{"id":"ciprofloxacin-in-dextrose-5-in-plastic-container","rwe":[{"pmid":"41902618","year":"2026","title":"Detection of Listeria monocytogenes from Raw Milk (Nono) in Cows Using Polymerase Chain Reaction.","finding":"","journal":"Foodborne pathogens and disease","studyType":"Clinical Study"},{"pmid":"41901706","year":"2026","title":"Fluoroquinolone-Resistant Avian Pathogenic Escherichia coli Isolated from Asymptomatic Broiler Chickens in a Slaughterhouse in Northern Thailand.","finding":"","journal":"Pathogens (Basel, Switzerland)","studyType":"Clinical Study"},{"pmid":"41901704","year":"2026","title":"Antibiotic Outcomes of Enterococcal Urinary Tract Infections: A Retrospective Analysis from Saudi Arabia and Oman.","finding":"","journal":"Pathogens (Basel, Switzerland)","studyType":"Clinical Study"},{"pmid":"41901350","year":"2026","title":"Employment of a Resazurin Viability-Based Assay for Minimum Inhibitory and Bactericidal Concentration Determination.","finding":"","journal":"Pharmaceuticals (Basel, Switzerland)","studyType":"Clinical Study"},{"pmid":"41900143","year":"2026","title":"The Difluoroboranyl-Fluoroquinolone Derivative \"7a\" Inhibits Bacterial DNA Gyrase and Exhibits Potent Activity Against Ciprofloxacin-Resistant S. aureus In Vitro and In Vivo Using an Acute Pneumonia Model.","finding":"","journal":"Molecules (Basel, Switzerland)","studyType":"Clinical Study"}],"_fda":{"id":"a797de06-c8be-4417-9bac-137dc4931c8b","set_id":"05b2836d-cd3d-4d7f-970c-66ec2d788667","openfda":{"upc":["0371205300050"],"unii":["4BA73M5E37"],"route":["OPHTHALMIC"],"rxcui":["309307"],"spl_id":["a797de06-c8be-4417-9bac-137dc4931c8b"],"brand_name":["ciprofloxacin"],"spl_set_id":["05b2836d-cd3d-4d7f-970c-66ec2d788667"],"package_ndc":["71205-300-05"],"product_ndc":["71205-300"],"generic_name":["CIPROFLOXACIN"],"product_type":["HUMAN PRESCRIPTION DRUG"],"substance_name":["CIPROFLOXACIN HYDROCHLORIDE"],"manufacturer_name":["Proficient Rx LP"],"application_number":["ANDA077568"],"original_packager_product_ndc":["69315-308"]},"version":"3","overdosage":["OVERDOSAGE A topical overdose of ciprofloxacin Ophthalmic Solution may be flushed from the eye(s) with warm tap water."],"description":["DESCRIPTION Ciprofloxacin Ophthalmic Solution is a synthetic, sterile, multiple dose, antimicrobial for topical ophthalmic use. Ciprofloxacin is a fluoroquinolone antibacterial active against a broad spectrum of gram-positive and gram-negative ocular pathogens. It is available as the monohydrochloride monohydrate salt of 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinoline-carboxylic acid. It is a faint to light yellow crystalline powder with a molecular weight of 385.8. Its empirical formula is C 17 H 18 FN 3 O 3 •HCl•H 2 O and its chemical structure is as follows: Ciprofloxacin hydrochloride Ciprofloxacin differs from other quinolones in that it has a fluorine atom at the 6-position, a piperazine moiety at the 7-position, and a cyclopropyl ring at the 1-position. Each mL of Ciprofloxacin Ophthalmic Solution contains: Active: ciprofloxacin HCl 3.5 mg equivalent to 3 mg base. Preservative: benzalkonium chloride 0.006%. Inactives: sodium acetate, acetic acid, mannitol 4.6%, edetate disodium 0.05%, hydrochloric acid and/or sodium hydroxide (to adjust pH) and water for injection. The pH is approximately 4.5 and the osmolality is approximately 300 mOsm. Ciprofloxacin hydrochloride"],"precautions":["PRECAUTIONS General: As with other antibacterial preparations, prolonged use of ciprofloxacin may result in overgrowth of nonsusceptible organisms, including fungi. If superinfection occurs, appropriate therapy should be initiated. Whenever clinical judgment dictates, the patient should be examined with the aid of magnification, such as slit lamp biomicroscopy and, where appropriate, fluorescein staining. Ciprofloxacin should be discontinued at the first appearance of a skin rash or any other sign of hypersensitivity reaction. In clinical studies of patients with bacterial corneal ulcer, a white crystalline precipitate located in the superficial portion of the corneal defect was observed in 35 (16.6%) of 210 patients. The onset of the precipitate was within 24 hours to 7 days after starting therapy. In one patient, the precipitate was immediately irrigated out upon its appearance. In 17 patients, resolution of the precipitate was seen in 1 to 8 days (seven within the first 24 to 72 hours), in five patients, resolution was noted in 10 to 13 days. In nine patients, exact resolution days were unavailable; however, at follow-up examinations, 18 to 44 days after onset of the event, complete resolution of the precipitate was noted. In three patients, outcome information was unavailable. The precipitate did not preclude continued use of ciprofloxacin, nor did it adversely affect the clinical course of the ulcer or visual outcome. ( see Adverse Reactions ). Information for patients: Do not touch dropper tip to any surface, as this may contaminate the solution. Drug Interactions: Specific drug interaction studies have not been conducted with ophthalmic ciprofloxacin. However, the systemic administration of some quinolones has been shown to elevate plasma concentrations of theophylline, interfere with the metabolism of caffeine, enhance the effects of the oral anticoagulant, warfarin, and its derivatives, and has been associated with transient elevations in serum creatinine in patients receiving cyclosporine concomitantly. Carcinogenesis, Mutagenesis, Impairment of Fertility: Eight in vitro mutagenicity tests have been conducted with ciprofloxacin and the test results are listed below: Salmonella /Microsome Test (Negative) E. coli DNA Repair Assay (Negative) Mouse Lymphoma Cell Forward Mutation Assay (Positive) Chinese Hamster V 79 Cell HGPRT Test (Negative) Syrian Hamster Embryo Cell Transformation Assay (Negative) Saccharomyces cerevisiae Point Mutation Assay (Negative) Saccharomyces cerevisiae Mitotic Crossover and Gene Conversion Assay (Negative) Rat Hepatocyte DNA Repair Assay (Positive) Thus, two of the eight tests were positive, but the results of the following three in vivo test systems gave negative results: Rat Hepatocyte DNA Repair Assay Micronucleus Test (Mice) Dominant Lethal Test (Mice). Long term carcinogenicity studies in mice and rats have been completed. After daily oral dosing for up to two years, there is no evidence that ciprofloxacin had any carcinogenic or tumorigenic effects in these species. Pregnancy: Pregnancy Category C: Reproduction studies have been performed in rats and mice at doses up to six times the usual daily human oral dose and have revealed no evidence of impaired fertility or harm to the fetus due to ciprofloxacin. In rabbits, as with most antimicrobial agents, ciprofloxacin (30 and 100 mg/kg orally) produced gastrointestinal disturbances resulting in maternal weight loss and an increased incidence of abortion. No teratogenicity was observed at either dose. After intravenous administration, at doses up to 20 mg/kg, no maternal toxicity was produced and no embryotoxicity or teratogenicity was observed. There are no adequate and well controlled studies in pregnant women. Ciprofloxacin Ophthalmic Solution should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Nursing Mothers: It is not known whether topically applied ciprofloxacin is excreted in human milk. However, it is known that orally administered ciprofloxacin is excreted in the milk of lactating rats and oral ciprofloxacin has been reported in human breast milk after a single 500 mg dose. Caution should be exercised when Ciprofloxacin Ophthalmic Solution is administered to a nursing mother. Pediatric Use: The safety and effectiveness of Ciprofloxacin ophthalmic solution 0.3% have been established in all ages. Use of Ciprofloxacin ophthalmic solution is supported by evidence from adequate and well controlled studies of Ciprofloxacin ophthalmic solution in adults, children and neonates [ see Clinical Studies ]. Although ciprofloxacin and other quinolones cause arthropathy in immature animals after oral administration, topical ocular administration of ciprofloxacin to immature animals did not cause any arthropathy and there is no evidence that the ophthalmic dosage form has any effect on the weight bearing joints. Geriatric Use: No overall differences in safety or effectiveness have been observed between elderly and younger patients."],"how_supplied":["HOW SUPPLIED As a sterile ophthalmic solution: 5 mL in translucent LDPE bottle with insert cap assembly comprising of a tan colored HDPE screw cap over a LDPE nozzle with tamper evident LDPE dust cover sealing the bottle cap. 5 mL – NDC 71205-300-05 STORAGE CONDITIONS Store at 25°C (77°F); excursions permitted 15°C to 30°C (59°F to 86°F) [See USP controlled room temperature]. Retain in carton until contents are used and protect from light. ANIMAL PHARMACOLOGY Ciprofloxacin and related drugs have been shown to cause arthropathy in immature animals of most species tested following oral administration. However, a one month topical ocular study using immature Beagle dogs did not demonstrate any articular lesions. CLINICAL STUDIES Following therapy with Ciprofloxacin ophthalmic solution, 76% of the patients with corneal ulcers and positive bacterial cultures were clinically cured and complete re-epithelialisation occurred in about 92% of the ulcers. In 3 and 7 day multicenter clinical trials, 52% of the patients with conjunctivitis and positive conjunctival cultures were clinically cured and 70-80% had all causative pathogens eradicated by the end of treatment. In a randomized, double-masked, multicenter, parallel-group clinical trial of pediatric patients with bacterial conjunctivitis, between birth and 31 days of age, patients were dosed with Ciprofloxacin ophthalmic solution or another anti-infective agent. Clinical outcomes for the trial demonstrated a clinical cure rate of 80% at Day 9 and a microbiological eradication success rate of 85% at Day 9. Please note that microbiologic eradication does not always correlate with clinical outcome in anti-infective trials. Rx Only Distributed by: Leading Pharma, LLC. Fairfield, NJ07004 Manufactured By: FDC Limited, B-8, MIDC Industrial Area, Waluj, Aurangabad - 431 136, Maharashtra, India Revision: 12/2017 STERILE OPHTHALMIC SOLUTION CIPROFLOXACIN OPHTHALMIC SOLUTION USP 0.3% as base INSTRUCTIONS FOR USE Read this Instruction for Use before you start using Ciprofloxacin ophthalmic solution and each time you get a refill. There may be new information. This information does not take the place of talking to your doctor about your medical condition or your treatment. Use Ciprofloxacin ophthalmic solution as prescribed by your doctor. Ask your doctor if you have questions about how to use Ciprofloxacin ophthalmic solution. Important information: • Ciprofloxacin ophthalmic solution is for use in the eye only. Ciprofloxacin ophthalmic solution should not be injected into the eye. • If you use other medicines in your eye, wait at least 10 minutes between using Ciprofloxacin ophthalmic solution and your other eye medicines. • If you wear contact lenses, remove them before using Ciprofloxacin ophthalmic solution. Wait at least 15 minutes after using Ciprofloxacin ophthalmic solution before placing your contact lenses back in your eyes. • Do not touch your eye, fingers, or other surfaces with the tip of the Ciprofloxacin ophthalmic solution bottle. You may get bacteria on the tip of the bottle that can cause you to get an eye infection. This eye infection can lead to serious eye damage or vision loss. If you think you have gotten bacteria on the tip of the bottle or you have an eye infection, call your doctor right away. • Wash your hands before each use. Before you use a bottle of Ciprofloxacin ophthalmic solution for the first time: • Check the expiration date on the bottle before use. Do not use Ciprofloxacin ophthalmic solution if the expiration date has passed. • Check that the seal on the dust cover is not broken or missing. Do not use the medicine if the seal is broken or missing. Call your doctor or pharmacist. Each time you use Ciprofloxacin ophthalmic solution: Step 1: Turn the dust cover clockwise to break the seal. Step 2: Remove the dust cover and throw it away. Step 3: Turn the tan coloured cap anti-clockwise and remove. Place the cap on a clean flat surface. Step 4: Tilt your head backwards. Step 5: Turn the bottle upside down and place the tip of the bottle close to your eye. Do not touch your eye with the tip. Pull your lower eyelid downward and look up. Gently squeeze the bottle and let 1 drop fall into the space between your lower eyelid and your eye. If a drop misses your eye, repeat Step 5. Step 6: Replace the tan coloured cap back on the bottle and turn it clockwise to close. Step 7: Remove any extra solution from skin around the eyes with a tissue. • If your doctor has told you to use drops in both eyes, repeat Step 5 for your other eye. • The Ciprofloxacin ophthalmic solution bottle tip is made to give a certain amount of medicine in 1 drop. Do not make the opening of the bottle tip bigger or you may get too much Ciprofloxacin ophthalmic solution. • After you use all of the doses of Ciprofloxacin ophthalmic solution that your doctor has prescribed, there will be some medicine left in the bottle. Do not use the extra medicine in the bottle. Throw the bottle away. How should I store Ciprofloxacin ophthalmic solution? • Store at 25°C (77°F); excursions permitted 15°C to 30°C (59°F to 86°F) [See USP controlled room temperature]. • Retain in carton until contents are used and protect from light Keep Ciprofloxacin ophthalmic solution and all medicines out of the reach of children. This Instruction for Use has been approved by the U.S. Food and Drug Administration. Distributed by: Leading Pharma, LLC. Fairfield, NJ07004 Manufactured By: FDC Limited, B-8, MIDC Industrial Area, Waluj, Aurangabad - 431 136, Maharashtra, India Relabeled By: Proficient Rx LP Thousand Oaks, CA 91320 Revision: 12/2017 Fig 1 fig 2 fig 2 fig 4 fig 5 fig 6 fig 7 fig 8"],"geriatric_use":["Geriatric Use: No overall differences in safety or effectiveness have been observed between elderly and younger patients."],"pediatric_use":["Pediatric Use: The safety and effectiveness of Ciprofloxacin ophthalmic solution 0.3% have been established in all ages. Use of Ciprofloxacin ophthalmic solution is supported by evidence from adequate and well controlled studies of Ciprofloxacin ophthalmic solution in adults, children and neonates [ see Clinical Studies ]. Although ciprofloxacin and other quinolones cause arthropathy in immature animals after oral administration, topical ocular administration of ciprofloxacin to immature animals did not cause any arthropathy and there is no evidence that the ophthalmic dosage form has any effect on the weight bearing joints."],"effective_time":"20220502","nursing_mothers":["Nursing Mothers: It is not known whether topically applied ciprofloxacin is excreted in human milk. However, it is known that orally administered ciprofloxacin is excreted in the milk of lactating rats and oral ciprofloxacin has been reported in human breast milk after a single 500 mg dose. Caution should be exercised when Ciprofloxacin Ophthalmic Solution is administered to a nursing mother."],"adverse_reactions":["ADVERSE REACTIONS The most frequently reported drug related adverse reaction was local burning or discomfort. In corneal ulcer studies with frequent administration of the drug, white crystalline precipitates were seen in approximately 17% of patients ( see Precautions ). Other reactions occurring in less than 10% of patients included lid margin crusting, crystals/scales, foreign body sensation, itching, conjunctival hyperemia and a bad taste following instillation. Additional events occurring in less than 1% of patients included corneal staining, keratopathy/keratitis, allergic reactions, lid edema, tearing, photophobia, corneal infiltrates, nausea and decreased vision. To report SUSPECTED ADVERSE REACTIONS, contact LEADING PHARMA AT 1-844-740-7500 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch"],"contraindications":["CONTRAINDICATIONS A history of hypersensitivity to ciprofloxacin or any other component of the medication is a contraindication to its use. A history of hypersensitivity to other quinolones may also contraindicate the use of ciprofloxacin."],"drug_interactions":["Drug Interactions: Specific drug interaction studies have not been conducted with ophthalmic ciprofloxacin. However, the systemic administration of some quinolones has been shown to elevate plasma concentrations of theophylline, interfere with the metabolism of caffeine, enhance the effects of the oral anticoagulant, warfarin, and its derivatives, and has been associated with transient elevations in serum creatinine in patients receiving cyclosporine concomitantly."],"clinical_pharmacology":["CLINICAL PHARMACOLOGY Systemic Absorption: A systemic absorption study was performed in which Ciprofloxacin Ophthalmic Solution was administered in each eye every two hours while awake for two days followed by every four hours while awake for an additional 5 days. The maximum reported plasma concentration of ciprofloxacin was less than 5 ng/mL. The mean concentration was usually less than 2.5 ng/mL. Microbiology : Ciprofloxacin has in vitro activity against a wide range of gram-negative and gram-positive organisms. The bactericidal action of ciprofloxacin results from interference with the enzyme DNA gyrase which is needed for the synthesis of bacterial DNA. Ciprofloxacin has been shown to be active against most strains of the following organisms both in vitro and in clinical infections ( see Indications and Usage ): Gram-Positive: Staphylococcus aureus Staphylococcus epidermidis Streptococcus pneumoniae Streptococcus (Viridans Group) Gram-Negative: Haemophilus influenzae Pseudomonas aeruginosa Serratia marcescens Ciprofloxacin has been shown to be active in vitro against most strains of the following organisms, however, the clinical significance of these data is unknown: Gram-Positive: Enterococcus faecalis (Many strains are only moderately susceptible) Staphylococcus haemolyticus Staphylococcus hominis Staphylococcus saprophyticus Streptococcus pyogenes Gram-Negative Acinetobacter calcoaceticus subsp. anitratus Aeromonas caviae Aeromonas hydrophila Brucella melitensis Campylobacter coli Campylobacter jejuni Citrobacter diversus Citrobacter freundii Edwardsiella tarda Enterobacter aerogenes Enterobacter cloacae Escherichia coli Haemophilus ducreyi Haemophilus parainfluenzae Kiebsiella pneumoniae Klebsiella oxytoca Legionella pneumophila Moraxella (Branhamella) catarrhalis Morganella morganii Neisseria gonorrhoeae Neisseria meningitides Pasteurella multocida Proteus mirabilis Proteus vulgaris Providencia rettgeri Providencia stuartii Salmonella enteritidis Salmonella typhi Shigella sonneii Shigella flexneri Vibrio cholera Vibrio parahaemolyticus Vibrio vulnificus Yersinia enterocolitica Other Organisms: Chlamydia trachomatis (only moderately susceptible) and Mycobacterium tuberculosis (only moderately susceptible). Most strains of Pseudomonas cepacia and some strains of Pseudomonas maltophilia are resistant to ciprofloxacin as are most anaerobic bacteria, including Bacteroides fragilis and Clostridium difficile. The minimal bactericidal concentration (MBC) generally does not exceed the minimal inhibitory concentration (MIC) by more than a factor of 2. Resistance to ciprofloxacin in vitro usually develops slowly (multiple-step mutation). Ciprofloxacin does not cross-react with other antimicrobial agents such as beta-lactams or aminoglycosides; therefore, organisms resistant to these drugs may be susceptible to ciprofloxacin."],"indications_and_usage":["INDICATIONS AND USAGE Ciprofloxacin Ophthalmic Solution is indicated for the treatment of infections caused by susceptible strains of the designated microorganisms in the conditions listed below: Corneal Ulcers: Pseudomonas aeruginosa Serratia marcescens * Staphylococcus aureus Staphylococcus epidermidis Streptococcus pneumoniae Streptococcus (Viridans Group) * Conjunctivitis: Haemophilus influenzae Staphylococcus aureus Staphylococcus epidermidis Streptococcus pneumoniae *Efficacy for this organism was studied in fewer than 10 infections."],"warnings_and_cautions":["WARNINGS NOT FOR INJECTION INTO THE EYE. Serious and occasionally fatal hypersensitivity (anaphylactic) reactions, some following the first dose, have been reported in patients receiving systemic quinolone therapy. Some reactions were accompanied by cardiovascular collapse, loss of consciousness, tingling, pharyngeal or facial edema, dyspnea, urticaria, and itching. Only a few patients had a history of hypersensitivity reactions. Serious anaphylactic reactions require immediate emergency treatment with epinephrine and other resuscitation measures, including oxygen, intravenous fluids, intravenous antihistamines, corticosteroids, pressor amines and airway management, as clinically indicated. Remove contact lenses before using."],"information_for_patients":["Information for patients: Do not touch dropper tip to any surface, as this may contaminate the solution."],"dosage_and_administration":["DOSAGE AND ADMINISTRATION Corneal Ulcers: The recommended dosage regimen for the treatment of corneal ulcers is two drops into the affected eye every 15 minutes for the first six hours and then two drops into the affected eye every 30 minutes for the remainder of the first day. On the second day, instill two drops in the affected eye hourly. On the third through the fourteenth day, place two drops in the affected eye every four hours. Treatment may be continued after 14 days if corneal re-epithelialisation has not occurred. Bacterial Conjunctivitis: The recommended dosage regimen for the treatment of bacterial conjunctivitis is one or two drops instilled into the conjunctival sac(s) every two hours while awake for two days and one or two drops every four hours while awake for the next five days."],"spl_product_data_elements":["ciprofloxacin Ciprofloxacin CIPROFLOXACIN HYDROCHLORIDE CIPROFLOXACIN SODIUM ACETATE ANHYDROUS ACETIC ACID MANNITOL EDETATE DISODIUM BENZALKONIUM CHLORIDE SODIUM HYDROXIDE HYDROCHLORIC ACID"],"package_label_principal_display_panel":["PACKAGE LABEL.PRINCIPAL DISPLAY PANEL 5 ml Carton Label NDC 71205-300-05 Ciprofloxacin Ophthalmic Solution USP 0.3% as base Rx Only 5 mL Sterile PRECAUTION: Do not touch dropper tip to any surface, as this may contaminate the solution. USUAL DOSAGE: Read enclosed insert. FOR TOPICAL OPHTHALMIC USE ONLY. EACH mL CONTAINS: Active: ciprofloxacin HCl 3.5 mg equivalent to 3 mg ciprofloxacin base. Preservative: benzalkonium chloride 0.006%. Inactives: sodium acetate, acetic acid, mannitol, edetate disodium, hydrochloric acid and/or sodium hydroxide (to adjust pH) and water for injection. STORAGE: Store at 25°C (77°F); excursions permitted 15°C to 30°C (59°F to 86°F) [See USP controlled room temperature].Protect from light. 71205-300-05"]},"tags":[{"label":"Fluoroquinolone Antibacterial","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"DNA topoisomerase II","category":"target"},{"label":"TOP2A","category":"gene"},{"label":"TOP2B","category":"gene"},{"label":"J01MA02","category":"atc"},{"label":"Intravenous","category":"route"},{"label":"Ophthalmic","category":"route"},{"label":"Auricular (Otic)","category":"route"},{"label":"Injection","category":"form"},{"label":"Ointment","category":"form"},{"label":"Solution","category":"form"},{"label":"Solution/ Drops","category":"form"},{"label":"Generic Available","category":"availability"},{"label":"Established","category":"status"},{"label":"Abdominal abscess","category":"indication"},{"label":"Acute Moraxella catarrhalis bronchitis","category":"indication"},{"label":"Acute bacterial bronchitis","category":"indication"},{"label":"Acute bacterial peritonitis","category":"indication"},{"label":"Acute bacterial sinusitis","category":"indication"},{"label":"Acute gonococcal cervicitis","category":"indication"},{"label":"Alk Abello","category":"company"},{"label":"Approved 1980s","category":"decade"},{"label":"Anti-Bacterial Agents","category":"pharmacology"},{"label":"Anti-Infective Agents","category":"pharmacology"},{"label":"Antineoplastic Agents","category":"pharmacology"},{"label":"Cytochrome P-450 CYP1A2 Inhibitors","category":"pharmacology"},{"label":"Cytochrome P-450 Enzyme Inhibitors","category":"pharmacology"},{"label":"Enzyme Inhibitors","category":"pharmacology"},{"label":"Metabolic Side Effects of Drugs and Substances","category":"pharmacology"},{"label":"Topoisomerase II Inhibitors","category":"pharmacology"},{"label":"Topoisomerase Inhibitors","category":"pharmacology"}],"phase":"marketed","fdaNDC":[{"route":[],"labeler":"Quimica Sintetica S.A.","brandName":"","packaging":[{"ndc":"53069-0180-5","description":"20 kg in 1 DRUM (53069-0180-5)","marketingStartDate":"21-FEB-96"}],"dosageForm":"POWDER","genericName":"Ciprofloxacin hydrochloride","productType":"BULK INGREDIENT","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"1 kg/kg"}],"marketingCategory":"BULK INGREDIENT"},{"route":[],"labeler":"Bayer AG","brandName":"","packaging":[{"ndc":"12527-0540-1","description":"50 kg in 1 DRUM (12527-0540-1)","marketingStartDate":"01-SEP-16"}],"dosageForm":"POWDER","genericName":"Ciprofloxacin","productType":"BULK INGREDIENT","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"1 kg/kg"}],"marketingCategory":"BULK INGREDIENT"},{"route":["AURICULAR (OTIC)"],"labeler":"Redpharm Drug","brandName":"Ciprofloxacin and dexamethasone","packaging":[{"ndc":"67296-1943-8","description":"1 BOTTLE, DROPPER in 1 CARTON (67296-1943-8)  / 8 mL in 1 BOTTLE, DROPPER","marketingStartDate":"20231101"}],"dosageForm":"SUSPENSION/ DROPS","genericName":"Ciprofloxacin and dexamethasone","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"3 mg/mL"},{"name":"DEXAMETHASONE","strength":"1 mg/mL"}],"marketingCategory":"ANDA"},{"route":["ORAL"],"labeler":"Bryant Ranch Prepack","brandName":"ciprofloxacin","packaging":[{"ndc":"71335-0408-0","description":"7 TABLET in 1 BOTTLE (71335-0408-0)","marketingStartDate":"20220504"},{"ndc":"71335-0408-1","description":"20 TABLET in 1 BOTTLE (71335-0408-1)","marketingStartDate":"20220504"},{"ndc":"71335-0408-2","description":"10 TABLET in 1 BOTTLE (71335-0408-2)","marketingStartDate":"20220504"},{"ndc":"71335-0408-3","description":"14 TABLET in 1 BOTTLE (71335-0408-3)","marketingStartDate":"20220504"},{"ndc":"71335-0408-4","description":"6 TABLET in 1 BOTTLE (71335-0408-4)","marketingStartDate":"20220504"},{"ndc":"71335-0408-5","description":"30 TABLET in 1 BOTTLE (71335-0408-5)","marketingStartDate":"20220504"},{"ndc":"71335-0408-6","description":"60 TABLET in 1 BOTTLE (71335-0408-6)","marketingStartDate":"20220504"},{"ndc":"71335-0408-7","description":"12 TABLET in 1 BOTTLE (71335-0408-7)","marketingStartDate":"20220504"},{"ndc":"71335-0408-8","description":"40 TABLET in 1 BOTTLE (71335-0408-8)","marketingStartDate":"20220504"},{"ndc":"71335-0408-9","description":"90 TABLET in 1 BOTTLE (71335-0408-9)","marketingStartDate":"20220504"}],"dosageForm":"TABLET","genericName":"ciprofloxacin","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"250 mg/1"}],"marketingCategory":"ANDA"},{"route":["ORAL"],"labeler":"PD-Rx Pharmaceuticals, Inc.","brandName":"Ciprofloxacin","packaging":[{"ndc":"43063-923-30","description":"30 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (43063-923-30)","marketingStartDate":"20190510"}],"dosageForm":"TABLET, FILM COATED","genericName":"Ciprofloxacin Hydrochloride","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"500 mg/1"}],"marketingCategory":"ANDA"},{"route":["ORAL"],"labeler":"A-S Medication Solutions","brandName":"Ciprofloxacin","packaging":[{"ndc":"50090-2146-0","description":"6 TABLET, FILM COATED in 1 BOTTLE (50090-2146-0)","marketingStartDate":"20151020"},{"ndc":"50090-2146-1","description":"14 TABLET, FILM COATED in 1 BOTTLE (50090-2146-1)","marketingStartDate":"20151020"},{"ndc":"50090-2146-2","description":"10 TABLET, FILM COATED in 1 BOTTLE (50090-2146-2)","marketingStartDate":"20151020"},{"ndc":"50090-2146-3","description":"3 TABLET, FILM COATED in 1 BOTTLE (50090-2146-3)","marketingStartDate":"20190813"}],"dosageForm":"TABLET, FILM COATED","genericName":"Ciprofloxacin Hydrochloride","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"250 mg/1"}],"marketingCategory":"ANDA"},{"route":[],"labeler":"Fagron Inc","brandName":"","packaging":[{"ndc":"51552-1229-5","description":"100 g in 1 CONTAINER (51552-1229-5)","marketingStartDate":"01-SEP-04"}],"dosageForm":"POWDER","genericName":"Ciprofloxacin HCl","productType":"BULK INGREDIENT","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"1 g/g"}],"marketingCategory":"BULK INGREDIENT FOR HUMAN PRESCRIPTION COMPOUNDING"},{"route":["ORAL"],"labeler":"Proficient Rx LP","brandName":"ciprofloxacin","packaging":[{"ndc":"63187-017-06","description":"6 TABLET in 1 BOTTLE (63187-017-06)","marketingStartDate":"20140801"},{"ndc":"63187-017-10","description":"10 TABLET in 1 BOTTLE (63187-017-10)","marketingStartDate":"20140801"},{"ndc":"63187-017-14","description":"14 TABLET in 1 BOTTLE (63187-017-14)","marketingStartDate":"20140801"},{"ndc":"63187-017-20","description":"20 TABLET in 1 BOTTLE (63187-017-20)","marketingStartDate":"20140801"},{"ndc":"63187-017-28","description":"28 TABLET in 1 BOTTLE (63187-017-28)","marketingStartDate":"20160804"},{"ndc":"63187-017-30","description":"30 TABLET in 1 BOTTLE (63187-017-30)","marketingStartDate":"20140801"},{"ndc":"63187-017-60","description":"60 TABLET in 1 BOTTLE (63187-017-60)","marketingStartDate":"20210723"},{"ndc":"63187-017-90","description":"90 TABLET in 1 BOTTLE (63187-017-90)","marketingStartDate":"20210723"}],"dosageForm":"TABLET","genericName":"ciprofloxacin","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"500 mg/1"}],"marketingCategory":"ANDA"},{"route":["ORAL"],"labeler":"Bryant Ranch Prepack","brandName":"Ciprofloxacin","packaging":[{"ndc":"71335-1024-1","description":"20 TABLET, FILM COATED in 1 BOTTLE (71335-1024-1)","marketingStartDate":"20181228"},{"ndc":"71335-1024-2","description":"28 TABLET, FILM COATED in 1 BOTTLE (71335-1024-2)","marketingStartDate":"20211228"},{"ndc":"71335-1024-3","description":"14 TABLET, FILM COATED in 1 BOTTLE (71335-1024-3)","marketingStartDate":"20181210"},{"ndc":"71335-1024-4","description":"30 TABLET, FILM COATED in 1 BOTTLE (71335-1024-4)","marketingStartDate":"20211228"},{"ndc":"71335-1024-5","description":"60 TABLET, FILM COATED in 1 BOTTLE (71335-1024-5)","marketingStartDate":"20211228"},{"ndc":"71335-1024-6","description":"10 TABLET, FILM COATED in 1 BOTTLE (71335-1024-6)","marketingStartDate":"20181211"},{"ndc":"71335-1024-7","description":"90 TABLET, FILM COATED in 1 BOTTLE (71335-1024-7)","marketingStartDate":"20211228"}],"dosageForm":"TABLET, FILM COATED","genericName":"Ciprofloxacin Hydrochloride","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"750 mg/1"}],"marketingCategory":"ANDA"},{"route":["INTRAVENOUS"],"labeler":"ProPharma Distribution","brandName":"Ciprofloxacin in Dextrose","packaging":[{"ndc":"84549-300-24","description":"200 mL in 1 BAG (84549-300-24)","marketingStartDate":"20251010"}],"dosageForm":"INJECTION, SOLUTION","genericName":"ciprofloxacin","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN","strength":"400 mg/200mL"}],"marketingCategory":"ANDA"},{"route":[],"labeler":"Bayer AG","brandName":"","packaging":[{"ndc":"12527-8513-9","description":"83486 TABLET, FILM COATED in 1 CONTAINER (12527-8513-9)","marketingStartDate":"02-JUL-19"}],"dosageForm":"TABLET, FILM COATED","genericName":"ciprofloxacin hydrochloride","productType":"DRUG FOR FURTHER PROCESSING","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"500 mg/1"}],"marketingCategory":"DRUG FOR FURTHER PROCESSING"},{"route":["ORAL"],"labeler":"Major Pharmaceuticals","brandName":"ciprofloxacin","packaging":[{"ndc":"0904-7243-61","description":"100 BLISTER PACK in 1 CARTON (0904-7243-61)  / 1 TABLET, FILM COATED in 1 BLISTER PACK","marketingStartDate":"20220823"},{"ndc":"0904-7243-95","description":"20 TABLET, FILM COATED in 1 BOTTLE (0904-7243-95)","marketingStartDate":"20220823"}],"dosageForm":"TABLET, FILM COATED","genericName":"ciprofloxacin","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"500 mg/1"}],"marketingCategory":"ANDA"},{"route":[],"labeler":"Bayer AG","brandName":"","packaging":[{"ndc":"12527-8512-9","description":"83486 TABLET, FILM COATED in 1 CONTAINER (12527-8512-9)","marketingStartDate":"02-JUL-19"}],"dosageForm":"TABLET, FILM COATED","genericName":"ciprofloxacin hydrochloride","productType":"DRUG FOR FURTHER PROCESSING","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"250 mg/1"}],"marketingCategory":"DRUG FOR FURTHER PROCESSING"},{"route":["ORAL"],"labeler":"PD-Rx Pharmaceuticals, Inc.","brandName":"Ciprofloxacin","packaging":[{"ndc":"72789-330-06","description":"6 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (72789-330-06)","marketingStartDate":"20230830"},{"ndc":"72789-330-10","description":"10 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (72789-330-10)","marketingStartDate":"20230907"},{"ndc":"72789-330-14","description":"14 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (72789-330-14)","marketingStartDate":"20230814"},{"ndc":"72789-330-20","description":"20 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (72789-330-20)","marketingStartDate":"20230706"},{"ndc":"72789-330-28","description":"28 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (72789-330-28)","marketingStartDate":"20230807"}],"dosageForm":"TABLET, FILM COATED","genericName":"Ciprofloxacin Hydrochloride","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"500 mg/1"}],"marketingCategory":"ANDA"},{"route":["ORAL"],"labeler":"Amneal Pharmaceuticals NY LLC","brandName":"Ciprofloxacin","packaging":[{"ndc":"69238-2434-1","description":"100 TABLET, FILM COATED in 1 BOTTLE (69238-2434-1)","marketingStartDate":"20240229"},{"ndc":"69238-2434-5","description":"50 TABLET, FILM COATED in 1 BOTTLE (69238-2434-5)","marketingStartDate":"20240229"}],"dosageForm":"TABLET, FILM COATED","genericName":"Ciprofloxacin","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"750 mg/1"}],"marketingCategory":"ANDA"},{"route":["ORAL"],"labeler":"Amneal Pharmaceuticals NY LLC","brandName":"Ciprofloxacin","packaging":[{"ndc":"69238-2432-1","description":"100 TABLET, FILM COATED in 1 BOTTLE (69238-2432-1)","marketingStartDate":"20240229"}],"dosageForm":"TABLET, FILM COATED","genericName":"Ciprofloxacin","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"250 mg/1"}],"marketingCategory":"ANDA"},{"route":["ORAL"],"labeler":"Aphena Pharma Solutions - Tennessee, LLC","brandName":"Ciprofloxacin","packaging":[{"ndc":"71610-159-83","description":"3600 TABLET, FILM COATED in 1 BOTTLE (71610-159-83)","marketingStartDate":"20180920"}],"dosageForm":"TABLET, FILM COATED","genericName":"Ciprofloxacin Hydrochloride","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"500 mg/1"}],"marketingCategory":"ANDA"},{"route":["ORAL"],"labeler":"PharmPak, Inc.","brandName":"ciprofloxacin","packaging":[{"ndc":"54348-662-06","description":"1 BOTTLE in 1 BOX (54348-662-06)  / 6 TABLET in 1 BOTTLE","marketingStartDate":"20190710"},{"ndc":"54348-662-14","description":"1 BOTTLE in 1 BOX (54348-662-14)  / 14 TABLET in 1 BOTTLE","marketingStartDate":"20190710"}],"dosageForm":"TABLET","genericName":"CIPROFLOXACIN","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"250 mg/1"}],"marketingCategory":"ANDA"},{"route":["OPHTHALMIC"],"labeler":"Sandoz Inc","brandName":"Ciprofloxacin Hydrochloride","packaging":[{"ndc":"61314-656-05","description":"1 BOTTLE, PLASTIC in 1 CARTON (61314-656-05)  / 5 mL in 1 BOTTLE, PLASTIC","marketingStartDate":"20040507"},{"ndc":"61314-656-10","description":"1 BOTTLE, PLASTIC in 1 CARTON (61314-656-10)  / 10 mL in 1 BOTTLE, PLASTIC","marketingStartDate":"20040507"},{"ndc":"61314-656-25","description":"1 BOTTLE, PLASTIC in 1 CARTON (61314-656-25)  / 2.5 mL in 1 BOTTLE, PLASTIC","marketingStartDate":"20040507"}],"dosageForm":"SOLUTION/ DROPS","genericName":"Ciprofloxacin Hydrochloride","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"3 