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Keep out of reach of children. In case of overdose, contact a physician or Poison Control Center right away. Tamper Evident: Sealed for your protection. Do not use if seal is broken or missing."],"questions":["QUESTIONS: Dist. By: Deseret Biologicals, Inc. 469 W. 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They have not been reviewed by the Food and Drug Administration."],"dosage_and_administration":["DIRECTIONS: 1-10 drops under the tongue, 3 times a day or as directed by a health professional. Consult a physician for use in children under 12 years of age."],"spl_product_data_elements":["Vascuflow Melatonin, L-Arginine, L-Citrulline, Ubidecarenonum, Squalene, Calcarea Carbonica, Cholesterinum, Coumarinum, Formalinum, Gelsemium Sempervirens, Alpha-Lipoicum Acidum, Mercurius Corrosivus, Plumbum Metallicum, Pantothenic Acid, Glonoinum, Lycopodium Clavatum, Phosphorus, Berberis Vulgaris, Red Yeast Rice, Nitric Oxide, Proteus (Morgani), Rhus Tox MELATONIN MELATONIN ARGININE ARGININE CITRULLINE CITRULLINE UBIDECARENONE UBIDECARENONE SQUALENE SQUALENE OYSTER SHELL CALCIUM CARBONATE, CRUDE OYSTER SHELL CALCIUM CARBONATE, CRUDE CHOLESTEROL CHOLESTEROL COUMARIN COUMARIN FORMALDEHYDE FORMALDEHYDE GELSEMIUM SEMPERVIRENS ROOT GELSEMIUM SEMPERVIRENS ROOT THIOCTIC ACID .ALPHA.-LIPOIC ACID MERCURIC CHLORIDE MERCURIC CATION LEAD LEAD PANTOTHENIC ACID PANTOTHENIC ACID NITROGLYCERIN NITROGLYCERIN LYCOPODIUM CLAVATUM SPORE LYCOPODIUM CLAVATUM SPORE PHOSPHORUS PHOSPHORUS BERBERIS VULGARIS ROOT BARK BERBERIS VULGARIS ROOT BARK MONASCUS PURPUREUS MONASCUS PURPUREUS NITRIC OXIDE NITRIC OXIDE PROTEUS MORGANII PROTEUS MORGANII TOXICODENDRON PUBESCENS LEAF TOXICODENDRON PUBESCENS LEAF WATER ALCOHOL"],"keep_out_of_reach_of_children":["KEEP OUT OF REACH OF CHILDREN: In case of overdose, contact a physician or Poison Control Center right away."],"package_label_principal_display_panel":["PACKAGE LABEL DISPLAY: Des Bio Vascuflow Homeopathic NDC 43742-1554-1 1 FL OZ (30 ml) Vascuflow"]},"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Intramuscular","category":"route"},{"label":"Injection","category":"form"},{"label":"Active","category":"status"},{"label":"Nantes University Hospital","category":"company"}],"phase":"marketed","safety":{"boxedWarnings":[],"safetySignals":[{"date":"","signal":"BODY TEMPERATURE INCREASED","source":"FDA FAERS","actionTaken":"1 reports"},{"date":"","signal":"INFLAMMATION","source":"FDA FAERS","actionTaken":"1 reports"},{"date":"","signal":"OEDEMA","source":"FDA FAERS","actionTaken":"1 reports"},{"date":"","signal":"STAPHYLOCOCCAL INFECTION","source":"FDA FAERS","actionTaken":"1 reports"}],"commonSideEffects":[]},"trials":[],"aliases":[],"company":"Nantes University Hospital","patents":[],"pricing":[],"_sources":{"trials":{"url":"https://clinicaltrials.gov/search?intr=Citrulline","method":"api_direct","source":"ClinicalTrials.gov","rawText":"","confidence":1,"sourceType":"ctgov","retrievedAt":"2026-04-20T01:08:21.444809+00:00"},"timeline":{"url":"https://en.wikipedia.org/wiki/Citrulline","method":"deterministic","source":"Wikipedia","rawText":"","confidence":0.8,"sourceType":"wikipedia","retrievedAt":"2026-04-20T01:08:30.021808+00:00"},"regulatory.ca":{"url":"","method":"api_direct","source":"Health Canada DPD","rawText":"","confidence":1,"sourceType":"health_canada_dpd","retrievedAt":"2026-04-20T01:08:28.321838+00:00"},"publicationCount":{"url":"https://pubmed.ncbi.nlm.nih.gov/?term=Citrulline","method":"api_direct","source":"PubMed/NCBI","rawText":"","confidence":1,"sourceType":"pubmed","retrievedAt":"2026-04-20T01:08:29.411868+00:00"},"mechanism.drugClass":{"url":"https://api.fda.gov/drug/label.json","method":"deterministic","source":"FDA Label (EPC)","rawText":"","confidence":1,"sourceType":"fda_label","retrievedAt":"2026-04-20T01:08:19.198970+00:00"},"administration.route":{"url":"","method":"deterministic","source":"FDA Label","rawText":"","confidence":1,"sourceType":"fda_label","retrievedAt":"2026-04-20T01:08:19.199023+00:00"},"indications.approved":{"url":"","method":"ai_extraction","source":"FDA Label + AI","aiModel":"featherless","rawText":"","confidence":0.9,"sourceType":"fda_label","retrievedAt":"2026-04-20T01:08:38.450578+00:00"},"safety.boxedWarnings":{"url":"","method":"deterministic","source":"FDA Label (no boxed warning)","rawText":"","confidence":1,"sourceType":"fda_label","retrievedAt":"2026-04-20T01:08:19.199033+00:00"},"safety.safetySignals":{"url":"https://api.fda.gov/drug/event.json","method":"api_direct","source":"FDA FAERS","rawText":"","confidence":1,"sourceType":"fda_faers","retrievedAt":"2026-04-20T01:08:30.908878+00:00"},"crossReferences.chemblId":{"url":"https://www.ebi.ac.uk/chembl/compound_report_card/CHEMBL444814/","method":"api_direct","source":"ChEMBL (EMBL-EBI)","rawText":"","confidence":1,"sourceType":"chembl","retrievedAt":"2026-04-20T01:08:29.887064+00:00"}},"allNames":"l-citrulline","offLabel":[],"synonyms":["citrulline","L-Citrulline","sigma-Ureidonorvaline"],"timeline":[],"approvals":[{"date":"","orphan":false,"company":"","regulator":"FDA"}],"brandName":"L-Citrulline","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"Standardized Chemical Allergen [EPC]","explanation":"","oneSentence":"","technicalDetail":"L-Citrulline is a precursor to L-arginine, which is then converted into citrulline and nitric oxide through the action of the enzyme nitric oxide synthase (NOS). 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