{"id":"cord-blood","safety":{"commonSideEffects":[{"rate":null,"effect":"Graft-versus-host disease (GVHD)"},{"rate":null,"effect":"Graft failure or delayed engraftment"},{"rate":null,"effect":"Infection"},{"rate":null,"effect":"Hemorrhage"},{"rate":null,"effect":"Organ toxicity"}]},"_chembl":{"chemblId":"CHEMBL4594461","moleculeType":"Unknown"},"_dailymed":{"setId":"251fd4cb-4aa4-4473-9f89-968da856eb77","title":"STERILE CORD BLOOD COLLECTION UNIT (MSC128D) (ANTICOAGULANT CITRATE PHOSPHATE DEXTROSE SOLUTION) INJECTION, SOLUTION [MACO PRODUCTIONS]"},"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Umbilical cord blood contains CD34+ hematopoietic stem cells capable of self-renewal and multilineage differentiation into myeloid, lymphoid, and erythroid lineages. When cryopreserved and transplanted, these cells can reconstitute hematopoietic and immune function in patients with hematologic malignancies, inherited metabolic disorders, and immunodeficiencies. The therapeutic benefit derives from the stem cells' ability to engraft in bone marrow and restore normal blood cell production.","oneSentence":"Cord blood is a source of hematopoietic stem cells and progenitor cells that can differentiate into various blood cell types and immune cells for therapeutic transplantation.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:31:17.023Z","_scrapedBy":"cloudflare-swarm","_wikipedia":{"url":"https://en.wikipedia.org/wiki/Cord_blood","title":"Cord blood","extract":"Cord blood is blood that remains in the placenta and in the attached umbilical cord after childbirth. Cord blood is collected because it contains stem cells, which can be used to treat hematopoietic and genetic disorders such as cancer."},"indications":{"approved":[{"name":"Acute leukemia in remission"},{"name":"Chronic leukemia"},{"name":"Myelodysplastic syndrome"},{"name":"Lymphoma"},{"name":"Multiple myeloma"},{"name":"Inherited metabolic disorders"},{"name":"Severe aplastic anemia"},{"name":"Severe combined immunodeficiency"}]},"trialDetails":[{"nctId":"NCT01648855","phase":"","title":"Consequences of Antiangiogenic Factors Involved in Preeclampsia on Intra-uterine Growth Restricted Preterm Newborn","status":"COMPLETED","sponsor":"Assistance Publique - Hôpitaux de Paris","startDate":"2012-06","conditions":"Preterm Birth, Intra-uterine Growth Restriction, Maternal Preeclampsia","enrollment":33},{"nctId":"NCT06880003","phase":"NA","title":"Cord Blood Preptin Levels in Infants","status":"COMPLETED","sponsor":"Konya City Hospital","startDate":"2025-03-10","conditions":"Newborn 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