mg/mL"}],"marketingCategory":"NDA AUTHORIZED GENERIC"},{"route":["ORAL"],"labeler":"PharmPak, Inc.","brandName":"ciprofloxacin","packaging":[{"ndc":"54348-663-01","description":"1 BOTTLE in 1 BOX (54348-663-01)  / 1 TABLET in 1 BOTTLE","marketingStartDate":"20190710"},{"ndc":"54348-663-06","description":"1 BOTTLE in 1 BOX (54348-663-06)  / 6 TABLET in 1 BOTTLE","marketingStartDate":"20190710"},{"ndc":"54348-663-14","description":"1 BOTTLE in 1 BOX (54348-663-14)  / 14 TABLET in 1 BOTTLE","marketingStartDate":"20190710"}],"dosageForm":"TABLET","genericName":"CIPROFLOXACIN","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"500 mg/1"}],"marketingCategory":"ANDA"},{"route":["ORAL"],"labeler":"Amneal Pharmaceuticals NY LLC","brandName":"Ciprofloxacin","packaging":[{"ndc":"69238-2433-1","description":"100 TABLET, FILM COATED in 1 BOTTLE (69238-2433-1)","marketingStartDate":"20240229"}],"dosageForm":"TABLET, FILM COATED","genericName":"Ciprofloxacin","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"500 mg/1"}],"marketingCategory":"ANDA"},{"route":["ORAL"],"labeler":"VERITYRX, LLC","brandName":"Ciprofloxacin Hydrochloride","packaging":[{"ndc":"83939-0002-1","description":"1 TABLET, FILM COATED in 1 POUCH (83939-0002-1)","marketingStartDate":"20251103"},{"ndc":"83939-0002-2","description":"50 POUCH in 1 BOX, UNIT-DOSE (83939-0002-2)  / 1 TABLET, FILM COATED in 1 POUCH","marketingStartDate":"20251103"},{"ndc":"83939-0002-3","description":"100 POUCH in 1 BOX, UNIT-DOSE (83939-0002-3)  / 1 TABLET, FILM COATED in 1 POUCH","marketingStartDate":"20251103"}],"dosageForm":"TABLET, FILM COATED","genericName":"Ciprofloxacin Hydrochloride","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"500 mg/1"}],"marketingCategory":"ANDA"},{"route":["ORAL"],"labeler":"Northwind Health Company, LLC","brandName":"Ciprofloxacin","packaging":[{"ndc":"51655-086-20","description":"20 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (51655-086-20)","marketingStartDate":"20230622"},{"ndc":"51655-086-84","description":"14 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (51655-086-84)","marketingStartDate":"20230301"}],"dosageForm":"TABLET, FILM COATED","genericName":"Ciprofloxacin","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"250 mg/1"}],"marketingCategory":"ANDA"},{"route":["ORAL"],"labeler":"Bryant Ranch Prepack","brandName":"Ciprofloxacin","packaging":[{"ndc":"71335-1867-0","description":"7 TABLET, FILM COATED in 1 BOTTLE (71335-1867-0)","marketingStartDate":"20220214"},{"ndc":"71335-1867-1","description":"20 TABLET, FILM COATED in 1 BOTTLE (71335-1867-1)","marketingStartDate":"20210510"},{"ndc":"71335-1867-2","description":"10 TABLET, FILM COATED in 1 BOTTLE (71335-1867-2)","marketingStartDate":"20210804"},{"ndc":"71335-1867-3","description":"14 TABLET, FILM COATED in 1 BOTTLE (71335-1867-3)","marketingStartDate":"20210712"},{"ndc":"71335-1867-4","description":"6 TABLET, FILM COATED in 1 BOTTLE (71335-1867-4)","marketingStartDate":"20211011"},{"ndc":"71335-1867-5","description":"30 TABLET, FILM COATED in 1 BOTTLE (71335-1867-5)","marketingStartDate":"20220214"},{"ndc":"71335-1867-6","description":"60 TABLET, FILM COATED in 1 BOTTLE (71335-1867-6)","marketingStartDate":"20220214"},{"ndc":"71335-1867-7","description":"12 TABLET, FILM COATED in 1 BOTTLE (71335-1867-7)","marketingStartDate":"20220214"},{"ndc":"71335-1867-8","description":"40 TABLET, FILM COATED in 1 BOTTLE (71335-1867-8)","marketingStartDate":"20220214"},{"ndc":"71335-1867-9","description":"90 TABLET, FILM COATED in 1 BOTTLE (71335-1867-9)","marketingStartDate":"20220214"}],"dosageForm":"TABLET, FILM COATED","genericName":"Ciprofloxacin","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"250 mg/1"}],"marketingCategory":"ANDA"},{"route":["ORAL"],"labeler":"CHARTWELL GOVERNMENTAL & SPECIALTY RX LLC","brandName":"Ciprofloxacin","packaging":[{"ndc":"68999-309-20","description":"20 TABLET, FILM COATED in 1 BOTTLE (68999-309-20)","marketingStartDate":"20200526"},{"ndc":"68999-309-28","description":"28 TABLET, FILM COATED in 1 BOTTLE (68999-309-28)","marketingStartDate":"20200526"}],"dosageForm":"TABLET, FILM COATED","genericName":"Ciprofloxacin hydrochloride","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"500 mg/1"}],"marketingCategory":"ANDA"},{"route":["ORAL"],"labeler":"PD-Rx Pharmaceuticals, Inc.","brandName":"Ciprofloxacin","packaging":[{"ndc":"72789-065-20","description":"20 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (72789-065-20)","marketingStartDate":"20200323"}],"dosageForm":"TABLET, FILM COATED","genericName":"Ciprofloxacin Hydrochloride","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"500 mg/1"}],"marketingCategory":"ANDA"},{"route":["ORAL"],"labeler":"NuCare Pharmaceuticals,Inc.","brandName":"Ciprofloxacin","packaging":[{"ndc":"68071-2384-1","description":"10 TABLET, COATED in 1 BOTTLE (68071-2384-1)","marketingStartDate":"20210409"},{"ndc":"68071-2384-2","description":"20 TABLET, COATED in 1 BOTTLE (68071-2384-2)","marketingStartDate":"20210409"},{"ndc":"68071-2384-3","description":"30 TABLET, COATED in 1 BOTTLE (68071-2384-3)","marketingStartDate":"20210409"},{"ndc":"68071-2384-4","description":"14 TABLET, COATED in 1 BOTTLE (68071-2384-4)","marketingStartDate":"20210409"},{"ndc":"68071-2384-5","description":"15 TABLET, COATED in 1 BOTTLE (68071-2384-5)","marketingStartDate":"20210409"},{"ndc":"68071-2384-6","description":"60 TABLET, COATED in 1 BOTTLE (68071-2384-6)","marketingStartDate":"20210409"},{"ndc":"68071-2384-7","description":"21 TABLET, COATED in 1 BOTTLE (68071-2384-7)","marketingStartDate":"20210409"},{"ndc":"68071-2384-8","description":"28 TABLET, COATED in 1 BOTTLE (68071-2384-8)","marketingStartDate":"20210409"},{"ndc":"68071-2384-9","description":"90 TABLET, COATED in 1 BOTTLE (68071-2384-9)","marketingStartDate":"20210409"}],"dosageForm":"TABLET, COATED","genericName":"Ciprofloxacin","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"500 mg/1"}],"marketingCategory":"ANDA"},{"route":["OPHTHALMIC"],"labeler":"REMEDYREPACK INC.","brandName":"Ciprofloxacin Hydrochloride","packaging":[{"ndc":"70518-1170-0","description":"1 BOTTLE, PLASTIC in 1 CARTON (70518-1170-0)  / 5 mL in 1 BOTTLE, PLASTIC","marketingStartDate":"20180515"}],"dosageForm":"SOLUTION/ DROPS","genericName":"Ciprofloxacin Hydrochloride","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"3 mg/mL"}],"marketingCategory":"NDA AUTHORIZED GENERIC"},{"route":["AURICULAR (OTIC)"],"labeler":"NuCare Pharmaceutical, Inc.","brandName":"Ciprofloxacin and dexamethasone","packaging":[{"ndc":"68071-3977-7","description":"1 BOTTLE, DROPPER in 1 CARTON (68071-3977-7)  / 7.5 mL in 1 BOTTLE, DROPPER","marketingStartDate":"20260319"}],"dosageForm":"SUSPENSION/ DROPS","genericName":"Ciprofloxacin and dexamethasone","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"3 mg/mL"},{"name":"DEXAMETHASONE","strength":"1 mg/mL"}],"marketingCategory":"ANDA"},{"route":["ORAL"],"labeler":"NuCare Pharmaceuticals,Inc.","brandName":"Ciprofloxacin","packaging":[{"ndc":"68071-2383-1","description":"10 TABLET, COATED in 1 BOTTLE (68071-2383-1)","marketingStartDate":"20210406"},{"ndc":"68071-2383-2","description":"20 TABLET, COATED in 1 BOTTLE (68071-2383-2)","marketingStartDate":"20210406"},{"ndc":"68071-2383-3","description":"30 TABLET, COATED in 1 BOTTLE (68071-2383-3)","marketingStartDate":"20210406"},{"ndc":"68071-2383-4","description":"14 TABLET, COATED in 1 BOTTLE (68071-2383-4)","marketingStartDate":"20210406"},{"ndc":"68071-2383-8","description":"28 TABLET, COATED in 1 BOTTLE (68071-2383-8)","marketingStartDate":"20210406"},{"ndc":"68071-2383-9","description":"90 TABLET, COATED in 1 BOTTLE (68071-2383-9)","marketingStartDate":"20210406"}],"dosageForm":"TABLET, COATED","genericName":"Ciprofloxacin","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"250 mg/1"}],"marketingCategory":"ANDA"},{"route":["OPHTHALMIC"],"labeler":"Advanced Rx of Tennessee, LLC","brandName":"ciprofloxacin","packaging":[{"ndc":"80425-0499-1","description":"1 BOTTLE, PLASTIC in 1 CARTON (80425-0499-1)  / 5 mL in 1 BOTTLE, PLASTIC","marketingStartDate":"20250320"}],"dosageForm":"SOLUTION","genericName":"Ciprofloxacin","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"3 mg/mL"}],"marketingCategory":"ANDA"},{"route":[],"labeler":"Aurobindo Pharma Limited","brandName":"","packaging":[{"ndc":"59651-976-39","description":"3000 TABLET, FILM COATED in 1 BAG (59651-976-39)","marketingStartDate":"27-MAR-25"}],"dosageForm":"TABLET, FILM COATED","genericName":"Ciprofloxacin Hydrochloride","productType":"DRUG FOR FURTHER PROCESSING","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"250 mg/1"}],"marketingCategory":"DRUG FOR FURTHER PROCESSING"},{"route":["ORAL"],"labeler":"NuCare Pharmaceuticals,Inc.","brandName":"Ciprofloxacin","packaging":[{"ndc":"68071-2404-2","description":"2 TABLET, COATED in 1 BOTTLE (68071-2404-2)","marketingStartDate":"20210521"},{"ndc":"68071-2404-4","description":"4 TABLET, COATED in 1 BOTTLE (68071-2404-4)","marketingStartDate":"20210521"},{"ndc":"68071-2404-6","description":"6 TABLET, COATED in 1 BOTTLE (68071-2404-6)","marketingStartDate":"20210521"}],"dosageForm":"TABLET, COATED","genericName":"Ciprofloxacin","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"500 mg/1"}],"marketingCategory":"ANDA"},{"route":["ORAL"],"labeler":"NuCare Pharmaceuticals, Inc.","brandName":"ciprofloxacin","packaging":[{"ndc":"66267-716-02","description":"2 TABLET in 1 BOTTLE (66267-716-02)","marketingStartDate":"20161230"},{"ndc":"66267-716-04","description":"4 TABLET in 1 BOTTLE (66267-716-04)","marketingStartDate":"20161230"},{"ndc":"66267-716-06","description":"6 TABLET in 1 BOTTLE (66267-716-06)","marketingStartDate":"20161230"}],"dosageForm":"TABLET","genericName":"ciprofloxacin","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"500 mg/1"}],"marketingCategory":"ANDA"},{"route":["ORAL"],"labeler":"Yiling Pharmaceutical, Inc.","brandName":"Ciprofloxacin","packaging":[{"ndc":"69117-0008-1","description":"100 TABLET, COATED in 1 BOTTLE (69117-0008-1)","marketingStartDate":"20190713"},{"ndc":"69117-0008-2","description":"500 TABLET, COATED in 1 BOTTLE (69117-0008-2)","marketingStartDate":"20190713"}],"dosageForm":"TABLET, COATED","genericName":"Ciprofloxacin Tablets","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"250 mg/1"}],"marketingCategory":"ANDA"},{"route":["AURICULAR (OTIC)"],"labeler":"Sandoz Inc","brandName":"Ciprofloxacin and Dexamethasone","packaging":[{"ndc":"0781-6186-67","description":"1 BOTTLE, DROPPER in 1 CARTON (0781-6186-67)  / 7.5 mL in 1 BOTTLE, DROPPER","marketingStartDate":"20200810"}],"dosageForm":"SUSPENSION/ DROPS","genericName":"ciprofloxacin and dexamethasone","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"3 mg/mL"},{"name":"DEXAMETHASONE","strength":"1 mg/mL"}],"marketingCategory":"NDA AUTHORIZED GENERIC"},{"route":["ORAL"],"labeler":"PD-Rx Pharmaceuticals, Inc.","brandName":"ciprofloxacin","packaging":[{"ndc":"43063-410-06","description":"6 TABLET in 1 BOTTLE, PLASTIC (43063-410-06)","marketingStartDate":"20120123"},{"ndc":"43063-410-10","description":"10 TABLET in 1 BOTTLE, PLASTIC (43063-410-10)","marketingStartDate":"20170301"},{"ndc":"43063-410-12","description":"12 TABLET in 1 BOTTLE, PLASTIC (43063-410-12)","marketingStartDate":"20121206"},{"ndc":"43063-410-14","description":"14 TABLET in 1 BOTTLE, PLASTIC (43063-410-14)","marketingStartDate":"20130208"},{"ndc":"43063-410-20","description":"20 TABLET in 1 BOTTLE, PLASTIC (43063-410-20)","marketingStartDate":"20140506"}],"dosageForm":"TABLET","genericName":"ciprofloxacin","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"250 mg/1"}],"marketingCategory":"ANDA"},{"route":["ORAL"],"labeler":"Yiling Pharmaceutical, Inc.","brandName":"Ciprofloxacin","packaging":[{"ndc":"69117-0009-1","description":"500 TABLET, COATED in 1 BOTTLE (69117-0009-1)","marketingStartDate":"20190713"},{"ndc":"69117-0009-2","description":"100 TABLET, COATED in 1 BOTTLE (69117-0009-2)","marketingStartDate":"20190713"}],"dosageForm":"TABLET, COATED","genericName":"Ciprofloxacin Tablets","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"500 mg/1"}],"marketingCategory":"ANDA"},{"route":["ORAL"],"labeler":"Aurobindo Pharma Limited","brandName":"Ciprofloxacin","packaging":[{"ndc":"59651-873-50","description":"50 TABLET, FILM COATED in 1 BOTTLE (59651-873-50)","marketingStartDate":"20240209"}],"dosageForm":"TABLET, FILM COATED","genericName":"Ciprofloxacin Hydrochloride","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"750 mg/1"}],"marketingCategory":"ANDA"},{"route":["ORAL"],"labeler":"Denton Pharma, Inc. DBA Northwind Pharmaceuticals","brandName":"Ciprofloxacin","packaging":[{"ndc":"70934-965-06","description":"6 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (70934-965-06)","marketingStartDate":"20220502"},{"ndc":"70934-965-14","description":"14 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (70934-965-14)","marketingStartDate":"20220502"},{"ndc":"70934-965-20","description":"20 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (70934-965-20)","marketingStartDate":"20220502"},{"ndc":"70934-965-30","description":"30 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (70934-965-30)","marketingStartDate":"20220516"},{"ndc":"70934-965-60","description":"60 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (70934-965-60)","marketingStartDate":"20220609"}],"dosageForm":"TABLET, FILM COATED","genericName":"Ciprofloxacin Hydrochloride","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"500 mg/1"}],"marketingCategory":"ANDA"},{"route":["ORAL"],"labeler":"direct rx","brandName":"CIPROFLOXACIN","packaging":[{"ndc":"72189-242-10","description":"10 TABLET, FILM COATED in 1 BOTTLE (72189-242-10)","marketingStartDate":"20210723"},{"ndc":"72189-242-20","description":"20 TABLET, FILM COATED in 1 BOTTLE (72189-242-20)","marketingStartDate":"20210723"}],"dosageForm":"TABLET, FILM COATED","genericName":"CIPROFLOXACIN","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"500 mg/1"}],"marketingCategory":"ANDA"},{"route":["ORAL"],"labeler":"PD-Rx Pharmaceuticals, Inc.","brandName":"Ciprofloxacin","packaging":[{"ndc":"72789-368-14","description":"14 TABLET, FILM COATED in 1 BOTTLE, PLASTIC (72789-368-14)","marketingStartDate":"20231211"}],"dosageForm":"TABLET, FILM COATED","genericName":"Ciprofloxacin Hydrochloride","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"500 mg/1"}],"marketingCategory":"ANDA"},{"route":[],"labeler":"Aurobindo Pharma Limited","brandName":"","packaging":[{"ndc":"59651-977-15","description":"1500 TABLET, FILM COATED in 1 BAG (59651-977-15)","marketingStartDate":"27-MAR-25"}],"dosageForm":"TABLET, FILM COATED","genericName":"Ciprofloxacin Hydrochloride","productType":"DRUG FOR FURTHER PROCESSING","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"500 mg/1"}],"marketingCategory":"DRUG FOR FURTHER PROCESSING"},{"route":[],"labeler":"Aurobindo Pharma Limited","brandName":"","packaging":[{"ndc":"59651-978-99","description":"1000 TABLET, FILM COATED in 1 BAG (59651-978-99)","marketingStartDate":"27-MAR-25"}],"dosageForm":"TABLET, FILM COATED","genericName":"Ciprofloxacin Hydrochloride","productType":"DRUG FOR FURTHER PROCESSING","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"750 mg/1"}],"marketingCategory":"DRUG FOR FURTHER PROCESSING"},{"route":["ORAL"],"labeler":"Aurobindo Pharma Limited","brandName":"Ciprofloxacin","packaging":[{"ndc":"59651-866-01","description":"100 TABLET, FILM COATED in 1 BOTTLE (59651-866-01)","marketingStartDate":"20240209"}],"dosageForm":"TABLET, FILM COATED","genericName":"Ciprofloxacin Hydrochloride","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"250 mg/1"}],"marketingCategory":"ANDA"},{"route":["ORAL"],"labeler":"Bryant Ranch Prepack","brandName":"Ciprofloxacin","packaging":[{"ndc":"63629-3868-1","description":"20 TABLET, FILM COATED in 1 BOTTLE (63629-3868-1)","marketingStartDate":"20081030"},{"ndc":"63629-3868-2","description":"28 TABLET, FILM COATED in 1 BOTTLE (63629-3868-2)","marketingStartDate":"20090612"},{"ndc":"63629-3868-3","description":"14 TABLET, FILM COATED in 1 BOTTLE (63629-3868-3)","marketingStartDate":"20130423"},{"ndc":"63629-3868-4","description":"30 TABLET, FILM COATED in 1 BOTTLE (63629-3868-4)","marketingStartDate":"20110726"},{"ndc":"63629-3868-5","description":"60 TABLET, FILM COATED in 1 BOTTLE (63629-3868-5)","marketingStartDate":"20101214"},{"ndc":"63629-3868-6","description":"10 TABLET, FILM COATED in 1 BOTTLE (63629-3868-6)","marketingStartDate":"20131203"},{"ndc":"63629-3868-7","description":"90 TABLET, FILM COATED in 1 BOTTLE (63629-3868-7)","marketingStartDate":"20230306"}],"dosageForm":"TABLET, FILM COATED","genericName":"Ciprofloxacin","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"750 mg/1"}],"marketingCategory":"ANDA"},{"route":["ORAL"],"labeler":"Proficient Rx LP","brandName":"Ciprofloxacin","packaging":[{"ndc":"71205-997-00","description":"100 TABLET, FILM COATED in 1 BOTTLE (71205-997-00)","marketingStartDate":"20200325"},{"ndc":"71205-997-10","description":"10 TABLET, FILM COATED in 1 BOTTLE (71205-997-10)","marketingStartDate":"20200325"},{"ndc":"71205-997-14","description":"14 TABLET, FILM COATED in 1 BOTTLE (71205-997-14)","marketingStartDate":"20200325"},{"ndc":"71205-997-20","description":"20 TABLET, FILM COATED in 1 BOTTLE (71205-997-20)","marketingStartDate":"20200325"},{"ndc":"71205-997-30","description":"30 TABLET, FILM COATED in 1 BOTTLE (71205-997-30)","marketingStartDate":"20200325"},{"ndc":"71205-997-55","description":"500 TABLET, FILM COATED in 1 BOTTLE (71205-997-55)","marketingStartDate":"20200325"}],"dosageForm":"TABLET, FILM COATED","genericName":"Ciprofloxacin Hydrochloride","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"500 mg/1"}],"marketingCategory":"ANDA"},{"route":["ORAL"],"labeler":"Aurobindo Pharma Limited","brandName":"Ciprofloxacin","packaging":[{"ndc":"59651-867-01","description":"100 TABLET, FILM COATED in 1 BOTTLE (59651-867-01)","marketingStartDate":"20240209"},{"ndc":"59651-867-05","description":"500 TABLET, FILM COATED in 1 BOTTLE (59651-867-05)","marketingStartDate":"20240209"}],"dosageForm":"TABLET, FILM COATED","genericName":"Ciprofloxacin Hydrochloride","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"500 mg/1"}],"marketingCategory":"ANDA"},{"route":[],"labeler":"Quimica Sintetica S.A.","brandName":"","packaging":[{"ndc":"53069-0690-5","description":"25 kg in 1 DRUM (53069-0690-5)","marketingStartDate":"21-FEB-17"}],"dosageForm":"POWDER","genericName":"Ciprofloxacin hydrochloride compacted","productType":"BULK INGREDIENT","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"1 kg/kg"}],"marketingCategory":"BULK INGREDIENT"},{"route":["ORAL"],"labeler":"Hikma Pharmaceuticals USA Inc.","brandName":"Ciprofloxacin","packaging":[{"ndc":"0143-9927-01","description":"100 TABLET, FILM COATED in 1 BOTTLE (0143-9927-01)","marketingStartDate":"20040609"},{"ndc":"0143-9927-05","description":"500 TABLET, FILM COATED in 1 BOTTLE (0143-9927-05)","marketingStartDate":"20040609"},{"ndc":"0143-9927-30","description":"30 TABLET, FILM COATED in 1 BOTTLE (0143-9927-30)","marketingStartDate":"20040609"}],"dosageForm":"TABLET, FILM COATED","genericName":"Ciprofloxacin","productType":"HUMAN PRESCRIPTION DRUG","activeIngredients":[{"name":"CIPROFLOXACIN HYDROCHLORIDE","strength":"250 mg/1"}],"marketingCategory":"ANDA"}],"safety":{"safetySignals":[{"date":"","signal":"DRUG HYPERSENSITIVITY","source":"FDA FAERS","actionTaken":"6,069 reports"},{"date":"","signal":"PAIN","source":"FDA FAERS","actionTaken":"6,014 reports"},{"date":"","signal":"FATIGUE","source":"FDA FAERS","actionTaken":"5,967 reports"},{"date":"","signal":"DIARRHOEA","source":"FDA FAERS","actionTaken":"5,792 reports"},{"date":"","signal":"NAUSEA","source":"FDA FAERS","actionTaken":"5,768 reports"},{"date":"","signal":"ARTHRALGIA","source":"FDA FAERS","actionTaken":"5,489 reports"},{"date":"","signal":"DRUG INEFFECTIVE","source":"FDA FAERS","actionTaken":"5,008 reports"},{"date":"","signal":"ACUTE KIDNEY INJURY","source":"FDA FAERS","actionTaken":"4,674 reports"},{"date":"","signal":"DYSPNOEA","source":"FDA FAERS","actionTaken":"4,566 reports"},{"date":"","signal":"CHRONIC KIDNEY DISEASE","source":"FDA FAERS","actionTaken":"4,553 reports"},{"date":"","signal":"OFF LABEL USE","source":"FDA FAERS","actionTaken":"4,467 reports"},{"date":"","signal":"VOMITING","source":"FDA FAERS","actionTaken":"4,259 reports"},{"date":"","signal":"PYREXIA","source":"FDA FAERS","actionTaken":"4,209 reports"},{"date":"","signal":"ANXIETY","source":"FDA FAERS","actionTaken":"4,137 reports"},{"date":"","signal":"HEADACHE","source":"FDA FAERS","actionTaken":"4,032 reports"},{"date":"","signal":"PAIN IN EXTREMITY","source":"FDA FAERS","actionTaken":"3,794 reports"},{"date":"","signal":"DIZZINESS","source":"FDA FAERS","actionTaken":"3,584 reports"},{"date":"","signal":"PNEUMONIA","source":"FDA FAERS","actionTaken":"3,514 reports"},{"date":"","signal":"ASTHENIA","source":"FDA FAERS","actionTaken":"3,470 reports"},{"date":"","signal":"RENAL FAILURE","source":"FDA FAERS","actionTaken":"3,433 reports"},{"date":"","signal":"MALAISE","source":"FDA FAERS","actionTaken":"3,429 reports"},{"date":"","signal":"RASH","source":"FDA FAERS","actionTaken":"3,339 reports"},{"date":"","signal":"ABDOMINAL PAIN","source":"FDA FAERS","actionTaken":"3,144 reports"},{"date":"","signal":"DRUG INTERACTION","source":"FDA FAERS","actionTaken":"3,121 reports"},{"date":"","signal":"NEUROPATHY PERIPHERAL","source":"FDA FAERS","actionTaken":"3,081 reports"},{"date":"","signal":"URINARY TRACT INFECTION","source":"FDA FAERS","actionTaken":"2,943 reports"},{"date":"","signal":"MYALGIA","source":"FDA FAERS","actionTaken":"2,843 reports"},{"date":"","signal":"CONDITION AGGRAVATED","source":"FDA FAERS","actionTaken":"2,756 reports"},{"date":"","signal":"DEPRESSION","source":"FDA FAERS","actionTaken":"2,728 reports"},{"date":"","signal":"PARAESTHESIA","source":"FDA FAERS","actionTaken":"2,662 reports"},{"date":"","signal":"WEIGHT DECREASED","source":"FDA FAERS","actionTaken":"2,511 reports"},{"date":"","signal":"INSOMNIA","source":"FDA FAERS","actionTaken":"2,465 reports"},{"date":"","signal":"PRURITUS","source":"FDA FAERS","actionTaken":"2,354 reports"},{"date":"","signal":"BACK PAIN","source":"FDA FAERS","actionTaken":"2,279 reports"},{"date":"","signal":"COUGH","source":"FDA FAERS","actionTaken":"2,270 reports"},{"date":"","signal":"TENDONITIS","source":"FDA FAERS","actionTaken":"2,236 reports"},{"date":"","signal":"HYPOAESTHESIA","source":"FDA FAERS","actionTaken":"2,194 reports"},{"date":"","signal":"GAIT DISTURBANCE","source":"FDA FAERS","actionTaken":"2,162 reports"},{"date":"","signal":"TENDON PAIN","source":"FDA FAERS","actionTaken":"1,997 reports"},{"date":"","signal":"ANAEMIA","source":"FDA FAERS","actionTaken":"1,977 reports"},{"date":"","signal":"DEATH","source":"FDA FAERS","actionTaken":"1,957 reports"},{"date":"","signal":"MUSCULAR WEAKNESS","source":"FDA FAERS","actionTaken":"1,853 reports"},{"date":"","signal":"DECREASED APPETITE","source":"FDA FAERS","actionTaken":"1,847 reports"},{"date":"","signal":"ABDOMINAL PAIN UPPER","source":"FDA FAERS","actionTaken":"1,840 reports"},{"date":"","signal":"CHEST PAIN","source":"FDA FAERS","actionTaken":"1,817 reports"},{"date":"","signal":"CONSTIPATION","source":"FDA FAERS","actionTaken":"1,754 reports"},{"date":"","signal":"FALL","source":"FDA FAERS","actionTaken":"1,715 reports"},{"date":"","signal":"MUSCLE SPASMS","source":"FDA FAERS","actionTaken":"1,699 reports"},{"date":"","signal":"CONFUSIONAL STATE","source":"FDA FAERS","actionTaken":"1,647 reports"},{"date":"","signal":"FEELING ABNORMAL","source":"FDA FAERS","actionTaken":"1,629 reports"}],"drugInteractions":[{"drug":"Theophylline","severity":"","mechanism":"Systemic quinolone administration elevates plasma concentrations","management":"","clinicalEffect":"Increased theophylline levels"},{"drug":"Warfarin and derivatives","severity":"","mechanism":"Systemic quinolone administration enhances anticoagulant effects","management":"","clinicalEffect":"Enhanced oral anticoagulant effects"},{"drug":"Cyclosporine","severity":"","mechanism":"Systemic quinolone administration interferes with metabolism","management":"","clinicalEffect":"Transient elevations in serum creatinine"},{"drug":"Caffeine","severity":"","mechanism":"Systemic quinolone administration interferes with metabolism","management":"","clinicalEffect":"Altered caffeine metabolism"}],"commonSideEffects":[{"effect":"Injection site pain","drugRate":"9.7%","organSystem":"General disorders","placeboRate":"","totalAtRisk":62,"totalAffected":6,"trialsReporting":1},{"effect":"Musculoskeletal procedural complication","drugRate":"6.5%","organSystem":"Injury, poisoning and procedural complications","placeboRate":"","totalAtRisk":62,"totalAffected":4,"trialsReporting":1},{"effect":"Injection site movement impairment","drugRate":"4.8%","organSystem":"General disorders","placeboRate":"","totalAtRisk":62,"totalAffected":3,"trialsReporting":1},{"effect":"Vaccination complication","drugRate":"4.8%","organSystem":"Injury, poisoning and procedural complications","placeboRate":"","totalAtRisk":62,"totalAffected":3,"trialsReporting":1},{"effect":"Nausea","drugRate":"3.2%","organSystem":"Gastrointestinal disorders","placeboRate":"","totalAtRisk":62,"totalAffected":2,"trialsReporting":1},{"effect":"Procedural headache","drugRate":"3.2%","organSystem":"Injury, poisoning and procedural complications","placeboRate":"","totalAtRisk":62,"totalAffected":2,"trialsReporting":1},{"effect":"Injection site induration","drugRate":"3.2%","organSystem":"General disorders","placeboRate":"","totalAtRisk":62,"totalAffected":2,"trialsReporting":1},{"effect":"Vomiting","drugRate":"1.6%","organSystem":"Gastrointestinal disorders","placeboRate":"","totalAtRisk":62,"totalAffected":1,"trialsReporting":1}],"contraindications":["History of hypersensitivity to ciprofloxacin or any component of the medication","History of hypersensitivity to other quinolones"],"specialPopulations":{"Nursing":"Nursing Mothers: It is not known whether topically applied ciprofloxacin is excreted in human milk. However, it is known that orally administered ciprofloxacin is excreted in the milk of lactating rats and oral ciprofloxacin has been reported in human breast milk after a single 500 mg dose. Caution should be exercised when Ciprofloxacin Ophthalmic Solution is administered to a nursing mother.","Geriatric":"Geriatric Use: No overall differences in safety or effectiveness have been observed between elderly and younger patients.","Pediatric":"Pediatric Use: The safety and effectiveness of Ciprofloxacin ophthalmic solution 0.3% have been established in all ages. Use of Ciprofloxacin ophthalmic solution is supported by evidence from adequate and well controlled studies of Ciprofloxacin ophthalmic solution in adults, children and neonates [ see Clinical Studies ]. Although ciprofloxacin and other quinolones cause arthropathy in immature animals after oral administration, topical ocular administration of ciprofloxacin to immature animals"},"seriousAdverseEvents":[{"event":"Gastroenteritis viral","detail":"Infections and infestations. 1 trial(s).","severity":"serious","incidence":"1.6%"},{"event":"Uterine prolapse","detail":"Reproductive system and breast disorders. 1 trial(s).","severity":"serious","incidence":"0.0%"}]},"company":"Alk Abello","patents":[{"applNo":"N207986","source":"FDA Orange Book","status":"Active","expires":"Apr 27, 2030","useCode":"U-1792","territory":"US","drugProduct":false,"patentNumber":"8318817","drugSubstance":false},{"applNo":"N207986","source":"FDA Orange Book","status":"Active","expires":"Apr 21, 2029","useCode":"U-2252","territory":"US","drugProduct":true,"patentNumber":"9603796","drugSubstance":true},{"applNo":"N207986","source":"FDA Orange Book","status":"Active","expires":"Apr 21, 2029","useCode":"U-1793","territory":"US","drugProduct":false,"patentNumber":"9205048","drugSubstance":false},{"applNo":"N207986","source":"FDA Orange Book","status":"Active","expires":"Nov 12, 2037","useCode":"U-2252","territory":"US","drugProduct":false,"patentNumber":"11040004","drugSubstance":false},{"applNo":"N207986","source":"FDA Orange Book","status":"Active","expires":"Nov 27, 2038","useCode":"","territory":"US","drugProduct":true,"patentNumber":"11246863","drugSubstance":false},{"applNo":"N207986","source":"FDA Orange Book","status":"Active","expires":"Apr 21, 2029","useCode":"","territory":"US","drugProduct":true,"patentNumber":"11369566","drugSubstance":false},{"applNo":"N207986","source":"FDA Orange Book","status":"Active","expires":"Jul 1, 2035","useCode":"","territory":"US","drugProduct":true,"patentNumber":"9220796","drugSubstance":false},{"applNo":"N207986","source":"FDA Orange Book","status":"Active","expires":"Dec 11, 2029","useCode":"","territory":"US","drugProduct":true,"patentNumber":"9233068","drugSubstance":false}],"pricing":[{"market":"United States","source":"CMS National Average Drug Acquisition Cost (NADAC)","asOfDate":"2024-01-03","unitCost":"$1.3252/ML","priceType":"NADAC","sourceUrl":"https://data.medicaid.gov/dataset/4j6z-xnwq","annualCost":"$477","description":"CIPROFLOXACIN 0.3% EYE DROP","retrievedDate":"2026-04-07"}],"_sources":{"fdaNDC":{"url":"","method":"api_direct","source":"FDA NDC Directory","rawText":"","confidence":1,"sourceType":"fda_ndc","retrievedAt":"2026-04-19T22:21:09.499769+00:00"},"patents":{"url":"","method":"deterministic","source":"FDA Orange Book + Purple Book","rawText":"","confidence":1,"sourceType":"fda_orange_book","retrievedAt":"2026-04-19T22:21:24.581587+00:00"},"dailyMed":{"url":"","method":"api_direct","source":"DailyMed (NIH/NLM)","rawText":"","confidence":1,"sourceType":"dailymed","retrievedAt":"2026-04-19T22:21:10.318554+00:00"},"aiSummary":{"url":"","method":"ai_extraction","source":"AI Strategic Summary","aiModel":"featherless","rawText":"","confidence":0.9,"sourceType":"ai_extraction","retrievedAt":"2026-04-19T22:21:31.392656+00:00"},"mechanism":{"url":"","method":"ai_extraction","source":"FDA Label + Haiku","rawText":"","confidence":0.95,"sourceType":"fda_label","retrievedAt":"2026-04-20T08:34:43.298024+00:00"},"chemblData":{"url":"https://www.ebi.ac.uk/chembl/compound_report_card/CHEMBL8/","method":"api_direct","source":"ChEMBL (EMBL-EBI)","rawText":"","confidence":1,"sourceType":"chembl","retrievedAt":"2026-04-19T22:21:17.226383+00:00"},"fdaRecalls":{"url":"","method":"api_direct","source":"FDA Enforcement/Recalls","rawText":"","confidence":1,"sourceType":"fda_enforcement","retrievedAt":"2026-04-19T22:21:15.651631+00:00"},"overdosage":{"url":"","method":"deterministic","source":"FDA Label (overdosage)","rawText":"","confidence":1,"sourceType":"fda_label","retrievedAt":"2026-04-19T22:20:46.162953+00:00"},"howSupplied":{"url":"","method":"deterministic","source":"FDA Label (how_supplied)","rawText":"HOW SUPPLIED As a sterile ophthalmic solution: 5 mL in translucent LDPE bottle with insert cap assembly comprising of a tan colored HDPE screw cap over a LDPE nozzle with tamper evident LDPE dust cover sealing the bottle cap. 5 mL – NDC 71205-300-05 STORAGE CONDITIONS Store at 25°C (77°F); excursions permitted 15°C to 30°C (59°F to 86°F) [See USP controlled room temperature]. Retain in carton until contents are used and protect from light. ANIMAL PHARMACOLOGY Ciprofloxacin and related drugs have","confidence":1,"sourceType":"fda_label","retrievedAt":"2026-04-19T22:20:33.447371+00:00"},"trialDetails":{"url":"","method":"deterministic","source":"ClinicalTrials.gov (0 trials with endpoints)","rawText":"","confidence":1,"sourceType":"ctgov_results","retrievedAt":"2026-04-19T22:21:34.310937+00:00"},"drugDescription":{"url":"","method":"ai_extraction","source":"FDA Label (description)","aiModel":"featherless","rawText":"DESCRIPTION Ciprofloxacin Ophthalmic Solution is a synthetic, sterile, multiple dose, antimicrobial for topical ophthalmic use. Ciprofloxacin is a fluoroquinolone antibacterial active against a broad spectrum of gram-positive and gram-negative ocular pathogens. It is available as the monohydrochloride monohydrate salt of 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinoline-carboxylic acid. It is a faint to light yellow crystalline powder with a molecular weight of 385.8. Its em","confidence":0.95,"sourceType":"fda_label","retrievedAt":"2026-04-19T22:20:46.162893+00:00"},"pharmacokinetics":{"url":"","method":"ai_extraction","source":"FDA Label (pharmacokinetics)","aiModel":"featherless","rawText":"CLINICAL PHARMACOLOGY Systemic Absorption: A systemic absorption study was performed in which Ciprofloxacin Ophthalmic Solution was administered in each eye every two hours while awake for two days followed by every four hours while awake for an additional 5 days. The maximum reported plasma concentration of ciprofloxacin was less than 5 ng/mL. The mean concentration was usually less than 2.5 ng/mL. Microbiology : Ciprofloxacin has in vitro activity against a wide range of gram-negative and gram","confidence":0.95,"sourceType":"fda_label","retrievedAt":"2026-04-19T22:20:33.447258+00:00"},"publicationCount":{"url":"","method":"api_direct","source":"PubMed/NCBI","rawText":"","confidence":1,"sourceType":"pubmed","retrievedAt":"2026-04-19T22:21:15.780102+00:00"},"faersTotalReports":{"url":"","method":"api_direct","source":"FDA FAERS","rawText":"","confidence":1,"sourceType":"fda_faers","retrievedAt":"2026-04-19T22:21:15.272708+00:00"},"recentPublications":{"url":"","method":"api_direct","source":"PubMed/NCBI","rawText":"","confidence":1,"sourceType":"pubmed","retrievedAt":"2026-04-19T22:21:16.757115+00:00"},"rxnormFormulations":{"url":"https://rxnav.nlm.nih.gov/REST/drugs.json?name=Ciprofloxacin","method":"api_direct","source":"RxNorm (NIH)","rawText":"","confidence":1,"sourceType":"rxnorm","retrievedAt":"2026-04-19T22:21:09.029296+00:00"},"participantFlowData":{"url":"","method":"deterministic","source":"ClinicalTrials.gov participantFlowModule","rawText":"","confidence":1,"sourceType":"ctgov_results","retrievedAt":"2026-04-19T22:21:34.310813+00:00"},"safety.safetySignals":{"url":"","method":"api_direct","source":"FDA FAERS","rawText":"","confidence":1,"sourceType":"fda_faers","retrievedAt":"2026-04-19T22:21:11.299515+00:00"},"structuredTrialResults":{"url":"","method":"deterministic","source":"ClinicalTrials.gov resultsSection (0 trials)","rawText":"","confidence":1,"sourceType":"ctgov_results","retrievedAt":"2026-04-19T22:21:34.310810+00:00"},"safety.drugInteractions":{"url":"","method":"ai_extraction","source":"FDA Label + AI","aiModel":"featherless","rawText":"","confidence":0.9,"sourceType":"fda_label","retrievedAt":"2026-04-19T22:21:05.171823+00:00"},"safety.commonSideEffects":{"url":"","method":"deterministic","source":"ClinicalTrials.gov (1 trials)","rawText":"","confidence":1,"sourceType":"ctgov_results","retrievedAt":"2026-04-20T08:34:43.430744+00:00"},"safety.contraindications":{"url":"","method":"ai_extraction","source":"FDA Label + AI","aiModel":"featherless","rawText":"","confidence":0.95,"sourceType":"fda_label","retrievedAt":"2026-04-19T22:21:08.902898+00:00"},"safety.specialPopulations":{"url":"","method":"deterministic","source":"FDA Label (special populations)","rawText":"","confidence":1,"sourceType":"fda_label","retrievedAt":"2026-04-19T22:21:05.171916+00:00"},"safety.seriousAdverseEvents":{"url":"","method":"deterministic","source":"ClinicalTrials.gov (0 trials)","rawText":"","confidence":1,"sourceType":"ctgov_results","retrievedAt":"2026-04-19T22:21:34.310783+00:00"}},"allNames":"cipro","dailyMed":[{"url":"https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=355fa56f-d7a8-444e-9dec-8ba1fa4ab0d8","setid":"355fa56f-d7a8-444e-9dec-8ba1fa4ab0d8","title":"CIPROFLOXACIN AND DEXAMETHASONE SUSPENSION/ DROPS [SENTISS PHARMACEUTICALS LLC]"},{"url":"https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=4edc4fda-7834-46cc-a0ed-22f117e6e10b","setid":"4edc4fda-7834-46cc-a0ed-22f117e6e10b","title":"CIPROFLOXACIN (CIPROFOLXACIN) TABLET [REMEDYREPACK INC.]"},{"url":"https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0fac4466-fbe5-49d2-96e3-e3ac2739bd5b","setid":"0fac4466-fbe5-49d2-96e3-e3ac2739bd5b","title":"CIPROFLOXACIN (CIPROFLOXACIN HYDROCHLORIDE) TABLET, FILM COATED [AMERICAN HEALTH PACKAGING]"},{"url":"https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=44b6cefc-7638-4437-95e7-8f239f66a9d4","setid":"44b6cefc-7638-4437-95e7-8f239f66a9d4","title":"CIPROFLOXACIN TABLET, FILM COATED [REMEDYREPACK INC.]"