{"id":"contraceptive-vaginal-ring","safety":{"commonSideEffects":[{"rate":null,"effect":"Vaginal irritation or discomfort"},{"rate":null,"effect":"Headache"},{"rate":null,"effect":"Nausea"},{"rate":null,"effect":"Breast tenderness"},{"rate":null,"effect":"Vaginal discharge"},{"rate":null,"effect":"Mood changes"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The vaginal ring is a flexible polymer device that continuously releases contraceptive hormones over three weeks. The hormones suppress the luteinizing hormone (LH) surge needed for ovulation, while also altering cervical mucus viscosity to impede sperm transport. This provides systemic contraceptive efficacy with lower hormone doses than oral formulations due to direct vaginal absorption.","oneSentence":"Releases hormones (typically ethinyl estradiol and a progestin) directly into the vaginal tissue to prevent ovulation and thicken cervical mucus.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:31:07.091Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Contraception in women of reproductive age"}]},"trialDetails":[{"nctId":"NCT01223313","phase":"NA","title":"A Multicenter, Open-Label, Non-Comparative Study of the Safety and Contraceptive Efficacy of the Woman's Condom","status":"COMPLETED","sponsor":"Premier Research","startDate":"2011-01","conditions":"Contraception","enrollment":511},{"nctId":"NCT00455156","phase":"PHASE3","title":"Study of the Safety, Efficacy and Cycle Control of a Contraceptive Vaginal Ring","status":"COMPLETED","sponsor":"Premier Research","startDate":"2006-12","conditions":"Contraception","enrollment":1200},{"nctId":"NCT04257500","phase":"PHASE4","title":"Does Vaginal Delivery of Combined Hormonal Contraception Affect the Risk of Metabolic Syndrome in Overweight/Obese Women With PCOS","status":"COMPLETED","sponsor":"Andrea Roe, MD, MPH","startDate":"2020-09-03","conditions":"Polycystic Ovary Syndrome","enrollment":22},{"nctId":"NCT07083635","phase":"PHASE2","title":"Transdermal Ethinyl Estradiol and Norelgestromin for Irregular Bleeding in Contraceptive Implant Users","status":"RECRUITING","sponsor":"Chulalongkorn University","startDate":"2025-07-29","conditions":"Menstruation Disturbances, Metrorrhagia, Uterine Hemorrhage","enrollment":40},{"nctId":"NCT01586000","phase":"PHASE2","title":"A Dose-finding Study to Evaluate the Effect of a Contraceptive Vaginal Ring, Releasing Nestorone® and Estradiol, on Cycle Control, Ovulation Inhibition, and Pharmacokinetics in Normal Cycling Women","status":"COMPLETED","sponsor":"Kimberly Myer","startDate":"2012-03","conditions":"Suppression of Ovulation","enrollment":197},{"nctId":"NCT03432416","phase":"PHASE2","title":"Study of Efficacy, Cycle Control, and Safety of a NES-E2 Contraceptive Vaginal Ring","status":"COMPLETED","sponsor":"Premier Research","startDate":"2018-02-12","conditions":"Healthy Women, Female Contraception","enrollment":385},{"nctId":"NCT06504953","phase":"NA","title":"Evaluation of Anterior Tibial Knee Translation in Healthy Women With and Without Hormone Therapy","status":"RECRUITING","sponsor":"Centre Hospitalier Universitaire de Nice","startDate":"2024-08-01","conditions":"Women, Tibial Translation, Hormone","enrollment":90},{"nctId":"NCT03965923","phase":"PHASE3","title":"Randomized, Open Label Safety Trial of Dapivirine Vaginal Ring and Oral TRUVADA® Use in Pregnancy","status":"COMPLETED","sponsor":"National Institute of Allergy and Infectious Diseases (NIAID)","startDate":"2020-01-09","conditions":"HIV Infections","enrollment":1104},{"nctId":"NCT02367846","phase":"PHASE4","title":"Assessing the Impact of Contraceptives on Bone Health Using 41Ca","status":"ACTIVE_NOT_RECRUITING","sponsor":"Penn State