{"id":"cls006-vehicle","safety":{"commonSideEffects":[]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"As a vehicle formulation rather than an active pharmaceutical ingredient, CLS006 Vehicle serves as the carrier system for topical drugs, optimizing their absorption and bioavailability at the site of application. The specific composition and mechanism depend on the active drug being delivered, but the vehicle itself is engineered to improve stability, spreadability, and transdermal or transepidermal penetration.","oneSentence":"CLS006 Vehicle is a topical formulation vehicle designed to enhance drug delivery and penetration through the skin.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:06:28.103Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Vehicle formulation for topical dermatological agents (specific indication depends on active drug)"}]},"trialDetails":[{"nctId":"NCT03259620","phase":"PHASE3","title":"A Study to Evaluate the Safety and Efficacy of CLS006 Versus Vehicle in Subjects 2 Years of Age or Older With Cutaneous Common Warts","status":"COMPLETED","sponsor":"Maruho Co., Ltd.","startDate":"2017-10-30","conditions":"Cutaneous Common Warts","enrollment":491},{"nctId":"NCT02971891","phase":"PHASE3","title":"A Phase 3 Study to Evaluate the Efficacy and Safety of CLS006 Versus Vehicle in Subjects 2 Years of Age or Older With Cutaneous Common Warts","status":"COMPLETED","sponsor":"Maruho Co., Ltd.","startDate":"2017-01","conditions":"Cutaneous Common Warts","enrollment":484}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":152993,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"CLS006 Vehicle","genericName":"CLS006 Vehicle","companyName":"Maruho Co., Ltd.","companyId":"maruho-co-ltd","modality":"Small molecule","firstApprovalDate":"","aiSummary":"CLS006 Vehicle is a topical formulation vehicle designed to enhance drug delivery and penetration through the skin. Used for Vehicle formulation for topical dermatological agents (specific indication depends on active drug).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":true,"score":3}}