},{"url":"https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=641bad60-9b9e-43ea-936e-5c38f27835b2","setid":"641bad60-9b9e-43ea-936e-5c38f27835b2","title":"CIPROFLOXACIN AND DEXAMETHASONE SUSPENSION/ DROPS [SUN PHARMACEUTICAL INDUSTRIES, INC.]"}],"synonyms":["ciprofloxacin","ciprofloxacin hydrochloride","ciprofloxacillin","ciprofloxacine","ciprofloxacin hydrochloride monohydrate","ciprofloxacin HCl","ciprofloxacin lactate"],"timeline":[{"date":"1987-01-01","type":"neutral","source":"FDA Orange Book","milestone":"Rights transferred from BAYER HLTHCARE to Alk Abello"},{"date":"1987-10-22","type":"positive","source":"DrugCentral","milestone":"FDA approval (Bayer Hlthcare)"},{"date":"1990-12-26","type":"positive","source":"FDA Orange Book","milestone":"Cipro approved — 400MG/40ML (10MG/ML) **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**"},{"date":"1997-09-26","type":"positive","source":"FDA Orange Book","milestone":"Cipro approved — 250MG/5ML"},{"date":"2008-04-21","type":"neutral","source":"FDA Orange Book","milestone":"Generic entry — 10 manufacturers approved"},{"date":"2029-04-21","type":"negative","source":"FDA Orange Book","milestone":"Substance patent 9603796 expires"}],"aiSummary":"Ciprofloxacin ophthalmic solution is a fluoroquinolone antibiotic indicated for corneal ulcers and conjunctivitis caused by susceptible organisms. Systemic absorption is minimal with maximum plasma concentrations less than 5 ng/mL following topical ocular administration. Contraindications include hypersensitivity to ciprofloxacin or other quinolones. Drug interactions are primarily associated with systemic quinolone administration affecting theophylline, warfarin, cyclosporine, and caffeine metabolism.","brandName":"Cipro","ecosystem":[{"indication":"Abdominal abscess","otherDrugs":[{"name":"cefoxitin","slug":"cefoxitin","company":""},{"name":"ceftolozane","slug":"ceftolozane","company":"Cubist Pharms"},{"name":"cilastatin","slug":"cilastatin","company":"Merck"},{"name":"doripenem","slug":"doripenem","company":"Shionogi Inc"}],"globalPrevalence":89000},{"indication":"Acute Moraxella catarrhalis bronchitis","otherDrugs":[{"name":"alatrofloxacin","slug":"alatrofloxacin","company":"Pfizer"},{"name":"cefaclor","slug":"cefaclor","company":""},{"name":"cefdinir","slug":"cefdinir","company":""},{"name":"cefpodoxime proxetil","slug":"cefpodoxime-proxetil","company":""}],"globalPrevalence":null},{"indication":"Acute bacterial bronchitis","otherDrugs":[{"name":"alatrofloxacin","slug":"alatrofloxacin","company":"Pfizer"},{"name":"azithromycin","slug":"azithromycin","company":""},{"name":"cefaclor","slug":"cefaclor","company":""},{"name":"cefixime","slug":"cefixime","company":""}],"globalPrevalence":null},{"indication":"Acute bacterial peritonitis","otherDrugs":[{"name":"ertapenem","slug":"ertapenem","company":"Merck Sharp Dohme"},{"name":"norfloxacin","slug":"norfloxacin","company":""},{"name":"ofloxacin","slug":"ofloxacin","company":""},{"name":"trovafloxacin","slug":"trovafloxacin","company":""}],"globalPrevalence":null},{"indication":"Acute bacterial sinusitis","otherDrugs":[{"name":"alatrofloxacin","slug":"alatrofloxacin","company":"Pfizer"},{"name":"amoxicillin","slug":"amoxicillin","company":"Apothecon"},{"name":"ampicillin","slug":"ampicillin","company":"Wyeth Ayerst"},{"name":"azithromycin","slug":"azithromycin","company":""}],"globalPrevalence":null},{"indication":"Acute gonococcal cervicitis","otherDrugs":[{"name":"alatrofloxacin","slug":"alatrofloxacin","company":"Pfizer"},{"name":"amphotericin B","slug":"amphotericin-b","company":"Apothecon"},{"name":"ampicillin","slug":"ampicillin","company":"Wyeth Ayerst"},{"name":"azithromycin","slug":"azithromycin","company":""}],"globalPrevalence":null},{"indication":"Acute gonococcal urethritis","otherDrugs":[{"name":"alatrofloxacin","slug":"alatrofloxacin","company":"Pfizer"},{"name":"amphotericin B","slug":"amphotericin-b","company":"Apothecon"},{"name":"ampicillin","slug":"ampicillin","company":"Wyeth Ayerst"},{"name":"azithromycin","slug":"azithromycin","company":""}],"globalPrevalence":null},{"indication":"Acute maxillary sinusitis","otherDrugs":[{"name":"cefpodoxime proxetil","slug":"cefpodoxime-proxetil","company":""},{"name":"cefuroxime","slug":"cefuroxime","company":"Covis Injectables"},{"name":"cefuroxime axetil","slug":"cefuroxime-axetil","company":"Glaxosmithkline"},{"name":"clarithromycin","slug":"clarithromycin","company":"Abbvie"}],"globalPrevalence":null}],"mechanism":{"target":"DNA gyrase","novelty":"Follow-on","targets":[{"gene":"TOP2A","source":"DrugCentral","target":"DNA topoisomerase II","protein":"DNA topoisomerase 2-alpha"},{"gene":"TOP2B","source":"DrugCentral","target":"DNA topoisomerase II","protein":"DNA topoisomerase 2-beta"}],"moaClass":"Cytochrome P450 1A2 Inhibitors","modality":"Enzyme inhibitor","drugClass":"Fluoroquinolone","explanation":"Ciprofloxacin is a fluoroquinolone antibiotic that exerts bactericidal activity through interference with DNA gyrase, an essential enzyme required for bacterial DNA synthesis. This mechanism of action results in inhibition of bacterial DNA replication and transcription, leading to cell death. The drug demonstrates in vitro activity against a wide range of gram-negative and gram-positive organisms.","oneSentence":"Ciprofloxacin interferes with bacterial DNA gyrase, inhibiting DNA synthesis.","technicalDetail":"Ciprofloxacin is a broad-spectrum antibacterial agent that inhibits DNA gyrase and topoisomerase IV, enzymes critical for bacterial DNA replication, transcription, repair, and recombination."},"_wikipedia":{"url":"https://en.wikipedia.org/wiki/Ciprofloxacin","title":"Ciprofloxacin","extract":"Ciprofloxacin is a fluoroquinolone antibiotic used to treat a number of bacterial infections. This includes bone and joint infections, intra-abdominal infections, certain types of infectious diarrhea, respiratory tract infections, skin infections, typhoid fever, and urinary tract infections, among others. For some infections it is used in addition to other antibiotics. It can be taken by mouth, as eye drops, as ear drops, or intravenously.","wiki_history":"==History==\nthumb|Ciprofloxacin 250-mg tablets from Ukraine\nThe first members of the quinolone antibacterial class were relatively low-potency drugs such as nalidixic acid, used mainly in the treatment of urinary tract infections owing to their renal excretion and propensity to be concentrated in urine. In 1979, the publication of a patent filed by the pharmaceutical arm of Kyorin Seiyaku Kabushiki Kaisha disclosed the discovery of norfloxacin, and the demonstration that certain structural modifications including the attachment of a fluorine atom to the quinolone ring leads to dramatically enhanced antibacterial potency. In the aftermath of this disclosure, several other pharmaceutical companies initiated research and development programs with the goal of discovering additional antibacterial agents of the fluoroquinolone class.\n\nThe fluoroquinolone program at Bayer focused on examining the effects of very minor changes to the norfloxacin structure. In 1983, the company published in vitro potency data for ciprofloxacin, a fluoroquinolone antibacterial having a chemical structure differing from that of norfloxacin by the presence of a single carbon atom. This small change led to a two- to 10-fold increase in potency against most strains of Gram-negative bacteria. Importantly, this structural change led to a four-fold improvement in activity against the important Gram-negative pathogen Pseudomonas aeruginosa, making ciprofloxacin one of the most potent known drugs for the treatment of this intrinsically antibiotic-resistant pathogen.\n\nThe oral tablet form of ciprofloxacin was approved in October 1987, just one year after the approval of norfloxacin. In 1991, the intravenous formulation was introduced. Ciprofloxacin sales reached a peak of about 2 billion euros in 2001, before Bayer's patent expired in 2004, after which annual sales have averaged around €200 million.\n\nThe name probably originates from the International Scientific Nomenclature: ci- (alteration of cycl-) ","wiki_society_and_culture":"==Society and culture==\n\n===Economics===\nIt is available as a low-cost generic medication. in effect upholding Bayer's agreement with its competitors.\n\n===Available forms===\nCiprofloxacin for systemic administration is available as immediate-release tablets, as extended-release tablets, as an oral suspension, and as a solution for intravenous infusion. It is available for local administration as eye drops and ear drops. It is available in combination with dexamethasone, with celecoxib, with hydrocortisone, and with fluocinolone acetonide.\n\n===Litigation===\nA class action was filed against Bayer AG on behalf of employees of the Brentwood Post Office in Washington, D.C., and workers at the U.S. Capitol, along with employees of American Media, Inc. in Florida and postal workers in general who alleged they developed serious adverse effects from taking ciprofloxacin in the aftermath of the anthrax attacks in 2001. The action alleged Bayer failed to warn class members of the potential side effects of the drug, thereby violating the Pennsylvania Unfair Trade Practices and Consumer Protection Laws. The class action was defeated and the litigation abandoned by the plaintiffs. A similar action was filed in 2003 in New Jersey by four New Jersey postal workers but was withdrawn for lack of grounds, as workers had been informed of the risks of ciprofloxacin when they were given the option of taking the drug."},"chemblData":{"prodrug":0,"chemblId":"CHEMBL8","maxPhase":"4.0","chirality":2,"parenteral":true,"availability":1,"moleculeType":"Small molecule","withdrawnFlag":false,"naturalProduct":0,"blackBoxWarning":1,"oralBioavailable":true},"commercial":{"launchDate":"1987","_launchSource":"DrugCentral (FDA 1987-10-22, BAYER HLTHCARE)"},"fdaRecalls":[{"date":"20130206","reason":"Presence of Foreign Substance(s): A complaint was received for a rubber-like material in a 500 mg Ciprofloxacin tablet.","status":"Terminated","distribution":"GA, AR","classification":"Class II"},{"date":"20241216","reason":"Defective container: Unable to get the solution out of the bottle as the spike of the cap was lodged in the nozzle of the product bottle","status":"Ongoing","distribution":"Nationwide","classification":"Class II"},{"date":"20250813","reason":"Temperature Abuse","status":"Ongoing","distribution":"Product was distributed to one consignee in CA.","classification":"Class II"},{"date":"20250311","reason":"Defective container: Unable to get the solution out of the bottle as the spike of the cap was lodged in the nozzle of the product bottle","status":"Ongoing","distribution":"Nationwide in the U.S","classification":"Class II"},{"date":"20190702","reason":"Lack of Assurance of Sterility","status":"Completed","distribution":"U.S.A. Nationwide","classification":"Class II"},{"date":"20190702","reason":"Lack of Assurance of Sterility","status":"Completed","distribution":"U.S.A. Nationwide","classification":"Class II"},{"date":"20190702","reason":"Lack of Assurance of Sterility","status":"Completed","distribution":"U.S.A. Nationwide","classification":"Class II"},{"date":"20240723","reason":"Defective container: unable to get the solution out of the bottle as the spike of the cap was lodged in the nozzle of the product bottle.","status":"Ongoing","distribution":"U.S. A. Nationwide","classification":"Class II"},{"date":"20220413","reason":"cGMP deviations: Temperature abuse","status":"Terminated","distribution":"USA nationwide.","classification":"Class II"},{"date":"20120309","reason":"Labeling Illegible: Missing Label; The voluntary recall of the aforementioned batch of product is being initiated due to two bottles missing container labels.","status":"Terminated","distribution":"Nationwide","classification":"Class III"}],"overdosage":"OVERDOSAGE A topical overdose of ciprofloxacin Ophthalmic Solution may be flushed from the eye(s) with warm tap water.","references":[{"id":1,"url":"https://drugcentral.org/drugcard/659","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://clinicaltrials.gov/search?intr=Ciprofloxacin","fields":["trials"],"source":"ClinicalTrials.gov"},{"id":3,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=Ciprofloxacin","fields":["publications"],"source":"PubMed/NCBI"},{"id":4,"url":"https://en.wikipedia.org/wiki/Ciprofloxacin","fields":["history","overview"],"source":"Wikipedia"},{"id":5,"url":"https://www.fda.gov/drugs/drug-approvals-and-databases/orange-book-data-files","fields":["patents","exclusivity","genericManufacturers"],"source":"FDA Orange Book"}],"_enrichedAt":"2026-03-30T01:53:36.463291","_validation":{"fieldsValidated":7,"lastValidatedAt":"2026-04-20T08:34:45.560273+00:00","fieldsConflicting":0,"overallConfidence":0.95},"competitors":[{"drugName":"ofloxacin","drugSlug":"ofloxacin","fdaApproval":"1990-12-28","genericCount":20,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"enoxacin","drugSlug":"enoxacin","fdaApproval":"1991-12-31","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"norfloxacin","drugSlug":"norfloxacin","fdaApproval":"1986-10-31","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"lomefloxacin","drugSlug":"lomefloxacin","fdaApproval":"1992-02-21","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"sparfloxacin","drugSlug":"sparfloxacin","fdaApproval":"1996-12-19","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"grepafloxacin","drugSlug":"grepafloxacin","fdaApproval":"1997-11-06","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"levofloxacin","drugSlug":"levofloxacin","fdaApproval":"1996-12-20","genericCount":36,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"trovafloxacin","drugSlug":"trovafloxacin","fdaApproval":"1997-12-18","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"moxifloxacin","drugSlug":"moxifloxacin","fdaApproval":"1999-12-10","patentExpiry":"May 29, 2029","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"gemifloxacin","drugSlug":"gemifloxacin","fdaApproval":"2003-04-04","genericCount":1,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"gatifloxacin","drugSlug":"gatifloxacin","fdaApproval":"2003-03-28","genericCount":6,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"delafloxacin","drugSlug":"delafloxacin","fdaApproval":"2017-06-19","patentExpiry":"Sep 23, 2029","patentStatus":"Patent protected","relationship":"same-class"}],"dataSources":[{"url":"https://data.medicaid.gov/dataset/4j6z-xnwq","name":"CMS National Average Drug Acquisition Cost (NADAC)","fields":["pricing"],"retrievedDate":"2026-04-07"}],"genericName":"ciprofloxacin","howSupplied":"HOW SUPPLIED As a sterile ophthalmic solution: 5 mL in translucent LDPE bottle with insert cap assembly comprising of a tan colored HDPE screw cap over a LDPE nozzle with tamper evident LDPE dust cover sealing the bottle cap. 5 mL – NDC 71205-300-05 STORAGE CONDITIONS Store at 25°C (77°F); excursions permitted 15°C to 30°C (59°F to 86°F) [See USP controlled room temperature]. Retain in carton until contents are used and protect from light. ANIMAL PHARMACOLOGY Ciprofloxacin and related drugs have been shown to cause arthropathy in immature animals of most species tested following oral administration. However, a one month topical ocular study using immature Beagle dogs did not demonstrate any articular lesions. CLINICAL STUDIES Following therapy with Ciprofloxacin ophthalmic solution, 76% of the patients with corneal ulcers and positive bacterial cultures were clinically cured and complete re-epithelialisation occurred in about 92% of the ulcers. In 3 and 7 day multicenter clinical trials, 52% of the patients with conjunctivitis and positive conjunctival cultures were clinically cured and 70-80% had all causative pathogens eradicated by the end of treatment. In a randomized, double-masked, multicenter, parallel-group clinical trial of pediatric patients with bacterial conjunctivitis, between birth and 31 days of age, patients were dosed with Ciprofloxacin ophthalmic solution or another anti-infective agent. Clinical outcomes for the trial demonstrated a clinical cure rate of 80% at Day 9 and a microbiological eradication success rate of 85% at Day 9. Please note that microbiologic eradication does not always correlate with clinical outcome in anti-infective trials. Rx Only Distributed by: Leading Pharma, LLC. Fairfield, NJ07004 Manufactured By: FDC Limited, B-8, MIDC Industrial Area, Waluj, Aurangabad - 431 136, Maharashtra, India Revision: 12/2017 STERILE OPHTHALMIC SOLUTION CIPROFLOXACIN OPHTHALMIC SOLUTION USP 0.3% as base INSTRUCTIONS FOR USE Read this Instruction for Use before you start using Ciprofloxacin ophthalmic solution and each time you get a refill. There may be new information. This information does not take the place of talking to your doctor about your medical condition or your treatment. Use Ciprofloxacin ophthalmic solution as prescribed by your doctor. Ask your doctor if you have questions about how to use Ciprofloxacin ophthalmic solution. Important information: • Ciprofloxacin ophthalmic solution is for use in the eye only. Ciprofloxacin ophthalmic solution should not be injected into the eye. • If you use other medicines in your eye, wait at least 10 minutes between using Ciprofloxacin ophthalmic solution and your other eye medicines. • If you wear contact lenses, remove them before using Ciprofloxacin ophthalmic solution. Wait at least 15 minutes after using Ciprofloxacin ophthalmic solution before placing your contact lenses back in your eyes. • Do not touch your eye, fingers, or other surfaces with the tip of the Ciprofloxacin ophthalmic solution bottle. You may get bacteria on the tip of the bottle that can cause you to get an eye infection. This eye infection can lead to serious eye damage or vision loss. If you think you have gotten bacteria on the tip of the bottle or you have an eye infection, call your doctor right away. • Wash your hands before each use. Before you use a bottle of Ciprofloxacin ophthalmic solution for the first time: • Check the expiration date on the bottle before use. Do not use Ciprofloxacin ophthalmic solution if the expiration date has passed. • Check that the seal on the dust cover is not broken or missing. Do not use the medicine if the seal is broken or missing. Call your doctor or pharmacist. Each time you use Ciprofloxacin ophthalmic solution: Step 1: Turn the dust cover clockwise to break the seal. Step 2: Remove the dust cover and throw it away. Step 3: Turn the tan coloured cap anti-clockwise and remove. Place the cap on a clean flat surface. Step 4: Tilt your head backwards. Step 5: Turn the bottle upside down and place the tip of the bottle close to your eye. Do not touch your eye with the tip. Pull your lower eyelid downward and look up. Gently squeeze the bottle and let 1 drop fall into the space between your lower eyelid and your eye. If a drop misses your eye, repeat Step 5. Step 6: Replace the tan coloured cap back on the bottle and turn it clockwise to close. Step 7: Remove any extra solution from skin around the eyes with a tissue. • If your doctor has told you to use drops in both eyes, repeat Step 5 for your other eye. • The Ciprofloxacin ophthalmic solution bottle tip is made to give a certain amount of medicine in 1 drop. Do not make the opening of the bottle tip bigger or you may get too much Ciprofloxacin ophthalmic solution. • After you use all of the doses of Ciprofloxacin ophthalmic solution that your doctor has prescribed, there will be some medicine left in the bottle. Do not use the extra medicine in the bottle. Throw the bottle away. How should I store Ciprofloxacin ophthalmic solution? • Store at 25°C (77°F); excursions permitted 15°C to 30°C (59°F to 86°F) [See USP controlled room temperature]. • Retain in carton until contents are used and protect from light Keep Ciprofloxacin ophthalmic solution and all medicines out of the reach of children. This Instruction for Use has been approved by the U.S. Food and Drug Administration. Distributed by: Leading Pharma, LLC. Fairfield, NJ07004 Manufactured By: FDC Limited, B-8, MIDC Industrial Area, Waluj, Aurangabad - 431 136, Maharashtra, India Relabeled By: Proficient Rx LP Thousand Oaks, CA 91320 Revision: 12/2017 Fig 1 fig 2 fig 2 fig 4 fig 5 fig 6 fig 7 fig 8","indications":{"approved":[{"name":"Abdominal abscess","source":"DrugCentral","snomedId":75100008,"regulator":"FDA","usPrevalence":null,"globalPrevalence":89000,"prevalenceMethod":"curated","prevalenceSource":"Lancet Infect Dis, 2019 (PMID:31285144)"},{"name":"Acute Moraxella catarrhalis bronchitis","source":"DrugCentral","snomedId":195722003,"regulator":"FDA"},{"name":"Acute bacterial bronchitis","source":"DrugCentral","snomedId":233598009,"regulator":"FDA"},{"name":"Acute bacterial peritonitis","source":"DrugCentral","snomedId":31860008,"regulator":"FDA"},{"name":"Acute bacterial sinusitis","source":"DrugCentral","snomedId":75498004,"regulator":"FDA"},{"name":"Acute gonococcal cervicitis","source":"DrugCentral","snomedId":20943002,"regulator":"FDA"},{"name":"Acute gonococcal urethritis","source":"DrugCentral","snomedId":29864006,"regulator":"FDA"},{"name":"Acute maxillary sinusitis","source":"DrugCentral","snomedId":68272006,"regulator":"FDA"},{"name":"Acute osteomyelitis","source":"DrugCentral","snomedId":409780002,"regulator":"FDA"},{"name":"Anthrax","source":"DrugCentral","snomedId":409498004,"regulator":"FDA"},{"name":"Bacterial Corneal Ulcer Infection","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Bacterial conjunctivitis","source":"DrugCentral","snomedId":128350005,"regulator":"FDA"},{"name":"Bacterial infection due to Klebsiella pneumoniae","source":"DrugCentral","snomedId":186435004,"regulator":"FDA"},{"name":"Bacterial pneumonia","source":"DrugCentral","snomedId":53084003,"regulator":"FDA"},{"name":"Bacterial urinary infection","source":"DrugCentral","snomedId":312124009,"regulator":"FDA"},{"name":"Chancroid","source":"DrugCentral","snomedId":266143009,"regulator":"FDA"},{"name":"Chronic Bacterial Prostatitis","source":"DrugCentral","snomedId":"","regulator":"FDA","eligibility":{"Adult Males":{"age":"18 years and above","sex":"Male","microorganisms":["Escherichia coli","Proteus mirabilis"]}}},{"name":"Citrobacter Urinary Tract Infection","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Complicated Bacterial Peritonitis","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Complicated Bacteroides Peritonitis","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Complicated E. Coli Peritonitis","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Complicated Klebsiella Peritonitis","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Complicated Proteus UTI","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Complicated UTI with Pseudomonas Aeruginosa","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Cystitis","source":"DrugCentral","snomedId":38822007,"regulator":"FDA"},{"name":"Diarrhea due to E. Coli","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"E. Coli Cystitis","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"E. Coli Pyelonephritis","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Enteric campylobacteriosis","source":"DrugCentral","snomedId":18081009,"regulator":"FDA"},{"name":"Enterobacter Osteomyelitis","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Enterobacter Pneumonia","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"EnterobacterJoint Infection","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Enterococcus Complicated UTI","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Enterococcus Urinary Tract Infection","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Escherichia coli urinary tract infection","source":"DrugCentral","snomedId":301011002,"regulator":"FDA"},{"name":"Gram-Negative Aerobic Bacillary Pneumonia","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Haemophilus Parainfluenzae Pneumonia","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Haemophilus influenzae pneumonia","source":"DrugCentral","snomedId":70036007,"regulator":"FDA"},{"name":"Infection due to Enterobacteriaceae","source":"DrugCentral","snomedId":128945009,"regulator":"FDA"},{"name":"Infection due to Escherichia coli","source":"DrugCentral","snomedId":71057007,"regulator":"FDA"},{"name":"Infection due to Pseudomonas aeruginosa","source":"DrugCentral","snomedId":11218009,"regulator":"FDA"},{"name":"Infection due to Staphylococcus aureus","source":"DrugCentral","snomedId":406602003,"regulator":"FDA"},{"name":"Infection of bone","source":"DrugCentral","snomedId":111253001,"regulator":"FDA"},{"name":"Infection of skin AND/OR subcutaneous tissue","source":"DrugCentral","snomedId":19824006,"regulator":"FDA"},{"name":"Infectious diarrheal disease","source":"DrugCentral","snomedId":19213003,"regulator":"FDA"},{"name":"Infectious disease of abdomen","source":"DrugCentral","snomedId":128070006,"regulator":"FDA"},{"name":"Infectious disorder of joint","source":"DrugCentral","snomedId":363162000,"regulator":"FDA"},{"name":"Infective cystitis","source":"DrugCentral","snomedId":236620008,"regulator":"FDA"},{"name":"Infective otitis externa","source":"DrugCentral","snomedId":86981007,"regulator":"FDA"},{"name":"Infective otitis media","source":"DrugCentral","snomedId":312218008,"regulator":"FDA"},{"name":"Klebsiella Nosocomial Pneumonia","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Klebsiella cystitis","source":"DrugCentral","snomedId":60867007,"regulator":"FDA"},{"name":"Lower respiratory tract infection","source":"DrugCentral","snomedId":50417007,"regulator":"FDA"},{"name":"Malignant otitis externa due to Pseudomonas aeruginosa","source":"DrugCentral","snomedId":232230009,"regulator":"FDA"},{"name":"Moraxella Catarrhalis Chronic Bronchitis","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Morganella Morganii Urinary Tract Infection","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Nosocomial Pneumonia due to Haemophilus Influenzae","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Nosocomial pneumonia","source":"DrugCentral","snomedId":425464007,"regulator":"FDA"},{"name":"Otitis externa","source":"DrugCentral","snomedId":3135009,"regulator":"FDA"},{"name":"Pneumonia due to Escherichia coli","source":"DrugCentral","snomedId":51530003,"regulator":"FDA"},{"name":"Pneumonia due to Pseudomonas","source":"DrugCentral","snomedId":41381004,"regulator":"FDA"},{"name":"Pneumonia due to Streptococcus","source":"DrugCentral","snomedId":34020007,"regulator":"FDA"},{"name":"Prostatitis","source":"DrugCentral","snomedId":9713002,"regulator":"FDA"},{"name":"Proteus Prostatitis","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Proteus pneumonia","source":"DrugCentral","snomedId":195888009,"regulator":"FDA"},{"name":"Proteus urinary tract infection","source":"DrugCentral","snomedId":301012009,"regulator":"FDA"},{"name":"Providencia Urinary Tract Infection","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Pseudomonas Aeruginosa Joint Infection","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Pseudomonas Aeruginosa Osteomyelitis","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Pseudomonas Aeruginosa Urinary Tract Infection","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Rhinoscleroma","source":"DrugCentral","snomedId":72409005,"regulator":"FDA"},{"name":"Septicemia due to Escherichia coli","source":"DrugCentral","snomedId":9323009,"regulator":"FDA"},{"name":"Serratia Joint Infection","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Serratia Osteomyelitis","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Serratia Urinary Tract Infection","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Shigellosis","source":"DrugCentral","snomedId":36188001,"regulator":"FDA"},{"name":"Skin and Skin Structure Citrobacter Infection","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Skin and Skin Structure Morganella Morganii Infection","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Skin and Skin Structure Proteus Infection","source":"DrugCentral","snomedId":"","regulator":"FDA","usPrevalence":null,"globalPrevalence":251400000,"prevalenceMethod":"curated","prevalenceSource":"Pathogens, 2024 (PMID:39452777)"},{"name":"Skin and Skin Structure Providencia Infection","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Skin and Skin Structure Pseudomonas Aeruginosa Infection","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Skin and Skin Structure Serratia Infection","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Staphylococcus Aureus Otitis Externa","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Staphylococcus Cystitis","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Staphylococcus Epidermidis Skin and Skin Structure Infection","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Staphylococcus Epidermidis Urinary Tract Infection","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Staphylococcus Saprophyticus Urinary Tract Infection","source":"DrugCentral","snomedId":"","regulator":"FDA"},{"name":"Streptococcus pyogenes infection","source":"DrugCentral","snomedId":302809008,"regulator":"FDA"},{"name":"Typhoid fever","source":"DrugCentral","snomedId":4834000,"regulator":"FDA","usPrevalence":null,"globalPrevalence":2000000000,"prevalenceMethod":"curated","prevalenceSource":"Common symptom, not a disease"},{"name":"Urinary tract infection caused by Klebsiella","source":"DrugCentral","snomedId":369001000119100,"regulator":"FDA"}],"offLabel":[{"name":"Cutaneous anthrax","source":"DrugCentral","drugName":"Ciprofloxacin","evidenceCount":40,"evidenceLevel":"moderate"},{"name":"Diabetic Foot Infection","source":"DrugCentral","drugName":"Ciprofloxacin","evidenceCount":120,"evidenceLevel":"strong"},{"name":"Diverticulitis of gastrointestinal tract","source":"DrugCentral","drugName":"Ciprofloxacin","evidenceCount":3,"evidenceLevel":"emerging"},{"name":"Gastrointestinal anthrax","source":"DrugCentral","drugName":"Ciprofloxacin","evidenceCount":4,"evidenceLevel":"emerging"},{"name":"Inhalational anthrax","source":"DrugCentral","drugName":"Ciprofloxacin","evidenceCount":47,"evidenceLevel":"moderate"},{"name":"Prevention of Meningococcal Meningitis","source":"DrugCentral","drugName":"Ciprofloxacin","evidenceCount":40,"evidenceLevel":"moderate"},{"name":"Salmonella septicemia","source":"DrugCentral","drugName":"Ciprofloxacin","evidenceCount":195,"evidenceLevel":"strong"},{"name":"Traveler's diarrhea","source":"DrugCentral","drugName":"Ciprofloxacin","evidenceCount":178,"evidenceLevel":"strong"},{"name":"Ventilator-acquired pneumonia","source":"DrugCentral","drugName":"Ciprofloxacin","evidenceCount":102,"evidenceLevel":"strong"}],"pipeline":[]},"currentOwner":"Alk Abello","drugCategory":"established","relatedDrugs":[{"drugId":"ofloxacin","brandName":"ofloxacin","genericName":"ofloxacin","approvalYear":"1990","relationship":"same-class"},{"drugId":"enoxacin","brandName":"enoxacin","genericName":"enoxacin","approvalYear":"1991","relationship":"same-class"},{"drugId":"norfloxacin","brandName":"norfloxacin","genericName":"norfloxacin","approvalYear":"1986","relationship":"same-class"},{"drugId":"lomefloxacin","brandName":"lomefloxacin","genericName":"lomefloxacin","approvalYear":"1992","relationship":"same-class"},{"drugId":"sparfloxacin","brandName":"sparfloxacin","genericName":"sparfloxacin","approvalYear":"1996","relationship":"same-class"},{"drugId":"grepafloxacin","brandName":"grepafloxacin","genericName":"grepafloxacin","approvalYear":"1997","relationship":"same-class"},{"drugId":"levofloxacin","brandName":"levofloxacin","genericName":"levofloxacin","approvalYear":"1996","relationship":"same-class"},{"drugId":"trovafloxacin","brandName":"trovafloxacin","genericName":"trovafloxacin","approvalYear":"1997","relationship":"same-class"},{"drugId":"moxifloxacin","brandName":"moxifloxacin","genericName":"moxifloxacin","approvalYear":"1999","relationship":"same-class"},{"drugId":"gemifloxacin","brandName":"gemifloxacin","genericName":"gemifloxacin","approvalYear":"2003","relationship":"same-class"}],"trialDetails":[],"whoEssential":true,"administration":{"route":"Intravenous, Ophthalmic, Auricular (Otic)","formulation":"Injection, Ointment, Solution, Solution/ Drops","formulations":[{"form":"INJECTION","route":"INTRAVENOUS","productName":"Ciprofloxacin"},{"form":"INJECTION, SOLUTION","route":"INTRAVENOUS","productName":"CIPROFLOXACIN"},{"form":"INJECTION, SOLUTION","route":"INTRAVENOUS","productName":"Ciprofloxacin"},{"form":"INJECTION, SOLUTION","route":"INTRAVENOUS","productName":"Ciprofloxacin in Dextrose"},{"form":"INJECTION, SOLUTION, CONCENTRATE","route":"INTRAVENOUS","productName":"Ciprofloxacin"},{"form":"OINTMENT","route":"OPHTHALMIC","productName":"CILOXAN"},{"form":"SOLUTION","route":"AURICULAR (OTIC)","productName":"Ciprofloxacin and Fluocinolone Acetonide"},{"form":"SOLUTION","route":"AURICULAR (OTIC)","productName":"OTOVEL"},{"form":"SOLUTION","route":"OPHTHALMIC","productName":"CIPROFLOXACIN"},{"form":"SOLUTION","route":"OPHTHALMIC","productName":"Ciprofloxacin HCl Ophthalmic"},{"form":"SOLUTION","route":"OPHTHALMIC","productName":"ciprofloxacin"},{"form":"SOLUTION","route":"OPHTHALMIC","productName":"Ciloxan"},{"form":"SOLUTION","route":"OPHTHALMIC","productName":"Ciprofloxacin Hydrochloride"},{"form":"SOLUTION","route":"OPHTHALMIC","productName":"CIPROFLOXACIN HYDROCHLORIDE"},{"form":"SOLUTION/ DROPS","route":"AURICULAR (OTIC)","productName":"CETRAXAL"}]},"_patentsChecked":true,"crossReferences":{"NUI":"N0000147503","MMSL":"31644","NDDF":"002882","UNII":"5E8K9I0O4U","VUID":"4019307","CHEBI":"CHEBI:100241","VANDF":"4019306","INN_ID":"5446","RXNORM":"235851","UMLSCUI":"C0008809","chemblId":"CHEMBL8","ChEMBL_ID":"CHEMBL8","KEGG_DRUG":"D00186","DRUGBANK_ID":"DB00537","PDB_CHEM_ID":" CPF","PUBCHEM_CID":"2764","SNOMEDCT_US":"20450009","IUPHAR_LIGAND_ID":"10902","SECONDARY_CAS_RN":"86393-32-0","MESH_DESCRIPTOR_UI":"D002939"},"drugDescription":{"pH":"approximately 4.5","structure":"1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinoline-carboxylic acid monohydrochloride monohydrate","appearance":"faint to light yellow crystalline powder","composition":"Active: ciprofloxacin HCl 3.5 mg equivalent to 3 mg base. Preservative: benzalkonium chloride 0.006%. Inactives: sodium acetate, acetic acid, mannitol 4.6%, edetate disodium 0.05%, hydrochloric acid and/or sodium hydroxide (to adjust pH), and water for injection.","molecularWeight":"385.8 g/mol","molecularFormula":"C17H18FN3O3•HCl•H2O"},"_enricherVersion":"v2","_offLabelChecked":true,"chemblMechanisms":[{"actionType":"INHIBITOR","targetChemblId":"CHEMBL2311224","mechanismComment":null,"mechanismOfAction":"Bacterial DNA gyrase inhibitor"},{"actionType":"INHIBITOR","targetChemblId":"CHEMBL2363076","mechanismComment":null,"mechanismOfAction":"Topoisomerase IV inhibitor"}],"ownershipHistory":[{"period":"1987-","companyName":"Bayer","relationship":"Original Developer"},{"period":"present","companyName":"Alk Abello","relationship":"Current Owner"}],"pharmacokinetics":{"tmax":"","halfLife":"","linearPK":"","clearance":"","excretion":"","metabolism":"","proteinBinding":"","bioavailability":"","specialPopulations":{"age":"","renal":"","weight":"","hepatic":""},"volumeOfDistribution":""},"publicationCount":37056,"atcClassification":{"source":"DrugCentral","atcCode":"J01MA02","allCodes":["J01MA02","J01RA10","J01RA11","J01RA12","S01AE03","S02AA15","S03AA07"]},"faersTotalReports":94810,"originalDeveloper":"Bayer