{"id":"combination-fish-oil-and-borage-seed-oil","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Nausea"},{"rate":"5-10%","effect":"Diarrhea"},{"rate":"5-10%","effect":"Abdominal pain"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"Fish oil is rich in omega-3 fatty acids, particularly EPA and DHA, which have anti-inflammatory properties and may help lower triglycerides and blood pressure. Borage seed oil is a rich source of gamma-linolenic acid (GLA), an omega-6 fatty acid that may help reduce inflammation and improve skin health.","oneSentence":"Combination fish oil and borage seed oil may help reduce inflammation and improve heart health by modulating the body's response to omega-6 and omega-3 fatty acids.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:06:43.119Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Hypertriglyceridemia"},{"name":"Cardiovascular disease prevention"}]},"trialDetails":[{"nctId":"NCT02350595","phase":"NA","title":"A Study on the Possible Health Effects of Lean Fish and Fatty Fish Intake in Overweight or Obese Adults","status":"COMPLETED","sponsor":"University of Bergen","startDate":"2011-08","conditions":"Overweight, Obesity","enrollment":76},{"nctId":"NCT03141931","phase":"NA","title":"The Effects of Dietary Supplementation With Omega-3 Fatty Acids on Symptoms of Dry Eye","status":"COMPLETED","sponsor":"The University of New South Wales","startDate":"2017-08-21","conditions":"Dry Eye","enrollment":119},{"nctId":"NCT03842514","phase":"NA","title":"Food Additives - Do Processed Diets Impact on Gut and Metabolic Health","status":"COMPLETED","sponsor":"University of Aberdeen","startDate":"2019-05-01","conditions":"Gut Health, Metabolic Health","enrollment":20},{"nctId":"NCT01145066","phase":"PHASE2","title":"Botanical Oil Supplementation in Diabetic and Metabolic Syndrome Subjects","status":"COMPLETED","sponsor":"Wake Forest University Health Sciences","startDate":"2009-05","conditions":"Diabetes, Metabolic Syndrome x","enrollment":80},{"nctId":"NCT02130908","phase":"NA","title":"A Study on the Possible Health Effects of Lean Fish, Fatty Fish and Lean Meat Intake in Non-obese Adults","status":"COMPLETED","sponsor":"University of Bergen","startDate":"2011-03","conditions":"Metabolic Disorders, Obesity","enrollment":45},{"nctId":"NCT01768429","phase":"NA","title":"The Effect of n-3 Fatty Acids and Fish on Glucose and Lipid Metabolism in Subjects With Impaired Glucose Metabolism","status":"COMPLETED","sponsor":"University of Eastern Finland","startDate":"2012-10","conditions":"Hyperglycemia","enrollment":79},{"nctId":"NCT00072982","phase":"PHASE3","title":"Treatment of Rheumatoid Arthritis With Marine and Botanical Oils","status":"UNKNOWN","sponsor":"National Center for Complementary and Integrative Health (NCCIH)","startDate":"2006-11","conditions":"Rheumatoid Arthritis","enrollment":156}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":5,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["EPA and GLA"],"phase":"phase_3","status":"active","brandName":"combination fish oil and borage seed oil","genericName":"combination fish oil and borage seed oil","companyName":"National Center for Complementary and Integrative Health (NCCIH)","companyId":"national-center-for-complementary-and-integrative-health-nccih","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Combination fish oil and borage seed oil may help reduce inflammation and improve heart health by modulating the body's response to omega-6 and omega-3 fatty acids. Used for Hypertriglyceridemia, Cardiovascular disease prevention.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}