University","startDate":"2015-01","conditions":"Other Disorders of Bone Development and Growth","enrollment":6},{"nctId":"NCT02432404","phase":"PHASE4","title":"Effects of a Vaginal Contraceptive Ring on Vaginal Microbiota and Local Immunity","status":"COMPLETED","sponsor":"University of Washington","startDate":"2016-03","conditions":"Bacterial Vaginosis","enrollment":81},{"nctId":"NCT06509503","phase":"PHASE4","title":"Impact of Combined Oral Contraceptive Pills on Migraine","status":"RECRUITING","sponsor":"Kafrelsheikh University","startDate":"2024-07-15","conditions":"Migraine","enrollment":400},{"nctId":"NCT01277211","phase":"PHASE3","title":"A Study to Evaluate the Effectiveness of NuvaRing® to Prevent Pregnancies in Chinese Women (P06450)","status":"COMPLETED","sponsor":"Organon and Co","startDate":"2011-09-19","conditions":"Contraception","enrollment":983},{"nctId":"NCT02668783","phase":"PHASE3","title":"Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring (MK-8342B) in Women With Primary Dysmenorrhea (With Optional Extension) (MK-8342B-059)","status":"TERMINATED","sponsor":"Organon and Co","startDate":"2016-02-11","conditions":"Moderate to Severe Primary Dysmenorrhea","enrollment":25},{"nctId":"NCT01670656","phase":"PHASE2","title":"A Study to Evaluate the Effect of Contraceptive Vaginal Rings on Primary Dysmenorrhea (P08257/MK-8175A/MK-8342B-057)","status":"COMPLETED","sponsor":"Organon and Co","startDate":"2013-01-21","conditions":"Dysmenorrhea","enrollment":439},{"nctId":"NCT02668822","phase":"PHASE3","title":"Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring (MK-8342B) in the Treatment of Women With Primary Dysmenorrhea (MK-8342B-060)","status":"TERMINATED","sponsor":"Organon and Co","startDate":"2016-02-09","conditions":"Dysmenorrhea","enrollment":18},{"nctId":"NCT01490190","phase":"PHASE4","title":"Study of the Use of a Contraceptive Vaginal Ring (NuvaRing) in Normal Daily Practice in Indian Women (P07733)","status":"COMPLETED","sponsor":"Organon and Co","startDate":"2011-12-26","conditions":"Contraception","enrollment":252},{"nctId":"NCT02524288","phase":"PHASE3","title":"Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring in Women at Risk for Pregnancy (MK-8342B-061)","status":"TERMINATED","sponsor":"Organon and Co","startDate":"2015-08-31","conditions":"Contraception","enrollment":1941},{"nctId":"NCT02616146","phase":"PHASE3","title":"Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring and Levonorgestrel-Ethinyl Estradiol Combined Oral Contraceptive in Adult Women at Risk for Pregnancy (MK-8342B-062)","status":"TERMINATED","sponsor":"Organon and Co","startDate":"2015-12-01","conditions":"Contraception","enrollment":2016},{"nctId":"NCT06250504","phase":"PHASE3","title":"Long-Acting HIV Pre-Exposure Prophylaxis Integrated With Sexual and Reproductive Health - cRCT","status":"RECRUITING","sponsor":"Africa Health Research Institute","startDate":"2024-02-27","conditions":"HIV Infections","enrollment":2000},{"nctId":"NCT04814927","phase":"PHASE4","title":"Impact of Contraceptives on Cervico-Vaginal Mucosa","status":"COMPLETED","sponsor":"Eastern Virginia Medical School","startDate":"2021-03-01","conditions":"Mucosal Inflammation, Contraceptive; Complications, Intrauterine","enrollment":112},{"nctId":"NCT04140266","phase":"PHASE3","title":"Safety and Drug Detection Study of Dapivirine Vaginal Ring and Oral TRUVADA® in Breastfeeding Mother-Infant Pairs","status":"COMPLETED","sponsor":"National Institute of Allergy and Infectious Diseases (NIAID)","startDate":"2020-09-24","conditions":"HIV Infections","enrollment":394},{"nctId":"NCT04568980","phase":"","title":"Assessment of Contraceptive Safety and Effectiveness in Cystic