{"id":"cropropamide","rwe":[{"pmid":"22609153","year":"2012","title":"Effects of doxapram, prethcamide and lobeline on spirometric, blood gas and acid-base variables in healthy new-born calves.","finding":"","journal":"Veterinary journal (London, England : 1997)","studyType":"Clinical Study"},{"pmid":"19951756","year":"2010","title":"Simultaneous analysis of fourteen tertiary amine stimulants in human urine for doping control purposes by liquid chromatography-tandem mass spectrometry and gas chromatography-mass spectrometry.","finding":"","journal":"Analytica chimica acta","studyType":"Clinical Study"},{"pmid":"18082653","year":"2008","title":"Parallel analysis of stimulants in saliva and urine by gas chromatography/mass spectrometry: perspectives for \"in competition\" anti-doping analysis.","finding":"","journal":"Analytica chimica acta","studyType":"Clinical Study"},{"pmid":"16459125","year":"2006","title":"Amyotrophic lateral sclerosis in an Italian professional soccer player.","finding":"","journal":"Parkinsonism & related disorders","studyType":"Clinical Study"},{"pmid":"9127276","year":"1997","title":"Pharmacokinetics of intravenous and oral prethcamide in horses.","finding":"","journal":"Journal of pharmaceutical and biomedical analysis","studyType":"Clinical Study"}],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"propylbutamide","offLabel":[],"synonyms":["cropropamide","propylbutamide"],"timeline":[],"approvals":[],"brandName":"Propylbutamide","ecosystem":[],"mechanism":{"modality":"Small Molecule","explanation":"Imagine your body's cells are like locks, and Propylbutamide is a key that fits into those locks. When it binds to the right lock, it can turn on or off certain cellular processes, which can help treat a disease. However, the exact lock it fits into and how it works is still a mystery.","oneSentence":"Propylbutamide is a small molecule that works by binding to specific biological molecules to produce its effects.","technicalDetail":"Propylbutamide is a small molecule that likely interacts with specific proteins or receptors to produce its therapeutic effects, but the precise molecular mechanism remains unknown."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/743","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=CROPROPAMIDE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T10:23:22.163858","biosimilars":[],"competitors":[],"genericName":"cropropamide","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"W8TYE9V9BX","CHEBI":"CHEBI:134981","INN_ID":"306","UMLSCUI":"C0056512","ChEMBL_ID":"CHEMBL2106529","KEGG_DRUG":"D07754","PUBCHEM_CID":"5369258","SECONDARY_CAS_RN":"3544-46-5","MESH_SUPPLEMENTAL_RECORD_UI":"C015089"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":7,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"2012 Nov","pmid":"22609153","title":"Effects of doxapram, prethcamide and lobeline on spirometric, blood gas and acid-base variables in healthy new-born calves.","journal":"Veterinary journal (London, England : 1997)"},{"date":"2010 Jan 4","pmid":"19951756","title":"Simultaneous analysis of fourteen tertiary amine stimulants in human urine for doping control purposes by liquid chromatography-tandem mass spectrometry and gas chromatography-mass spectrometry.","journal":"Analytica chimica acta"},{"date":"2008 Jan 14","pmid":"18082653","title":"Parallel analysis of stimulants in saliva and urine by gas chromatography/mass spectrometry: perspectives for \"in competition\" anti-doping analysis.","journal":"Analytica chimica acta"},{"date":"2006 Jun","pmid":"16459125","title":"Amyotrophic lateral sclerosis in an Italian professional soccer player.","journal":"Parkinsonism & related disorders"},{"date":"1997 Feb","pmid":"9127276","title":"Pharmacokinetics of intravenous and oral prethcamide in horses.","journal":"Journal of pharmaceutical and biomedical analysis"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Propylbutamide, also known as CROPROPAMIDE, is a small molecule drug with unknown target and drug class. Its commercial status is unclear, and it is not FDA approved for any indications. As a small molecule, it is likely to work by interacting with specific biological molecules, but the exact mechanism is unknown. Further research is needed to understand its potential therapeutic applications and safety profile.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}