{"id":"combizym-bifidobacteri","safety":{"commonSideEffects":[{"rate":null,"effect":"Gastrointestinal upset"},{"rate":null,"effect":"Mild abdominal discomfort"},{"rate":null,"effect":"Allergic reactions (rare)"}]},"_chembl":{"chemblId":"CHEMBL2108073","moleculeType":"Unknown"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Combizym supplies pancreatic enzymes (amylase, protease, lipase) to aid digestion of carbohydrates, proteins, and fats. Bifidobacteria are beneficial probiotics that colonize the intestinal tract, promote healthy microbiota balance, and support digestive and immune function. Together, they work to enhance nutrient absorption and gastrointestinal health.","oneSentence":"Combizym + Bifidobacteri is a combination product that provides digestive enzymes and beneficial bifidobacteria to improve gastrointestinal function and restore healthy gut microbiota.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T00:30:34.566Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Digestive enzyme deficiency and gastrointestinal dysfunction"},{"name":"Dysbiosis and microbiota imbalance"}]},"trialDetails":[{"nctId":"NCT02097394","phase":"PHASE4","title":"The Clinical Study on Combizym and Bifidobacteri to Prevent the Recurrence of Colon Polyps","status":"UNKNOWN","sponsor":"RenJi Hospital","startDate":"2013-06","conditions":"Combizym, Bifidobacteri, Colon Polyps","enrollment":200}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Combizym(Oryz-Aspergillus Enzyme And Pancreatin Tablet)","(produced by Nordmark Arzneimittel GmbH & Co. KG)","Bifidobacteri(Live Combined Bifidobacterium，Lactobac and Enterococcus Capsules)","(produced by Shanghai XinYi Company)"],"phase":"marketed","status":"active","brandName":"Combizym + Bifidobacteri","genericName":"Combizym + Bifidobacteri","companyName":"RenJi Hospital","companyId":"renji-hospital","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Combizym + Bifidobacteri is a combination product that provides digestive enzymes and beneficial bifidobacteria to improve gastrointestinal function and restore healthy gut microbiota. Used for Digestive enzyme deficiency and gastrointestinal dysfunction, Dysbiosis and microbiota imbalance.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}