Fibrosis","status":"COMPLETED","sponsor":"University of Washington","startDate":"2020-09-30","conditions":"Cystic Fibrosis, Contraception","enrollment":562},{"nctId":"NCT04423068","phase":"EARLY_PHASE1","title":"Inpatient Adolescent Contraception","status":"COMPLETED","sponsor":"Children's Mercy Hospital Kansas City","startDate":"2020-12-10","conditions":"Pregnancy Related, Contraception, Contraceptive Usage","enrollment":25},{"nctId":"NCT05360550","phase":"PHASE2","title":"A Study to Evaluate the Effect of a Contraceptive Vaginal Ring LSP- 5415 on Ovarian Function in Healthy Adult Females","status":"COMPLETED","sponsor":"Lupin Research Inc","startDate":"2022-07-05","conditions":"Pregnancy Prevention","enrollment":26},{"nctId":"NCT05383924","phase":"NA","title":"Intrauterine Contraceptive Device Insertion During Cesarean Section (CS) Versus Delayed Insertion","status":"COMPLETED","sponsor":"Ain Shams Maternity Hospital","startDate":"2021-05-01","conditions":"Contraception, IUD","enrollment":80},{"nctId":"NCT03598088","phase":"NA","title":"Safety and Acceptability Study of a Non-Hormonal Ring","status":"COMPLETED","sponsor":"Daré Bioscience, Inc.","startDate":"2018-05-23","conditions":"Contraception","enrollment":38},{"nctId":"NCT05252117","phase":"PHASE4","title":"Uterovaginal Plexus Block With Articaine for Intrauterine Device Placement Patients Who Are Indicated for the Use of Copper IUD as a Contraceptive Method Will be Invited to Participate in This Research.","status":"UNKNOWN","sponsor":"Universidade do Vale do Sapucai","startDate":"2021-02-01","conditions":"Contraception, IUD, Anesthesia, Local","enrollment":240},{"nctId":"NCT04537078","phase":"PHASE3","title":"Progestin Primed Double Stimulation Protocol Versus Flexible GnRH Antagonist Protocol in Poor Responders","status":"COMPLETED","sponsor":"El Shatby University Hospital for Obstetrics and Gynecology","startDate":"2020-09-01","conditions":"Infertility, Female","enrollment":90},{"nctId":"NCT01044056","phase":"PHASE4","title":"A Trial in Healthy Female Subjects to Compare the Pharmacokinetics of Ethinyl Estradiol of NuvaRing®, a Contraceptive Patch (EVRA(TM)) and an Oral Contraceptive (Microgynon® 30) (Study 34237 (P06650)) (COMPLETED)","status":"COMPLETED","sponsor":"Organon and Co","startDate":"2004-03","conditions":"Contraception","enrollment":24},{"nctId":"NCT02403401","phase":"PHASE3","title":"Safety and Contraceptive Efficacy of an Intravaginal Ring With LNG (Levonorgestrel) Over One Year in Healthy Women","status":"COMPLETED","sponsor":"Bayer","startDate":"2015-05-15","conditions":"Contraception","enrollment":1471},{"nctId":"NCT01058252","phase":"","title":"Minimal Stimulation Protocol Using Aromek(Letrozole) and Follitrope(recFSH) Combined With INVOCell-Low Cost IVF","status":"UNKNOWN","sponsor":"Galaxy Pharma (Pvt) Limited","startDate":"2021-05","conditions":"Primary Infertility, Secondary Infertility, Low Responders","enrollment":30},{"nctId":"NCT00635570","phase":"PHASE4","title":"Acceptability of the NuvaRing Among Students","status":"COMPLETED","sponsor":"University of Chicago","startDate":"2008-07","conditions":"Birth Control Compliance","enrollment":273},{"nctId":"NCT04290390","phase":"PHASE1","title":"Annovera™ Drug-Drug Interaction Study","status":"COMPLETED","sponsor":"TherapeuticsMD","startDate":"2020-02-12","conditions":"Women, Contraception","enrollment":67},{"nctId":"NCT02367833","phase":"PHASE4","title":"Effects of Oral vs. Non-oral Contraceptives on the GH/IGF-1 Axis","status":"COMPLETED","sponsor":"Penn State University","startDate":"2015-01","conditions":"Bone; Disorder, Development and Growth","enrollment":60},{"nctId":"NCT02404038","phase":"NA","title":"A Study to Evaluate the Acceptability and