{"id":"ct327-ointment","safety":{"commonSideEffects":[{"rate":"null","effect":"Skin irritation"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"CT327 ointment works by activating the CB2 receptor, which is involved in the regulation of inflammation and pain. This activation leads to a reduction in pro-inflammatory cytokines and an increase in anti-inflammatory cytokines, resulting in decreased pain and inflammation.","oneSentence":"CT327 ointment is a topical treatment that targets the cannabinoid receptor type 2 (CB2) to reduce inflammation and pain.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T03:29:53.650Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Treatment of pain associated with psoriasis"}]},"trialDetails":[{"nctId":"NCT01808157","phase":"PHASE2","title":"A Study to Evaluate the Efficacy, Safety and Tolerability of CT327 in Atopic Dermatitis","status":"COMPLETED","sponsor":"Creabilis SA","startDate":"2013-07","conditions":"Atopic Dermatitis","enrollment":188},{"nctId":"NCT01465282","phase":"PHASE2","title":"Evaluation of the Efficacy, Safety and Toleration of CT327 Ointment in Patients With Psoriasis Vulgaris","status":"COMPLETED","sponsor":"Creabilis SA","startDate":"2011-12","conditions":"Psoriasis Vulgaris","enrollment":160}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_2","status":"active","brandName":"CT327 ointment","genericName":"CT327 ointment","companyName":"Creabilis SA","companyId":"creabilis-sa","modality":"Small molecule","firstApprovalDate":"","aiSummary":"CT327 ointment is a topical treatment that targets the cannabinoid receptor type 2 (CB2) to reduce inflammation and pain. Used for Treatment of pain associated with psoriasis.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}