{"id":"clefamide","rwe":[{"pmid":"5305335","year":"1968","title":"[Comparative study on 3 amebicides: teclozine, clefamide and a combination of clefamide and iodo-chloro-oxyquinolines and streptomycin].","finding":"","journal":"Hospital (Rio de Janeiro, Brazil)","studyType":"Clinical Study"},{"pmid":"5304650","year":"1967","title":"[Side effects of Clefamide].","finding":"","journal":"Hospital (Rio de Janeiro, Brazil)","studyType":"Clinical Study"},{"pmid":"5633827","year":"1967","title":"[Treatment of acute ulcerous intestinal amebiasis with clefamide].","finding":"","journal":"La Prensa medica mexicana","studyType":"Clinical Study"},{"pmid":"5994555","year":"1966","title":"[Chemoprophylaxis of amebiasis with Clefamide in an open community].","finding":"","journal":"Revista do Instituto de Medicina Tropical de Sao Paulo","studyType":"Clinical Study"},{"pmid":"6015291","year":"1966","title":"[Chemioprophylaxis of amebiasis using clefamide in an open community].","finding":"","journal":"Gaceta medica de Mexico","studyType":"Clinical Study"}],"tags":[{"label":"clefamide","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"P01AC02","category":"atc"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"chlorphenoxamide","offLabel":[],"synonyms":["clefamide","chlorophenoxamide","chlorphenoxamide"],"timeline":[],"approvals":[],"brandName":"Chlorphenoxamide","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"clefamide","explanation":"Think of it like a key that unlocks a specific door in a cell. When this door is unlocked, it allows the cell to function differently, which can help treat certain conditions. However, the exact details of how this works are still unknown.","oneSentence":"Clefamide is believed to work by modulating certain cellular processes.","technicalDetail":"The technical details of clefamide's mechanism of action are unclear, but it is thought to involve the modulation of cellular processes through interaction with specific molecular targets."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/4393","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=CLEFAMIDE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T10:09:32.043360","biosimilars":[],"competitors":[],"genericName":"clefamide","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"4AZ2V8K4EK","CHEBI":"CHEBI:135963","INN_ID":"1522","UMLSCUI":"C0610174","ChEMBL_ID":"CHEMBL1788400","KEGG_DRUG":"D07354","DRUGBANK_ID":"DB13512","PUBCHEM_CID":"71819","MESH_SUPPLEMENTAL_RECORD_UI":"C024701"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":5,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"P01AC02","allCodes":["P01AC02"]},"biosimilarFilings":[],"recentPublications":[{"date":"1968 Nov","pmid":"5305335","title":"[Comparative study on 3 amebicides: teclozine, clefamide and a combination of clefamide and iodo-chloro-oxyquinolines and streptomycin].","journal":"Hospital (Rio de Janeiro, Brazil)"},{"date":"1967 Sep","pmid":"5304650","title":"[Side effects of Clefamide].","journal":"Hospital (Rio de Janeiro, Brazil)"},{"date":"1967 Jan-Feb","pmid":"5633827","title":"[Treatment of acute ulcerous intestinal amebiasis with clefamide].","journal":"La Prensa medica mexicana"},{"date":"1966 Sep-Oct","pmid":"5994555","title":"[Chemoprophylaxis of amebiasis with Clefamide in an open community].","journal":"Revista do Instituto de Medicina Tropical de Sao Paulo"},{"date":"1966 Feb","pmid":"6015291","title":"[Chemioprophylaxis of amebiasis using clefamide in an open community].","journal":"Gaceta medica de Mexico"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Chlorphenoxamide is a small molecule with synonyms including Clefamida, Clefamide, and Clefamide.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}