{"id":"clometocillin","rwe":[{"pmid":"9578165","year":"1998","title":"In-vitro activity of 21 beta-lactam antibiotics against penicillin-susceptible and penicillin-resistant Streptococcus pneumoniae.","finding":"","journal":"The Journal of antimicrobial chemotherapy","studyType":"Clinical Study"},{"pmid":"14145726","year":"1964","title":"[USE IN CHILDREN OF A NEW ORAL PENICILLIN: CLOMETOCILLIN].","finding":"","journal":"Gazette medicale de France","studyType":"Clinical Study"}],"tags":[{"label":"clometocillin","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"J01CE07","category":"atc"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"clometacillin","offLabel":[],"synonyms":["clometocillin","clometacillin","clomethacillin","clomethocillin","clometicillin","DL-Clometocillin"],"timeline":[],"approvals":[],"brandName":"Clometacillin","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"clometocillin","explanation":"Imagine your body's cells have locks on them, and each lock has a specific key that fits perfectly. Clometacillin is like a key that binds to a specific lock, but we don't know which lock it is or what it does when it binds. This binding can affect how cells work, but we need more research to understand the details.","oneSentence":"Clometacillin works by binding to a specific target, although its exact mechanism of action is unknown.","technicalDetail":"Clometacillin is a small molecule that interacts with a specific molecular target, although the exact nature of this interaction is currently unknown."},"_wikipedia":{"url":"https://en.wikipedia.org/wiki/Clometocillin","title":"Clometocillin","extract":"Clometocillin is a penicillin."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/699","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=CLOMETOCILLIN","fields":["publications"],"source":"PubMed/NCBI"},{"id":3,"url":"https://en.wikipedia.org/wiki/Clometocillin","fields":["history","overview"],"source":"Wikipedia"}],"_enrichedAt":"2026-03-30T10:12:19.643167","biosimilars":[],"competitors":[{"drugName":"benzylpenicillin","drugSlug":"benzylpenicillin","fdaApproval":"1947-02-06","relationship":"same-class"},{"drugName":"phenoxymethylpenicillin","drugSlug":"phenoxymethylpenicillin","fdaApproval":"1958-01-13","relationship":"same-class"},{"drugName":"benzathine benzylpenicillin","drugSlug":"benzathine-benzylpenicillin","fdaApproval":"1952-06-27","relationship":"same-class"},{"drugName":"procaine benzylpenicillin","drugSlug":"procaine-benzylpenicillin","fdaApproval":"1948-04-26","relationship":"same-class"}],"genericName":"clometocillin","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"benzylpenicillin","brandName":"benzylpenicillin","genericName":"benzylpenicillin","approvalYear":"1947","relationship":"same-class"},{"drugId":"phenoxymethylpenicillin","brandName":"phenoxymethylpenicillin","genericName":"phenoxymethylpenicillin","approvalYear":"1958","relationship":"same-class"},{"drugId":"benzathine-benzylpenicillin","brandName":"benzathine benzylpenicillin","genericName":"benzathine benzylpenicillin","approvalYear":"1952","relationship":"same-class"},{"drugId":"procaine-benzylpenicillin","brandName":"procaine benzylpenicillin","genericName":"procaine benzylpenicillin","approvalYear":"1948","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"YI8LL014GF","CHEBI":"CHEBI:131732","INN_ID":"1326","UMLSCUI":"C0055921","ChEMBL_ID":"CHEMBL2106548","KEGG_DRUG":"D07236","DRUGBANK_ID":"DB13686","PUBCHEM_CID":"71807","SNOMEDCT_US":"713466003","IUPHAR_LIGAND_ID":"12294","MESH_SUPPLEMENTAL_RECORD_UI":"C010434"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":2,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"J01CE07","allCodes":["J01CE07"]},"biosimilarFilings":[],"recentPublications":[{"date":"1998 Mar","pmid":"9578165","title":"In-vitro activity of 21 beta-lactam antibiotics against penicillin-susceptible and penicillin-resistant Streptococcus pneumoniae.","journal":"The Journal of antimicrobial chemotherapy"},{"date":"1964 Apr 25","pmid":"14145726","title":"[USE IN CHILDREN OF A NEW ORAL PENICILLIN: CLOMETOCILLIN].","journal":"Gazette medicale de France"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Clometacillin is a small molecule antibiotic. It is also known by synonyms such as CLOMETOCILINA, CLOMETOCILLIN, and CLOMETOCILLINE.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}