{"id":"clofedanol","rwe":[{"pmid":"9548292","year":"1998","title":"Stereoselective interaction of drug enantiomers with human serum transferrin in capillary zone electrophoresis (II).","finding":"","journal":"Electrophoresis","studyType":"Clinical Study"},{"pmid":"2905706","year":"1988","title":"Identification and differentiation of alkylamine antihistamines and their metabolites in urine by computerized gas chromatography-mass spectrometry.","finding":"","journal":"Journal of chromatography","studyType":"Clinical Study"},{"pmid":"6398399","year":"1984","title":"[Controlled double-blind study on the efficacy of clofedanol-sobrerol in the treatment of pediatric pertussis].","finding":"","journal":"Minerva pediatrica","studyType":"Clinical Study"},{"pmid":"604421","year":"1977","title":"[Isolation and identification of some metabolites of clofedanol from human urine (author's transl].","finding":"","journal":"Journal of clinical chemistry and clinical biochemistry. 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chlophedianol (BAN), sold under the brand name Ninjacof among others, is a centrally acting cough suppressant used in the treatment of dry cough. Clofedanol has local anesthetic, antispasmodic, and antihistamine properties, and may have anticholinergic effects at high doses.","wiki_society_and_culture":"==Society and culture==\nChlophedianol was approved for OTC status in 1987 by the FDA OTC monograph process and its safety and efficacy data are limited. It was formerly sold over-the-counter in the United States under the trade name Ulo, as a syrup with a dosage of 25 mg/5 mL. It is now marketed under the brand name of Ninjacof and others in the U.S.\n\nIt is marketed in Canada under the trade name Ulone. GM Pharmaceuticals owns the patents to 113 combinations with Chlophedianol and was the first company to launch the cough suppressant in the United States. \n\nIt is sold in Japan as an over-the-counter drug under the name Coldrin. It has been marketed in Germany as Pectolitan and in Spain as Gentos."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/585","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=clofedanol","fields":["publications"],"source":"PubMed/NCBI"},{"id":3,"url":"https://en.wikipedia.org/wiki/Clofedanol","fields":["history","overview"],"source":"Wikipedia"}],"_enrichedAt":"2026-03-30T10:11:39.919039","_validation":{"fieldsValidated":0,"lastValidatedAt":"2026-04-20T00:02:25.085596+00:00","fieldsConflicting":1,"overallConfidence":0.8},"biosimilars":[],"competitors":[{"drugName":"benzonatate","drugSlug":"benzonatate","fdaApproval":"1958-02-10","genericCount":13,"patentStatus":"Off-patent — generic 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