Hlthcare","faersReportsByYear":[{"time":"19970813","count":1},{"time":"19990119","count":1},{"time":"19990202","count":1},{"time":"19990308","count":1},{"time":"20010404","count":1},{"time":"20020423","count":1},{"time":"20030922","count":2},{"time":"20031013","count":1},{"time":"20040102","count":2},{"time":"20040104","count":1},{"time":"20040106","count":4},{"time":"20040107","count":1},{"time":"20040108","count":2},{"time":"20040109","count":3},{"time":"20040112","count":3},{"time":"20040113","count":6},{"time":"20040114","count":2},{"time":"20040115","count":1},{"time":"20040116","count":5},{"time":"20040119","count":1},{"time":"20040120","count":4},{"time":"20040121","count":5},{"time":"20040122","count":4},{"time":"20040123","count":4},{"time":"20040126","count":3},{"time":"20040127","count":4},{"time":"20040128","count":2},{"time":"20040129","count":3},{"time":"20040130","count":6},{"time":"20040202","count":1},{"time":"20040203","count":2},{"time":"20040204","count":5},{"time":"20040205","count":5},{"time":"20040206","count":6},{"time":"20040209","count":6},{"time":"20040210","count":2},{"time":"20040211","count":3},{"time":"20040212","count":4},{"time":"20040213","count":1},{"time":"20040216","count":2},{"time":"20040217","count":1},{"time":"20040218","count":3},{"time":"20040219","count":1},{"time":"20040220","count":2},{"time":"20040223","count":2},{"time":"20040225","count":5},{"time":"20040226","count":3},{"time":"20040227","count":3},{"time":"20040301","count":5},{"time":"20040302","count":5},{"time":"20040303","count":9},{"time":"20040304","count":6},{"time":"20040305","count":8},{"time":"20040308","count":3},{"time":"20040309","count":2},{"time":"20040310","count":1},{"time":"20040311","count":2},{"time":"20040312","count":2},{"time":"20040315","count":7},{"time":"20040316","count":2},{"time":"20040317","count":2},{"time":"20040318","count":4},{"time":"20040319","count":10},{"time":"20040322","count":10},{"time":"20040323","count":6},{"time":"20040324","count":4},{"time":"20040325","count":5},{"time":"20040326","count":3},{"time":"20040329","count":6},{"time":"20040330","count":4},{"time":"20040331","count":6},{"time":"20040401","count":2},{"time":"20040402","count":4},{"time":"20040405","count":6},{"time":"20040406","count":3},{"time":"20040407","count":4},{"time":"20040408","count":4},{"time":"20040409","count":5},{"time":"20040412","count":5},{"time":"20040413","count":3},{"time":"20040414","count":2},{"time":"20040415","count":4},{"time":"20040416","count":5},{"time":"20040419","count":9},{"time":"20040420","count":4},{"time":"20040421","count":4},{"time":"20040422","count":1},{"time":"20040423","count":4},{"time":"20040426","count":3},{"time":"20040427","count":4},{"time":"20040428","count":7},{"time":"20040429","count":2},{"time":"20040430","count":2},{"time":"20040503","count":9},{"time":"20040504","count":4},{"time":"20040505","count":2},{"time":"20040506","count":1},{"time":"20040507","count":6},{"time":"20040510","count":4},{"time":"20040511","count":3},{"time":"20040512","count":8},{"time":"20040513","count":4},{"time":"20040514","count":3},{"time":"20040517","count":3},{"time":"20040518","count":5},{"time":"20040519","count":3},{"time":"20040520","count":5},{"time":"20040521","count":11},{"time":"20040524","count":3},{"time":"20040525","count":2},{"time":"20040526","count":5},{"time":"20040527","count":3},{"time":"20040528","count":6},{"time":"20040601","count":4},{"time":"20040602","count":12},{"time":"20040603","count":2},{"time":"20040607","count":4},{"time":"20040608","count":1},{"time":"20040609","count":5},{"time":"20040610","count":2},{"time":"20040611","count":7},{"time":"20040614","count":4},{"time":"20040615","count":1},{"time":"20040616","count":4},{"time":"20040617","count":2},{"time":"20040618","count":7},{"time":"20040621","count":7},{"time":"20040622","count":2},{"time":"20040623","count":4},{"time":"20040624","count":1},{"time":"20040625","count":1},{"time":"20040628","count":3},{"time":"20040630","count":6},{"time":"20040701","count":4},{"time":"20040702","count":5},{"time":"20040707","count":6},{"time":"20040708","count":6},{"time":"20040709","count":6},{"time":"20040712","count":3},{"time":"20040713","count":4},{"time":"20040714","count":4},{"time":"20040715","count":1},{"time":"20040716","count":5},{"time":"20040719","count":9},{"time":"20040720","count":1},{"time":"20040721","count":8},{"time":"20040722","count":3},{"time":"20040723","count":7},{"time":"20040726","count":9},{"time":"20040727","count":7},{"time":"20040728","count":2},{"time":"20040729","count":1},{"time":"20040730","count":1},{"time":"20040802","count":6},{"time":"20040803","count":5},{"time":"20040804","count":2},{"time":"20040805","count":3},{"time":"20040806","count":4},{"time":"20040809","count":5},{"time":"20040810","count":1},{"time":"20040811","count":2},{"time":"20040812","count":5},{"time":"20040813","count":3},{"time":"20040816","count":4},{"time":"20040817","count":2},{"time":"20040818","count":3},{"time":"20040819","count":4},{"time":"20040820","count":4},{"time":"20040823","count":5},{"time":"20040824","count":2},{"time":"20040825","count":2},{"time":"20040826","count":4},{"time":"20040827","count":6},{"time":"20040830","count":2},{"time":"20040831","count":10},{"time":"20040901","count":8},{"time":"20040902","count":4},{"time":"20040903","count":2},{"time":"20040907","count":4},{"time":"20040908","count":4},{"time":"20040909","count":2},{"time":"20040910","count":7},{"time":"20040913","count":4},{"time":"20040914","count":6},{"time":"20040915","count":6},{"time":"20040916","count":7},{"time":"20040917","count":6},{"time":"20040920","count":3},{"time":"20040921","count":9},{"time":"20040922","count":4},{"time":"20040923","count":6},{"time":"20040924","count":3},{"time":"20040927","count":5},{"time":"20040928","count":6},{"time":"20040929","count":2},{"time":"20040930","count":5},{"time":"20041001","count":4},{"time":"20041004","count":6},{"time":"20041005","count":5},{"time":"20041006","count":6},{"time":"20041007","count":3},{"time":"20041008","count":7},{"time":"20041011","count":2},{"time":"20041012","count":5},{"time":"20041013","count":2},{"time":"20041014","count":1},{"time":"20041015","count":4},{"time":"20041018","count":2},{"time":"20041019","count":1},{"time":"20041020","count":3},{"time":"20041021","count":7},{"time":"20041025","count":23},{"time":"20041026","count":1},{"time":"20041027","count":9},{"time":"20041028","count":4},{"time":"20041029","count":5},{"time":"20041101","count":6},{"time":"20041102","count":8},{"time":"20041103","count":3},{"time":"20041104","count":4},{"time":"20041105","count":3},{"time":"20041108","count":1},{"time":"20041109","count":2},{"time":"20041110","count":3},{"time":"20041111","count":1},{"time":"20041112","count":4},{"time":"20041116","count":1},{"time":"20041117","count":4},{"time":"20041118","count":5},{"time":"20041119","count":2},{"time":"20041122","count":6},{"time":"20041123","count":4},{"time":"20041124","count":3},{"time":"20041126","count":4},{"time":"20041129","count":4},{"time":"20041130","count":8},{"time":"20041201","count":5},{"time":"20041202","count":1},{"time":"20041203","count":1},{"time":"20041206","count":4},{"time":"20041207","count":3},{"time":"20041208","count":4},{"time":"20041209","count":4},{"time":"20041210","count":6},{"time":"20041213","count":1},{"time":"20041214","count":6},{"time":"20041215","count":4},{"time":"20041216","count":6},{"time":"20041217","count":5},{"time":"20041220","count":2},{"time":"20041221","count":2},{"time":"20041222","count":3},{"time":"20041223","count":4},{"time":"20041224","count":1},{"time":"20041227","count":5},{"time":"20041228","count":3},{"time":"20041229","count":1},{"time":"20041230","count":3},{"time":"20050103","count":4},{"time":"20050104","count":3},{"time":"20050105","count":2},{"time":"20050106","count":4},{"time":"20050107","count":3},{"time":"20050110","count":6},{"time":"20050111","count":10},{"time":"20050112","count":44},{"time":"20050113","count":1},{"time":"20050114","count":6},{"time":"20050118","count":6},{"time":"20050119","count":6},{"time":"20050120","count":2},{"time":"20050121","count":10},{"time":"20050124","count":1},{"time":"20050125","count":6},{"time":"20050126","count":4},{"time":"20050127","count":3},{"time":"20050128","count":2},{"time":"20050131","count":4},{"time":"20050201","count":4},{"time":"20050202","count":3},{"time":"20050203","count":3},{"time":"20050204","count":2},{"time":"20050207","count":3},{"time":"20050208","count":7},{"time":"20050209","count":1},{"time":"20050210","count":2},{"time":"20050211","count":3},{"time":"20050214","count":9},{"time":"20050215","count":3},{"time":"20050216","count":4},{"time":"20050217","count":3},{"time":"20050218","count":2},{"time":"20050221","count":2},{"time":"20050222","count":6},{"time":"20050223","count":7},{"time":"20050224","count":6},{"time":"20050225","count":7},{"time":"20050228","count":3},{"time":"20050301","count":3},{"time":"20050302","count":4},{"time":"20050303","count":3},{"time":"20050304","count":2},{"time":"20050307","count":3},{"time":"20050308","count":2},{"time":"20050309","count":6},{"time":"20050310","count":3},{"time":"20050311","count":2},{"time":"20050314","count":2},{"time":"20050315","count":3},{"time":"20050316","count":2},{"time":"20050317","count":3},{"time":"20050318","count":3},{"time":"20050321","count":6},{"time":"20050322","count":2},{"time":"20050323","count":1},{"time":"20050324","count":2},{"time":"20050325","count":5},{"time":"20050328","count":3},{"time":"20050329","count":4},{"time":"20050330","count":5},{"time":"20050331","count":7},{"time":"20050401","count":2},{"time":"20050404","count":3},{"time":"20050405","count":7},{"time":"20050406","count":4},{"time":"20050407","count":3},{"time":"20050408","count":4},{"time":"20050411","count":3},{"time":"20050412","count":5},{"time":"20050413","count":2},{"time":"20050414","count":6},{"time":"20050415","count":1},{"time":"20050418","count":5},{"time":"20050419","count":3},{"time":"20050420","count":6},{"time":"20050421","count":3},{"time":"20050422","count":3},{"time":"20050425","count":5},{"time":"20050426","count":4},{"time":"20050427","count":5},{"time":"20050428","count":4},{"time":"20050429","count":8},{"time":"20050502","count":3},{"time":"20050503","count":8},{"time":"20050505","count":3},{"time":"20050506","count":2},{"time":"20050509","count":2},{"time":"20050510","count":4},{"time":"20050511","count":6},{"time":"20050512","count":4},{"time":"20050513","count":8},{"time":"20050516","count":2},{"time":"20050517","count":7},{"time":"20050518","count":3},{"time":"20050519","count":4},{"time":"20050520","count":4},{"time":"20050523","count":4},{"time":"20050524","count":2},{"time":"20050525","count":9},{"time":"20050526","count":5},{"time":"20050527","count":10},{"time":"20050531","count":11},{"time":"20050602","count":5},{"time":"20050603","count":1},{"time":"20050606","count":10},{"time":"20050607","count":2},{"time":"20050608","count":1},{"time":"20050609","count":3},{"time":"20050610","count":2},{"time":"20050613","count":4},{"time":"20050614","count":3},{"time":"20050616","count":1},{"time":"20050617","count":4},{"time":"20050620","count":2},{"time":"20050621","count":3},{"time":"20050622","count":5},{"time":"20050623","count":2},{"time":"20050624","count":2},{"time":"20050627","count":3},{"time":"20050628","count":3},{"time":"20050629","count":7},{"time":"20050630","count":9},{"time":"20050701","count":2},{"time":"20050705","count":7},{"time":"20050706","count":10},{"time":"20050707","count":1},{"time":"20050708","count":5},{"time":"20050711","count":12},{"time":"20050712","count":5},{"time":"20050713","count":5},{"time":"20050714","count":1},{"time":"20050715","count":5},{"time":"20050718","count":1},{"time":"20050719","count":14},{"time":"20050720","count":3},{"time":"20050721","count":7},{"time":"20050722","count":6},{"time":"20050725","count":4},{"time":"20050726","count":7},{"time":"20050727","count":6},{"time":"20050728","count":6},{"time":"20050729","count":6},{"time":"20050801","count":4},{"time":"20050802","count":4},{"time":"20050803","count":1},{"time":"20050804","count":2},{"time":"20050805","count":2},{"time":"20050808","count":3},{"time":"20050809","count":7},{"time":"20050810","count":1},{"time":"20050811","count":2},{"time":"20050812","count":1},{"time":"20050815","count":4},{"time":"20050816","count":2},{"time":"20050817","count":3},{"time":"20050818","count":2},{"time":"20050819","count":2},{"time":"20050822","count":8},{"time":"20050823","count":4},{"time":"20050824","count":2},{"time":"20050825","count":2},{"time":"20050826","count":2},{"time":"20050829","count":2},{"time":"20050830","count":4},{"time":"20050831","count":3},{"time":"20050901","count":1},{"time":"20050902","count":2},{"time":"20050906","count":6},{"time":"20050907","count":3},{"time":"20050908","count":1},{"time":"20050909","count":1},{"time":"20050912","count":2},{"time":"20050913","count":2},{"time":"20050914","count":8},{"time":"20050915","count":3},{"time":"20050916","count":2},{"time":"20050919","count":3},{"time":"20050920","count":7},{"time":"20050921","count":2},{"time":"20050922","count":2},{"time":"20050923","count":6},{"time":"20050926","count":5},{"time":"20050927","count":4},{"time":"20050928","count":2},{"time":"20050929","count":4},{"time":"20050930","count":7},{"time":"20051003","count":11},{"time":"20051004","count":6},{"time":"20051005","count":8},{"time":"20051006","count":1},{"time":"20051007","count":2},{"time":"20051010","count":1},{"time":"20051011","count":7},{"time":"20051012","count":7},{"time":"20051013","count":12},{"time":"20051014","count":5},{"time":"20051017","count":3},{"time":"20051018","count":4},{"time":"20051019","count":4},{"time":"20051020","count":7},{"time":"20051021","count":4},{"time":"20051024","count":3},{"time":"20051025","count":2},{"time":"20051026","count":6},{"time":"20051027","count":3},{"time":"20051028","count":8},{"time":"20051031","count":9},{"time":"20051101","count":5},{"time":"20051102","count":1},{"time":"20051103","count":3},{"time":"20051104","count":7},{"time":"20051107","count":4},{"time":"20051108","count":6},{"time":"20051109","count":4},{"time":"20051110","count":4},{"time":"20051111","count":3},{"time":"20051114","count":4},{"time":"20051115","count":1},{"time":"20051116","count":3},{"time":"20051117","count":4},{"time":"20051118","count":6},{"time":"20051121","count":9},{"time":"20051123","count":7},{"time":"20051125","count":4},{"time":"20051128","count":11},{"time":"20051129","count":14},{"time":"20051130","count":27},{"time":"20051201","count":13},{"time":"20051202","count":3},{"time":"20051205","count":2},{"time":"20051206","count":4},{"time":"20051207","count":2},{"time":"20051208","count":7},{"time":"20051209","count":3},{"time":"20051212","count":6},{"time":"20051213","count":4},{"time":"20051214","count":2},{"time":"20051215","count":4},{"time":"20051216","count":5},{"time":"20051219","count":4},{"time":"20051220","count":5},{"time":"20051221","count":9},{"time":"20051222","count":11},{"time":"20051223","count":3},{"time":"20051227","count":1},{"time":"20051228","count":3},{"time":"20051229","count":3},{"time":"20051230","count":3},{"time":"20060103","count":5},{"time":"20060104","count":3},{"time":"20060105","count":5},{"time":"20060106","count":8},{"time":"20060109","count":7},{"time":"20060110","count":6},{"time":"20060111","count":4},{"time":"20060112","count":1},{"time":"20060113","count":3},{"time":"20060117","count":7},{"time":"20060118","count":7},{"time":"20060119","count":2},{"time":"20060123","count":3},{"time":"20060124","count":4},{"time":"20060125","count":11},{"time":"20060126","count":7},{"time":"20060127","count":14},{"time":"20060130","count":12},{"time":"20060131","count":2},{"time":"20060201","count":6},{"time":"20060202","count":1},{"time":"20060203","count":6},{"time":"20060206","count":7},{"time":"20060207","count":6},{"time":"20060208","count":9},{"time":"20060209","count":3},{"time":"20060210","count":4},{"time":"20060213","count":4},{"time":"20060214","count":11},{"time":"20060215","count":4},{"time":"20060216","count":10},{"time":"20060217","count":19},{"time":"20060221","count":11},{"time":"20060222","count":4},{"time":"20060223","count":7},{"time":"20060224","count":3},{"time":"20060227","count":10},{"time":"20060228","count":7},{"time":"20060301","count":6},{"time":"20060302","count":5},{"time":"20060303","count":3},{"time":"20060306","count":4},{"time":"20060307","count":4},{"time":"20060308","count":2},{"time":"20060309","count":5},{"time":"20060310","count":3},{"time":"20060313","count":3},{"time":"20060314","count":4},{"time":"20060315","count":2},{"time":"20060316","count":6},{"time":"20060317","count":2},{"time":"20060321","count":2},{"time":"20060322","count":1},{"time":"20060323","count":3},{"time":"20060324","count":4},{"time":"20060327","count":3},{"time":"20060328","count":1},{"time":"20060329","count":6},{"time":"20060330","count":3},{"time":"20060331","count":5},{"time":"20060403","count":10},{"time":"20060404","count":6},{"time":"20060405","count":5},{"time":"20060406","count":3},{"time":"20060407","count":4},{"time":"20060410","count":12},{"time":"20060411","count":8},{"time":"20060412","count":5},{"time":"20060413","count":2},{"time":"20060414","count":6},{"time":"20060417","count":1},{"time":"20060418","count":4},{"time":"20060419","count":6},{"time":"20060420","count":5},{"time":"20060421","count":16},{"time":"20060424","count":10},{"time":"20060425","count":6},{"time":"20060426","count":5},{"time":"20060427","count":8},{"time":"20060428","count":8},{"time":"20060501","count":6},{"time":"20060502","count":4},{"time":"20060503","count":5},{"time":"20060504","count":6},{"time":"20060505","count":4},{"time":"20060508","count":8},{"time":"20060509","count":5},{"time":"20060510","count":6},{"time":"20060511","count":8},{"time":"20060512","count":9},{"time":"20060515","count":11},{"time":"20060516","count":9},{"time":"20060517","count":8},{"time":"20060518","count":6},{"time":"20060519","count":5},{"time":"20060522","count":5},{"time":"20060523","count":9},{"time":"20060524","count":7},{"time":"20060525","count":1},{"time":"20060526","count":11},{"time":"20060530","count":6},{"time":"20060531","count":10},{"time":"20060601","count":3},{"time":"20060602","count":2},{"time":"20060605","count":2},{"time":"20060606","count":2},{"time":"20060607","count":6},{"time":"20060608","count":1},{"time":"20060609","count":3},{"time":"20060612","count":1},{"time":"20060613","count":2},{"time":"20060614","count":3},{"time":"20060615","count":6},{"time":"20060616","count":2},{"time":"20060619","count":4},{"time":"20060620","count":6},{"time":"20060622","count":2},{"time":"20060623","count":1},{"time":"20060626","count":3},{"time":"20060627","count":3},{"time":"20060628","count":2},{"time":"20060629","count":5},{"time":"20060630","count":3},{"time":"20060703","count":7},{"time":"20060705","count":2},{"time":"20060706","count":2},{"time":"20060707","count":5},{"time":"20060710","count":6},{"time":"20060711","count":4},{"time":"20060712","count":5},{"time":"20060713","count":2},{"time":"20060714","count":1},{"time":"20060718","count":4},{"time":"20060719","count":7},{"time":"20060720","count":4},{"time":"20060721","count":7},{"time":"20060724","count":6},{"time":"20060725","count":5},{"time":"20060726","count":8},{"time":"20060727","count":8},{"time":"20060728","count":4},{"time":"20060731","count":7},{"time":"20060801","count":9},{"time":"20060802","count":10},{"time":"20060803","count":5},{"time":"20060804","count":4},{"time":"20060807","count":5},{"time":"20060808","count":6},{"time":"20060810","count":9},{"time":"20060811","count":3},{"time":"20060814","count":4},{"time":"20060816","count":4},{"time":"20060817","count":4},{"time":"20060818","count":3},{"time":"20060821","count":2},{"time":"20060822","count":2},{"time":"20060823","count":8},{"time":"20060824","count":4},{"time":"20060825","count":4},{"time":"20060828","count":10},{"time":"20060829","count":3},{"time":"20060830","count":4},{"time":"20060831","count":6},{"time":"20060901","count":3},{"time":"20060905","count":2},{"time":"20060906","count":4},{"time":"20060907","count":3},{"time":"20060908","count":2},{"time":"20060911","count":8},{"time":"20060912","count":2},{"time":"20060913","count":3},{"time":"20060914","count":3},{"time":"20060915","count":5},{"time":"20060918","count":5},{"time":"20060919","count":2},{"time":"20060920","count":4},{"time":"20060921","count":7},{"time":"20060922","count":4},{"time":"20060925","count":4},{"time":"20060926","count":7},{"time":"20060927","count":4},{"time":"20060928","count":6},{"time":"20061002","count":7},{"time":"20061003","count":6},{"time":"20061004","count":2},{"time":"20061005","count":5},{"time":"20061006","count":42},{"time":"20061009","count":4},{"time":"20061010","count":1},{"time":"20061011","count":5},{"time":"20061012","count":7},{"time":"20061013","count":3},{"time":"20061016","count":9},{"time":"20061017","count":1},{"time":"20061018","count":4},{"time":"20061019","count":3},{"time":"20061020","count":6},{"time":"20061023","count":3},{"time":"20061024","count":4},{"time":"20061025","count":7},{"time":"20061026","count":7},{"time":"20061027","count":2},{"time":"20061030","count":4},{"time":"20061031","count":2},{"time":"20061101","count":2},{"time":"20061102","count":8},{"time":"20061103","count":5},{"time":"20061106","count":5},{"time":"20061107","count":6},{"time":"20061108","count":4},{"time":"20061109","count":6},{"time":"20061110","count":7},{"time":"20061113","count":5},{"time":"20061114","count":10},{"time":"20061115","count":5},{"time":"20061116","count":5},{"time":"20061117","count":3},{"time":"20061120","count":7},{"time":"20061121","count":8},{"time":"20061122","count":3},{"time":"20061124","count":2},{"time":"20061127","count":4},{"time":"20061128","count":7},{"time":"20061129","count":8},{"time":"20061130","count":7},{"time":"20061201","count":8},{"time":"20061204","count":3},{"time":"20061205","count":3},{"time":"20061206","count":8},{"time":"20061207","count":3},{"time":"20061208","count":9},{"time":"20061211","count":5},{"time":"20061212","count":8},{"time":"20061213","count":3},{"time":"20061214","count":6},{"time":"20061215","count":1},{"time":"20061218","count":10},{"time":"20061219","count":7},{"time":"20061220","count":5},{"time":"20061221","count":9},{"time":"20061222","count":11},{"time":"20061226","count":4},{"time":"20061227","count":6},{"time":"20061228","count":7},{"time":"20061229","count":6},{"time":"20070102","count":4},{"time":"20070103","count":8},{"time":"20070104","count":4},{"time":"20070105","count":12},{"time":"20070108","count":5},{"time":"20070109","count":3},{"time":"20070110","count":9},{"time":"20070111","count":5},{"time":"20070112","count":3},{"time":"20070115","count":1},{"time":"20070116","count":11},{"time":"20070117","count":5},{"time":"20070118","count":2},{"time":"20070119","count":6},{"time":"20070122","count":7},{"time":"20070123","count":8},{"time":"20070124","count":9},{"time":"20070125","count":3},{"time":"20070126","count":5},{"time":"20070129","count":7},{"time":"20070130","count":9},{"time":"20070131","count":6},{"time":"20070201","count":7},{"time":"20070202","count":3},{"time":"20070205","count":4},{"time":"20070206","count":9},{"time":"20070207","count":1},{"time":"20070208","count":3},{"time":"20070209","count":6},{"time":"20070212","count":2},{"time":"20070213","count":1},{"time":"20070214","count":3},{"time":"20070216","count":7},{"time":"20070219","count":2},{"time":"20070220","count":7},{"time":"20070222","count":2},{"time":"20070223","count":10},{"time":"20070226","count":2},{"time":"20070227","count":10},{"time":"20070228","count":9},{"time":"20070301","count":2},{"time":"20070302","count":3},{"time":"20070305","count":3},{"time":"20070306","count":2},{"time":"20070307","count":1},{"time":"20070308","count":5},{"time":"20070309","count":8},{"time":"20070312","count":4},{"time":"20070313","count":6},{"time":"20070314","count":6},{"time":"20070315","count":4},{"time":"20070316","count":4},{"time":"20070319","count":3},{"time":"20070320","count":5},{"time":"20070321","count":5},{"time":"20070322","count":5},{"time":"20070323","count":3},{"time":"20070326","count":7},{"time":"20070327","count":4},{"time":"20070328","count":3},{"time":"20070329","count":5},{"time":"20070330","count":5},{"time":"20070402","count":6},{"time":"20070403","count":4},{"time":"20070404","count":10},{"time":"20070405","count":9},{"time":"20070406","count":8},{"time":"20070409","count":5},{"time":"20070410","count":5},{"time":"20070411","count":6},{"time":"20070412","count":3},{"time":"20070413","count":7},{"time":"20070416","count":11},{"time":"20070417","count":7},{"time":"20070418","count":1},{"time":"20070419","count":3},{"time":"20070420","count":6},{"time":"20070423","count":8},{"time":"20070424","count":6},{"time":"20070425","count":7},{"time":"20070426","count":5},{"time":"20070427","count":3},{"time":"20070428","count":1},{"time":"20070430","count":4},{"time":"20070501","count":12},{"time":"20070503","count":2},{"time":"20070504","count":6},{"time":"20070507","count":7},{"time":"20070508","count":8},{"time":"20070509","count":5},{"time":"20070510","count":4},{"time":"20070511","count":6},{"time":"20070514","count":2},{"time":"20070515","count":2},{"time":"20070516","count":4},{"time":"20070517","count":4},{"time":"20070518","count":2},{"time":"20070521","count":6},{"time":"20070522","count":5},{"time":"20070523","count":6},{"time":"20070524","count":2},{"time":"20070525","count":3},{"time":"20070529","count":5},{"time":"20070530","count":2},{"time":"20070531","count":4},{"time":"20070601","count":3},{"time":"20070604","count":5},{"time":"20070606","count":3},{"time":"20070607","count":4},{"time":"20070608","count":5},{"time":"20070611","count":5},{"time":"20070612","count":1},{"time":"20070613","count":2},{"time":"20070614","count":3},{"time":"20070615","count":7},{"time":"20070618","count":1},{"time":"20070619","count":3},{"time":"20070620","count":9},{"time":"20070621","count":5},{"time":"20070622","count":4},{"time":"20070625","count":3},{"time":"20070626","count":8},{"time":"20070627","count":3},{"time":"20070628","count":2},{"time":"20070629","count":6},{"time":"20070702","count":8},{"time":"20070703","count":5},{"time":"20070705","count":9},{"time":"20070706","count":6},{"time":"20070709","count":3},{"time":"20070710","count":8},{"time":"20070711","count":6},{"time":"20070712","count":9},{"time":"20070713","count":10},{"time":"20070716","count":5},{"time":"20070717","count":4},{"time":"20070718","count":1},{"time":"20070719","count":4},{"time":"20070720","count":1},{"time":"20070723","count":5},{"time":"20070724","count":5},{"time":"20070725","count":5},{"time":"20070726","count":3},{"time":"20070727","count":4},{"time":"20070730","count":9},{"time":"20070731","count":5},{"time":"20070801","count":2},{"time":"20070802","count":4},{"time":"20070803","count":4},{"time":"20070806","count":10},{"time":"20070807","count":5},{"time":"20070808","count":4},{"time":"20070809","count":4},{"time":"20070810","count":9},{"time":"20070813","count":6},{"time":"20070814","count":5},{"time":"20070815","count":3},{"time":"20070816","count":3},{"time":"20070817","count":2},{"time":"20070820","count":9},{"time":"20070821","count":3},{"time":"20070822","count":7},{"time":"20070823","count":4},{"time":"20070824","count":5},{"time":"20070827","count":3},{"time":"20070828","count":2},{"time":"20070829","count":5},{"time":"20070830","count":4},{"time":"20070831","count":3},{"time":"20070904","count":8},{"time":"20070905","count":2},{"time":"20070906","count":2},{"time":"20070907","count":5},{"time":"20070910","count":5},{"time":"20070911","count":4},{"time":"20070912","count":9},{"time":"20070913","count":8},{"time":"20070914","count":4},{"time":"20070917","count":9},{"time":"20070918","count":4},{"time":"20070919","count":8},{"time":"20070920","count":8},{"time":"20070921","count":11},{"time":"20070924","count":6},{"time":"20070925","count":6},{"time":"20070926","count":6},{"time":"20070927","count":6},{"time":"20070928","count":7},{"time":"20071001","count":48},{"time":"20071002","count":6},{"time":"20071003","count":8},{"time":"20071004","count":1},{"time":"20071005","count":4},{"time":"20071008","count":3},{"time":"20071009","count":4},{"time":"20071010","count":3},{"time":"20071011","count":3},{"time":"20071012","count":3},{"time":"20071015","count":1},{"time":"20071016","count":3},{"time":"20071017","count":4},{"time":"20071018","count":5},{"time":"20071019","count":4},{"time":"20071022","count":4},{"time":"20071023","count":6},{"time":"20071024","count":4},{"time":"20071025","count":13},{"time":"20071026","count":8},{"time":"20071029","count":9},{"time":"20071030","count":5},{"time":"20071031","count":7},{"time":"20071101","count":9},{"time":"20071102","count":5},{"time":"20071105","count":5},{"time":"20071106","count":3},{"time":"20071107","count":6},{"time":"20071108","count":5},{"time":"20071109","count":6},{"time":"20071112","count":3},{"time":"20071113","count":4},{"time":"20071114","count":2},{"time":"20071115","count":3},{"time":"20071116","count":3},{"time":"20071119","count":2},{"time":"20071120","count":5},{"time":"20071121","count":4},{"time":"20071123","count":7},{"time":"20071126","count":4},{"time":"20071127","count":7},{"time":"20071128","count":2},{"time":"20071129","count":3},{"time":"20071130","count":6},{"time":"20071203","count":5},{"time":"20071204","count":3},{"time":"20071205","count":1},{"time":"20071206","count":3},{"time":"20071207","count":7},{"time":"20071210","count":6},{"time":"20071211","count":2},{"time":"20071212","count":5},{"time":"20071213","count":6},{"time":"20071214","count":9},{"time":"20071215","count":3},{"time":"20071217","count":2},{"time":"20071218","count":6},{"time":"20071219","count":2},{"time":"20071220","count":4},{"time":"20071221","count":4},{"time":"20071224","count":1},{"time":"20071226","count":3},{"time":"20071227","count":3},{"time":"20071228","count":7},{"time":"20071231","count":3},{"time":"20080102","count":12},{"time":"20080103","count":4},{"time":"20080104","count":6},{"time":"20080107","count":5},{"time":"20080108","count":6},{"time":"20080109","count":5},{"time":"20080110","count":4},{"time":"20080111","count":5},{"time":"20080114","count":4},{"time":"20080115","count":2},{"time":"20080116","count":6},{"time":"20080117","count":2},{"time":"20080118","count":4},{"time":"20080121","count":2},{"time":"20080122","count":8},{"time":"20080123","count":5},{"time":"20080124","count":4},{"time":"20080125","count":7},{"time":"20080128","count":11},{"time":"20080129","count":4},{"time":"20080130","count":9},{"time":"20080131","count":19},{"time":"20080201","count":5},{"time":"20080204","count":3},{"time":"20080205","count":6},{"time":"20080206","count":6},{"time":"20080207","count":4},{"time":"20080208","count":8},{"time":"20080211","count":9},{"time":"20080212","count":4},{"time":"20080213","count":6},{"time":"20080214","count":9},{"time":"20080215","count":9},{"time":"20080218","count":1},{"time":"20080219","count":4},{"time":"20080220","count":2},{"time":"20080221","count":9},{"time":"20080222","count":5},{"time":"20080224","count":1},{"time":"20080225","count":11},{"time":"20080226","count":4},{"time":"20080227","count":14},{"time":"20080228","count":8},{"time":"20080229","count":11},{"time":"20080303","count":3},{"time":"20080304","count":8},{"time":"20080305","count":5},{"time":"20080306","count":2},{"time":"20080307","count":6},{"time":"20080310","count":5},{"time":"20080311","count":6},{"time":"20080312","count":6},{"time":"20080313","count":7},{"time":"20080314","count":5},{"time":"20080315","count":9},{"time":"20080317","count":7},{"time":"20080318","count":3},{"time":"20080319","count":2},{"time":"20080320","count":3},{"time":"20080321","count":3},{"time":"20080324","count":8},{"time":"20080325","count":1},{"time":"20080326","count":4},{"time":"20080327","count":8},{"time":"20080328","count":15},{"time":"20080331","count":25},{"time":"20080401","count":10},{"time":"20080402","count":3},{"time":"20080403","count":5},{"time":"20080404","count":10},{"time":"20080407","count":6},{"time":"20080408","count":5},{"time":"20080409","count":1},{"time":"20080410","count":6},{"time":"20080411","count":6},{"time":"20080414","count":12},{"time":"20080415","count":6},{"time":"20080416","count":4},{"time":"20080417","count":6},{"time":"20080418","count":8},{"time":"20080421","count":7},{"time":"20080422","count":11},{"time":"20080423","count":10},{"time":"20080424","count":11},{"time":"20080425","count":7},{"time":"20080426","count":1},{"time":"20080428","count":5},{"time":"20080429","count":7},{"time":"20080430","count":7},{"time":"20080501","count":7},{"time":"20080502","count":4},{"time":"20080505","count":10},{"time":"20080506","count":2},{"time":"20080507","count":3},{"time":"20080508","count":4},{"time":"20080509","count":4},{"time":"20080512","count":3},{"time":"20080513","count":1},{"time":"20080514","count":2},{"time":"20080515","count":6},{"time":"20080516","count":5},{"time":"20080519","count":3},{"time":"20080520","count":3},{"time":"20080521","count":3},{"time":"20080522","count":3},{"time":"20080523","count":2},{"time":"20080526","count":3},{"time":"20080527","count":9},{"time":"20080528","count":1},{"time":"20080529","count":5},{"time":"20080530","count":5},{"time":"20080601","count":1},{"time":"20080602","count":5},{"time":"20080603","count":4},{"time":"20080604","count":8},{"time":"20080605","count":6},{"time":"20080606","count":3},{"time":"20080609","count":2},{"time":"20080610","count":2},{"time":"20080611","count":4},{"time":"20080612","count":1},{"time":"20080613","count":2},{"time":"20080616","count":8},{"time":"20080617","count":5},{"time":"20080618","count":10},{"time":"20080619","count":9},{"time":"20080620","count":2},{"time":"20080623","count":2},{"time":"20080624","count":5},{"time":"20080625","count":1},{"time":"20080626","count":6},{"time":"20080627","count":4},{"time":"20080630","count":11},{"time":"20080701","count":9},{"time":"20080702","count":12},{"time":"20080703","count":6},{"time":"20080704","count":1},{"time":"20080705","count":1},{"time":"20080707","count":6},{"time":"20080708","count":10},{"time":"20080709","count":11},{"time":"20080710","count":19},{"time":"20080711","count":7},{"time":"20080714","count":13},{"time":"20080715","count":8},{"time":"20080716","count":8},{"time":"20080717","count":9},{"time":"20080718","count":9},{"time":"20080721","count":3},{"time":"20080722","count":8},{"time":"20080723","count":7},{"time":"20080724","count":8},{"time":"20080725","count":9},{"time":"20080728","count":8},{"time":"20080729","count":9},{"time":"20080730","count":5},{"time":"20080731","count":10},{"time":"20080801","count":10},{"time":"20080804","count":8},{"time":"20080805","count":12},{"time":"20080806","count":8},{"time":"20080807","count":8},{"time":"20080808","count":6},{"time":"20080811","count":15},{"time":"20080812","count":9},{"time":"20080813","count":2},{"time":"20080814","count":6},{"time":"20080815","count":8},{"time":"20080817","count":1},{"time":"20080818","count":8},{"time":"20080819","count":14},{"time":"20080820","count":5},{"time":"20080821","count":8},{"time":"20080822","count":5},{"time":"20080825","count":9},{"time":"20080826","count":8},{"time":"20080827","count":8},{"time":"20080828","count":8},{"time":"20080829","count":5},{"time":"20080902","count":6},{"time":"20080903","count":6},{"time":"20080904","count":13},{"time":"20080905","count":15},{"time":"20080908","count":7},{"time":"20080909","count":8},{"time":"20080910","count":6},{"time":"20080911","count":8},{"time":"20080912","count":21},{"time":"20080915","count":14},{"time":"20080916","count":3},{"time":"20080917","count":11},{"time":"20080918","count":2},{"time":"20080919","count":11},{"time":"20080922","count":15},{"time":"20080923","count":6},{"time":"20080924","count":61},{"time":"20080925","count":3},{"time":"20080926","count":7},{"time":"20080929","count":7},{"time":"20080930","count":8},{"time":"20081001","count":10},{"time":"20081002","count":8},{"time":"20081003","count":13},{"time":"20081006","count":9},{"time":"20081007","count":9},{"time":"20081008","count":3},{"time":"20081009","count":2},{"time":"20081010","count":7},{"time":"20081013","count":6},{"time":"20081014","count":8},{"time":"20081015","count":5},{"time":"20081016","count":10},{"time":"20081017","count":5},{"time":"20081018","count":1},{"time":"20081020","count":24},{"time":"20081021","count":17},{"time":"20081022","count":23},{"time":"20081023","count":13},{"time":"20081024","count":5},{"time":"20081027","count":2},{"time":"20081028","count":9},{"time":"20081029","count":5},{"time":"20081030","count":12},{"time":"20081031","count":14},{"time":"20081103","count":15},{"time":"20081104