{"id":"cosamin-ds-nutramax","safety":{"commonSideEffects":[{"rate":null,"effect":"Gastrointestinal upset (nausea, dyspepsia)"},{"rate":null,"effect":"Headache"},{"rate":null,"effect":"Allergic reactions (rare, shellfish-derived glucosamine)"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Glucosamine is thought to provide building blocks for cartilage repair and may stimulate cartilage-producing cells (chondrocytes), while chondroitin may help retain water in cartilage and inhibit cartilage-degrading enzymes. Together, these components are proposed to slow cartilage breakdown and support joint function in degenerative joint disease.","oneSentence":"Cosamin DS is a dietary supplement containing glucosamine and chondroitin that may help maintain cartilage structure and reduce joint inflammation in osteoarthritis.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:07:47.124Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Osteoarthritis pain and joint function support"}]},"trialDetails":[{"nctId":"NCT00955552","phase":"PHASE3","title":"Efficacy and Safety Study of Glucosamine/Chondroitin Sulfate to Patients Treatment With Osteoarthrosis of the Knee","status":"COMPLETED","sponsor":"Eurofarma Laboratorios S.A.","startDate":"2010-08","conditions":"Osteoarthritis of the Knee","enrollment":100}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":2,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Cosamin DS®","glucosamine hydrochloride and chondroitin sulphate"],"phase":"phase_3","status":"active","brandName":"Cosamin DS® (Nutramax)","genericName":"Cosamin DS® (Nutramax)","companyName":"Eurofarma Laboratorios S.A.","companyId":"eurofarma-laboratorios-s-a","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Cosamin DS is a dietary supplement containing glucosamine and chondroitin that may help maintain cartilage structure and reduce joint inflammation in osteoarthritis. Used for Osteoarthritis pain and joint function support.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}