Preference for Contraceptive Options as Proxy for HIV Prevention Methods","status":"UNKNOWN","sponsor":"Desmond Tutu HIV Centre","startDate":"2015-07","conditions":"HIV","enrollment":131},{"nctId":"NCT02445989","phase":"PHASE4","title":"Effects of Contraceptive Ring on Vaginal Microbiota, HIV Shedding and Local Immunity","status":"COMPLETED","sponsor":"University of Washington","startDate":"2016-05","conditions":"Bacterial Vaginosis, HIV","enrollment":120},{"nctId":"NCT01903031","phase":"PHASE2","title":"Evaluating Pharmacokinetic Interactions With Vaginal Ring Contraceptives and ART","status":"COMPLETED","sponsor":"Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections","startDate":"2014-12-30","conditions":"HIV-1 Infection","enrollment":84},{"nctId":"NCT01755741","phase":"PHASE1","title":"Functionality of Male Condoms With a Silicone Elastomer Vaginal RIng","status":"COMPLETED","sponsor":"International Partnership for Microbicides, Inc.","startDate":"2013-02","conditions":"Human Immunodeficiency Virus","enrollment":70},{"nctId":"NCT00263341","phase":"PHASE3","title":"Safety and Efficacy of a Contraceptive Vaginal Ring Delivering Nestorone® and Ethinyl Estradiol","status":"COMPLETED","sponsor":"Population Council","startDate":"2005-12","conditions":"Contraception","enrollment":1135},{"nctId":"NCT01755754","phase":"PHASE1","title":"A Trial to Assess the Functionality of Female Condom With a Silicone Elastomer Vaginal Ring","status":"COMPLETED","sponsor":"International Partnership for Microbicides, Inc.","startDate":"2013-08","conditions":"Human Immunodeficiency Virus","enrollment":160},{"nctId":"NCT03074786","phase":"PHASE2","title":"Reversing the Epidemic in Africa With Choices in HIV Prevention (REACH)","status":"WITHDRAWN","sponsor":"International Partnership for Microbicides, Inc.","startDate":"2017-11","conditions":"HIV-1-infection","enrollment":""},{"nctId":"NCT02626208","phase":"PHASE2","title":"Dose Finding Study of Contraceptive Vaginal Ring With Different Estradiol Levels in Combination With Nestorone","status":"COMPLETED","sponsor":"Premier Research","startDate":"2016-01","conditions":"Suppression of Ovulation","enrollment":65},{"nctId":"NCT00791297","phase":"PHASE2","title":"Study to Evaluate the Safety and Efficacy of Two Contraceptive Vaginal Rings Delivering a Daily Dose of 1500 or 2500 μg of CDB-2914","status":"COMPLETED","sponsor":"Population Council","startDate":"2008-10","conditions":"Contraception","enrollment":55},{"nctId":"NCT02215395","phase":"PHASE1","title":"An Open-label Study to Evaluate the Effects of Concurrent Administration of Vaginal Antimycotic Medication Miconazole Nitrate on the Pharmacokinetics of Nestorone and Ethinyl Estradiol Delivered by a Contraceptive Vaginal Ring in Normal Ovulating Women","status":"COMPLETED","sponsor":"Population Council","startDate":"2014-03","conditions":"Antifungal Drug Adverse Reaction","enrollment":45},{"nctId":"NCT02451826","phase":"PHASE1, PHASE2","title":"A Study to Evaluate the Effect of a Contraceptive Vaginal Ring Delivering Ulipristal Acetate Combined With a Single or Repeated Levonorgestrel on Inhibition of Ovulation, Endometrial Changes and Bleeding Patterns in Normal Cycling Women","status":"UNKNOWN","sponsor":"Population Council","startDate":"2015-05","conditions":"Ovulation Inhibition","enrollment":19},{"nctId":"NCT00213096","phase":"PHASE2","title":"Effects of Hormonal Contraceptives on Liver Proteins and Coagulation Factors: A Comparison of a Contraceptive Vaginal Ring and an Oral Contraceptive","status":"COMPLETED","sponsor":"Population Council","startDate":"2003-03","conditions":"Contraception","enrollment":50},{"nctId":"NCT03120728","phase":"PHASE4","title":"Application for