{"id":"cloranolol","rwe":[{"pmid":"7663288","year":"1995","title":"[The effect of beta-adrenoblockaders on the elasticity of the vessels of the greater circulation].","finding":"","journal":"Eksperimental'naia i klinicheskaia farmakologiia","studyType":"Clinical Study"},{"pmid":"2571334","year":"1989","title":"Action of beta-adrenoceptor blockers on liver function of rats.","finding":"","journal":"Arzneimittel-Forschung","studyType":"Clinical Study"}],"tags":[{"label":"cloranolol","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"C07AA27","category":"atc"},{"label":"Active","category":"status"},{"label":"Adrenergic Agents","category":"pharmacology"},{"label":"Adrenergic Antagonists","category":"pharmacology"},{"label":"Adrenergic beta-Antagonists","category":"pharmacology"},{"label":"Antihypertensive Agents","category":"pharmacology"},{"label":"Cardiovascular Agents","category":"pharmacology"},{"label":"Neurotransmitter Agents","category":"pharmacology"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"tobanum","offLabel":[],"synonyms":["cloranolol","chloranolol","tobanum"],"timeline":[],"approvals":[],"brandName":"Tobanum","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"cloranolol","explanation":"Unfortunately, the exact mechanism of action of Tobanum is not well understood, but it is thought to involve the modulation of a particular cellular pathway to produce a desired outcome.","oneSentence":"Tobanum works by interacting with a specific target in the body to produce a therapeutic effect.","technicalDetail":"The technical details of Tobanum's mechanism of action are not well established, but it is believed to involve the inhibition of a specific enzyme or receptor, leading to a cascade of downstream effects that ultimately produce its therapeutic effects."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/710","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=CLORANOLOL","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T10:13:23.134955","biosimilars":[],"competitors":[{"drugName":"oxprenolol","drugSlug":"oxprenolol","fdaApproval":"","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"pindolol","drugSlug":"pindolol","fdaApproval":"1982-09-03","genericCount":11,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"propranolol","drugSlug":"propranolol","fdaApproval":"1967-11-13","patentExpiry":"Oct 16, 2028","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"timolol","drugSlug":"timolol","fdaApproval":"1978-08-17","genericCount":2,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"sotalol","drugSlug":"sotalol","fdaApproval":"1992-10-30","patentExpiry":"Nov 19, 2034","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"nadolol","drugSlug":"nadolol","fdaApproval":"1979-12-10","genericCount":13,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"carteolol","drugSlug":"carteolol","fdaApproval":"1988-12-28","genericCount":3,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"penbutolol","drugSlug":"penbutolol","fdaApproval":"1987-12-30","patentStatus":"Unknown","relationship":"same-class"}],"genericName":"cloranolol","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"oxprenolol","brandName":"oxprenolol","genericName":"oxprenolol","approvalYear":"","relationship":"same-class"},{"drugId":"pindolol","brandName":"pindolol","genericName":"pindolol","approvalYear":"1982","relationship":"same-class"},{"drugId":"propranolol","brandName":"propranolol","genericName":"propranolol","approvalYear":"1967","relationship":"same-class"},{"drugId":"timolol","brandName":"timolol","genericName":"timolol","approvalYear":"1978","relationship":"same-class"},{"drugId":"sotalol","brandName":"sotalol","genericName":"sotalol","approvalYear":"1992","relationship":"same-class"},{"drugId":"nadolol","brandName":"nadolol","genericName":"nadolol","approvalYear":"1979","relationship":"same-class"},{"drugId":"carteolol","brandName":"carteolol","genericName":"carteolol","approvalYear":"1988","relationship":"same-class"},{"drugId":"penbutolol","brandName":"penbutolol","genericName":"penbutolol","approvalYear":"1987","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"Q3U058H86V","CHEBI":"CHEBI:135217","INN_ID":"4646","UMLSCUI":"C0076772","ChEMBL_ID":"CHEMBL156791","KEGG_DRUG":"D07183","DRUGBANK_ID":"DB13508","PUBCHEM_CID":"65814","MESH_SUPPLEMENTAL_RECORD_UI":"C025725"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":2,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"C07AA27","allCodes":["C07AA27"]},"biosimilarFilings":[],"recentPublications":[{"date":"1995 May-Jun","pmid":"7663288","title":"[The effect of beta-adrenoblockaders on the elasticity of the vessels of the greater circulation].","journal":"Eksperimental'naia i klinicheskaia farmakologiia"},{"date":"1989 Jul","pmid":"2571334","title":"Action of beta-adrenoceptor blockers on liver function of rats.","journal":"Arzneimittel-Forschung"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Tobanum (CLORANOLOL) is a small molecule drug in the cloranolol class, but its target and exact mechanism of action are unknown. It is not clear if it is FDA-approved or commercially available. There is limited information available on its pharmacokinetic properties, such as half-life and bioavailability. Tobanum is not listed as an off-patent or generic medication. Further research is needed to understand its clinical applications and safety profile.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}