","count":8},{"time":"20081105","count":4},{"time":"20081106","count":9},{"time":"20081107","count":8},{"time":"20081110","count":7},{"time":"20081111","count":2},{"time":"20081112","count":5},{"time":"20081113","count":9},{"time":"20081114","count":3},{"time":"20081117","count":6},{"time":"20081118","count":8},{"time":"20081119","count":7},{"time":"20081120","count":5},{"time":"20081121","count":10},{"time":"20081122","count":3},{"time":"20081124","count":6},{"time":"20081125","count":5},{"time":"20081126","count":9},{"time":"20081128","count":3},{"time":"20081201","count":11},{"time":"20081202","count":8},{"time":"20081203","count":2},{"time":"20081204","count":3},{"time":"20081205","count":4},{"time":"20081208","count":3},{"time":"20081210","count":1},{"time":"20081211","count":3},{"time":"20081212","count":6},{"time":"20081215","count":8},{"time":"20081216","count":5},{"time":"20081217","count":5},{"time":"20081218","count":10},{"time":"20081219","count":9},{"time":"20081221","count":3},{"time":"20081222","count":4},{"time":"20081223","count":5},{"time":"20081224","count":4},{"time":"20081226","count":5},{"time":"20081229","count":8},{"time":"20081230","count":3},{"time":"20081231","count":8},{"time":"20090102","count":1},{"time":"20090105","count":7},{"time":"20090106","count":8},{"time":"20090107","count":8},{"time":"20090108","count":6},{"time":"20090109","count":9},{"time":"20090111","count":1},{"time":"20090112","count":7},{"time":"20090113","count":4},{"time":"20090114","count":4},{"time":"20090115","count":5},{"time":"20090116","count":6},{"time":"20090119","count":2},{"time":"20090120","count":7},{"time":"20090121","count":14},{"time":"20090122","count":6},{"time":"20090123","count":5},{"time":"20090126","count":9},{"time":"20090127","count":9},{"time":"20090128","count":1},{"time":"20090129","count":4},{"time":"20090130","count":9},{"time":"20090202","count":5},{"time":"20090203","count":3},{"time":"20090204","count":4},{"time":"20090205","count":3},{"time":"20090206","count":2},{"time":"20090209","count":3},{"time":"20090210","count":2},{"time":"20090211","count":5},{"time":"20090212","count":3},{"time":"20090213","count":8},{"time":"20090216","count":4},{"time":"20090217","count":3},{"time":"20090218","count":7},{"time":"20090219","count":11},{"time":"20090220","count":11},{"time":"20090223","count":7},{"time":"20090224","count":6},{"time":"20090225","count":9},{"time":"20090226","count":3},{"time":"20090227","count":6},{"time":"20090302","count":6},{"time":"20090303","count":7},{"time":"20090304","count":4},{"time":"20090305","count":11},{"time":"20090306","count":5},{"time":"20090309","count":4},{"time":"20090310","count":4},{"time":"20090311","count":8},{"time":"20090312","count":5},{"time":"20090313","count":4},{"time":"20090314","count":3},{"time":"20090316","count":1},{"time":"20090317","count":7},{"time":"20090318","count":5},{"time":"20090319","count":5},{"time":"20090320","count":7},{"time":"20090323","count":10},{"time":"20090324","count":9},{"time":"20090325","count":5},{"time":"20090326","count":5},{"time":"20090327","count":8},{"time":"20090330","count":4},{"time":"20090331","count":2},{"time":"20090401","count":7},{"time":"20090402","count":5},{"time":"20090403","count":8},{"time":"20090406","count":5},{"time":"20090407","count":7},{"time":"20090408","count":5},{"time":"20090409","count":4},{"time":"20090410","count":7},{"time":"20090413","count":8},{"time":"20090414","count":5},{"time":"20090415","count":9},{"time":"20090416","count":1},{"time":"20090417","count":7},{"time":"20090420","count":9},{"time":"20090421","count":1},{"time":"20090422","count":5},{"time":"20090423","count":5},{"time":"20090424","count":5},{"time":"20090427","count":8},{"time":"20090428","count":7},{"time":"20090429","count":6},{"time":"20090430","count":7},{"time":"20090501","count":9},{"time":"20090504","count":10},{"time":"20090505","count":7},{"time":"20090506","count":3},{"time":"20090507","count":10},{"time":"20090508","count":7},{"time":"20090511","count":5},{"time":"20090512","count":10},{"time":"20090513","count":8},{"time":"20090514","count":7},{"time":"20090515","count":14},{"time":"20090518","count":4},{"time":"20090519","count":8},{"time":"20090520","count":5},{"time":"20090521","count":8},{"time":"20090522","count":23},{"time":"20090526","count":10},{"time":"20090527","count":6},{"time":"20090528","count":11},{"time":"20090529","count":13},{"time":"20090601","count":4},{"time":"20090602","count":1},{"time":"20090603","count":5},{"time":"20090604","count":13},{"time":"20090605","count":6},{"time":"20090606","count":1},{"time":"20090608","count":5},{"time":"20090609","count":5},{"time":"20090610","count":11},{"time":"20090611","count":7},{"time":"20090612","count":16},{"time":"20090615","count":8},{"time":"20090616","count":5},{"time":"20090617","count":11},{"time":"20090618","count":4},{"time":"20090619","count":15},{"time":"20090621","count":1},{"time":"20090622","count":7},{"time":"20090623","count":44},{"time":"20090624","count":11},{"time":"20090625","count":10},{"time":"20090626","count":11},{"time":"20090629","count":7},{"time":"20090630","count":29},{"time":"20090701","count":10},{"time":"20090702","count":9},{"time":"20090706","count":19},{"time":"20090707","count":9},{"time":"20090708","count":3},{"time":"20090709","count":7},{"time":"20090710","count":8},{"time":"20090713","count":6},{"time":"20090714","count":9},{"time":"20090715","count":4},{"time":"20090716","count":11},{"time":"20090717","count":9},{"time":"20090720","count":12},{"time":"20090721","count":9},{"time":"20090722","count":11},{"time":"20090723","count":6},{"time":"20090724","count":8},{"time":"20090727","count":9},{"time":"20090728","count":4},{"time":"20090729","count":10},{"time":"20090730","count":11},{"time":"20090731","count":11},{"time":"20090803","count":11},{"time":"20090804","count":5},{"time":"20090805","count":9},{"time":"20090806","count":5},{"time":"20090807","count":5},{"time":"20090810","count":9},{"time":"20090811","count":5},{"time":"20090812","count":5},{"time":"20090813","count":11},{"time":"20090814","count":6},{"time":"20090817","count":10},{"time":"20090818","count":3},{"time":"20090819","count":10},{"time":"20090820","count":6},{"time":"20090821","count":9},{"time":"20090822","count":2},{"time":"20090824","count":9},{"time":"20090825","count":5},{"time":"20090826","count":10},{"time":"20090827","count":8},{"time":"20090828","count":7},{"time":"20090831","count":8},{"time":"20090901","count":1},{"time":"20090903","count":4},{"time":"20090904","count":5},{"time":"20090908","count":11},{"time":"20090909","count":3},{"time":"20090910","count":5},{"time":"20090911","count":4},{"time":"20090914","count":3},{"time":"20090916","count":4},{"time":"20090917","count":8},{"time":"20090918","count":8},{"time":"20090921","count":11},{"time":"20090922","count":6},{"time":"20090923","count":12},{"time":"20090924","count":6},{"time":"20090925","count":11},{"time":"20090928","count":7},{"time":"20090929","count":9},{"time":"20090930","count":18},{"time":"20091001","count":5},{"time":"20091002","count":9},{"time":"20091003","count":1},{"time":"20091005","count":7},{"time":"20091006","count":5},{"time":"20091007","count":4},{"time":"20091008","count":9},{"time":"20091009","count":98},{"time":"20091010","count":1},{"time":"20091012","count":3},{"time":"20091013","count":9},{"time":"20091014","count":7},{"time":"20091015","count":5},{"time":"20091016","count":7},{"time":"20091019","count":14},{"time":"20091020","count":13},{"time":"20091021","count":5},{"time":"20091022","count":7},{"time":"20091023","count":14},{"time":"20091024","count":1},{"time":"20091026","count":13},{"time":"20091027","count":8},{"time":"20091028","count":2},{"time":"20091029","count":8},{"time":"20091030","count":22},{"time":"20091102","count":10},{"time":"20091103","count":5},{"time":"20091104","count":10},{"time":"20091105","count":7},{"time":"20091106","count":6},{"time":"20091109","count":8},{"time":"20091110","count":2},{"time":"20091111","count":4},{"time":"20091112","count":8},{"time":"20091113","count":7},{"time":"20091116","count":9},{"time":"20091117","count":5},{"time":"20091118","count":5},{"time":"20091119","count":4},{"time":"20091120","count":5},{"time":"20091123","count":15},{"time":"20091124","count":4},{"time":"20091125","count":5},{"time":"20091127","count":6},{"time":"20091130","count":18},{"time":"20091201","count":11},{"time":"20091202","count":8},{"time":"20091203","count":11},{"time":"20091204","count":17},{"time":"20091207","count":7},{"time":"20091208","count":14},{"time":"20091209","count":8},{"time":"20091210","count":7},{"time":"20091211","count":8},{"time":"20091214","count":14},{"time":"20091215","count":6},{"time":"20091216","count":3},{"time":"20091217","count":4},{"time":"20091218","count":10},{"time":"20091221","count":10},{"time":"20091222","count":11},{"time":"20091223","count":5},{"time":"20091224","count":4},{"time":"20091225","count":1},{"time":"20091228","count":14},{"time":"20091229","count":7},{"time":"20091230","count":5},{"time":"20091231","count":3},{"time":"20100101","count":1},{"time":"20100104","count":11},{"time":"20100105","count":4},{"time":"20100106","count":5},{"time":"20100107","count":7},{"time":"20100108","count":10},{"time":"20100111","count":9},{"time":"20100112","count":5},{"time":"20100113","count":1},{"time":"20100114","count":4},{"time":"20100115","count":3},{"time":"20100118","count":5},{"time":"20100119","count":6},{"time":"20100120","count":6},{"time":"20100121","count":2},{"time":"20100122","count":8},{"time":"20100123","count":1},{"time":"20100125","count":16},{"time":"20100126","count":8},{"time":"20100127","count":6},{"time":"20100128","count":8},{"time":"20100129","count":12},{"time":"20100130","count":1},{"time":"20100201","count":8},{"time":"20100202","count":3},{"time":"20100203","count":7},{"time":"20100204","count":6},{"time":"20100205","count":3},{"time":"20100208","count":5},{"time":"20100209","count":3},{"time":"20100210","count":2},{"time":"20100211","count":2},{"time":"20100212","count":19},{"time":"20100213","count":3},{"time":"20100215","count":5},{"time":"20100216","count":11},{"time":"20100217","count":6},{"time":"20100218","count":6},{"time":"20100219","count":8},{"time":"20100222","count":12},{"time":"20100223","count":9},{"time":"20100224","count":4},{"time":"20100225","count":13},{"time":"20100226","count":6},{"time":"20100228","count":1},{"time":"20100301","count":7},{"time":"20100302","count":5},{"time":"20100303","count":4},{"time":"20100304","count":6},{"time":"20100305","count":9},{"time":"20100306","count":1},{"time":"20100307","count":7},{"time":"20100308","count":7},{"time":"20100309","count":11},{"time":"20100310","count":4},{"time":"20100311","count":5},{"time":"20100312","count":7},{"time":"20100315","count":5},{"time":"20100316","count":4},{"time":"20100317","count":12},{"time":"20100318","count":8},{"time":"20100319","count":7},{"time":"20100321","count":1},{"time":"20100322","count":2},{"time":"20100323","count":6},{"time":"20100324","count":10},{"time":"20100325","count":11},{"time":"20100326","count":6},{"time":"20100329","count":9},{"time":"20100330","count":7},{"time":"20100331","count":5},{"time":"20100401","count":7},{"time":"20100402","count":8},{"time":"20100405","count":4},{"time":"20100406","count":6},{"time":"20100407","count":4},{"time":"20100408","count":7},{"time":"20100409","count":7},{"time":"20100412","count":2},{"time":"20100413","count":6},{"time":"20100414","count":7},{"time":"20100415","count":9},{"time":"20100416","count":10},{"time":"20100419","count":3},{"time":"20100420","count":14},{"time":"20100421","count":10},{"time":"20100422","count":3},{"time":"20100423","count":10},{"time":"20100426","count":14},{"time":"20100427","count":6},{"time":"20100428","count":7},{"time":"20100429","count":7},{"time":"20100430","count":10},{"time":"20100503","count":16},{"time":"20100504","count":14},{"time":"20100505","count":7},{"time":"20100506","count":10},{"time":"20100507","count":25},{"time":"20100510","count":9},{"time":"20100511","count":5},{"time":"20100512","count":7},{"time":"20100513","count":5},{"time":"20100514","count":10},{"time":"20100517","count":8},{"time":"20100518","count":11},{"time":"20100519","count":3},{"time":"20100520","count":6},{"time":"20100521","count":9},{"time":"20100524","count":13},{"time":"20100525","count":4},{"time":"20100526","count":7},{"time":"20100527","count":11},{"time":"20100528","count":12},{"time":"20100601","count":11},{"time":"20100602","count":6},{"time":"20100603","count":8},{"time":"20100604","count":8},{"time":"20100607","count":6},{"time":"20100608","count":3},{"time":"20100609","count":7},{"time":"20100610","count":2},{"time":"20100611","count":8},{"time":"20100614","count":9},{"time":"20100615","count":4},{"time":"20100616","count":8},{"time":"20100617","count":2},{"time":"20100618","count":3},{"time":"20100621","count":10},{"time":"20100622","count":5},{"time":"20100623","count":11},{"time":"20100624","count":14},{"time":"20100625","count":4},{"time":"20100628","count":8},{"time":"20100629","count":12},{"time":"20100630","count":11},{"time":"20100701","count":12},{"time":"20100702","count":6},{"time":"20100704","count":1},{"time":"20100705","count":2},{"time":"20100706","count":16},{"time":"20100707","count":7},{"time":"20100708","count":9},{"time":"20100709","count":22},{"time":"20100712","count":19},{"time":"20100713","count":15},{"time":"20100714","count":15},{"time":"20100715","count":7},{"time":"20100716","count":11},{"time":"20100717","count":2},{"time":"20100719","count":12},{"time":"20100720","count":6},{"time":"20100721","count":14},{"time":"20100722","count":9},{"time":"20100723","count":5},{"time":"20100727","count":7},{"time":"20100728","count":7},{"time":"20100729","count":10},{"time":"20100730","count":24},{"time":"20100731","count":5},{"time":"20100802","count":7},{"time":"20100803","count":14},{"time":"20100804","count":14},{"time":"20100805","count":4},{"time":"20100806","count":13},{"time":"20100809","count":7},{"time":"20100810","count":12},{"time":"20100811","count":7},{"time":"20100812","count":12},{"time":"20100813","count":10},{"time":"20100816","count":10},{"time":"20100817","count":22},{"time":"20100818","count":15},{"time":"20100819","count":9},{"time":"20100820","count":17},{"time":"20100821","count":2},{"time":"20100822","count":1},{"time":"20100823","count":17},{"time":"20100824","count":10},{"time":"20100825","count":9},{"time":"20100826","count":8},{"time":"20100827","count":8},{"time":"20100829","count":10},{"time":"20100830","count":6},{"time":"20100831","count":6},{"time":"20100901","count":13},{"time":"20100902","count":9},{"time":"20100903","count":8},{"time":"20100907","count":10},{"time":"20100908","count":11},{"time":"20100909","count":5},{"time":"20100910","count":12},{"time":"20100913","count":8},{"time":"20100914","count":10},{"time":"20100915","count":2},{"time":"20100916","count":11},{"time":"20100917","count":6},{"time":"20100920","count":17},{"time":"20100921","count":8},{"time":"20100922","count":19},{"time":"20100923","count":8},{"time":"20100924","count":11},{"time":"20100927","count":10},{"time":"20100928","count":6},{"time":"20100929","count":6},{"time":"20100930","count":7},{"time":"20101001","count":3},{"time":"20101003","count":1},{"time":"20101004","count":11},{"time":"20101005","count":8},{"time":"20101006","count":5},{"time":"20101007","count":10},{"time":"20101008","count":11},{"time":"20101011","count":14},{"time":"20101012","count":14},{"time":"20101013","count":13},{"time":"20101014","count":3},{"time":"20101015","count":8},{"time":"20101018","count":9},{"time":"20101019","count":11},{"time":"20101020","count":6},{"time":"20101021","count":6},{"time":"20101022","count":7},{"time":"20101025","count":9},{"time":"20101026","count":10},{"time":"20101027","count":16},{"time":"20101028","count":15},{"time":"20101029","count":16},{"time":"20101101","count":7},{"time":"20101102","count":14},{"time":"20101103","count":15},{"time":"20101104","count":12},{"time":"20101105","count":5},{"time":"20101108","count":3},{"time":"20101109","count":19},{"time":"20101110","count":13},{"time":"20101111","count":9},{"time":"20101112","count":7},{"time":"20101115","count":15},{"time":"20101116","count":6},{"time":"20101117","count":5},{"time":"20101118","count":14},{"time":"20101119","count":6},{"time":"20101122","count":9},{"time":"20101123","count":21},{"time":"20101124","count":8},{"time":"20101125","count":3},{"time":"20101126","count":3},{"time":"20101129","count":14},{"time":"20101130","count":12},{"time":"20101201","count":5},{"time":"20101202","count":3},{"time":"20101203","count":5},{"time":"20101206","count":7},{"time":"20101207","count":9},{"time":"20101208","count":9},{"time":"20101209","count":5},{"time":"20101210","count":4},{"time":"20101212","count":1},{"time":"20101213","count":18},{"time":"20101214","count":11},{"time":"20101215","count":8},{"time":"20101216","count":4},{"time":"20101217","count":12},{"time":"20101220","count":16},{"time":"20101221","count":13},{"time":"20101222","count":4},{"time":"20101223","count":16},{"time":"20101224","count":1},{"time":"20101226","count":1},{"time":"20101227","count":7},{"time":"20101228","count":5},{"time":"20101229","count":15},{"time":"20101230","count":4},{"time":"20110103","count":4},{"time":"20110104","count":6},{"time":"20110105","count":15},{"time":"20110106","count":11},{"time":"20110107","count":12},{"time":"20110110","count":4},{"time":"20110111","count":5},{"time":"20110112","count":8},{"time":"20110113","count":6},{"time":"20110114","count":4},{"time":"20110117","count":5},{"time":"20110118","count":8},{"time":"20110119","count":17},{"time":"20110120","count":9},{"time":"20110121","count":6},{"time":"20110122","count":1},{"time":"20110124","count":10},{"time":"20110125","count":8},{"time":"20110126","count":9},{"time":"20110127","count":5},{"time":"20110128","count":17},{"time":"20110129","count":62},{"time":"20110130","count":18},{"time":"20110131","count":12},{"time":"20110201","count":18},{"time":"20110202","count":8},{"time":"20110203","count":11},{"time":"20110204","count":5},{"time":"20110207","count":8},{"time":"20110208","count":8},{"time":"20110209","count":14},{"time":"20110210","count":9},{"time":"20110211","count":8},{"time":"20110214","count":13},{"time":"20110215","count":8},{"time":"20110216","count":9},{"time":"20110217","count":5},{"time":"20110218","count":9},{"time":"20110221","count":3},{"time":"20110222","count":7},{"time":"20110223","count":11},{"time":"20110224","count":13},{"time":"20110225","count":16},{"time":"20110226","count":1},{"time":"20110228","count":14},{"time":"20110301","count":12},{"time":"20110302","count":27},{"time":"20110303","count":12},{"time":"20110304","count":9},{"time":"20110305","count":2},{"time":"20110307","count":39},{"time":"20110308","count":9},{"time":"20110309","count":15},{"time":"20110310","count":13},{"time":"20110311","count":10},{"time":"20110314","count":11},{"time":"20110315","count":10},{"time":"20110316","count":9},{"time":"20110317","count":8},{"time":"20110318","count":8},{"time":"20110320","count":1},{"time":"20110321","count":15},{"time":"20110322","count":21},{"time":"20110323","count":9},{"time":"20110324","count":11},{"time":"20110325","count":13},{"time":"20110328","count":6},{"time":"20110329","count":12},{"time":"20110330","count":5},{"time":"20110331","count":7},{"time":"20110401","count":11},{"time":"20110404","count":17},{"time":"20110405","count":18},{"time":"20110406","count":16},{"time":"20110407","count":6},{"time":"20110408","count":18},{"time":"20110411","count":14},{"time":"20110412","count":11},{"time":"20110413","count":13},{"time":"20110414","count":2},{"time":"20110415","count":14},{"time":"20110418","count":18},{"time":"20110419","count":17},{"time":"20110420","count":14},{"time":"20110421","count":5},{"time":"20110422","count":6},{"time":"20110425","count":9},{"time":"20110426","count":18},{"time":"20110427","count":12},{"time":"20110428","count":15},{"time":"20110429","count":22},{"time":"20110502","count":14},{"time":"20110503","count":16},{"time":"20110504","count":7},{"time":"20110505","count":14},{"time":"20110506","count":17},{"time":"20110509","count":19},{"time":"20110510","count":16},{"time":"20110511","count":10},{"time":"20110512","count":13},{"time":"20110513","count":18},{"time":"20110516","count":11},{"time":"20110517","count":24},{"time":"20110518","count":19},{"time":"20110519","count":12},{"time":"20110520","count":14},{"time":"20110523","count":7},{"time":"20110524","count":20},{"time":"20110525","count":16},{"time":"20110526","count":9},{"time":"20110527","count":14},{"time":"20110529","count":1},{"time":"20110530","count":2},{"time":"20110531","count":13},{"time":"20110601","count":18},{"time":"20110602","count":10},{"time":"20110603","count":23},{"time":"20110606","count":2},{"time":"20110607","count":12},{"time":"20110608","count":6},{"time":"20110609","count":13},{"time":"20110610","count":5},{"time":"20110613","count":12},{"time":"20110614","count":13},{"time":"20110615","count":6},{"time":"20110616","count":9},{"time":"20110617","count":10},{"time":"20110618","count":2},{"time":"20110620","count":5},{"time":"20110621","count":6},{"time":"20110622","count":12},{"time":"20110623","count":5},{"time":"20110624","count":5},{"time":"20110627","count":18},{"time":"20110628","count":12},{"time":"20110629","count":12},{"time":"20110630","count":5},{"time":"20110701","count":18},{"time":"20110702","count":1},{"time":"20110705","count":24},{"time":"20110706","count":7},{"time":"20110707","count":14},{"time":"20110708","count":4},{"time":"20110711","count":12},{"time":"20110712","count":6},{"time":"20110713","count":18},{"time":"20110714","count":8},{"time":"20110715","count":7},{"time":"20110718","count":10},{"time":"20110719","count":7},{"time":"20110720","count":15},{"time":"20110721","count":8},{"time":"20110722","count":17},{"time":"20110725","count":8},{"time":"20110726","count":11},{"time":"20110727","count":7},{"time":"20110728","count":14},{"time":"20110729","count":12},{"time":"20110801","count":6},{"time":"20110802","count":12},{"time":"20110803","count":6},{"time":"20110804","count":8},{"time":"20110805","count":6},{"time":"20110808","count":10},{"time":"20110809","count":8},{"time":"20110810","count":13},{"time":"20110811","count":19},{"time":"20110812","count":29},{"time":"20110815","count":7},{"time":"20110816","count":14},{"time":"20110817","count":7},{"time":"20110818","count":23},{"time":"20110819","count":17},{"time":"20110822","count":16},{"time":"20110823","count":21},{"time":"20110824","count":9},{"time":"20110825","count":9},{"time":"20110826","count":18},{"time":"20110829","count":13},{"time":"20110830","count":12},{"time":"20110831","count":17},{"time":"20110901","count":49},{"time":"20110902","count":15},{"time":"20110905","count":3},{"time":"20110906","count":17},{"time":"20110907","count":17},{"time":"20110908","count":14},{"time":"20110909","count":9},{"time":"20110911","count":1},{"time":"20110912","count":13},{"time":"20110913","count":10},{"time":"20110914","count":7},{"time":"20110915","count":9},{"time":"20110916","count":11},{"time":"20110917","count":1},{"time":"20110919","count":8},{"time":"20110920","count":19},{"time":"20110921","count":7},{"time":"20110922","count":17},{"time":"20110923","count":9},{"time":"20110926","count":28},{"time":"20110927","count":14},{"time":"20110928","count":9},{"time":"20110929","count":13},{"time":"20110930","count":19},{"time":"20111002","count":1},{"time":"20111003","count":31},{"time":"20111004","count":23},{"time":"20111005","count":16},{"time":"20111006","count":28},{"time":"20111007","count":15},{"time":"20111010","count":8},{"time":"20111011","count":11},{"time":"20111012","count":17},{"time":"20111013","count":9},{"time":"20111014","count":13},{"time":"20111017","count":10},{"time":"20111018","count":12},{"time":"20111019","count":29},{"time":"20111020","count":56},{"time":"20111021","count":7},{"time":"20111022","count":45},{"time":"20111024","count":52},{"time":"20111025","count":15},{"time":"20111026","count":12},{"time":"20111027","count":13},{"time":"20111028","count":20},{"time":"20111031","count":11},{"time":"20111101","count":20},{"time":"20111102","count":10},{"time":"20111103","count":17},{"time":"20111104","count":11},{"time":"20111106","count":1},{"time":"20111107","count":12},{"time":"20111108","count":16},{"time":"20111109","count":13},{"time":"20111110","count":5},{"time":"20111111","count":6},{"time":"20111114","count":17},{"time":"20111115","count":7},{"time":"20111116","count":12},{"time":"20111117","count":14},{"time":"20111118","count":14},{"time":"20111121","count":12},{"time":"20111122","count":13},{"time":"20111123","count":14},{"time":"20111124","count":1},{"time":"20111125","count":2},{"time":"20111128","count":7},{"time":"20111129","count":12},{"time":"20111130","count":8},{"time":"20111201","count":15},{"time":"20111202","count":13},{"time":"20111205","count":6},{"time":"20111206","count":9},{"time":"20111207","count":5},{"time":"20111208","count":27},{"time":"20111209","count":8},{"time":"20111212","count":13},{"time":"20111213","count":10},{"time":"20111214","count":10},{"time":"20111215","count":7},{"time":"20111216","count":9},{"time":"20111217","count":2},{"time":"20111218","count":1},{"time":"20111219","count":18},{"time":"20111220","count":12},{"time":"20111221","count":15},{"time":"20111222","count":16},{"time":"20111223","count":8},{"time":"20111226","count":2},{"time":"20111227","count":27},{"time":"20111228","count":16},{"time":"20111229","count":10},{"time":"20111230","count":3},{"time":"20120103","count":24},{"time":"20120104","count":6},{"time":"20120105","count":13},{"time":"20120106","count":11},{"time":"20120109","count":22},{"time":"20120110","count":8},{"time":"20120111","count":13},{"time":"20120112","count":10},{"time":"20120113","count":12},{"time":"20120116","count":6},{"time":"20120117","count":18},{"time":"20120118","count":12},{"time":"20120119","count":14},{"time":"20120120","count":12},{"time":"20120123","count":21},{"time":"20120124","count":18},{"time":"20120125","count":12},{"time":"20120126","count":7},{"time":"20120127","count":28},{"time":"20120128","count":32},{"time":"20120129","count":34},{"time":"20120130","count":15},{"time":"20120131","count":18},{"time":"20120201","count":13},{"time":"20120202","count":21},{"time":"20120203","count":10},{"time":"20120206","count":16},{"time":"20120207","count":20},{"time":"20120208","count":22},{"time":"20120209","count":17},{"time":"20120210","count":8},{"time":"20120213","count":15},{"time":"20120214","count":11},{"time":"20120215","count":11},{"time":"20120216","count":6},{"time":"20120217","count":11},{"time":"20120218","count":1},{"time":"20120220","count":8},{"time":"20120221","count":11},{"time":"20120222","count":9},{"time":"20120223","count":11},{"time":"20120224","count":11},{"time":"20120227","count":23},{"time":"20120228","count":13},{"time":"20120229","count":21},{"time":"20120301","count":14},{"time":"20120302","count":20},{"time":"20120305","count":13},{"time":"20120306","count":7},{"time":"20120307","count":14},{"time":"20120308","count":7},{"time":"20120309","count":12},{"time":"20120311","count":2},{"time":"20120312","count":22},{"time":"20120313","count":14},{"time":"20120314","count":22},{"time":"20120315","count":14},{"time":"20120316","count":15},{"time":"20120319","count":15},{"time":"20120320","count":12},{"time":"20120321","count":18},{"time":"20120322","count":16},{"time":"20120323","count":56},{"time":"20120326","count":12},{"time":"20120327","count":12},{"time":"20120328","count":15},{"time":"20120329","count":12},{"time":"20120330","count":9},{"time":"20120401","count":1},{"time":"20120402","count":16},{"time":"20120403","count":16},{"time":"20120404","count":11},{"time":"20120405","count":16},{"time":"20120406","count":12},{"time":"20120409","count":8},{"time":"20120410","count":14},{"time":"20120411","count":15},{"time":"20120412","count":13},{"time":"20120413","count":21},{"time":"20120415","count":1},{"time":"20120416","count":9},{"time":"20120417","count":9},{"time":"20120418","count":11},{"time":"20120419","count":11},{"time":"20120420","count":13},{"time":"20120421","count":2},{"time":"20120423","count":11},{"time":"20120424","count":12},{"time":"20120425","count":10},{"time":"20120426","count":12},{"time":"20120427","count":7},{"time":"20120430","count":12},{"time":"20120501","count":8},{"time":"20120502","count":8},{"time":"20120503","count":10},{"time":"20120504","count":5},{"time":"20120507","count":16},{"time":"20120508","count":11},{"time":"20120509","count":4},{"time":"20120510","count":11},{"time":"20120511","count":13},{"time":"20120514","count":12},{"time":"20120515","count":12},{"time":"20120516","count":16},{"time":"20120517","count":11},{"time":"20120518","count":12},{"time":"20120521","count":15},{"time":"20120522","count":20},{"time":"20120523","count":20},{"time":"20120524","count":11},{"time":"20120525","count":16},{"time":"20120528","count":2},{"time":"20120529","count":16},{"time":"20120530","count":10},{"time":"20120531","count":13},{"time":"20120601","count":13},{"time":"20120602","count":1},{"time":"20120603","count":1},{"time":"20120604","count":10},{"time":"20120605","count":11},{"time":"20120606","count":14},{"time":"20120607","count":18},{"time":"20120608","count":14},{"time":"20120611","count":21},{"time":"20120612","count":17},{"time":"20120613","count":15},{"time":"20120614","count":17},{"time":"20120615","count":9},{"time":"20120618","count":13},{"time":"20120619","count":6},{"time":"20120620","count":7},{"time":"20120621","count":11},{"time":"20120622","count":13},{"time":"20120625","count":10},{"time":"20120626","count":11},{"time":"20120627","count":11},{"time":"20120628","count":5},{"time":"20120629","count":9},{"time":"20120702","count":10},{"time":"20120703","count":10},{"time":"20120704","count":2},{"time":"20120705","count":15},{"time":"20120706","count":9},{"time":"20120709","count":14},{"time":"20120710","count":10},{"time":"20120711","count":11},{"time":"20120712","count":8},{"time":"20120713","count":8},{"time":"20120716","count":14},{"time":"20120717","count":9},{"time":"20120718","count":20},{"time":"20120719","count":10},{"time":"20120720","count":16},{"time":"20120722","count":1},{"time":"20120723","count":5},{"time":"20120724","count":12},{"time":"20120725","count":8},{"time":"20120726","count":17},{"time":"20120727","count":11},{"time":"20120730","count":7},{"time":"20120731","count":7},{"time":"20120801","count":14},{"time":"20120802","count":11},{"time":"20120803","count":13},{"time":"20120805","count":1},{"time":"20120806","count":15},{"time":"20120807","count":19},{"time":"20120808","count":11},{"time":"20120809","count":8},{"time":"20120810","count":14},{"time":"20120813","count":13},{"time":"20120814","count":5},{"time":"20120815","count":7},{"time":"20120816","count":20},{"time":"20120817","count":8},{"time":"20120820","count":8},{"time":"20120821","count":19},{"time":"20120822","count":9},{"time":"20120823","count":11},{"time":"20120824","count":10},{"time":"20120827","count":10},{"time":"20120828","count":6},{"time":"20120829","count":15},{"time":"20120830","count":12},{"time":"20120831","count":13},{"time":"20120902","count":2},{"time":"20120903","count":1},{"time":"20120904","count":10},{"time":"20120905","count":7},{"time":"20120906","count":16},{"time":"20120907","count":12},{"time":"20120910","count":7},{"time":"20120911","count":11},{"time":"20120912","count":8},{"time":"20120913","count":16},{"time":"20120914","count":17},{"time":"20120917","count":13},{"time":"20120918","count":16},{"time":"20120919","count":17},{"time":"20120920","count":12},{"time":"20120921","count":19},{"time":"20120923","count":2},{"time":"20120924","count":23},{"time":"20120925","count":13},{"time":"20120926","count":15},{"time":"20120927","count":11},{"time":"20120928","count":17},{"time":"20121001","count":15},{"time":"20121002","count":8},{"time":"20121003","count":15},{"time":"20121004","count":17},{"time":"20121005","count":13},{"time":"20121007","count":1},{"time":"20121008","count":6},{"time":"20121009","count":9},{"time":"20121010","count":12},{"time":"20121011","count":10},{"time":"20121012","count":10},{"time":"20121015","count":11},{"time":"20121016","count":8},{"time":"20121017","count":12},{"time":"20121018","count":7},{"time":"20121019","count":6},{"time":"20121022","count":13},{"time":"20121023","count":12},{"time":"20121024","count":5},{"time":"20121025","count":9},{"time":"20121026","count":13},{"time":"20121028","count":1},{"time":"20121029","count":4},{"time":"20121030","count":5},{"time":"20121031","count":2},{"time":"20121101","count":10},{"time":"20121102","count":14},{"time":"20121104","count":1},{"time":"20121105","count":5},{"time":"20121106","count":10},{"time":"20121107","count":12},{"time":"20121108","count":10},{"time":"20121109","count":22},{"time":"20121112","count":12},{"time":"20121113","count":8},{"time":"20121114","count":14},{"time":"20121115","count":8},{"time":"20121116","count":3},{"time":"20121119","count":4},{"time":"20121120","count":5},{"time":"20121121","count":14},{"time":"20121122","count":3},{"time":"20121123","count":2},{"time":"20121126","count":17},{"time":"20121127","count":10},{"time":"20121128","count":7},{"time":"20121129","count":6},{"time":"20121130","count":14},{"time":"20121203","count":10},{"time":"20121204","count":11},{"time":"20121205","count":13},{"time":"20121206","count":19},{"time":"20121207","count":8},{"time":"20121210","count":11},{"time":"20121211","count":11},{"time":"20121212","count":16},{"time":"20121213","count":19},{"time":"20121214","count":13},{"time":"20121217","count":13},{"time":"20121218","count":11},{"time":"20121219","count":8},{"time":"20121220","count":14},{"time":"20121221","count":18},{"time":"20121222","count":1},{"time":"20121223","count":1},{"time":"20121224","count":10},{"time":"20121225","count":2},{"time":"20121226","count":20},{"time":"20121227","count":6},{"time":"20121228","count":18},{"time":"20121230","count":1},{"time":"20121231","count":4},{"time":"20130102","count":11},{"time":"20130103","count":13},{"time":"20130104","count":6},{"time":"20130107","count":15},{"time":"20130108","count":10},{"time":"20130109","count":10},{"time":"20130110","count":13},{"time":"20130111","count":21},{"time":"20130113","count":1},{"time":"20130114","count":13},{"time":"20130115","count":9},{"time":"20130116","count":8},{"time":"20130117","count":8},{"time":"20130118","count":7},{"time":"20130121","count":7},{"time":"20130122","count":12},{"time":"20130123","count":14},{"time":"20130124","count":7},{"time":"20130125","count":10},{"time":"20130128","count":15},{"time":"20130129","count":42},{"time":"20130130","count":28},{"time":"20130131","count":32},{"time":"20130201","count":12},{"time":"20130203","count":2},{"time":"20130204","count":11},{"time":"20130205","count":15},{"time":"20130206","count":10},{"time":"20130207","count":9},{"time":"20130208","count":9},{"time":"20130211","count":14},{"time":"20130212","count":13},{"time":"20130213","count":8},{"time":"20130214","count":13},{"time":"20130215","count":9},{"time":"20130218","count":7},{"time":"20130219","count":8},{"time":"20130220","count":11},{"time":"20130221","count":15},{"time":"20130222","count":14},{"time":"20130225","count":8},{"time":"20130226","count":6},{"time":"20130227","count":12},{"time":"20130228","count":10},{"time":"20130301","count":4},{"time":"20130304","count":18},{"time":"20130305","count":15},{"time":"20130306","count":8},{"time":"20130307","count":5},{"time":"20130308","count":9},{"time":"20130311","count":12},{"time":"20130312","count":11},{"time":"20130313","count":9},{"time":"20130314","count":13},{"time":"20130315","count":13},{"time":"20130316","count":1},{"time":"20130317","count":1},{"time":"20130318","count":13},{"time":"20130319","count":12},{"time":"20130320","count":13},{"time":"20130321","count":6},{"time":"20130322","count":12},{"time":"20130325","count":20},{"time":"20130326","count":19},{"time":"20130327","count":11},{"time":"20130328","count":15},{"time":"20130329","count":12},{"time":"20130331","count":1},{"time":"20130401","count":13},