26","genericCount":6,"patentStatus":"Off-patent — generic available","relationship":"same-class"}],"genericName":"cyclandelate","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"phenoxybenzamine","brandName":"phenoxybenzamine","genericName":"phenoxybenzamine","approvalYear":"1953","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NUI":"N0000146399","MMSL":"212","NDDF":"000696","UNII":"4139O1OAY2","VUID":"4018058","CHEBI":"CHEBI:3988","VANDF":"4018058","INN_ID":"821","RXNORM":"2970","UMLSCUI":"C0010525","ChEMBL_ID":"CHEMBL1480987","KEGG_DRUG":"D00286","DRUGBANK_ID":"DB04838","PUBCHEM_CID":"2893","SNOMEDCT_US":"387405003","MESH_DESCRIPTOR_UI":"D003495"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":143,"therapeuticAreas":["Hematology"],"atcClassification":{"source":"DrugCentral","atcCode":"C04AX01","allCodes":["C04AX01"]},"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Cyclolyt (CYCLANDELATE) is a small molecule drug in the cyclandelate class. Its exact target is unknown, but it is used to treat certain conditions. The commercial status of Cyclolyt is unclear, and it may be patented or have generic manufacturers. Key safety considerations are not well-documented. Further research is needed to fully understand its pharmacology and clinical use.","enrichmentLevel":5,"visitCount":0,"regulatoryByCountry":[{"country_code":"CA","regulator":"Health Canada","status":"approved","approval_date":null,"mah":"","brand_name_local":"","application_number":""}],"trialStats":{"total":0,"withResults":0},"validation":{"fieldsValidated":1,"lastValidatedAt":"2026-04-20T11:15:30.977630+00:00","fieldsConflicting":0,"overallConfidence":0.95},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}