{"id":"cocos-nucifera-whole","safety":{"commonSideEffects":[]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Coconut contains medium-chain triglycerides (MCTs), electrolytes, polyphenols, and other phytochemicals that may influence lipid metabolism, provide antimicrobial properties, and support cellular health. The whole plant formulation likely leverages multiple bioactive constituents rather than a single molecular target, consistent with traditional and ethnobotanical use.","oneSentence":"Cocos nucifera (coconut) whole plant extract provides nutritional and bioactive compounds that may support metabolic health and immune function.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T00:45:07.030Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Phase 3 indication not publicly specified; likely metabolic or nutritional support based on coconut composition"}]},"trialDetails":[{"nctId":"NCT05681468","phase":"NA","title":"Metabolic and Inflammatory Outcomes of the Ketogenic Diet Comparing Saturated and Unsaturated Fat Sources","status":"RECRUITING","sponsor":"University of Alberta","startDate":"2023-09-18","conditions":"PreDiabetes, Diabetes Mellitus, Type 2, Overweight and Obesity","enrollment":175},{"nctId":"NCT07308483","phase":"NA","title":"Ketogenic Approach to Restore Muscle in Older Patients With Community-Acquired Pneumonia - KARMA-P Trial","status":"NOT_YET_RECRUITING","sponsor":"University of Alabama at Birmingham","startDate":"2026-06-01","conditions":"Pneumonia","enrollment":30},{"nctId":"NCT07188272","phase":"NA","title":"Effect of High-intensity Interval Training Combined With DASH Diet on Arterial Stiffness in Hypertensive Patients","status":"RECRUITING","sponsor":"Deraya University","startDate":"2025-07-10","conditions":"Hypertension, Arterial Stiffness","enrollment":20},{"nctId":"NCT05268042","phase":"NA","title":"Moderately Carbohydrate-restricted Diet to Treat NAFLD in Adolescents","status":"RECRUITING","sponsor":"University of Alabama at Birmingham","startDate":"2022-05-01","conditions":"Non-Alcoholic Fatty Liver Disease, Obesity","enrollment":80},{"nctId":"NCT06075914","phase":"NA","title":"Ketone Conferred Resiliency Against Sleep Restriction With Nutritional Intervention.","status":"RECRUITING","sponsor":"Ohio State University","startDate":"2023-05-01","conditions":"Sleep Deprivation, Nutritional Intervention","enrollment":60},{"nctId":"NCT03430310","phase":"NA","title":"Return of First-phase Insulin Secretion in Type 2 Diabetes is Associated With Depletion of Pancreas Lipid","status":"COMPLETED","sponsor":"University of Alabama at Birmingham","startDate":"2018-10-09","conditions":"Type 2 Diabetes Mellitus","enrollment":65},{"nctId":"NCT06610812","phase":"NA","title":"\"KETOGENIC MEDITERRANEAN VERSUS HYPOCALORIC BALANCED DIET ON POLYCYSTIC OVARIAN ADOLESCENTS\"","status":"COMPLETED","sponsor":"MTI University","startDate":"2021-11-01","conditions":"Polycystic Ovary Disease","enrollment":40},{"nctId":"NCT04272749","phase":"NA","title":"Consumer Perceptions of Milk Beverages","status":"COMPLETED","sponsor":"Clinical Nutrition Research Center, Illinois Institute of Technology","startDate":"2019-12-16","conditions":"Consumer Behavior","enrollment":100},{"nctId":"NCT06296862","phase":"NA","title":"Effect of DASH on HF Outcomes Heart Failure Status in Older Adults (DASH HF)","status":"UNKNOWN","sponsor":"University of Georgia","startDate":"2024-03","conditions":"Heart Failure","enrollment":38},{"nctId":"NCT03810378","phase":"NA","title":"Contrasting Ketogenic and Mediterranean Diets in Individuals With Type 2 Diabetes and Prediabetes: The Keto-Med Trial","status":"COMPLETED","sponsor":"Stanford University","startDate":"2019-06-05","conditions":"Diabetes Mellitus, Type 2, PreDiabetes","enrollment":61},{"nctId":"NCT04972747","phase":"NA","title":"The Effect of Skin Care Applied With Two Different Oils on Skin Integrity and Growth Parameters in Premature Babies","status":"UNKNOWN","sponsor":"Derince Training and Research Hospital","startDate":"2020-10-16","conditions":"Premature Birth, Skin Care","enrollment":72},{"nctId":"NCT04078971","phase":"NA","title":"Effects of Ketogenic Diet on Body Composition and Performance in Soccer Players","status":"COMPLETED","sponsor":"Antonio Paoli","startDate":"2018-05-02","conditions":"Athletic Performance","enrollment":16},{"nctId":"NCT03785808","phase":"NA","title":"Reducing Insulin, Growth Hormones, and Tumors","status":"TERMINATED","sponsor":"Fred Hutchinson Cancer Center","startDate":"2018-12-21","conditions":"Diet Modification, Lung Cancer","enrollment":3},{"nctId":"NCT03617068","phase":"PHASE3","title":"The Effectiveness of Coconut Oil Cream as a Prevention Treatment for Occupational Hand Dermatitis Among Batik Workers","status":"COMPLETED","sponsor":"Fakultas Kedokteran Universitas Indonesia","startDate":"2017-02-06","conditions":"Hand Dermatoses","enrollment":32},{"nctId":"NCT03538990","phase":"NA","title":"Effect of DASH Eating Pattern on Heart Failure Outcomes","status":"UNKNOWN","sponsor":"University of Georgia","startDate":"2018-11-15","conditions":"Heart Failure NYHA Class III","enrollment":36},{"nctId":"NCT01759667","phase":"NA","title":"DIT After RYGB - A Prospective Study","status":"COMPLETED","sponsor":"Silvia Leite Faria","startDate":"2012-08","conditions":"Obesity, Morbid Obesity, Bariatric Surgery","enrollment":13}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Coconut Oil Cream"],"phase":"phase_3","status":"active","brandName":"Cocos Nucifera Whole","genericName":"Cocos Nucifera Whole","companyName":"Fakultas Kedokteran Universitas Indonesia","companyId":"fakultas-kedokteran-universitas-indonesia","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Cocos nucifera (coconut) whole plant extract provides nutritional and bioactive compounds that may support metabolic health and immune function. Used for Phase 3 indication not publicly specified; likely metabolic or nutritional support based on coconut composition.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":true,"score":3}}