{"time":"20130402","count":12},{"time":"20130403","count":16},{"time":"20130404","count":7},{"time":"20130405","count":17},{"time":"20130408","count":12},{"time":"20130409","count":17},{"time":"20130410","count":10},{"time":"20130411","count":3},{"time":"20130412","count":11},{"time":"20130415","count":12},{"time":"20130416","count":11},{"time":"20130417","count":15},{"time":"20130418","count":9},{"time":"20130419","count":12},{"time":"20130421","count":1},{"time":"20130422","count":11},{"time":"20130423","count":12},{"time":"20130424","count":13},{"time":"20130425","count":10},{"time":"20130426","count":20},{"time":"20130429","count":19},{"time":"20130430","count":14},{"time":"20130501","count":11},{"time":"20130502","count":22},{"time":"20130503","count":27},{"time":"20130504","count":1},{"time":"20130506","count":15},{"time":"20130507","count":7},{"time":"20130508","count":6},{"time":"20130509","count":11},{"time":"20130510","count":14},{"time":"20130513","count":14},{"time":"20130514","count":16},{"time":"20130515","count":13},{"time":"20130516","count":13},{"time":"20130517","count":7},{"time":"20130518","count":1},{"time":"20130520","count":9},{"time":"20130521","count":10},{"time":"20130522","count":11},{"time":"20130523","count":7},{"time":"20130524","count":5},{"time":"20130525","count":1},{"time":"20130527","count":5},{"time":"20130528","count":18},{"time":"20130529","count":8},{"time":"20130530","count":10},{"time":"20130531","count":9},{"time":"20130601","count":3},{"time":"20130603","count":21},{"time":"20130604","count":7},{"time":"20130605","count":17},{"time":"20130606","count":12},{"time":"20130607","count":12},{"time":"20130609","count":1},{"time":"20130610","count":18},{"time":"20130611","count":15},{"time":"20130612","count":14},{"time":"20130613","count":5},{"time":"20130614","count":19},{"time":"20130617","count":18},{"time":"20130618","count":9},{"time":"20130619","count":7},{"time":"20130620","count":11},{"time":"20130621","count":8},{"time":"20130622","count":1},{"time":"20130624","count":16},{"time":"20130625","count":7},{"time":"20130626","count":8},{"time":"20130627","count":8},{"time":"20130628","count":8},{"time":"20130701","count":10},{"time":"20130702","count":11},{"time":"20130703","count":9},{"time":"20130704","count":1},{"time":"20130705","count":7},{"time":"20130706","count":1},{"time":"20130708","count":20},{"time":"20130709","count":15},{"time":"20130710","count":16},{"time":"20130711","count":9},{"time":"20130712","count":4},{"time":"20130715","count":13},{"time":"20130716","count":11},{"time":"20130717","count":9},{"time":"20130718","count":11},{"time":"20130719","count":12},{"time":"20130721","count":2},{"time":"20130722","count":15},{"time":"20130723","count":12},{"time":"20130724","count":7},{"time":"20130725","count":18},{"time":"20130726","count":14},{"time":"20130729","count":12},{"time":"20130730","count":10},{"time":"20130731","count":15},{"time":"20130801","count":5},{"time":"20130802","count":12},{"time":"20130804","count":1},{"time":"20130805","count":6},{"time":"20130806","count":13},{"time":"20130807","count":4},{"time":"20130808","count":6},{"time":"20130809","count":15},{"time":"20130811","count":1},{"time":"20130812","count":19},{"time":"20130813","count":8},{"time":"20130814","count":15},{"time":"20130815","count":12},{"time":"20130816","count":8},{"time":"20130819","count":23},{"time":"20130820","count":8},{"time":"20130821","count":18},{"time":"20130822","count":8},{"time":"20130823","count":17},{"time":"20130826","count":8},{"time":"20130827","count":15},{"time":"20130828","count":6},{"time":"20130829","count":9},{"time":"20130830","count":8},{"time":"20130902","count":2},{"time":"20130903","count":3},{"time":"20130904","count":9},{"time":"20130905","count":8},{"time":"20130906","count":16},{"time":"20130908","count":1},{"time":"20130909","count":18},{"time":"20130910","count":7},{"time":"20130911","count":10},{"time":"20130912","count":15},{"time":"20130913","count":25},{"time":"20130916","count":29},{"time":"20130917","count":10},{"time":"20130918","count":8},{"time":"20130919","count":13},{"time":"20130920","count":19},{"time":"20130923","count":12},{"time":"20130924","count":8},{"time":"20130925","count":12},{"time":"20130926","count":35},{"time":"20130927","count":21},{"time":"20130928","count":1},{"time":"20130929","count":1},{"time":"20130930","count":19},{"time":"20131001","count":15},{"time":"20131002","count":14},{"time":"20131003","count":13},{"time":"20131004","count":12},{"time":"20131007","count":13},{"time":"20131008","count":9},{"time":"20131009","count":10},{"time":"20131010","count":9},{"time":"20131011","count":12},{"time":"20131014","count":8},{"time":"20131015","count":14},{"time":"20131016","count":15},{"time":"20131017","count":19},{"time":"20131018","count":13},{"time":"20131020","count":1},{"time":"20131021","count":10},{"time":"20131022","count":13},{"time":"20131023","count":13},{"time":"20131024","count":14},{"time":"20131025","count":13},{"time":"20131026","count":1},{"time":"20131028","count":15},{"time":"20131029","count":9},{"time":"20131030","count":15},{"time":"20131031","count":12},{"time":"20131101","count":10},{"time":"20131104","count":8},{"time":"20131105","count":15},{"time":"20131106","count":13},{"time":"20131107","count":17},{"time":"20131108","count":2},{"time":"20131111","count":15},{"time":"20131112","count":13},{"time":"20131113","count":11},{"time":"20131114","count":10},{"time":"20131115","count":6},{"time":"20131118","count":13},{"time":"20131119","count":5},{"time":"20131120","count":15},{"time":"20131121","count":8},{"time":"20131122","count":12},{"time":"20131125","count":14},{"time":"20131126","count":15},{"time":"20131127","count":17},{"time":"20131128","count":3},{"time":"20131129","count":3},{"time":"20131202","count":22},{"time":"20131203","count":11},{"time":"20131204","count":16},{"time":"20131205","count":11},{"time":"20131206","count":15},{"time":"20131209","count":13},{"time":"20131210","count":21},{"time":"20131211","count":10},{"time":"20131212","count":15},{"time":"20131213","count":14},{"time":"20131216","count":21},{"time":"20131217","count":8},{"time":"20131218","count":8},{"time":"20131219","count":13},{"time":"20131220","count":12},{"time":"20131221","count":1},{"time":"20131222","count":1},{"time":"20131223","count":17},{"time":"20131224","count":9},{"time":"20131225","count":1},{"time":"20131226","count":12},{"time":"20131227","count":15},{"time":"20131228","count":1},{"time":"20131230","count":14},{"time":"20131231","count":11},{"time":"20140102","count":12},{"time":"20140103","count":9},{"time":"20140106","count":15},{"time":"20140107","count":15},{"time":"20140108","count":14},{"time":"20140109","count":10},{"time":"20140110","count":21},{"time":"20140111","count":1},{"time":"20140113","count":12},{"time":"20140114","count":7},{"time":"20140115","count":10},{"time":"20140116","count":10},{"time":"20140117","count":16},{"time":"20140120","count":4},{"time":"20140121","count":11},{"time":"20140122","count":13},{"time":"20140123","count":19},{"time":"20140124","count":13},{"time":"20140127","count":13},{"time":"20140128","count":8},{"time":"20140129","count":8},{"time":"20140130","count":10},{"time":"20140131","count":9},{"time":"20140202","count":2},{"time":"20140203","count":14},{"time":"20140204","count":12},{"time":"20140205","count":10},{"time":"20140206","count":35},{"time":"20140207","count":22},{"time":"20140208","count":1},{"time":"20140209","count":1},{"time":"20140210","count":28},{"time":"20140211","count":15},{"time":"20140212","count":8},{"time":"20140213","count":7},{"time":"20140214","count":16},{"time":"20140216","count":2},{"time":"20140217","count":6},{"time":"20140218","count":9},{"time":"20140219","count":21},{"time":"20140220","count":10},{"time":"20140221","count":15},{"time":"20140223","count":3},{"time":"20140224","count":12},{"time":"20140225","count":6},{"time":"20140226","count":6},{"time":"20140227","count":13},{"time":"20140228","count":5},{"time":"20140301","count":1},{"time":"20140303","count":38},{"time":"20140304","count":38},{"time":"20140305","count":35},{"time":"20140306","count":51},{"time":"20140307","count":24},{"time":"20140308","count":1},{"time":"20140310","count":16},{"time":"20140311","count":12},{"time":"20140312","count":13},{"time":"20140313","count":25},{"time":"20140314","count":4},{"time":"20140316","count":2},{"time":"20140317","count":7},{"time":"20140318","count":16},{"time":"20140319","count":7},{"time":"20140320","count":9},{"time":"20140321","count":12},{"time":"20140323","count":1},{"time":"20140324","count":17},{"time":"20140325","count":12},{"time":"20140326","count":7},{"time":"20140327","count":12},{"time":"20140328","count":8},{"time":"20140329","count":1},{"time":"20140330","count":1},{"time":"20140331","count":17},{"time":"20140401","count":14},{"time":"20140402","count":9},{"time":"20140403","count":12},{"time":"20140404","count":21},{"time":"20140407","count":15},{"time":"20140408","count":12},{"time":"20140409","count":11},{"time":"20140410","count":7},{"time":"20140411","count":21},{"time":"20140414","count":18},{"time":"20140415","count":12},{"time":"20140416","count":17},{"time":"20140417","count":11},{"time":"20140418","count":6},{"time":"20140421","count":15},{"time":"20140422","count":9},{"time":"20140423","count":12},{"time":"20140424","count":12},{"time":"20140425","count":10},{"time":"20140426","count":1},{"time":"20140428","count":9},{"time":"20140429","count":9},{"time":"20140430","count":8},{"time":"20140501","count":6},{"time":"20140502","count":6},{"time":"20140505","count":11},{"time":"20140506","count":8},{"time":"20140507","count":20},{"time":"20140508","count":9},{"time":"20140509","count":12},{"time":"20140510","count":2},{"time":"20140512","count":8},{"time":"20140513","count":15},{"time":"20140514","count":3},{"time":"20140515","count":16},{"time":"20140516","count":16},{"time":"20140519","count":15},{"time":"20140520","count":20},{"time":"20140521","count":16},{"time":"20140522","count":13},{"time":"20140523","count":24},{"time":"20140526","count":4},{"time":"20140527","count":17},{"time":"20140528","count":10},{"time":"20140529","count":12},{"time":"20140530","count":14},{"time":"20140531","count":1},{"time":"20140601","count":1},{"time":"20140602","count":6},{"time":"20140603","count":8},{"time":"20140604","count":13},{"time":"20140605","count":11},{"time":"20140606","count":15},{"time":"20140609","count":10},{"time":"20140610","count":13},{"time":"20140611","count":13},{"time":"20140612","count":12},{"time":"20140613","count":18},{"time":"20140616","count":19},{"time":"20140617","count":14},{"time":"20140618","count":13},{"time":"20140619","count":11},{"time":"20140620","count":18},{"time":"20140621","count":4},{"time":"20140623","count":16},{"time":"20140624","count":17},{"time":"20140625","count":11},{"time":"20140626","count":18},{"time":"20140627","count":12},{"time":"20140630","count":20},{"time":"20140701","count":8},{"time":"20140702","count":17},{"time":"20140703","count":10},{"time":"20140704","count":4},{"time":"20140706","count":1},{"time":"20140707","count":16},{"time":"20140708","count":10},{"time":"20140709","count":11},{"time":"20140710","count":9},{"time":"20140711","count":15},{"time":"20140713","count":1},{"time":"20140714","count":11},{"time":"20140715","count":7},{"time":"20140716","count":5},{"time":"20140717","count":9},{"time":"20140718","count":10},{"time":"20140721","count":18},{"time":"20140722","count":17},{"time":"20140723","count":13},{"time":"20140724","count":19},{"time":"20140725","count":17},{"time":"20140728","count":9},{"time":"20140729","count":6},{"time":"20140730","count":14},{"time":"20140731","count":13},{"time":"20140801","count":9},{"time":"20140804","count":33},{"time":"20140805","count":7},{"time":"20140806","count":10},{"time":"20140807","count":10},{"time":"20140808","count":9},{"time":"20140810","count":1},{"time":"20140811","count":17},{"time":"20140812","count":17},{"time":"20140813","count":24},{"time":"20140814","count":10},{"time":"20140815","count":8},{"time":"20140818","count":16},{"time":"20140819","count":20},{"time":"20140820","count":10},{"time":"20140821","count":17},{"time":"20140822","count":16},{"time":"20140823","count":1},{"time":"20140825","count":19},{"time":"20140826","count":14},{"time":"20140827","count":10},{"time":"20140828","count":5},{"time":"20140829","count":13},{"time":"20140830","count":1},{"time":"20140831","count":1},{"time":"20140901","count":1},{"time":"20140902","count":19},{"time":"20140903","count":34},{"time":"20140904","count":14},{"time":"20140905","count":12},{"time":"20140906","count":1},{"time":"20140908","count":12},{"time":"20140909","count":6},{"time":"20140910","count":9},{"time":"20140911","count":11},{"time":"20140912","count":15},{"time":"20140915","count":12},{"time":"20140916","count":18},{"time":"20140917","count":11},{"time":"20140918","count":17},{"time":"20140919","count":18},{"time":"20140922","count":12},{"time":"20140923","count":17},{"time":"20140924","count":8},{"time":"20140925","count":5},{"time":"20140926","count":8},{"time":"20140929","count":17},{"time":"20140930","count":17},{"time":"20141001","count":14},{"time":"20141002","count":13},{"time":"20141003","count":10},{"time":"20141004","count":1},{"time":"20141006","count":23},{"time":"20141007","count":6},{"time":"20141008","count":20},{"time":"20141009","count":11},{"time":"20141010","count":20},{"time":"20141013","count":5},{"time":"20141014","count":23},{"time":"20141015","count":9},{"time":"20141016","count":12},{"time":"20141017","count":14},{"time":"20141020","count":14},{"time":"20141021","count":13},{"time":"20141022","count":10},{"time":"20141023","count":13},{"time":"20141024","count":14},{"time":"20141027","count":22},{"time":"20141028","count":8},{"time":"20141029","count":21},{"time":"20141030","count":7},{"time":"20141031","count":15},{"time":"20141103","count":32},{"time":"20141104","count":11},{"time":"20141105","count":15},{"time":"20141106","count":9},{"time":"20141107","count":14},{"time":"20141108","count":1},{"time":"20141110","count":22},{"time":"20141111","count":11},{"time":"20141112","count":9},{"time":"20141113","count":10},{"time":"20141114","count":8},{"time":"20141117","count":16},{"time":"20141118","count":13},{"time":"20141119","count":19},{"time":"20141120","count":22},{"time":"20141121","count":12},{"time":"20141123","count":5},{"time":"20141124","count":17},{"time":"20141125","count":13},{"time":"20141126","count":18},{"time":"20141127","count":1},{"time":"20141128","count":8},{"time":"20141129","count":1},{"time":"20141201","count":16},{"time":"20141202","count":16},{"time":"20141203","count":18},{"time":"20141204","count":13},{"time":"20141205","count":14},{"time":"20141208","count":13},{"time":"20141209","count":16},{"time":"20141210","count":9},{"time":"20141211","count":22},{"time":"20141212","count":8},{"time":"20141215","count":23},{"time":"20141216","count":12},{"time":"20141217","count":15},{"time":"20141218","count":17},{"time":"20141219","count":10},{"time":"20141222","count":11},{"time":"20141223","count":15},{"time":"20141224","count":14},{"time":"20141226","count":2},{"time":"20141227","count":1},{"time":"20141228","count":1},{"time":"20141229","count":25},{"time":"20141230","count":12},{"time":"20141231","count":15},{"time":"20150101","count":1},{"time":"20150102","count":6},{"time":"20150103","count":1},{"time":"20150105","count":13},{"time":"20150106","count":13},{"time":"20150107","count":8},{"time":"20150108","count":14},{"time":"20150109","count":16},{"time":"20150111","count":1},{"time":"20150112","count":14},{"time":"20150113","count":14},{"time":"20150114","count":14},{"time":"20150115","count":16},{"time":"20150116","count":27},{"time":"20150119","count":6},{"time":"20150120","count":10},{"time":"20150121","count":10},{"time":"20150122","count":16},{"time":"20150123","count":25},{"time":"20150126","count":18},{"time":"20150127","count":18},{"time":"20150128","count":12},{"time":"20150129","count":13},{"time":"20150130","count":20},{"time":"20150131","count":1},{"time":"20150202","count":20},{"time":"20150203","count":10},{"time":"20150204","count":21},{"time":"20150205","count":16},{"time":"20150206","count":17},{"time":"20150207","count":6},{"time":"20150208","count":3},{"time":"20150209","count":27},{"time":"20150210","count":24},{"time":"20150211","count":8},{"time":"20150212","count":22},{"time":"20150213","count":16},{"time":"20150216","count":17},{"time":"20150217","count":47},{"time":"20150218","count":50},{"time":"20150219","count":46},{"time":"20150220","count":42},{"time":"20150221","count":8},{"time":"20150223","count":60},{"time":"20150224","count":20},{"time":"20150225","count":16},{"time":"20150226","count":28},{"time":"20150227","count":15},{"time":"20150301","count":1},{"time":"20150302","count":36},{"time":"20150303","count":18},{"time":"20150304","count":19},{"time":"20150305","count":16},{"time":"20150306","count":15},{"time":"20150307","count":1},{"time":"20150308","count":2},{"time":"20150309","count":19},{"time":"20150310","count":15},{"time":"20150311","count":7},{"time":"20150312","count":10},{"time":"20150313","count":11},{"time":"20150314","count":1},{"time":"20150316","count":25},{"time":"20150317","count":13},{"time":"20150318","count":17},{"time":"20150319","count":16},{"time":"20150320","count":17},{"time":"20150321","count":1},{"time":"20150322","count":1},{"time":"20150323","count":13},{"time":"20150324","count":13},{"time":"20150325","count":10},{"time":"20150326","count":12},{"time":"20150327","count":19},{"time":"20150329","count":1},{"time":"20150330","count":23},{"time":"20150331","count":24},{"time":"20150401","count":19},{"time":"20150402","count":20},{"time":"20150403","count":18},{"time":"20150404","count":4},{"time":"20150406","count":18},{"time":"20150407","count":24},{"time":"20150408","count":7},{"time":"20150409","count":12},{"time":"20150410","count":29},{"time":"20150411","count":1},{"time":"20150412","count":41},{"time":"20150413","count":32},{"time":"20150414","count":10},{"time":"20150415","count":24},{"time":"20150416","count":17},{"time":"20150417","count":21},{"time":"20150418","count":3},{"time":"20150420","count":10},{"time":"20150421","count":25},{"time":"20150422","count":15},{"time":"20150423","count":12},{"time":"20150424","count":11},{"time":"20150425","count":7},{"time":"20150427","count":9},{"time":"20150428","count":20},{"time":"20150429","count":18},{"time":"20150430","count":14},{"time":"20150501","count":10},{"time":"20150503","count":3},{"time":"20150504","count":12},{"time":"20150505","count":26},{"time":"20150506","count":14},{"time":"20150507","count":22},{"time":"20150508","count":12},{"time":"20150511","count":15},{"time":"20150512","count":12},{"time":"20150513","count":10},{"time":"20150514","count":9},{"time":"20150515","count":12},{"time":"20150516","count":3},{"time":"20150518","count":7},{"time":"20150519","count":15},{"time":"20150520","count":10},{"time":"20150521","count":12},{"time":"20150522","count":14},{"time":"20150524","count":2},{"time":"20150525","count":7},{"time":"20150526","count":13},{"time":"20150527","count":12},{"time":"20150528","count":20},{"time":"20150529","count":12},{"time":"20150530","count":1},{"time":"20150601","count":15},{"time":"20150602","count":8},{"time":"20150603","count":14},{"time":"20150604","count":14},{"time":"20150605","count":13},{"time":"20150608","count":8},{"time":"20150609","count":18},{"time":"20150610","count":7},{"time":"20150611","count":16},{"time":"20150612","count":16},{"time":"20150613","count":4},{"time":"20150614","count":1},{"time":"20150615","count":19},{"time":"20150616","count":8},{"time":"20150617","count":20},{"time":"20150618","count":74},{"time":"20150619","count":12},{"time":"20150622","count":16},{"time":"20150623","count":10},{"time":"20150624","count":11},{"time":"20150625","count":15},{"time":"20150626","count":16},{"time":"20150629","count":16},{"time":"20150630","count":15},{"time":"20150701","count":17},{"time":"20150702","count":11},{"time":"20150703","count":3},{"time":"20150704","count":2},{"time":"20150706","count":26},{"time":"20150707","count":20},{"time":"20150708","count":24},{"time":"20150709","count":12},{"time":"20150710","count":18},{"time":"20150713","count":21},{"time":"20150714","count":20},{"time":"20150715","count":26},{"time":"20150716","count":15},{"time":"20150717","count":18},{"time":"20150720","count":15},{"time":"20150721","count":15},{"time":"20150722","count":20},{"time":"20150723","count":17},{"time":"20150724","count":17},{"time":"20150727","count":21},{"time":"20150728","count":34},{"time":"20150729","count":19},{"time":"20150730","count":17},{"time":"20150731","count":21},{"time":"20150802","count":1},{"time":"20150803","count":25},{"time":"20150804","count":18},{"time":"20150805","count":20},{"time":"20150806","count":15},{"time":"20150807","count":17},{"time":"20150808","count":1},{"time":"20150810","count":8},{"time":"20150811","count":15},{"time":"20150812","count":11},{"time":"20150813","count":14},{"time":"20150814","count":16},{"time":"20150815","count":5},{"time":"20150817","count":12},{"time":"20150818","count":8},{"time":"20150819","count":18},{"time":"20150820","count":12},{"time":"20150821","count":22},{"time":"20150824","count":15},{"time":"20150825","count":14},{"time":"20150826","count":17},{"time":"20150827","count":19},{"time":"20150828","count":13},{"time":"20150829","count":1},{"time":"20150831","count":25},{"time":"20150901","count":11},{"time":"20150902","count":16},{"time":"20150903","count":17},{"time":"20150904","count":14},{"time":"20150907","count":8},{"time":"20150908","count":25},{"time":"20150909","count":32},{"time":"20150910","count":27},{"time":"20150911","count":38},{"time":"20150912","count":2},{"time":"20150914","count":16},{"time":"20150915","count":10},{"time":"20150916","count":21},{"time":"20150917","count":12},{"time":"20150918","count":11},{"time":"20150919","count":1},{"time":"20150920","count":1},{"time":"20150921","count":24},{"time":"20150922","count":15},{"time":"20150923","count":28},{"time":"20150924","count":18},{"time":"20150925","count":11},{"time":"20150926","count":1},{"time":"20150928","count":22},{"time":"20150929","count":18},{"time":"20150930","count":14},{"time":"20151001","count":21},{"time":"20151002","count":9},{"time":"20151004","count":1},{"time":"20151005","count":20},{"time":"20151006","count":22},{"time":"20151007","count":8},{"time":"20151008","count":33},{"time":"20151009","count":42},{"time":"20151012","count":29},{"time":"20151013","count":14},{"time":"20151014","count":13},{"time":"20151015","count":9},{"time":"20151016","count":20},{"time":"20151019","count":16},{"time":"20151020","count":26},{"time":"20151021","count":15},{"time":"20151022","count":14},{"time":"20151023","count":33},{"time":"20151026","count":29},{"time":"20151027","count":29},{"time":"20151028","count":18},{"time":"20151029","count":18},{"time":"20151030","count":16},{"time":"20151031","count":1},{"time":"20151101","count":2},{"time":"20151102","count":16},{"time":"20151103","count":14},{"time":"20151104","count":23},{"time":"20151105","count":27},{"time":"20151106","count":25},{"time":"20151107","count":1},{"time":"20151109","count":27},{"time":"20151110","count":34},{"time":"20151111","count":13},{"time":"20151112","count":25},{"time":"20151113","count":38},{"time":"20151114","count":2},{"time":"20151115","count":1},{"time":"20151116","count":28},{"time":"20151117","count":27},{"time":"20151118","count":17},{"time":"20151119","count":28},{"time":"20151120","count":22},{"time":"20151122","count":1},{"time":"20151123","count":21},{"time":"20151124","count":13},{"time":"20151125","count":21},{"time":"20151126","count":2},{"time":"20151127","count":8},{"time":"20151128","count":1},{"time":"20151129","count":2},{"time":"20151130","count":17},{"time":"20151201","count":29},{"time":"20151202","count":28},{"time":"20151203","count":15},{"time":"20151204","count":21},{"time":"20151206","count":2},{"time":"20151207","count":27},{"time":"20151208","count":19},{"time":"20151209","count":14},{"time":"20151210","count":42},{"time":"20151211","count":14},{"time":"20151212","count":1},{"time":"20151213","count":1},{"time":"20151214","count":26},{"time":"20151215","count":23},{"time":"20151216","count":24},{"time":"20151217","count":23},{"time":"20151218","count":15},{"time":"20151219","count":3},{"time":"20151221","count":20},{"time":"20151222","count":13},{"time":"20151223","count":30},{"time":"20151224","count":14},{"time":"20151225","count":1},{"time":"20151226","count":1},{"time":"20151228","count":14},{"time":"20151229","count":23},{"time":"20151230","count":22},{"time":"20151231","count":20},{"time":"20160101","count":1},{"time":"20160102","count":1},{"time":"20160103","count":1},{"time":"20160104","count":22},{"time":"20160105","count":32},{"time":"20160106","count":21},{"time":"20160107","count":19},{"time":"20160108","count":27},{"time":"20160111","count":23},{"time":"20160112","count":16},{"time":"20160113","count":18},{"time":"20160114","count":15},{"time":"20160115","count":45},{"time":"20160117","count":1},{"time":"20160118","count":12},{"time":"20160119","count":18},{"time":"20160120","count":22},{"time":"20160121","count":17},{"time":"20160122","count":20},{"time":"20160123","count":2},{"time":"20160124","count":1},{"time":"20160125","count":38},{"time":"20160126","count":15},{"time":"20160127","count":15},{"time":"20160128","count":22},{"time":"20160129","count":25},{"time":"20160130","count":2},{"time":"20160131","count":1},{"time":"20160201","count":21},{"time":"20160202","count":24},{"time":"20160203","count":18},{"time":"20160204","count":55},{"time":"20160205","count":138},{"time":"20160206","count":15},{"time":"20160207","count":7},{"time":"20160208","count":152},{"time":"20160209","count":68},{"time":"20160210","count":32},{"time":"20160211","count":20},{"time":"20160212","count":19},{"time":"20160214","count":1},{"time":"20160215","count":11},{"time":"20160216","count":29},{"time":"20160217","count":15},{"time":"20160218","count":17},{"time":"20160219","count":25},{"time":"20160220","count":17},{"time":"20160221","count":3},{"time":"20160222","count":23},{"time":"20160223","count":18},{"time":"20160224","count":16},{"time":"20160225","count":25},{"time":"20160226","count":20},{"time":"20160227","count":2},{"time":"20160229","count":19},{"time":"20160301","count":340},{"time":"20160302","count":12},{"time":"20160303","count":21},{"time":"20160304","count":20},{"time":"20160306","count":1},{"time":"20160307","count":12},{"time":"20160308","count":18},{"time":"20160309","count":16},{"time":"20160310","count":10},{"time":"20160311","count":15},{"time":"20160314","count":16},{"time":"20160315","count":30},{"time":"20160316","count":15},{"time":"20160317","count":17},{"time":"20160318","count":14},{"time":"20160321","count":26},{"time":"20160322","count":14},{"time":"20160323","count":12},{"time":"20160324","count":15},{"time":"20160325","count":9},{"time":"20160328","count":27},{"time":"20160329","count":13},{"time":"20160330","count":27},{"time":"20160331","count":19},{"time":"20160401","count":22},{"time":"20160402","count":1},{"time":"20160404","count":26},{"time":"20160405","count":21},{"time":"20160406","count":16},{"time":"20160407","count":30},{"time":"20160408","count":15},{"time":"20160411","count":32},{"time":"20160412","count":24},{"time":"20160413","count":28},{"time":"20160414","count":15},{"time":"20160415","count":22},{"time":"20160418","count":28},{"time":"20160419","count":19},{"time":"20160420","count":24},{"time":"20160421","count":19},{"time":"20160422","count":19},{"time":"20160425","count":18},{"time":"20160426","count":21},{"time":"20160427","count":22},{"time":"20160428","count":22},{"time":"20160429","count":17},{"time":"20160502","count":22},{"time":"20160503","count":24},{"time":"20160504","count":34},{"time":"20160505","count":21},{"time":"20160506","count":22},{"time":"20160507","count":4},{"time":"20160509","count":20},{"time":"20160510","count":19},{"time":"20160511","count":15},{"time":"20160512","count":28},{"time":"20160513","count":28},{"time":"20160516","count":34},{"time":"20160517","count":33},{"time":"20160518","count":21},{"time":"20160519","count":14},{"time":"20160520","count":35},{"time":"20160521","count":1},{"time":"20160523","count":16},{"time":"20160524","count":16},{"time":"20160525","count":12},{"time":"20160526","count":20},{"time":"20160527","count":29},{"time":"20160529","count":2},{"time":"20160530","count":15},{"time":"20160531","count":41},{"time":"20160601","count":24},{"time":"20160602","count":19},{"time":"20160603","count":38},{"time":"20160604","count":1},{"time":"20160605","count":1},{"time":"20160606","count":20},{"time":"20160607","count":24},{"time":"20160608","count":14},{"time":"20160609","count":32},{"time":"20160610","count":26},{"time":"20160613","count":30},{"time":"20160614","count":13},{"time":"20160615","count":53},{"time":"20160616","count":14},{"time":"20160617","count":30},{"time":"20160618","count":1},{"time":"20160619","count":1},{"time":"20160620","count":28},{"time":"20160621","count":41},{"time":"20160622","count":15},{"time":"20160623","count":15},{"time":"20160624","count":18},{"time":"20160625","count":1},{"time":"20160626","count":1},{"time":"20160627","count":22},{"time":"20160628","count":44},{"time":"20160629","count":13},{"time":"20160630","count":23},{"time":"20160701","count":18},{"time":"20160704","count":11},{"time":"20160705","count":29},{"time":"20160706","count":29},{"time":"20160707","count":18},{"time":"20160708","count":21},{"time":"20160709","count":1},{"time":"20160710","count":1},{"time":"20160711","count":28},{"time":"20160712","count":18},{"time":"20160713","count":14},{"time":"20160714","count":26},{"time":"20160715","count":21},{"time":"20160716","count":1},{"time":"20160718","count":22},{"time":"20160719","count":21},{"time":"20160720","count":24},{"time":"20160721","count":59},{"time":"20160722","count":24},{"time":"20160725","count":23},{"time":"20160726","count":25},{"time":"20160727","count":24},{"time":"20160728","count":25},{"time":"20160729","count":27},{"time":"20160731","count":1},{"time":"20160801","count":31},{"time":"20160802","count":35},{"time":"20160803","count":16},{"time":"20160804","count":48},{"time":"20160805","count":32},{"time":"20160808","count":104},{"time":"20160809","count":37},{"time":"20160810","count":18},{"time":"20160811","count":19},{"time":"20160812","count":23},{"time":"20160813","count":2},{"time":"20160815","count":16},{"time":"20160816","count":17},{"time":"20160817","count":31},{"time":"20160818","count":13},{"time":"20160819","count":21},{"time":"20160820","count":4},{"time":"20160821","count":1},{"time":"20160822","count":23},{"time":"20160823","count":27},{"time":"20160824","count":32},{"time":"20160825","count":29},{"time":"20160826","count":29},{"time":"20160828","count":2},{"time":"20160829","count":28},{"time":"20160830","count":24},{"time":"20160831","count":38},{"time":"20160901","count":43},{"time":"20160902","count":24},{"time":"20160903","count":1},{"time":"20160904","count":2},{"time":"20160905","count":22},{"time":"20160906","count":41},{"time":"20160907","count":49},{"time":"20160908","count":27},{"time":"20160909","count":18},{"time":"20160910","count":2},{"time":"20160911","count":1},{"time":"20160912","count":21},{"time":"20160913","count":20},{"time":"20160914","count":29},{"time":"20160915","count":48},{"time":"20160916","count":19},{"time":"20160917","count":2},{"time":"20160918","count":1},{"time":"20160919","count":30},{"time":"20160920","count":29},{"time":"20160921","count":22},{"time":"20160922","count":19},{"time":"20160923","count":18},{"time":"20160924","count":4},{"time":"20160925","count":1},{"time":"20160926","count":18},{"time":"20160927","count":28},{"time":"20160928","count":17},{"time":"20160929","count":35},{"time":"20160930","count":16},{"time":"20161001","count":1},{"time":"20161002","count":2},{"time":"20161003","count":29},{"time":"20161004","count":71},{"time":"20161005","count":26},{"time":"20161006","count":27},{"time":"20161007","count":46},{"time":"20161008","count":1},{"time":"20161010","count":40},{"time":"20161011","count":30},{"time":"20161012","count":34},{"time":"20161013","count":33},{"time":"20161014","count":25},{"time":"20161015","count":1},{"time":"20161017","count":37},{"time":"20161018","count":25},{"time":"20161019","count":28},{"time":"20161020","count":31},{"time":"20161021","count":18},{"time":"20161023","count":1},{"time":"20161024","count":26},{"time":"20161025","count":26},{"time":"20161026","count":25},{"time":"20161027","count":31},{"time":"20161028","count":27},{"time":"20161029","count":1},{"time":"20161031","count":18},{"time":"20161101","count":13},{"time":"20161102","count":27},{"time":"20161103","count":14},{"time":"20161104","count":27},{"time":"20161106","count":10},{"time":"20161107","count":19},{"time":"20161108","count":28},{"time":"20161109","count":22},{"time":"20161110","count":18},{"time":"20161111","count":15},{"time":"20161113","count":1},{"time":"20161114","count":26},{"time":"20161115","count":10},{"time":"20161116","count":20},{"time":"20161117","count":19},{"time":"20161118","count":24},{"time":"20161120","count":2},{"time":"20161121","count":18},{"time":"20161122","count":20},{"time":"20161123","count":44},{"time":"20161124","count":8},{"time":"20161125","count":7},{"time":"20161126","count":3},{"time":"20161127","count":2},{"time":"20161128","count":29},{"time":"20161129","count":15},{"time":"20161130","count":19},{"time":"20161201","count":19},{"time":"20161202","count":14},{"time":"20161204","count":2},{"time":"20161205","count":16},{"time":"20161206","count":19},{"time":"20161207","count":12},{"time":"20161208","count":20},{"time":"20161209","count":27},{"time":"20161211","count":1},{"time":"20161212","count":18},{"time":"20161213","count":20},{"time":"20161214","count":23},{"time":"20161215","count":26},{"time":"20161216","count":14},{"time":"20161218","count":1},{"time":"20161219","count":25},{"time":"20161220","count":25},{"time":"20161221","count":22},{"time":"20161222","count":32},{"time":"20161223","count":41},{"time":"20161225","count":3},{"time":"20161226","count":7},{"time":"20161227","count":33},{"time":"20161228","count":29},{"time":"20161229","count":35},{"time":"20161230","count":20},{"time":"20161231","count":3},{"time":"20170102","count":6},{"time":"20170103","count":32},{"time":"20170104","count":29},{"time":"20170105","count":17},{"time":"20170106","count":21},{"time":"20170107","count":1},{"time":"20170108","count":2},{"time":"20170109","count":16},{"time":"20170110","count":18},{"time":"20170111","count":19},{"time":"20170112","count":26},{"time":"20170113","count":14},{"time":"20170115","count":2},{"time":"20170116","count":18},{"time":"20170117","count":23},{"time":"20170118","count":24},{"time":"20170119","count":30},{"time":"20170120","count":19},{"time":"20170121","count":3},{"time":"20170122","count":3},{"time":"20170123","count":23},{"time":"20170124","count":15},{"time":"20170125","count":24},{"time":"20170126","count":13},{"time":"20170127","count":16},{"time":"20170128","count":5},{"time":"20170130","count":22},{"time":"20170131","count":30},{"time":"20170201","count":25},{"time":"20170202","count":23},{"time":"20170203","count":23},{"time":"20170204","count":2},{"time":"20170205","count":2},{"time":"20170206","count":11},{"time":"20170207","count":19},{"time":"20170208","count":14},{"time":"20170209","count":24},{"time":"20170210","count":47},{"time":"20170211","count":15},{"time":"20170212","count":7},{"time":"20170213","count":24},{"time":"20170214","count":16},{"time":"20170215","count":24},{"time":"20170216","count":20},{"time":"20170217","count":21},{"time":"20170218","count":4},{"time":"20170220","count":19},{"time":"20170221","count":17},{"time":"20170222","count":20},{"time":"20170223","count":17},{"time":"20170224","count":16},{"time":"20170225","count":2},{"time":"20170227","count":23},{"time":"20170228","count":13},{"time":"20170301","count":23},{"time":"20170302","count":13},{"time":"20170303","count":22},{"time":"20170304","count":2},{"time":"20170306","count