the Etonogestrel/Ethinyl Estradiol Ring","status":"UNKNOWN","sponsor":"University of Southern California","startDate":"2017-07-10","conditions":"Emergency Contraception, Healthy, Reproductive Age Women","enrollment":36},{"nctId":"NCT01546454","phase":"NA","title":"Relationship Between the Menstrual Cycle and Heart Disease in Women","status":"COMPLETED","sponsor":"Oregon Health and Science University","startDate":"2012-02","conditions":"Coronary Heart Disease","enrollment":5},{"nctId":"NCT00369967","phase":"NA","title":"Quick Start Initiation of the Contraceptive Vaginal Ring in Adolescents","status":"TERMINATED","sponsor":"Virginia Commonwealth University","startDate":"2007-02","conditions":"Contraception Desired","enrollment":48},{"nctId":"NCT02312726","phase":"","title":"Postplacental Intrauterine Device Insertion: A Mixed Methods Assessment of Women's Experience","status":"COMPLETED","sponsor":"University of New Mexico","startDate":"2013-11","conditions":"Contraception","enrollment":135},{"nctId":"NCT00928538","phase":"PHASE4","title":"Nurse Family Partnership (NFP) Contraceptive Study","status":"COMPLETED","sponsor":"Oregon Health and Science University","startDate":"2009-09","conditions":"Pregnancy, Effective Contraceptive Use, Family Planning","enrollment":344},{"nctId":"NCT02529683","phase":"NA","title":"Study of Nuvaring Acceptability, Adherence and Biological Effects Among HIV-negative Women in Kenya","status":"COMPLETED","sponsor":"Centers for Disease Control and Prevention","startDate":"2014-04","conditions":"Hormonal Contraception","enrollment":200},{"nctId":"NCT01638767","phase":"PHASE4","title":"NuvaRing Versus Marvelon in the Coordination of In Vitro Fertilization Cycles","status":"TERMINATED","sponsor":"Clinique Ovo","startDate":"2012-07","conditions":"Infertility","enrollment":7},{"nctId":"NCT01813162","phase":"PHASE1","title":"In Vivo Drug Interaction Pharmacokinetic Study of Tenofovir 1% Gel and Three Commonly Used Vaginal Products","status":"COMPLETED","sponsor":"CONRAD","startDate":"2013-12","conditions":"HIV Prevention","enrollment":101},{"nctId":"NCT01421368","phase":"PHASE1","title":"Contraception and Menstrual Cycle Effect on Pharmacokinetics, Pharmacodynamics and Safety in Tenofovir Vaginal Gel Use","status":"COMPLETED","sponsor":"CONRAD","startDate":"2012-03","conditions":"HIV Prevention","enrollment":72},{"nctId":"NCT01796613","phase":"PHASE2, PHASE3","title":"Safety and Acceptability of Vaginal Rings That Protect Women From Unintended Pregnancy","status":"COMPLETED","sponsor":"Institute of Tropical Medicine, Belgium","startDate":"2013-06","conditions":"Contraception","enrollment":120},{"nctId":"NCT00524771","phase":"","title":"Transatlantic Active Surveillance on Cardiovascular Safety of NuvaRing (TASC)","status":"COMPLETED","sponsor":"Center for Epidemiology and Health Research, Germany","startDate":"2007-09","conditions":"Contraception","enrollment":34100},{"nctId":"NCT00999479","phase":"NA","title":"Post Operative Continuous Active Combination Sex Steroids for the Prevention of Recurrent Endometrioma Formation","status":"WITHDRAWN","sponsor":"University of Oklahoma","startDate":"2009-10","conditions":"Endometrioma","enrollment":""},{"nctId":"NCT01588873","phase":"PHASE4","title":"Contraceptive Pill and Hormonal Vaginal Ring in Women With Polycystic Ovary Syndrome","status":"UNKNOWN","sponsor":"University of Oulu","startDate":"2012-04","conditions":"Adverse Effect of Oral Contraceptives, Sequela","enrollment":42},{"nctId":"NCT01448291","phase":"PHASE4","title":"Effect of the Etonogestrel 0.12mg/Ethinyl Estradiol 0.015mg Vaginal Ring on Vaginal Innate and Inflammatory Biomarkers","status":"UNKNOWN","sponsor":"Eastern Virginia Medical