{"id":"clobenztropine","rwe":[],"tags":[{"label":"clobenztropine","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"teprin","offLabel":[],"synonyms":["clobenztropine","teprin"],"timeline":[],"approvals":[],"brandName":"Teprin","ecosystem":[],"mechanism":{"target":"Sodium-dependent dopamine transporter","modality":"Small Molecule","drugClass":"clobenztropine","explanation":"Think of neurotransmitters like messengers that help different parts of the brain talk to each other. Teprin is thought to help regulate the activity of these messengers, which can help to balance brain chemistry and alleviate symptoms of certain conditions. By doing so, Teprin may help to improve mood, reduce anxiety, or enhance cognitive function.","oneSentence":"Teprin is believed to work by modulating certain neurotransmitter systems in the brain.","technicalDetail":"Clobenztropine is a muscarinic antagonist with potential activity at other neurotransmitter receptors, including dopamine and serotonin receptors. Its exact mechanism of action is unclear, but it may involve modulation of the cholinergic system and other neurotransmitter pathways."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3715","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=CLOBENZTROPINE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T10:10:36.055478","biosimilars":[],"competitors":[{"drugName":"amfetamine","drugSlug":"amfetamine","fdaApproval":"1955-09-09","relationship":"same-target"},{"drugName":"armodafinil","drugSlug":"armodafinil","fdaApproval":"2007-06-05","genericCount":6,"patentStatus":"Off-patent — generic available","relationship":"same-target"},{"drugName":"atomoxetine","drugSlug":"atomoxetine","fdaApproval":"2002-11-26","genericCount":8,"patentStatus":"Off-patent — generic available","relationship":"same-target"},{"drugName":"benzatropine","drugSlug":"benzatropine","fdaApproval":"1954-03-05","relationship":"same-target"},{"drugName":"bupropion","drugSlug":"bupropion","fdaApproval":"1985-12-30","patentExpiry":"Jun 27, 2026","patentStatus":"Patent protected","relationship":"same-target"},{"drugName":"caramiphen","drugSlug":"caramiphen","fdaApproval":"","relationship":"same-target"},{"drugName":"citalopram","drugSlug":"citalopram","fdaApproval":"1998-07-17","genericCount":26,"patentStatus":"Off-patent — generic available","relationship":"same-target"},{"drugName":"desipramine","drugSlug":"desipramine","fdaApproval":"1964-11-20","genericCount":8,"patentStatus":"Off-patent — generic available","relationship":"same-target"},{"drugName":"dexamfetamine","drugSlug":"dexamfetamine","fdaApproval":"1955-09-09","relationship":"same-target"},{"drugName":"dexmethylphenidate","drugSlug":"dexmethylphenidate","fdaApproval":"2001-11-13","genericCount":19,"patentStatus":"Off-patent — generic available","relationship":"same-target"}],"dataSources":[{"url":"https://drugcentral.org","name":"DrugCentral","fields":["indications","contraindications","safety","target","drugInteractions"],"retrievedDate":"2026-04-07"}],"genericName":"clobenztropine","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"amfetamine","brandName":"amfetamine","genericName":"amfetamine","approvalYear":"1955","relationship":"same-target"},{"drugId":"armodafinil","brandName":"armodafinil","genericName":"armodafinil","approvalYear":"2007","relationship":"same-target"},{"drugId":"atomoxetine","brandName":"atomoxetine","genericName":"atomoxetine","approvalYear":"2002","relationship":"same-target"},{"drugId":"benzatropine","brandName":"benzatropine","genericName":"benzatropine","approvalYear":"1954","relationship":"same-target"},{"drugId":"bupropion","brandName":"bupropion","genericName":"bupropion","approvalYear":"1985","relationship":"same-target"},{"drugId":"caramiphen","brandName":"caramiphen","genericName":"caramiphen","approvalYear":"","relationship":"same-target"},{"drugId":"citalopram","brandName":"citalopram","genericName":"citalopram","approvalYear":"1998","relationship":"same-target"},{"drugId":"desipramine","brandName":"desipramine","genericName":"desipramine","approvalYear":"1964","relationship":"same-target"},{"drugId":"dexamfetamine","brandName":"dexamfetamine","genericName":"dexamfetamine","approvalYear":"1955","relationship":"same-target"},{"drugId":"dexmethylphenidate","brandName":"dexmethylphenidate","genericName":"dexmethylphenidate","approvalYear":"2001","relationship":"same-target"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"administration":{},"crossReferences":{"UNII":"M8CDT278F8","CHEBI":"CHEBI:135452","INN_ID":"1388","UMLSCUI":"C5420916","ChEMBL_ID":"CHEMBL2146132","PUBCHEM_CID":"1687"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":0,"therapeuticAreas":["Neuroscience"],"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Teprin, also known as clobenztropine, is a small molecule drug of the clobenztropine class. Its exact target and mechanism of action are unknown, but it is believed to work by modulating certain neurotransmitter systems in the brain. Teprin is not FDA-approved for any indications, and its commercial status, including patent status and generic availability, is also unknown. As a result, there is limited information available on its safety profile, pharmacokinetics, and clinical use. Further research is needed to fully understand the properties and potential applications of Teprin.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}