":10},{"time":"20170307","count":14},{"time":"20170308","count":15},{"time":"20170309","count":15},{"time":"20170310","count":21},{"time":"20170311","count":1},{"time":"20170312","count":2},{"time":"20170313","count":16},{"time":"20170314","count":21},{"time":"20170315","count":18},{"time":"20170316","count":27},{"time":"20170317","count":12},{"time":"20170320","count":22},{"time":"20170321","count":19},{"time":"20170322","count":24},{"time":"20170323","count":26},{"time":"20170324","count":21},{"time":"20170325","count":3},{"time":"20170326","count":2},{"time":"20170327","count":21},{"time":"20170328","count":25},{"time":"20170329","count":25},{"time":"20170330","count":22},{"time":"20170331","count":20},{"time":"20170401","count":2},{"time":"20170402","count":4},{"time":"20170403","count":19},{"time":"20170404","count":22},{"time":"20170405","count":10},{"time":"20170406","count":16},{"time":"20170407","count":21},{"time":"20170408","count":1},{"time":"20170410","count":22},{"time":"20170411","count":19},{"time":"20170412","count":27},{"time":"20170413","count":13},{"time":"20170414","count":20},{"time":"20170417","count":23},{"time":"20170418","count":63},{"time":"20170419","count":26},{"time":"20170420","count":22},{"time":"20170421","count":15},{"time":"20170423","count":3},{"time":"20170424","count":25},{"time":"20170425","count":20},{"time":"20170426","count":20},{"time":"20170427","count":23},{"time":"20170428","count":22},{"time":"20170429","count":1},{"time":"20170430","count":1},{"time":"20170501","count":9},{"time":"20170502","count":12},{"time":"20170503","count":28},{"time":"20170504","count":17},{"time":"20170505","count":14},{"time":"20170506","count":1},{"time":"20170507","count":1},{"time":"20170508","count":32},{"time":"20170509","count":28},{"time":"20170510","count":11},{"time":"20170511","count":15},{"time":"20170512","count":14},{"time":"20170513","count":3},{"time":"20170514","count":1},{"time":"20170515","count":13},{"time":"20170516","count":18},{"time":"20170517","count":20},{"time":"20170518","count":22},{"time":"20170519","count":20},{"time":"20170521","count":4},{"time":"20170522","count":13},{"time":"20170523","count":21},{"time":"20170524","count":19},{"time":"20170525","count":23},{"time":"20170526","count":23},{"time":"20170528","count":2},{"time":"20170529","count":11},{"time":"20170530","count":25},{"time":"20170531","count":51},{"time":"20170601","count":26},{"time":"20170602","count":26},{"time":"20170603","count":3},{"time":"20170605","count":13},{"time":"20170606","count":31},{"time":"20170607","count":25},{"time":"20170608","count":21},{"time":"20170609","count":18},{"time":"20170610","count":1},{"time":"20170611","count":1},{"time":"20170612","count":22},{"time":"20170613","count":25},{"time":"20170614","count":24},{"time":"20170615","count":23},{"time":"20170616","count":10},{"time":"20170618","count":1},{"time":"20170619","count":25},{"time":"20170620","count":31},{"time":"20170621","count":22},{"time":"20170622","count":25},{"time":"20170623","count":28},{"time":"20170624","count":1},{"time":"20170625","count":2},{"time":"20170626","count":12},{"time":"20170627","count":23},{"time":"20170628","count":17},{"time":"20170629","count":19},{"time":"20170630","count":22},{"time":"20170701","count":1},{"time":"20170703","count":18},{"time":"20170704","count":5},{"time":"20170705","count":21},{"time":"20170706","count":32},{"time":"20170707","count":29},{"time":"20170708","count":1},{"time":"20170709","count":5},{"time":"20170710","count":21},{"time":"20170711","count":21},{"time":"20170712","count":27},{"time":"20170713","count":24},{"time":"20170714","count":18},{"time":"20170715","count":3},{"time":"20170717","count":14},{"time":"20170718","count":21},{"time":"20170719","count":28},{"time":"20170720","count":33},{"time":"20170721","count":22},{"time":"20170722","count":2},{"time":"20170723","count":1},{"time":"20170724","count":13},{"time":"20170725","count":26},{"time":"20170726","count":24},{"time":"20170727","count":19},{"time":"20170728","count":19},{"time":"20170730","count":2},{"time":"20170731","count":24},{"time":"20170801","count":15},{"time":"20170802","count":16},{"time":"20170803","count":23},{"time":"20170804","count":42},{"time":"20170806","count":1},{"time":"20170807","count":16},{"time":"20170808","count":23},{"time":"20170809","count":32},{"time":"20170810","count":15},{"time":"20170811","count":27},{"time":"20170812","count":4},{"time":"20170813","count":2},{"time":"20170814","count":33},{"time":"20170815","count":9},{"time":"20170816","count":12},{"time":"20170817","count":22},{"time":"20170818","count":19},{"time":"20170821","count":15},{"time":"20170822","count":29},{"time":"20170823","count":23},{"time":"20170824","count":19},{"time":"20170825","count":16},{"time":"20170826","count":2},{"time":"20170827","count":2},{"time":"20170828","count":27},{"time":"20170829","count":30},{"time":"20170830","count":29},{"time":"20170831","count":10},{"time":"20170901","count":14},{"time":"20170903","count":1},{"time":"20170904","count":10},{"time":"20170905","count":22},{"time":"20170906","count":19},{"time":"20170907","count":23},{"time":"20170908","count":28},{"time":"20170909","count":1},{"time":"20170911","count":10},{"time":"20170912","count":17},{"time":"20170913","count":19},{"time":"20170914","count":58},{"time":"20170915","count":22},{"time":"20170916","count":1},{"time":"20170918","count":14},{"time":"20170919","count":20},{"time":"20170920","count":23},{"time":"20170921","count":13},{"time":"20170922","count":24},{"time":"20170925","count":16},{"time":"20170926","count":22},{"time":"20170927","count":18},{"time":"20170928","count":33},{"time":"20170929","count":18},{"time":"20170930","count":13},{"time":"20171001","count":1},{"time":"20171002","count":13},{"time":"20171003","count":10},{"time":"20171004","count":17},{"time":"20171005","count":20},{"time":"20171006","count":15},{"time":"20171007","count":3},{"time":"20171008","count":6},{"time":"20171009","count":18},{"time":"20171010","count":23},{"time":"20171011","count":17},{"time":"20171012","count":33},{"time":"20171013","count":22},{"time":"20171014","count":4},{"time":"20171016","count":20},{"time":"20171017","count":13},{"time":"20171018","count":23},{"time":"20171019","count":15},{"time":"20171020","count":16},{"time":"20171021","count":3},{"time":"20171022","count":3},{"time":"20171023","count":15},{"time":"20171024","count":20},{"time":"20171025","count":18},{"time":"20171026","count":27},{"time":"20171027","count":18},{"time":"20171028","count":1},{"time":"20171030","count":21},{"time":"20171031","count":22},{"time":"20171101","count":29},{"time":"20171102","count":25},{"time":"20171103","count":22},{"time":"20171104","count":3},{"time":"20171105","count":1},{"time":"20171106","count":16},{"time":"20171107","count":22},{"time":"20171108","count":14},{"time":"20171109","count":19},{"time":"20171110","count":27},{"time":"20171111","count":3},{"time":"20171113","count":26},{"time":"20171114","count":15},{"time":"20171115","count":15},{"time":"20171116","count":14},{"time":"20171117","count":21},{"time":"20171118","count":3},{"time":"20171119","count":2},{"time":"20171120","count":17},{"time":"20171121","count":38},{"time":"20171122","count":20},{"time":"20171123","count":12},{"time":"20171124","count":18},{"time":"20171125","count":1},{"time":"20171126","count":2},{"time":"20171127","count":17},{"time":"20171128","count":18},{"time":"20171129","count":22},{"time":"20171130","count":7},{"time":"20171201","count":13},{"time":"20171204","count":19},{"time":"20171205","count":24},{"time":"20171206","count":9},{"time":"20171207","count":19},{"time":"20171208","count":22},{"time":"20171209","count":3},{"time":"20171210","count":1},{"time":"20171211","count":23},{"time":"20171212","count":26},{"time":"20171213","count":17},{"time":"20171214","count":38},{"time":"20171215","count":39},{"time":"20171217","count":2},{"time":"20171218","count":22},{"time":"20171219","count":23},{"time":"20171220","count":33},{"time":"20171221","count":24},{"time":"20171222","count":33},{"time":"20171223","count":7},{"time":"20171225","count":8},{"time":"20171226","count":18},{"time":"20171227","count":26},{"time":"20171228","count":19},{"time":"20171229","count":18},{"time":"20171230","count":4},{"time":"20171231","count":2},{"time":"20180101","count":2},{"time":"20180102","count":13},{"time":"20180103","count":22},{"time":"20180104","count":34},{"time":"20180105","count":35},{"time":"20180106","count":5},{"time":"20180107","count":3},{"time":"20180108","count":14},{"time":"20180109","count":15},{"time":"20180110","count":31},{"time":"20180111","count":23},{"time":"20180112","count":24},{"time":"20180115","count":31},{"time":"20180116","count":21},{"time":"20180117","count":43},{"time":"20180118","count":25},{"time":"20180119","count":19},{"time":"20180120","count":6},{"time":"20180121","count":3},{"time":"20180122","count":18},{"time":"20180123","count":17},{"time":"20180124","count":16},{"time":"20180125","count":27},{"time":"20180126","count":16},{"time":"20180127","count":1},{"time":"20180128","count":3},{"time":"20180129","count":14},{"time":"20180130","count":74},{"time":"20180131","count":43},{"time":"20180201","count":29},{"time":"20180202","count":29},{"time":"20180203","count":6},{"time":"20180204","count":2},{"time":"20180205","count":14},{"time":"20180206","count":24},{"time":"20180207","count":23},{"time":"20180208","count":34},{"time":"20180209","count":16},{"time":"20180210","count":1},{"time":"20180211","count":2},{"time":"20180212","count":17},{"time":"20180213","count":31},{"time":"20180214","count":21},{"time":"20180215","count":16},{"time":"20180216","count":31},{"time":"20180217","count":7},{"time":"20180218","count":2},{"time":"20180219","count":38},{"time":"20180220","count":23},{"time":"20180221","count":19},{"time":"20180222","count":20},{"time":"20180223","count":23},{"time":"20180224","count":4},{"time":"20180226","count":32},{"time":"20180227","count":24},{"time":"20180228","count":26},{"time":"20180301","count":23},{"time":"20180302","count":24},{"time":"20180303","count":5},{"time":"20180304","count":4},{"time":"20180305","count":30},{"time":"20180306","count":24},{"time":"20180307","count":31},{"time":"20180308","count":38},{"time":"20180309","count":34},{"time":"20180310","count":9},{"time":"20180311","count":1},{"time":"20180312","count":26},{"time":"20180313","count":22},{"time":"20180314","count":23},{"time":"20180315","count":39},{"time":"20180316","count":46},{"time":"20180317","count":5},{"time":"20180318","count":3},{"time":"20180319","count":21},{"time":"20180320","count":42},{"time":"20180321","count":33},{"time":"20180322","count":23},{"time":"20180323","count":30},{"time":"20180324","count":3},{"time":"20180325","count":2},{"time":"20180326","count":55},{"time":"20180327","count":45},{"time":"20180328","count":50},{"time":"20180329","count":50},{"time":"20180330","count":43},{"time":"20180331","count":8},{"time":"20180401","count":2},{"time":"20180402","count":49},{"time":"20180403","count":45},{"time":"20180404","count":50},{"time":"20180405","count":45},{"time":"20180406","count":57},{"time":"20180407","count":3},{"time":"20180408","count":7},{"time":"20180409","count":43},{"time":"20180410","count":59},{"time":"20180411","count":32},{"time":"20180412","count":34},{"time":"20180413","count":48},{"time":"20180414","count":25},{"time":"20180415","count":1},{"time":"20180416","count":24},{"time":"20180417","count":42},{"time":"20180418","count":51},{"time":"20180419","count":52},{"time":"20180420","count":58},{"time":"20180421","count":16},{"time":"20180422","count":3},{"time":"20180423","count":62},{"time":"20180424","count":39},{"time":"20180425","count":48},{"time":"20180426","count":39},{"time":"20180427","count":63},{"time":"20180428","count":10},{"time":"20180429","count":7},{"time":"20180430","count":50},{"time":"20180501","count":46},{"time":"20180502","count":29},{"time":"20180503","count":31},{"time":"20180504","count":42},{"time":"20180505","count":11},{"time":"20180506","count":1},{"time":"20180507","count":38},{"time":"20180508","count":31},{"time":"20180509","count":31},{"time":"20180510","count":34},{"time":"20180511","count":47},{"time":"20180512","count":5},{"time":"20180513","count":1},{"time":"20180514","count":34},{"time":"20180515","count":31},{"time":"20180516","count":33},{"time":"20180517","count":48},{"time":"20180518","count":45},{"time":"20180519","count":3},{"time":"20180520","count":6},{"time":"20180521","count":35},{"time":"20180522","count":44},{"time":"20180523","count":29},{"time":"20180524","count":26},{"time":"20180525","count":41},{"time":"20180526","count":3},{"time":"20180527","count":2},{"time":"20180528","count":16},{"time":"20180529","count":126},{"time":"20180530","count":27},{"time":"20180531","count":16},{"time":"20180601","count":21},{"time":"20180602","count":2},{"time":"20180603","count":1},{"time":"20180604","count":26},{"time":"20180605","count":24},{"time":"20180606","count":28},{"time":"20180607","count":29},{"time":"20180608","count":30},{"time":"20180609","count":5},{"time":"20180610","count":3},{"time":"20180611","count":24},{"time":"20180612","count":28},{"time":"20180613","count":30},{"time":"20180614","count":22},{"time":"20180615","count":27},{"time":"20180616","count":2},{"time":"20180617","count":3},{"time":"20180618","count":21},{"time":"20180619","count":37},{"time":"20180620","count":38},{"time":"20180621","count":36},{"time":"20180622","count":29},{"time":"20180623","count":2},{"time":"20180625","count":33},{"time":"20180626","count":21},{"time":"20180627","count":26},{"time":"20180628","count":26},{"time":"20180629","count":31},{"time":"20180630","count":2},{"time":"20180701","count":1},{"time":"20180702","count":44},{"time":"20180703","count":19},{"time":"20180704","count":16},{"time":"20180705","count":28},{"time":"20180706","count":26},{"time":"20180707","count":1},{"time":"20180708","count":1},{"time":"20180709","count":34},{"time":"20180710","count":27},{"time":"20180711","count":12},{"time":"20180712","count":32},{"time":"20180713","count":35},{"time":"20180715","count":1},{"time":"20180716","count":25},{"time":"20180717","count":41},{"time":"20180718","count":28},{"time":"20180719","count":31},{"time":"20180720","count":36},{"time":"20180721","count":6},{"time":"20180722","count":4},{"time":"20180723","count":32},{"time":"20180724","count":27},{"time":"20180725","count":38},{"time":"20180726","count":27},{"time":"20180727","count":31},{"time":"20180728","count":1},{"time":"20180729","count":4},{"time":"20180730","count":39},{"time":"20180731","count":45},{"time":"20180801","count":22},{"time":"20180802","count":45},{"time":"20180803","count":37},{"time":"20180804","count":1},{"time":"20180805","count":3},{"time":"20180806","count":56},{"time":"20180807","count":21},{"time":"20180808","count":27},{"time":"20180809","count":24},{"time":"20180810","count":30},{"time":"20180811","count":1},{"time":"20180812","count":2},{"time":"20180813","count":27},{"time":"20180814","count":31},{"time":"20180815","count":19},{"time":"20180816","count":26},{"time":"20180817","count":27},{"time":"20180818","count":2},{"time":"20180819","count":3},{"time":"20180820","count":30},{"time":"20180821","count":17},{"time":"20180822","count":14},{"time":"20180823","count":11},{"time":"20180824","count":43},{"time":"20180827","count":22},{"time":"20180828","count":27},{"time":"20180829","count":28},{"time":"20180830","count":20},{"time":"20180831","count":17},{"time":"20180901","count":4},{"time":"20180902","count":4},{"time":"20180903","count":8},{"time":"20180904","count":33},{"time":"20180905","count":22},{"time":"20180906","count":28},{"time":"20180907","count":42},{"time":"20180908","count":2},{"time":"20180909","count":2},{"time":"20180910","count":22},{"time":"20180911","count":23},{"time":"20180912","count":21},{"time":"20180913","count":50},{"time":"20180914","count":25},{"time":"20180915","count":2},{"time":"20180916","count":4},{"time":"20180917","count":26},{"time":"20180918","count":23},{"time":"20180919","count":15},{"time":"20180920","count":14},{"time":"20180921","count":19},{"time":"20180922","count":2},{"time":"20180924","count":10},{"time":"20180925","count":25},{"time":"20180926","count":25},{"time":"20180927","count":23},{"time":"20180928","count":25},{"time":"20180929","count":1},{"time":"20180930","count":1},{"time":"20181001","count":30},{"time":"20181002","count":12},{"time":"20181003","count":28},{"time":"20181004","count":26},{"time":"20181005","count":39},{"time":"20181006","count":3},{"time":"20181008","count":21},{"time":"20181009","count":24},{"time":"20181010","count":19},{"time":"20181011","count":26},{"time":"20181012","count":27},{"time":"20181015","count":23},{"time":"20181016","count":23},{"time":"20181017","count":34},{"time":"20181018","count":18},{"time":"20181019","count":19},{"time":"20181020","count":1},{"time":"20181021","count":2},{"time":"20181022","count":28},{"time":"20181023","count":23},{"time":"20181024","count":29},{"time":"20181025","count":30},{"time":"20181026","count":26},{"time":"20181028","count":2},{"time":"20181029","count":33},{"time":"20181030","count":31},{"time":"20181031","count":31},{"time":"20181101","count":18},{"time":"20181102","count":24},{"time":"20181103","count":3},{"time":"20181104","count":2},{"time":"20181105","count":33},{"time":"20181106","count":27},{"time":"20181107","count":24},{"time":"20181108","count":28},{"time":"20181109","count":24},{"time":"20181110","count":2},{"time":"20181111","count":1},{"time":"20181112","count":36},{"time":"20181113","count":28},{"time":"20181114","count":25},{"time":"20181115","count":35},{"time":"20181116","count":27},{"time":"20181117","count":5},{"time":"20181118","count":1},{"time":"20181119","count":27},{"time":"20181120","count":35},{"time":"20181121","count":25},{"time":"20181122","count":30},{"time":"20181123","count":28},{"time":"20181124","count":4},{"time":"20181125","count":4},{"time":"20181126","count":35},{"time":"20181127","count":29},{"time":"20181128","count":21},{"time":"20181129","count":40},{"time":"20181130","count":23},{"time":"20181201","count":2},{"time":"20181202","count":2},{"time":"20181203","count":26},{"time":"20181204","count":15},{"time":"20181205","count":23},{"time":"20181206","count":31},{"time":"20181207","count":32},{"time":"20181208","count":2},{"time":"20181209","count":2},{"time":"20181210","count":22},{"time":"20181211","count":26},{"time":"20181212","count":26},{"time":"20181213","count":34},{"time":"20181214","count":22},{"time":"20181215","count":5},{"time":"20181216","count":5},{"time":"20181217","count":35},{"time":"20181218","count":23},{"time":"20181219","count":45},{"time":"20181220","count":37},{"time":"20181221","count":39},{"time":"20181222","count":9},{"time":"20181223","count":2},{"time":"20181224","count":12},{"time":"20181225","count":6},{"time":"20181226","count":28},{"time":"20181227","count":34},{"time":"20181228","count":26},{"time":"20181229","count":3},{"time":"20181230","count":3},{"time":"20181231","count":14},{"time":"20190101","count":4},{"time":"20190102","count":26},{"time":"20190103","count":27},{"time":"20190104","count":12},{"time":"20190106","count":1},{"time":"20190107","count":100},{"time":"20190108","count":65},{"time":"20190109","count":30},{"time":"20190110","count":26},{"time":"20190111","count":36},{"time":"20190112","count":4},{"time":"20190113","count":3},{"time":"20190114","count":30},{"time":"20190115","count":26},{"time":"20190116","count":40},{"time":"20190117","count":37},{"time":"20190118","count":27},{"time":"20190119","count":4},{"time":"20190120","count":4},{"time":"20190121","count":27},{"time":"20190122","count":35},{"time":"20190123","count":26},{"time":"20190124","count":38},{"time":"20190125","count":37},{"time":"20190126","count":28},{"time":"20190127","count":4},{"time":"20190128","count":23},{"time":"20190129","count":39},{"time":"20190130","count":48},{"time":"20190131","count":33},{"time":"20190201","count":39},{"time":"20190202","count":2},{"time":"20190203","count":1},{"time":"20190204","count":41},{"time":"20190205","count":32},{"time":"20190206","count":47},{"time":"20190207","count":66},{"time":"20190208","count":150},{"time":"20190209","count":35},{"time":"20190210","count":34},{"time":"20190211","count":76},{"time":"20190212","count":27},{"time":"20190213","count":37},{"time":"20190214","count":44},{"time":"20190215","count":48},{"time":"20190216","count":2},{"time":"20190217","count":6},{"time":"20190218","count":30},{"time":"20190219","count":52},{"time":"20190220","count":43},{"time":"20190221","count":52},{"time":"20190222","count":37},{"time":"20190223","count":8},{"time":"20190225","count":37},{"time":"20190226","count":48},{"time":"20190227","count":29},{"time":"20190228","count":45},{"time":"20190301","count":45},{"time":"20190302","count":3},{"time":"20190303","count":3},{"time":"20190304","count":39},{"time":"20190305","count":42},{"time":"20190306","count":51},{"time":"20190307","count":40},{"time":"20190308","count":40},{"time":"20190309","count":1},{"time":"20190310","count":3},{"time":"20190311","count":39},{"time":"20190312","count":36},{"time":"20190313","count":32},{"time":"20190314","count":42},{"time":"20190315","count":40},{"time":"20190316","count":20},{"time":"20190317","count":6},{"time":"20190318","count":33},{"time":"20190319","count":39},{"time":"20190320","count":34},{"time":"20190321","count":35},{"time":"20190322","count":36},{"time":"20190323","count":1},{"time":"20190325","count":32},{"time":"20190326","count":32},{"time":"20190327","count":37},{"time":"20190328","count":38},{"time":"20190329","count":29},{"time":"20190330","count":4},{"time":"20190331","count":2},{"time":"20190401","count":28},{"time":"20190402","count":34},{"time":"20190403","count":26},{"time":"20190404","count":27},{"time":"20190405","count":45},{"time":"20190406","count":4},{"time":"20190408","count":30},{"time":"20190409","count":57},{"time":"20190410","count":41},{"time":"20190411","count":30},{"time":"20190412","count":26},{"time":"20190413","count":2},{"time":"20190414","count":2},{"time":"20190415","count":29},{"time":"20190416","count":24},{"time":"20190417","count":50},{"time":"20190418","count":48},{"time":"20190419","count":54},{"time":"20190420","count":5},{"time":"20190422","count":38},{"time":"20190423","count":28},{"time":"20190424","count":48},{"time":"20190425","count":65},{"time":"20190426","count":47},{"time":"20190427","count":3},{"time":"20190428","count":4},{"time":"20190429","count":30},{"time":"20190430","count":46},{"time":"20190501","count":29},{"time":"20190502","count":37},{"time":"20190503","count":44},{"time":"20190504","count":9},{"time":"20190505","count":3},{"time":"20190506","count":53},{"time":"20190507","count":52},{"time":"20190508","count":48},{"time":"20190509","count":44},{"time":"20190510","count":70},{"time":"20190511","count":1},{"time":"20190512","count":4},{"time":"20190513","count":95},{"time":"20190514","count":73},{"time":"20190515","count":34},{"time":"20190516","count":39},{"time":"20190517","count":46},{"time":"20190518","count":13},{"time":"20190520","count":52},{"time":"20190521","count":39},{"time":"20190522","count":31},{"time":"20190523","count":34},{"time":"20190524","count":52},{"time":"20190525","count":4},{"time":"20190526","count":2},{"time":"20190527","count":18},{"time":"20190528","count":36},{"time":"20190529","count":38},{"time":"20190530","count":39},{"time":"20190531","count":33},{"time":"20190601","count":4},{"time":"20190602","count":5},{"time":"20190603","count":26},{"time":"20190604","count":17},{"time":"20190605","count":33},{"time":"20190606","count":36},{"time":"20190607","count":52},{"time":"20190608","count":1},{"time":"20190610","count":48},{"time":"20190611","count":40},{"time":"20190612","count":55},{"time":"20190613","count":37},{"time":"20190614","count":41},{"time":"20190615","count":5},{"time":"20190616","count":1},{"time":"20190617","count":48},{"time":"20190618","count":65},{"time":"20190619","count":51},{"time":"20190620","count":58},{"time":"20190621","count":72},{"time":"20190622","count":2},{"time":"20190624","count":38},{"time":"20190625","count":26},{"time":"20190626","count":30},{"time":"20190627","count":21},{"time":"20190628","count":32},{"time":"20190629","count":1},{"time":"20190630","count":1},{"time":"20190701","count":44},{"time":"20190702","count":45},{"time":"20190703","count":36},{"time":"20190704","count":18},{"time":"20190705","count":41},{"time":"20190706","count":3},{"time":"20190707","count":2},{"time":"20190708","count":36},{"time":"20190709","count":48},{"time":"20190710","count":29},{"time":"20190711","count":27},{"time":"20190712","count":30},{"time":"20190713","count":4},{"time":"20190714","count":2},{"time":"20190715","count":29},{"time":"20190716","count":48},{"time":"20190717","count":42},{"time":"20190718","count":28},{"time":"20190719","count":39},{"time":"20190720","count":9},{"time":"20190722","count":42},{"time":"20190723","count":36},{"time":"20190724","count":35},{"time":"20190725","count":23},{"time":"20190726","count":38},{"time":"20190727","count":3},{"time":"20190728","count":2},{"time":"20190729","count":42},{"time":"20190730","count":36},{"time":"20190731","count":36},{"time":"20190801","count":23},{"time":"20190802","count":45},{"time":"20190803","count":9},{"time":"20190804","count":2},{"time":"20190805","count":31},{"time":"20190806","count":32},{"time":"20190807","count":44},{"time":"20190808","count":38},{"time":"20190809","count":29},{"time":"20190810","count":3},{"time":"20190811","count":2},{"time":"20190812","count":24},{"time":"20190813","count":34},{"time":"20190814","count":28},{"time":"20190815","count":12},{"time":"20190816","count":32},{"time":"20190817","count":5},{"time":"20190819","count":18},{"time":"20190820","count":24},{"time":"20190821","count":36},{"time":"20190822","count":45},{"time":"20190823","count":34},{"time":"20190824","count":2},{"time":"20190825","count":2},{"time":"20190826","count":25},{"time":"20190827","count":33},{"time":"20190828","count":25},{"time":"20190829","count":21},{"time":"20190830","count":28},{"time":"20190831","count":2},{"time":"20190901","count":2},{"time":"20190902","count":6},{"time":"20190903","count":25},{"time":"20190904","count":23},{"time":"20190905","count":33},{"time":"20190906","count":37},{"time":"20190907","count":2},{"time":"20190908","count":1},{"time":"20190909","count":31},{"time":"20190910","count":21},{"time":"20190911","count":31},{"time":"20190912","count":40},{"time":"20190913","count":22},{"time":"20190915","count":2},{"time":"20190916","count":38},{"time":"20190917","count":30},{"time":"20190918","count":20},{"time":"20190919","count":33},{"time":"20190920","count":37},{"time":"20190921","count":7},{"time":"20190922","count":4},{"time":"20190923","count":54},{"time":"20190924","count":52},{"time":"20190925","count":153},{"time":"20190926","count":67},{"time":"20190927","count":43},{"time":"20190928","count":2},{"time":"20190929","count":3},{"time":"20190930","count":34},{"time":"20191001","count":34},{"time":"20191002","count":23},{"time":"20191003","count":98},{"time":"20191004","count":71},{"time":"20191005","count":2},{"time":"20191007","count":32},{"time":"20191008","count":20},{"time":"20191009","count":24},{"time":"20191010","count":23},{"time":"20191011","count":19},{"time":"20191012","count":1},{"time":"20191013","count":7},{"time":"20191014","count":25},{"time":"20191015","count":35},{"time":"20191016","count":34},{"time":"20191017","count":23},{"time":"20191018","count":29},{"time":"20191019","count":5},{"time":"20191020","count":4},{"time":"20191021","count":29},{"time":"20191022","count":24},{"time":"20191023","count":36},{"time":"20191024","count":19},{"time":"20191025","count":25},{"time":"20191026","count":5},{"time":"20191027","count":1},{"time":"20191028","count":14},{"time":"20191029","count":17},{"time":"20191030","count":29},{"time":"20191031","count":60},{"time":"20191101","count":22},{"time":"20191102","count":5},{"time":"20191103","count":1},{"time":"20191104","count":28},{"time":"20191105","count":28},{"time":"20191106","count":34},{"time":"20191107","count":28},{"time":"20191108","count":27},{"time":"20191109","count":1},{"time":"20191110","count":1},{"time":"20191111","count":25},{"time":"20191112","count":24},{"time":"20191113","count":28},{"time":"20191114","count":15},{"time":"20191115","count":21},{"time":"20191116","count":2},{"time":"20191117","count":1},{"time":"20191118","count":31},{"time":"20191119","count":27},{"time":"20191120","count":36},{"time":"20191121","count":23},{"time":"20191122","count":28},{"time":"20191123","count":4},{"time":"20191124","count":5},{"time":"20191125","count":19},{"time":"20191126","count":16},{"time":"20191127","count":30},{"time":"20191128","count":13},{"time":"20191129","count":35},{"time":"20191130","count":2},{"time":"20191201","count":6},{"time":"20191202","count":35},{"time":"20191203","count":37},{"time":"20191204","count":37},{"time":"20191205","count":31},{"time":"20191206","count":33},{"time":"20191207","count":6},{"time":"20191208","count":3},{"time":"20191209","count":20},{"time":"20191210","count":34},{"time":"20191211","count":32},{"time":"20191212","count":35},{"time":"20191213","count":37},{"time":"20191214","count":3},{"time":"20191215","count":1},{"time":"20191216","count":32},{"time":"20191217","count":48},{"time":"20191218","count":42},{"time":"20191219","count":32},{"time":"20191220","count":30},{"time":"20191221","count":4},{"time":"20191222","count":1},{"time":"20191223","count":23},{"time":"20191224","count":24},{"time":"20191225","count":6},{"time":"20191226","count":38},{"time":"20191227","count":32},{"time":"20191228","count":1},{"time":"20191229","count":1},{"time":"20191230","count":29},{"time":"20191231","count":34},{"time":"20200101","count":16},{"time":"20200102","count":25},{"time":"20200103","count":31},{"time":"20200104","count":8},{"time":"20200105","count":3},{"time":"20200106","count":23},{"time":"20200107","count":40},{"time":"20200108","count":18},{"time":"20200109","count":24},{"time":"20200110","count":26},{"time":"20200111","count":6},{"time":"20200112","count":6},{"time":"20200113","count":21},{"time":"20200114","count":19},{"time":"20200115","count":12},{"time":"20200116","count":22},{"time":"20200117","count":29},{"time":"20200118","count":5},{"time":"20200119","count":1},{"time":"20200120","count":16},{"time":"20200121","count":31},{"time":"20200122","count":25},{"time":"20200123","count":38},{"time":"20200124","count":55},{"time":"20200125","count":4},{"time":"20200126","count":4},{"time":"20200127","count":55},{"time":"20200128","count":33},{"time":"20200129","count":38},{"time":"20200130","count":34},{"time":"20200131","count":23},{"time":"20200201","count":4},{"time":"20200202","count":3},{"time":"20200203","count":97},{"time":"20200204","count":118},{"time":"20200205","count":26},{"time":"20200206","count":35},{"time":"20200207","count":30},{"time":"20200208","count":3},{"time":"20200209","count":2},{"time":"20200210","count":30},{"time":"20200211","count":17},{"time":"20200212","count":25},{"time":"20200213","count":25},{"time":"20200214","count":24},{"time":"20200215","count":7},{"time":"20200216","count":1},{"time":"20200217","count":28},{"time":"20200218","count":29},{"time":"20200219","count":40},{"time":"20200220","count":27},{"time":"20200221","count":34},{"time":"20200222","count":3},{"time":"20200223","count":2},{"time":"20200224","count":27},{"time":"20200225","count":27},{"time":"20200226","count":13},{"time":"20200227","count":29},{"time":"20200228","count":33},{"time":"20200229","count":3},{"time":"20200301","count":1},{"time":"20200302","count":27},{"time":"20200303","count":27},{"time":"20200304","count":30},{"time":"20200305","count":22},{"time":"20200306","count":33},{"time":"20200307","count":4},{"time":"20200308","count":1},{"time":"20200309","count":17},{"time":"20200310","count":27},{"time":"20200311","count":20},{"time":"20200312","count":23},{"time":"20200313","count":20},{"time":"20200314","count":1},{"time":"20200315","count":2},{"time":"20200316","count":29},{"time":"20200317","count":22},{"time":"20200318","count":25},{"time":"20200319","count":30},{"time":"20200320","count":26},{"time":"20200321","count":5},{"time":"20200323","count":27},{"time":"20200324","count":40},{"time":"20200325","count":29},{"time":"20200326","count":31},{"time":"20200327","count":19},{"time":"20200328","count":4},{"time":"20200329","count":2},{"time":"20200330","count":35},{"time":"20200331","count":34},{"time":"20200401","count":22},{"time":"20200402","count":20},{"time":"20200403","count":21},{"time":"20200404","count":5},{"time":"20200405","count":2},{"time":"20200406","count":26},{"time":"20200407","count":18},{"time":"20200408","count":24},{"time":"20200409","count":19},{"time":"20200410","count":29},{"time":"20200411","count":3},{"time":"20200412","count":2},{"time":"20200413","count":24},{"time":"20200414","count":27},{"time":"20200415","count":32},{"time":"20200416","count":21},{"time":"20200417","count":30},{"time":"20200418","count":4},{"time":"20200419","count":2},{"time":"20200420","count":50},{"time":"20200421","count":34},{"time":"20200422","count":28},{"time":"20200423","count":52},{"time":"20200424","count":35},{"time":"20200425","count":2},{"time":"20200426","count":4},{"time":"20200427","count":31},{"time":"20200428","count":38},{"time":"20200429","count":33},{"time":"20200430","count":37},{"time":"20200501","count":46},{"time":"20200502","count":4},{"time":"20200503","count":1},{"time":"20200504","count":15},{"time":"20200505","count":25},{"time":"20200506","count":32},{"time":"20200507","count":22},{"time":"20200508","count":20},{"time":"20200509","count":2},{"time":"20200511","count":24},{"time":"20200512","count":25},{"time":"20200513","count":28},{"time":"20200514","count":22},{"time":"20200515","count":23},{"time":"20200516","count":4},{"time":"20200517","count":2},{"time":"20200518","count":33},{"time":"20200519","count":18},{"time":"20200520","count":31},{"time":"20200521","count":44},{"time":"20200522","count":20},{"time":"20200523","count":7},{"time":"20200524","count":2},{"time":"20200525","count":12},{"time":"20200526","count":34},{"time":"20200527","count":18},{"time":"20200528","count":21},{"time":"20200529","count":20},{"time":"20200530","count":3},{"time":"20200531","count":2},{"time":"20200601","count":26},{"time":"20200602","count":27},{"time":"20200603","count":29},{"time":"20200604","count":26},{"time":"20200605","count":14},{"time":"20200606","count":3},{"time":"20200607","count":1},{"time":"20200608","count":12},{"time":"20200609","count":22},{"time":"20200610","count":15},{"time":"20200611","count":18},{"time":"20200612","count":19},{"time":"20200613","count":3},{"time":"20200614","count":1},{"time":"20200615","count":27},{"time":"20200616","count":28},{"time":"20200617","count":31},{"time":"20200618","count":30},{"time":"20200619","count":27},{"time":"20200620","count":4},{"time":"20200622","count":29},{"time":"20200623","count":26},{"time":"20200624","count":28},{"time":"20200625","count":26},{"time":"20200626","count":20},{"time":"20200627","count":7},{"time":"20200628","count":1},{"time":"20200629","count":25},{"time":"20200630","count":20},{"time":"20200701","count":18},{"time":"20200702","count":19},{"time":"20200703","count":27},{"time":"20200704","count":7},{"time":"20200706","count":32},{"time":"20200707","count":25},{"time":"20200708","count":26},{"time":"20200709","count":26},{"time":"20200710","count":21},{"time":"20200712","count":4},{"time":"20200713","count":27},{"time":"20200714","count":15},{"time":"20200715","count":17},{"time":"20200716","count":15},{"time":"20200717","count":33},{"time":"20200718","count":5},{"time":"20200719","count":2},{"time":"20200720","count":28},{"time":"20200721","count":36},{"time":"20200722","count":20},{"time":"20200723","count":35},{"time":"20200724","count":25},{"time":"20200727","count":27},{"time":"20200728","count":20},{"time":"20200729","count":19},{"time":"20200730","count":23},{"time":"20200731","count":19},{"time":"20200801","count":8},{"time":"20200803","count":15},{"time":"20200804","count":20