{"id":"counseling-chc","safety":{"commonSideEffects":[]},"_chembl":{"chemblId":"CHEMBL76602","moleculeType":"Small molecule","molecularWeight":"189.17"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This is a psychosocial intervention rather than a pharmacological drug. It combines counseling—including cognitive-behavioral therapy and motivational enhancement—with contingency management (incentive-based reinforcement), where patients receive rewards for meeting treatment goals such as abstinence or medication adherence. The approach targets the behavioral and psychological drivers of substance use disorders.","oneSentence":"Counseling combined with contingency management (CHC) uses behavioral reinforcement and motivational interviewing to modify substance use behaviors.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:07:42.604Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Substance use disorder (likely opioid or stimulant use disorder)"},{"name":"Medication adherence support in addiction treatment"}]},"trialDetails":[{"nctId":"NCT06160947","phase":"NA","title":"The Effect of Chiropractic Care on Opioid Use for Chronic Spinal Pain: A Feasibility Study","status":"NOT_YET_RECRUITING","sponsor":"McMaster University","startDate":"2026-04-01","conditions":"Back Pain","enrollment":24},{"nctId":"NCT04447209","phase":"NA","title":"Dietary Diversity of Young Children During CoVID-19 Outbreak: A Longitudinal Study","status":"COMPLETED","sponsor":"University of Malaya","startDate":"2020-06-06","conditions":"Dietary Diversity","enrollment":350},{"nctId":"NCT06044636","phase":"NA","title":"Early Digi-physical Support During Breastfeeding Initiation","status":"UNKNOWN","sponsor":"Region Stockholm","startDate":"2023-01-18","conditions":"Breastfeeding, Self Efficacy, Breastfeeding Duration","enrollment":320},{"nctId":"NCT01688167","phase":"NA","title":"Increasing Availability and Acceptability of Circumcision in Zambia","status":"COMPLETED","sponsor":"University of Miami","startDate":"2012-01","conditions":"HIV","enrollment":1468},{"nctId":"NCT01850745","phase":"","title":"Multidisciplinary Support Program in Chronic Hepatitis C","status":"COMPLETED","sponsor":"Parc de Salut Mar","startDate":"2003-01","conditions":"Hepatitis C, Chronic","enrollment":447},{"nctId":"NCT00574067","phase":"PHASE3","title":"Buprenorphine for Prisoners","status":"COMPLETED","sponsor":"Friends Research Institute, Inc.","startDate":"2008-09","conditions":"Heroin Addiction","enrollment":213},{"nctId":"NCT02480062","phase":"NA","title":"mWELLCARE:An Integrated mHealth System for the Prevention and Care of Chronic Disease","status":"COMPLETED","sponsor":"Public Health Foundation of India","startDate":"2016-04","conditions":"Hypertension, Diabetes, Depression","enrollment":3702},{"nctId":"NCT02616458","phase":"NA","title":"The Impact of Ear Pain Anticipatory Guidance Counseling on Otitis Related Visits in a Low Income Population","status":"COMPLETED","sponsor":"University of Colorado, Denver","startDate":"2010-11","conditions":"Otitis Media","enrollment":310}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Suboxone"],"phase":"phase_3","status":"active","brandName":"Counseling +CHC","genericName":"Counseling +CHC","companyName":"Friends Research Institute, Inc.","companyId":"friends-research-institute-inc","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Counseling combined with contingency management (CHC) uses behavioral reinforcement and motivational interviewing to modify substance use behaviors. Used for Substance use disorder (likely opioid or stimulant use disorder), Medication adherence support in addiction treatment.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":true,"score":3}}