{"id":"cloxotestosterone","rwe":[],"tags":[{"label":"Androgen","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Androgens","category":"pharmacology"},{"label":"Hormones","category":"pharmacology"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":["cloxotestosterone"],"offLabel":[],"synonyms":["cloxotestosterone"],"timeline":[],"approvals":[],"ecosystem":[],"mechanism":{"moaClass":"Androgen Receptor Agonists","modality":"Small Molecule","drugClass":"Androgen","explanation":"Imagine your body has locks on cells that only male hormones can open. Cloxotestosterone is a key that fits into these locks, allowing it to influence the activity of cells and tissues that respond to male hormones.","oneSentence":"Cloxotestosterone works by binding to androgen receptors in the body, mimicking the effects of natural male hormones.","technicalDetail":"Cloxotestosterone exerts its effects by binding to androgen receptors (AR), a type of nuclear receptor that regulates gene expression in response to androgens such as testosterone and dihydrotestosterone (DHT). This binding causes a conformational change in the AR, leading to the recruitment of coactivator proteins and the transcription of androgen-responsive genes."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3113","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=CLOXOTESTOSTERONE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T10:14:47.773791","biosimilars":[],"competitors":[],"genericName":"cloxotestosterone","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"MMSL":"2966","NDDF":"001245","UNII":"8422DH508N","CHEBI":"CHEBI:17347","VANDF":"4017484","INN_ID":"1305","RXNORM":"10379","UMLSCUI":"C2699389","ChEMBL_ID":"CHEMBL2106514","DRUGBANK_ID":"DB00624","PDB_CHEM_ID":" TES","PUBCHEM_CID":"20055048","SNOMEDCT_US":"109033004","MESH_DESCRIPTOR_UI":"D013739"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":0,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","brandName":"CLOXOTESTOSTERONE","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Cloxotestosterone is a synthetic androgen, a small molecule drug belonging to the androgen class. Its original development and current ownership are unknown. The target and approved indications of Cloxotestosterone are also not specified. It is not known whether Cloxotestosterone is FDA-approved or off-patent. Further information on its commercial status and key safety considerations is required.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}