School","startDate":"2011-10","conditions":"Vaginosis, Bacterial","enrollment":30},{"nctId":"NCT01087879","phase":"NA","title":"The Effect of Hormonal Contraceptives on Androgens and Glucose Metabolism","status":"COMPLETED","sponsor":"University of Oulu","startDate":"2007-10","conditions":"Contraception","enrollment":45},{"nctId":"NCT01384331","phase":"PHASE4","title":"New Treatments for Troublesome Bleeding in Implanon Users","status":"UNKNOWN","sponsor":"Family Planning Association New South Wales","startDate":"2011-07","conditions":"Menstrual Problem","enrollment":200},{"nctId":"NCT01266759","phase":"NA","title":"Efficacy of Combined Contraceptive Vaginal Ring(NuvaRing)in Women With Idiopathic Menorrhagia","status":"COMPLETED","sponsor":"Mansoura University","startDate":"2008-07","conditions":"Menorrhagia","enrollment":95},{"nctId":"NCT00565240","phase":"NA","title":"Mid-luteal Phase Synchronization of Ovarian Folliculogenesis in Women","status":"COMPLETED","sponsor":"University of Saskatchewan","startDate":"2007-11","conditions":"Ovarian Follicle","enrollment":41},{"nctId":"NCT00475553","phase":"NA","title":"Management of Breakthrough Bleeding During Extended Therapy Use With NuvaRing®","status":"COMPLETED","sponsor":"Scott and White Hospital & Clinic","startDate":"2006-05","conditions":"Breakthrough Bleeding, Breakthrough Spotting","enrollment":75},{"nctId":"NCT00332995","phase":"PHASE1","title":"Safety and Feasibility Study of Dapivirine (TMC120) Vaginal Ring in Belgium","status":"COMPLETED","sponsor":"International Partnership for Microbicides, Inc.","startDate":"2005-07","conditions":"HIV Infections","enrollment":13},{"nctId":"NCT00700284","phase":"PHASE1","title":"Feasibility Study of a Vaginal Ring for Delivery of TMC120 (Dapivirine)","status":"COMPLETED","sponsor":"International Partnership for Microbicides, Inc.","startDate":"2004-10","conditions":"HIV Infections","enrollment":12},{"nctId":"NCT00269620","phase":"PHASE4","title":"PARIS or PAtch RIng Study: A Trial to Evaluate NuvaRing Versus OrthoEvra","status":"COMPLETED","sponsor":"University of Pittsburgh","startDate":"2005-06","conditions":"Contraception","enrollment":500},{"nctId":"NCT00520455","phase":"NA","title":"Randomized Trial of Advanced Provision Emergency Contraception Among Women With Gonorrhea or Chlamydia","status":"COMPLETED","sponsor":"University of Washington","startDate":"2004-01","conditions":"Pregnancy","enrollment":177},{"nctId":"NCT00357526","phase":"NA","title":"Oral Contraceptive Pills Compared to Vaginal Rings","status":"COMPLETED","sponsor":"University of California, San Francisco","startDate":"2003-04","conditions":"Pregnancy","enrollment":130},{"nctId":"NCT00065871","phase":"NA","title":"The Direct Access Study: Access to Hormonal Birth Control Through Community Pharmacies","status":"UNKNOWN","sponsor":"Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)","startDate":"2003-06","conditions":"Contraception","enrollment":250}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":228,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Nuva Ring"],"phase":"marketed","status":"active","brandName":"Contraceptive Vaginal Ring","genericName":"Contraceptive Vaginal Ring","companyName":"Penn State University","companyId":"penn-state-university","modality":"Small molecule","firstApprovalDate":"","aiSummary":"The Contraceptive Vaginal Ring is a small molecule contraceptive device that has been studied for various conditions, including HIV infections, breakthrough bleeding, and polycystic ovary syndrome. The ring's mechanism of action is not specified in the provided information, but it is classified as a small molecule modality.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}