{"id":"cyb004","safety":{"commonSideEffects":[{"rate":"null","effect":"Increased heart rate"},{"rate":"null","effect":"Anxiety"},{"rate":"null","effect":"Hallucinations"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"Serotonin 5-HT2A receptor agonists, such as CYB004, are known to induce altered states of consciousness and have been studied for their potential therapeutic applications in treating various mental health conditions.","oneSentence":"CYB004 is a psychedelic compound that acts as a serotonin 5-HT2A receptor agonist.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T03:30:04.204Z","_scrapedBy":"cloudflare-swarm","_wikipedia":{"url":"https://en.wikipedia.org/wiki/HLP004","title":"HLP004","extract":"HLP004, or HLP-004, also known as deuterated dimethyltryptamine (dDMT) and formerly as CYB004, is a serotonergic psychedelic related to dimethyltryptamine (DMT) which is under development for the treatment of generalized anxiety disorder. It is administered by inhalation or intravenous injection. The drug is a tryptamine derivative and is a deuterated analogue and form of DMT."},"indications":{"approved":[{"name":"Treatment-resistant depression"}]},"trialDetails":[{"nctId":"NCT06051721","phase":"PHASE2","title":"A Study of a N, N-dimethyltryptamine (DMT) Analog (CYB004) in Participants With Generalized Anxiety Disorder (GAD)","status":"ACTIVE_NOT_RECRUITING","sponsor":"Cybin IRL Limited","startDate":"2024-05-10","conditions":"Generalized Anxiety Disorder","enrollment":36}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_2","status":"active","brandName":"CYB004","genericName":"CYB004","companyName":"Cybin IRL Limited","companyId":"cybin-irl-limited","modality":"Small molecule","firstApprovalDate":"","aiSummary":"CYB004 is a psychedelic compound that acts as a serotonin 5-HT2A receptor agonist. Used for Treatment-resistant depression.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}