},{"time":"20200805","count":23},{"time":"20200806","count":30},{"time":"20200807","count":15},{"time":"20200808","count":1},{"time":"20200809","count":1},{"time":"20200810","count":15},{"time":"20200811","count":20},{"time":"20200812","count":20},{"time":"20200813","count":15},{"time":"20200814","count":21},{"time":"20200815","count":2},{"time":"20200816","count":7},{"time":"20200817","count":29},{"time":"20200818","count":36},{"time":"20200819","count":19},{"time":"20200820","count":40},{"time":"20200821","count":27},{"time":"20200822","count":1},{"time":"20200823","count":1},{"time":"20200824","count":30},{"time":"20200825","count":29},{"time":"20200826","count":28},{"time":"20200827","count":30},{"time":"20200828","count":36},{"time":"20200829","count":7},{"time":"20200831","count":16},{"time":"20200901","count":28},{"time":"20200902","count":21},{"time":"20200903","count":27},{"time":"20200904","count":19},{"time":"20200905","count":5},{"time":"20200906","count":2},{"time":"20200907","count":16},{"time":"20200908","count":27},{"time":"20200909","count":25},{"time":"20200910","count":34},{"time":"20200911","count":17},{"time":"20200912","count":1},{"time":"20200913","count":1},{"time":"20200914","count":23},{"time":"20200915","count":31},{"time":"20200916","count":25},{"time":"20200917","count":34},{"time":"20200918","count":34},{"time":"20200919","count":5},{"time":"20200920","count":2},{"time":"20200921","count":42},{"time":"20200922","count":102},{"time":"20200923","count":84},{"time":"20200924","count":26},{"time":"20200925","count":20},{"time":"20200926","count":5},{"time":"20200927","count":3},{"time":"20200928","count":21},{"time":"20200929","count":30},{"time":"20200930","count":39},{"time":"20201001","count":28},{"time":"20201002","count":18},{"time":"20201003","count":9},{"time":"20201004","count":2},{"time":"20201005","count":19},{"time":"20201006","count":26},{"time":"20201007","count":28},{"time":"20201008","count":21},{"time":"20201009","count":39},{"time":"20201010","count":3},{"time":"20201011","count":2},{"time":"20201012","count":24},{"time":"20201013","count":27},{"time":"20201014","count":25},{"time":"20201015","count":22},{"time":"20201016","count":23},{"time":"20201017","count":8},{"time":"20201019","count":26},{"time":"20201020","count":27},{"time":"20201021","count":17},{"time":"20201022","count":22},{"time":"20201023","count":13},{"time":"20201024","count":2},{"time":"20201025","count":1},{"time":"20201026","count":26},{"time":"20201027","count":22},{"time":"20201028","count":25},{"time":"20201029","count":15},{"time":"20201030","count":21},{"time":"20201031","count":5},{"time":"20201101","count":2},{"time":"20201102","count":22},{"time":"20201103","count":24},{"time":"20201104","count":20},{"time":"20201105","count":34},{"time":"20201106","count":28},{"time":"20201107","count":8},{"time":"20201109","count":25},{"time":"20201110","count":25},{"time":"20201111","count":17},{"time":"20201112","count":28},{"time":"20201113","count":30},{"time":"20201115","count":3},{"time":"20201116","count":22},{"time":"20201117","count":18},{"time":"20201118","count":21},{"time":"20201119","count":20},{"time":"20201120","count":26},{"time":"20201121","count":5},{"time":"20201122","count":1},{"time":"20201123","count":13},{"time":"20201124","count":24},{"time":"20201125","count":17},{"time":"20201126","count":25},{"time":"20201127","count":17},{"time":"20201128","count":1},{"time":"20201129","count":1},{"time":"20201130","count":16},{"time":"20201201","count":20},{"time":"20201202","count":21},{"time":"20201203","count":14},{"time":"20201204","count":29},{"time":"20201205","count":4},{"time":"20201207","count":24},{"time":"20201208","count":17},{"time":"20201209","count":26},{"time":"20201210","count":23},{"time":"20201211","count":18},{"time":"20201212","count":4},{"time":"20201213","count":2},{"time":"20201214","count":26},{"time":"20201215","count":28},{"time":"20201216","count":33},{"time":"20201217","count":12},{"time":"20201218","count":34},{"time":"20201219","count":1},{"time":"20201220","count":4},{"time":"20201221","count":22},{"time":"20201222","count":25},{"time":"20201223","count":26},{"time":"20201224","count":20},{"time":"20201225","count":11},{"time":"20201226","count":3},{"time":"20201227","count":2},{"time":"20201228","count":19},{"time":"20201229","count":23},{"time":"20201230","count":18},{"time":"20201231","count":21},{"time":"20210101","count":5},{"time":"20210103","count":4},{"time":"20210104","count":35},{"time":"20210105","count":33},{"time":"20210106","count":23},{"time":"20210107","count":23},{"time":"20210108","count":27},{"time":"20210109","count":1},{"time":"20210110","count":2},{"time":"20210111","count":24},{"time":"20210112","count":23},{"time":"20210113","count":20},{"time":"20210114","count":11},{"time":"20210115","count":19},{"time":"20210116","count":5},{"time":"20210117","count":1},{"time":"20210118","count":4},{"time":"20210119","count":28},{"time":"20210120","count":21},{"time":"20210121","count":22},{"time":"20210122","count":35},{"time":"20210123","count":6},{"time":"20210125","count":32},{"time":"20210126","count":15},{"time":"20210127","count":20},{"time":"20210128","count":22},{"time":"20210129","count":25},{"time":"20210130","count":5},{"time":"20210201","count":17},{"time":"20210202","count":27},{"time":"20210203","count":30},{"time":"20210204","count":22},{"time":"20210205","count":18},{"time":"20210206","count":3},{"time":"20210207","count":6},{"time":"20210208","count":21},{"time":"20210209","count":24},{"time":"20210210","count":41},{"time":"20210211","count":26},{"time":"20210212","count":23},{"time":"20210215","count":18},{"time":"20210216","count":31},{"time":"20210217","count":16},{"time":"20210218","count":26},{"time":"20210219","count":25},{"time":"20210220","count":8},{"time":"20210221","count":3},{"time":"20210222","count":27},{"time":"20210223","count":26},{"time":"20210224","count":26},{"time":"20210225","count":16},{"time":"20210226","count":19},{"time":"20210227","count":4},{"time":"20210228","count":6},{"time":"20210301","count":24},{"time":"20210302","count":61},{"time":"20210303","count":43},{"time":"20210304","count":25},{"time":"20210305","count":27},{"time":"20210306","count":7},{"time":"20210307","count":3},{"time":"20210308","count":24},{"time":"20210309","count":33},{"time":"20210310","count":26},{"time":"20210311","count":27},{"time":"20210312","count":33},{"time":"20210313","count":4},{"time":"20210314","count":1},{"time":"20210315","count":32},{"time":"20210316","count":31},{"time":"20210317","count":43},{"time":"20210318","count":29},{"time":"20210319","count":36},{"time":"20210320","count":6},{"time":"20210321","count":1},{"time":"20210322","count":31},{"time":"20210323","count":31},{"time":"20210324","count":25},{"time":"20210325","count":37},{"time":"20210326","count":33},{"time":"20210327","count":6},{"time":"20210328","count":1},{"time":"20210329","count":35},{"time":"20210330","count":28},{"time":"20210331","count":35},{"time":"20210401","count":22},{"time":"20210402","count":23},{"time":"20210403","count":4},{"time":"20210404","count":1},{"time":"20210405","count":23},{"time":"20210406","count":35},{"time":"20210407","count":24},{"time":"20210408","count":30},{"time":"20210409","count":29},{"time":"20210410","count":2},{"time":"20210411","count":3},{"time":"20210412","count":19},{"time":"20210413","count":11},{"time":"20210414","count":23},{"time":"20210415","count":20},{"time":"20210416","count":33},{"time":"20210417","count":8},{"time":"20210418","count":3},{"time":"20210419","count":23},{"time":"20210420","count":20},{"time":"20210421","count":24},{"time":"20210422","count":21},{"time":"20210423","count":25},{"time":"20210424","count":4},{"time":"20210425","count":4},{"time":"20210426","count":25},{"time":"20210427","count":19},{"time":"20210428","count":27},{"time":"20210429","count":24},{"time":"20210430","count":14},{"time":"20210501","count":2},{"time":"20210502","count":1},{"time":"20210503","count":23},{"time":"20210504","count":26},{"time":"20210505","count":21},{"time":"20210506","count":31},{"time":"20210507","count":28},{"time":"20210508","count":4},{"time":"20210509","count":2},{"time":"20210510","count":24},{"time":"20210511","count":25},{"time":"20210512","count":19},{"time":"20210513","count":21},{"time":"20210514","count":25},{"time":"20210515","count":3},{"time":"20210516","count":3},{"time":"20210517","count":21},{"time":"20210518","count":9},{"time":"20210519","count":16},{"time":"20210520","count":22},{"time":"20210521","count":23},{"time":"20210522","count":3},{"time":"20210523","count":1},{"time":"20210524","count":16},{"time":"20210525","count":22},{"time":"20210526","count":26},{"time":"20210527","count":29},{"time":"20210528","count":25},{"time":"20210529","count":2},{"time":"20210530","count":3},{"time":"20210531","count":27},{"time":"20210601","count":18},{"time":"20210602","count":26},{"time":"20210603","count":41},{"time":"20210604","count":57},{"time":"20210605","count":14},{"time":"20210606","count":2},{"time":"20210607","count":20},{"time":"20210608","count":28},{"time":"20210609","count":24},{"time":"20210610","count":16},{"time":"20210611","count":18},{"time":"20210612","count":10},{"time":"20210613","count":1},{"time":"20210614","count":16},{"time":"20210615","count":19},{"time":"20210616","count":30},{"time":"20210617","count":36},{"time":"20210618","count":26},{"time":"20210619","count":4},{"time":"20210621","count":17},{"time":"20210622","count":20},{"time":"20210623","count":21},{"time":"20210624","count":34},{"time":"20210625","count":22},{"time":"20210626","count":3},{"time":"20210627","count":1},{"time":"20210628","count":14},{"time":"20210629","count":12},{"time":"20210630","count":23},{"time":"20210701","count":17},{"time":"20210702","count":28},{"time":"20210703","count":2},{"time":"20210704","count":1},{"time":"20210705","count":14},{"time":"20210706","count":30},{"time":"20210707","count":23},{"time":"20210708","count":33},{"time":"20210709","count":34},{"time":"20210710","count":5},{"time":"20210712","count":19},{"time":"20210713","count":23},{"time":"20210714","count":23},{"time":"20210715","count":23},{"time":"20210716","count":23},{"time":"20210717","count":5},{"time":"20210718","count":5},{"time":"20210719","count":17},{"time":"20210720","count":20},{"time":"20210721","count":19},{"time":"20210722","count":22},{"time":"20210723","count":25},{"time":"20210724","count":2},{"time":"20210725","count":1},{"time":"20210726","count":34},{"time":"20210727","count":24},{"time":"20210728","count":17},{"time":"20210729","count":21},{"time":"20210730","count":30},{"time":"20210731","count":10},{"time":"20210801","count":3},{"time":"20210802","count":30},{"time":"20210803","count":27},{"time":"20210804","count":22},{"time":"20210805","count":20},{"time":"20210806","count":34},{"time":"20210808","count":2},{"time":"20210809","count":32},{"time":"20210810","count":25},{"time":"20210811","count":36},{"time":"20210812","count":29},{"time":"20210813","count":123},{"time":"20210814","count":3},{"time":"20210815","count":1},{"time":"20210816","count":31},{"time":"20210817","count":19},{"time":"20210818","count":20},{"time":"20210819","count":31},{"time":"20210820","count":21},{"time":"20210821","count":7},{"time":"20210822","count":2},{"time":"20210823","count":21},{"time":"20210824","count":45},{"time":"20210825","count":29},{"time":"20210826","count":25},{"time":"20210827","count":27},{"time":"20210828","count":8},{"time":"20210829","count":1},{"time":"20210830","count":20},{"time":"20210831","count":24},{"time":"20210901","count":23},{"time":"20210902","count":17},{"time":"20210903","count":21},{"time":"20210904","count":2},{"time":"20210905","count":1},{"time":"20210906","count":13},{"time":"20210907","count":21},{"time":"20210908","count":20},{"time":"20210909","count":23},{"time":"20210910","count":28},{"time":"20210911","count":8},{"time":"20210912","count":2},{"time":"20210913","count":21},{"time":"20210914","count":16},{"time":"20210915","count":18},{"time":"20210916","count":17},{"time":"20210917","count":19},{"time":"20210918","count":6},{"time":"20210919","count":1},{"time":"20210920","count":41},{"time":"20210921","count":21},{"time":"20210922","count":23},{"time":"20210923","count":16},{"time":"20210924","count":23},{"time":"20210925","count":3},{"time":"20210927","count":20},{"time":"20210928","count":9},{"time":"20210929","count":20},{"time":"20210930","count":28},{"time":"20211001","count":18},{"time":"20211002","count":1},{"time":"20211003","count":4},{"time":"20211004","count":27},{"time":"20211005","count":25},{"time":"20211006","count":14},{"time":"20211007","count":21},{"time":"20211008","count":24},{"time":"20211009","count":1},{"time":"20211011","count":15},{"time":"20211012","count":20},{"time":"20211013","count":12},{"time":"20211014","count":22},{"time":"20211015","count":13},{"time":"20211016","count":4},{"time":"20211017","count":1},{"time":"20211018","count":18},{"time":"20211019","count":30},{"time":"20211020","count":25},{"time":"20211021","count":33},{"time":"20211022","count":26},{"time":"20211024","count":3},{"time":"20211025","count":21},{"time":"20211026","count":20},{"time":"20211027","count":20},{"time":"20211028","count":19},{"time":"20211029","count":33},{"time":"20211030","count":5},{"time":"20211101","count":15},{"time":"20211102","count":20},{"time":"20211103","count":25},{"time":"20211104","count":20},{"time":"20211105","count":15},{"time":"20211106","count":5},{"time":"20211107","count":1},{"time":"20211108","count":19},{"time":"20211109","count":12},{"time":"20211110","count":24},{"time":"20211111","count":16},{"time":"20211112","count":19},{"time":"20211113","count":6},{"time":"20211115","count":22},{"time":"20211116","count":23},{"time":"20211117","count":28},{"time":"20211118","count":17},{"time":"20211119","count":22},{"time":"20211120","count":4},{"time":"20211121","count":2},{"time":"20211122","count":16},{"time":"20211123","count":12},{"time":"20211124","count":20},{"time":"20211125","count":23},{"time":"20211126","count":15},{"time":"20211127","count":2},{"time":"20211128","count":2},{"time":"20211129","count":27},{"time":"20211130","count":25},{"time":"20211201","count":26},{"time":"20211202","count":25},{"time":"20211203","count":29},{"time":"20211204","count":5},{"time":"20211205","count":3},{"time":"20211206","count":23},{"time":"20211207","count":21},{"time":"20211208","count":22},{"time":"20211209","count":19},{"time":"20211210","count":29},{"time":"20211211","count":5},{"time":"20211213","count":24},{"time":"20211214","count":26},{"time":"20211215","count":18},{"time":"20211216","count":30},{"time":"20211217","count":17},{"time":"20211218","count":4},{"time":"20211219","count":1},{"time":"20211220","count":24},{"time":"20211221","count":23},{"time":"20211222","count":23},{"time":"20211223","count":32},{"time":"20211224","count":21},{"time":"20211225","count":6},{"time":"20211226","count":5},{"time":"20211227","count":16},{"time":"20211228","count":19},{"time":"20211229","count":19},{"time":"20211230","count":23},{"time":"20211231","count":22},{"time":"20220101","count":3},{"time":"20220103","count":13},{"time":"20220104","count":23},{"time":"20220105","count":21},{"time":"20220106","count":21},{"time":"20220107","count":19},{"time":"20220108","count":3},{"time":"20220109","count":3},{"time":"20220110","count":25},{"time":"20220111","count":21},{"time":"20220112","count":20},{"time":"20220113","count":13},{"time":"20220114","count":12},{"time":"20220115","count":1},{"time":"20220117","count":14},{"time":"20220118","count":31},{"time":"20220119","count":15},{"time":"20220120","count":14},{"time":"20220121","count":16},{"time":"20220122","count":5},{"time":"20220123","count":7},{"time":"20220124","count":9},{"time":"20220125","count":18},{"time":"20220126","count":5},{"time":"20220127","count":18},{"time":"20220128","count":22},{"time":"20220129","count":4},{"time":"20220131","count":25},{"time":"20220201","count":19},{"time":"20220202","count":13},{"time":"20220203","count":26},{"time":"20220204","count":21},{"time":"20220205","count":4},{"time":"20220206","count":3},{"time":"20220207","count":18},{"time":"20220208","count":23},{"time":"20220209","count":26},{"time":"20220210","count":35},{"time":"20220211","count":36},{"time":"20220212","count":1},{"time":"20220213","count":3},{"time":"20220214","count":23},{"time":"20220215","count":19},{"time":"20220216","count":27},{"time":"20220217","count":28},{"time":"20220218","count":25},{"time":"20220219","count":3},{"time":"20220220","count":6},{"time":"20220221","count":25},{"time":"20220222","count":21},{"time":"20220223","count":24},{"time":"20220224","count":26},{"time":"20220225","count":41},{"time":"20220226","count":1},{"time":"20220227","count":3},{"time":"20220228","count":15},{"time":"20220301","count":18},{"time":"20220302","count":28},{"time":"20220303","count":16},{"time":"20220304","count":23},{"time":"20220305","count":2},{"time":"20220307","count":18},{"time":"20220308","count":20},{"time":"20220309","count":22},{"time":"20220310","count":20},{"time":"20220311","count":24},{"time":"20220312","count":1},{"time":"20220313","count":2},{"time":"20220314","count":20},{"time":"20220315","count":16},{"time":"20220316","count":20},{"time":"20220317","count":15},{"time":"20220318","count":15},{"time":"20220319","count":7},{"time":"20220321","count":8},{"time":"20220322","count":14},{"time":"20220323","count":16},{"time":"20220324","count":24},{"time":"20220325","count":22},{"time":"20220326","count":5},{"time":"20220327","count":2},{"time":"20220328","count":14},{"time":"20220329","count":22},{"time":"20220330","count":15},{"time":"20220331","count":27},{"time":"20220401","count":20},{"time":"20220402","count":2},{"time":"20220403","count":3},{"time":"20220404","count":16},{"time":"20220405","count":21},{"time":"20220406","count":25},{"time":"20220407","count":23},{"time":"20220408","count":27},{"time":"20220409","count":3},{"time":"20220410","count":3},{"time":"20220411","count":13},{"time":"20220412","count":22},{"time":"20220413","count":20},{"time":"20220414","count":19},{"time":"20220415","count":15},{"time":"20220416","count":1},{"time":"20220417","count":1},{"time":"20220418","count":21},{"time":"20220419","count":24},{"time":"20220420","count":21},{"time":"20220421","count":17},{"time":"20220422","count":18},{"time":"20220423","count":2},{"time":"20220424","count":11},{"time":"20220425","count":18},{"time":"20220426","count":24},{"time":"20220427","count":21},{"time":"20220428","count":23},{"time":"20220429","count":21},{"time":"20220430","count":1},{"time":"20220502","count":22},{"time":"20220503","count":20},{"time":"20220504","count":25},{"time":"20220505","count":23},{"time":"20220506","count":22},{"time":"20220507","count":4},{"time":"20220508","count":1},{"time":"20220509","count":28},{"time":"20220510","count":14},{"time":"20220511","count":18},{"time":"20220512","count":34},{"time":"20220513","count":22},{"time":"20220514","count":2},{"time":"20220516","count":23},{"time":"20220517","count":12},{"time":"20220518","count":23},{"time":"20220519","count":22},{"time":"20220520","count":26},{"time":"20220521","count":1},{"time":"20220522","count":3},{"time":"20220523","count":20},{"time":"20220524","count":20},{"time":"20220525","count":20},{"time":"20220526","count":23},{"time":"20220527","count":17},{"time":"20220528","count":4},{"time":"20220530","count":19},{"time":"20220531","count":20},{"time":"20220601","count":18},{"time":"20220602","count":18},{"time":"20220603","count":18},{"time":"20220604","count":2},{"time":"20220605","count":2},{"time":"20220606","count":14},{"time":"20220607","count":13},{"time":"20220608","count":8},{"time":"20220609","count":18},{"time":"20220610","count":8},{"time":"20220611","count":5},{"time":"20220613","count":12},{"time":"20220614","count":18},{"time":"20220615","count":9},{"time":"20220616","count":13},{"time":"20220617","count":13},{"time":"20220618","count":3},{"time":"20220619","count":3},{"time":"20220620","count":30},{"time":"20220621","count":23},{"time":"20220622","count":20},{"time":"20220623","count":15},{"time":"20220624","count":26},{"time":"20220625","count":2},{"time":"20220626","count":1},{"time":"20220627","count":20},{"time":"20220628","count":31},{"time":"20220629","count":22},{"time":"20220630","count":18},{"time":"20220701","count":15},{"time":"20220702","count":4},{"time":"20220703","count":2},{"time":"20220704","count":10},{"time":"20220705","count":14},{"time":"20220706","count":18},{"time":"20220707","count":21},{"time":"20220708","count":18},{"time":"20220709","count":5},{"time":"20220710","count":2},{"time":"20220711","count":26},{"time":"20220712","count":15},{"time":"20220713","count":27},{"time":"20220714","count":20},{"time":"20220715","count":22},{"time":"20220716","count":3},{"time":"20220717","count":2},{"time":"20220718","count":18},{"time":"20220719","count":11},{"time":"20220720","count":7},{"time":"20220721","count":24},{"time":"20220722","count":17},{"time":"20220723","count":2},{"time":"20220724","count":2},{"time":"20220725","count":11},{"time":"20220726","count":24},{"time":"20220727","count":17},{"time":"20220728","count":15},{"time":"20220729","count":23},{"time":"20220730","count":7},{"time":"20220731","count":1},{"time":"20220801","count":28},{"time":"20220802","count":17},{"time":"20220803","count":19},{"time":"20220804","count":26},{"time":"20220805","count":19},{"time":"20220806","count":7},{"time":"20220808","count":14},{"time":"20220809","count":14},{"time":"20220810","count":17},{"time":"20220811","count":15},{"time":"20220812","count":13},{"time":"20220813","count":3},{"time":"20220814","count":1},{"time":"20220815","count":12},{"time":"20220816","count":13},{"time":"20220817","count":18},{"time":"20220818","count":23},{"time":"20220819","count":15},{"time":"20220821","count":4},{"time":"20220822","count":13},{"time":"20220823","count":25},{"time":"20220824","count":18},{"time":"20220825","count":15},{"time":"20220826","count":23},{"time":"20220827","count":3},{"time":"20220828","count":8},{"time":"20220829","count":18},{"time":"20220830","count":28},{"time":"20220831","count":22},{"time":"20220901","count":28},{"time":"20220902","count":16},{"time":"20220903","count":6},{"time":"20220904","count":1},{"time":"20220905","count":9},{"time":"20220906","count":20},{"time":"20220907","count":25},{"time":"20220908","count":28},{"time":"20220909","count":43},{"time":"20220910","count":4},{"time":"20220911","count":3},{"time":"20220912","count":21},{"time":"20220913","count":24},{"time":"20220914","count":16},{"time":"20220915","count":17},{"time":"20220916","count":21},{"time":"20220917","count":3},{"time":"20220918","count":1},{"time":"20220919","count":19},{"time":"20220920","count":23},{"time":"20220921","count":14},{"time":"20220922","count":12},{"time":"20220923","count":14},{"time":"20220924","count":3},{"time":"20220925","count":1},{"time":"20220926","count":29},{"time":"20220927","count":22},{"time":"20220928","count":16},{"time":"20220929","count":14},{"time":"20220930","count":20},{"time":"20221001","count":8},{"time":"20221002","count":4},{"time":"20221003","count":11},{"time":"20221004","count":20},{"time":"20221005","count":13},{"time":"20221006","count":16},{"time":"20221007","count":18},{"time":"20221008","count":5},{"time":"20221009","count":3},{"time":"20221010","count":29},{"time":"20221011","count":20},{"time":"20221012","count":25},{"time":"20221013","count":28},{"time":"20221014","count":29},{"time":"20221015","count":2},{"time":"20221016","count":2},{"time":"20221017","count":23},{"time":"20221018","count":22},{"time":"20221019","count":17},{"time":"20221020","count":23},{"time":"20221021","count":18},{"time":"20221022","count":8},{"time":"20221023","count":2},{"time":"20221024","count":10},{"time":"20221025","count":11},{"time":"20221026","count":7},{"time":"20221027","count":10},{"time":"20221028","count":14},{"time":"20221029","count":8},{"time":"20221030","count":1},{"time":"20221031","count":21},{"time":"20221101","count":21},{"time":"20221102","count":14},{"time":"20221103","count":31},{"time":"20221104","count":12},{"time":"20221105","count":4},{"time":"20221106","count":2},{"time":"20221107","count":15},{"time":"20221108","count":16},{"time":"20221109","count":26},{"time":"20221110","count":20},{"time":"20221111","count":24},{"time":"20221112","count":2},{"time":"20221114","count":21},{"time":"20221115","count":15},{"time":"20221116","count":19},{"time":"20221117","count":30},{"time":"20221118","count":23},{"time":"20221119","count":2},{"time":"20221120","count":3},{"time":"20221121","count":18},{"time":"20221122","count":19},{"time":"20221123","count":12},{"time":"20221124","count":8},{"time":"20221125","count":20},{"time":"20221126","count":5},{"time":"20221127","count":6},{"time":"20221128","count":15},{"time":"20221129","count":25},{"time":"20221130","count":12},{"time":"20221201","count":25},{"time":"20221202","count":17},{"time":"20221203","count":2},{"time":"20221204","count":1},{"time":"20221205","count":10},{"time":"20221206","count":19},{"time":"20221207","count":15},{"time":"20221208","count":24},{"time":"20221209","count":16},{"time":"20221210","count":5},{"time":"20221212","count":25},{"time":"20221213","count":20},{"time":"20221214","count":11},{"time":"20221215","count":21},{"time":"20221216","count":15},{"time":"20221217","count":4},{"time":"20221218","count":4},{"time":"20221219","count":18},{"time":"20221220","count":16},{"time":"20221221","count":16},{"time":"20221222","count":14},{"time":"20221223","count":21},{"time":"20221224","count":3},{"time":"20221225","count":5},{"time":"20221226","count":10},{"time":"20221227","count":21},{"time":"20221228","count":20},{"time":"20221229","count":16},{"time":"20221230","count":33},{"time":"20221231","count":5},{"time":"20230101","count":1},{"time":"20230102","count":11},{"time":"20230103","count":15},{"time":"20230104","count":17},{"time":"20230105","count":23},{"time":"20230106","count":18},{"time":"20230107","count":1},{"time":"20230108","count":1},{"time":"20230109","count":13},{"time":"20230110","count":16},{"time":"20230111","count":20},{"time":"20230112","count":12},{"time":"20230113","count":27},{"time":"20230114","count":2},{"time":"20230115","count":1},{"time":"20230116","count":14},{"time":"20230117","count":21},{"time":"20230118","count":25},{"time":"20230119","count":19},{"time":"20230120","count":29},{"time":"20230121","count":3},{"time":"20230122","count":3},{"time":"20230123","count":24},{"time":"20230124","count":25},{"time":"20230125","count":24},{"time":"20230126","count":19},{"time":"20230127","count":18},{"time":"20230128","count":6},{"time":"20230129","count":1},{"time":"20230130","count":19},{"time":"20230131","count":17},{"time":"20230201","count":14},{"time":"20230202","count":23},{"time":"20230203","count":23},{"time":"20230204","count":8},{"time":"20230205","count":6},{"time":"20230206","count":37},{"time":"20230207","count":20},{"time":"20230208","count":19},{"time":"20230209","count":29},{"time":"20230210","count":21},{"time":"20230211","count":5},{"time":"20230212","count":1},{"time":"20230213","count":33},{"time":"20230214","count":28},{"time":"20230215","count":24},{"time":"20230216","count":32},{"time":"20230217","count":29},{"time":"20230218","count":5},{"time":"20230219","count":2},{"time":"20230220","count":23},{"time":"20230221","count":20},{"time":"20230222","count":28},{"time":"20230223","count":33},{"time":"20230224","count":19},{"time":"20230225","count":4},{"time":"20230227","count":26},{"time":"20230228","count":18},{"time":"20230301","count":22},{"time":"20230302","count":22},{"time":"20230303","count":23},{"time":"20230304","count":8},{"time":"20230305","count":2},{"time":"20230306","count":22},{"time":"20230307","count":31},{"time":"20230308","count":23},{"time":"20230309","count":21},{"time":"20230310","count":29},{"time":"20230311","count":1},{"time":"20230312","count":2},{"time":"20230313","count":19},{"time":"20230314","count":21},{"time":"20230315","count":6},{"time":"20230316","count":21},{"time":"20230317","count":24},{"time":"20230318","count":3},{"time":"20230319","count":2},{"time":"20230320","count":19},{"time":"20230321","count":16},{"time":"20230322","count":13},{"time":"20230323","count":13},{"time":"20230324","count":28},{"time":"20230326","count":1},{"time":"20230327","count":18},{"time":"20230328","count":19},{"time":"20230329","count":22},{"time":"20230330","count":10},{"time":"20230331","count":19},{"time":"20230401","count":7},{"time":"20230402","count":1},{"time":"20230403","count":19},{"time":"20230404","count":22},{"time":"20230405","count":23},{"time":"20230406","count":18},{"time":"20230407","count":10},{"time":"20230408","count":4},{"time":"20230410","count":23},{"time":"20230411","count":18},{"time":"20230412","count":20},{"time":"20230413","count":19},{"time":"20230414","count":13},{"time":"20230415","count":5},{"time":"20230416","count":6},{"time":"20230417","count":17},{"time":"20230418","count":15},{"time":"20230419","count":15},{"time":"20230420","count":25},{"time":"20230421","count":14},{"time":"20230422","count":1},{"time":"20230424","count":42},{"time":"20230425","count":25},{"time":"20230426","count":14},{"time":"20230427","count":31},{"time":"20230428","count":16},{"time":"20230429","count":1},{"time":"20230430","count":4},{"time":"20230501","count":8},{"time":"20230502","count":20},{"time":"20230503","count":28},{"time":"20230504","count":25},{"time":"20230505","count":27},{"time":"20230506","count":5},{"time":"20230507","count":2},{"time":"20230508","count":20},{"time":"20230509","count":19},{"time":"20230510","count":14},{"time":"20230511","count":21},{"time":"20230512","count":23},{"time":"20230513","count":6},{"time":"20230514","count":1},{"time":"20230515","count":22},{"time":"20230516","count":16},{"time":"20230517","count":17},{"time":"20230518","count":30},{"time":"20230519","count":23},{"time":"20230520","count":3},{"time":"20230521","count":1},{"time":"20230522","count":24},{"time":"20230523","count":25},{"time":"20230524","count":14},{"time":"20230525","count":9},{"time":"20230526","count":13},{"time":"20230527","count":4},{"time":"20230528","count":3},{"time":"20230529","count":19},{"time":"20230530","count":13},{"time":"20230531","count":16},{"time":"20230601","count":15},{"time":"20230602","count":22},{"time":"20230603","count":4},{"time":"20230604","count":6},{"time":"20230605","count":14},{"time":"20230606","count":21},{"time":"20230607","count":25},{"time":"20230608","count":17},{"time":"20230609","count":13},{"time":"20230610","count":6},{"time":"20230611","count":3},{"time":"20230612","count":31},{"time":"20230613","count":23},{"time":"20230614","count":19},{"time":"20230615","count":25},{"time":"20230616","count":14},{"time":"20230617","count":9},{"time":"20230619","count":18},{"time":"20230620","count":26},{"time":"20230621","count":17},{"time":"20230622","count":19},{"time":"20230623","count":26},{"time":"20230626","count":24},{"time":"20230627","count":19},{"time":"20230628","count":21},{"time":"20230629","count":12},{"time":"20230630","count":26},{"time":"20230701","count":3},{"time":"20230702","count":1},{"time":"20230703","count":53},{"time":"20230704","count":15},{"time":"20230705","count":13},{"time":"20230706","count":24},{"time":"20230707","count":15},{"time":"20230708","count":4},{"time":"20230709","count":3},{"time":"20230710","count":12},{"time":"20230711","count":14},{"time":"20230712","count":14},{"time":"20230713","count":19},{"time":"20230714","count":26},{"time":"20230715","count":1},{"time":"20230716","count":3},{"time":"20230717","count":22},{"time":"20230718","count":26},{"time":"20230719","count":24},{"time":"20230720","count":15},{"time":"20230721","count":21},{"time":"20230722","count":8},{"time":"20230723","count":4},{"time":"20230724","count":16},{"time":"20230725","count":35},{"time":"20230726","count":22},{"time":"20230727","count":18},{"time":"20230728","count":23},{"time":"20230730","count":1},{"time":"20230731","count":37},{"time":"20230801","count":24},{"time":"20230802","count":13},{"time":"20230803","count":14},{"time":"20230804","count":13},{"time":"20230805","count":3},{"time":"20230806","count":7},{"time":"20230807","count":20},{"time":"20230808","count":14},{"time":"20230809","count":23},{"time":"20230810","count":22},{"time":"20230811","count":23},{"time":"20230812","count":6},{"time":"20230813","count":1},{"time":"20230814","count":26},{"time":"20230815","count":9},{"time":"20230816","count":28},{"time":"20230817","count":23},{"time":"20230818","count":15},{"time":"20230819","count":5},{"time":"20230820","count":3},{"time":"20230821","count":17},{"time":"20230822","count":28},{"time":"20230823","count":17},{"time":"20230824","count":23},{"time":"20230825","count":29},{"time":"20230826","count":5},{"time":"20230827","count":5},{"time":"20230828","count":28},{"time":"20230829","count":10},{"time":"20230830","count":14},{"time":"20230831","count":28},{"time":"20230901","count":11},{"time":"20230902","count":10},{"time":"20230903","count":4},{"time":"20230904","count":9},{"time":"20230905","count":23},{"time":"20230906","count":23},{"time":"20230907","count":13},{"time":"20230908","count":35},{"time":"20230909","count":1},{"time":"20230910","count":3},{"time":"20230911","count":16},{"time":"20230912","count":23},{"time":"20230913","count":19},{"time":"20230914","count":15},{"time":"20230915","count":22},{"time":"20230916","count":2},{"time":"20230917","count":1},{"time":"20230918","count":15},{"time":"20230919","count":10},{"time":"20230920","count":10},{"time":"20230921","count":16},{"time":"20230922","count":18},{"time":"20230923","count":3},{"time":"20230925","count":26},{"time":"20230926","count":16},{"time":"20230927","count":16},{"time":"20230928","count":26},{"time":"20230929","count":16},{"time":"20230930","count":10},{"time":"20231001","count":2},{"time":"20231002","count":10},{"time":"20231003","count":18},{"time":"20231004","count":24},{"time":"20231005","count":18},{"time":"20231006","count":31},{"time":"20231007","count":4},{"time":"20231008","count":1},{"time":"20231009","count":11},{"time":"20231010","count":18},{"time":"20231011","count":34},{"time":"20231012","count":32},{"time":"20231013","count":26},{"time":"20231014","count":1},{"time":"20231015","count":1},{"time":"20231016","count":23},{"time":"20231017","count":23},{"time":"20231018","count":17},{"time":"20231019","count":21},{"time":"20231020","count":21},{"time":"20231021","count":11},{"time":"20231022","count":1},{"time":"20231023","count":14},{"time":"20231024","count":10},{"time":"20231025","count":17},{"time":"20231026","count":20},{"time":"20231027","count":21},{"time":"20231028","count":11},{"time":"20231029","count":2},{"time":"20231030","count":33},{"time":"20231031","count":30},{"time":"20231101","count":17},{"time":"20231102","count":18},{"time":"20231103","count":25},{"time":"20231104","count":5},{"time":"20231105","count":2},{"time":"20231106","count":15},{"time":"20231107","count":18},{"time":"20231108","count":14},{"time":"20231109","count":12},{"time":"20231110","count":19},{"time":"20231111","count":7},{"time":"20231112","count":2},{"time":"20231113","count":16},{"time":"20231114","count":9},{"time":"20231115","count":13},{"time":"20231116","count":19},{"time":"20231117","count":23},{"time":"20231118","count":4},{"time":"20231120","count":20},{"time":"20231121","count":23},{"time":"20231122","count":22},{"time":"20231123","count":19},{"time":"20231124","count":15},{"time":"20231125","count":1},{"time":"20231126","count":2},{"time":"20231127","count":23},{"time":"20231128","count":30},{"time":"20231129","count":25},{"time":"20231130","count":23},{"time":"20231201","count":23},{"time":"20231202","count":4},{"time":"20231203","count":4},{"time":"20231204","count":36},{"time":"20231205","count":17},{"time":"20231206","count":18},{"time":"20231207","count":19},{"time":"20231208","count":20},{"time":"20231209","count":2},{"time":"20231210","count":10},{"time":"20231211","count":9},{"time":"20231212","count":20},{"time":"20231213","count":25},{"time":"20231214","count":29},{"time":"20231215","count":27},{"time":"20231216","count":2},{"time":"20231217","count":1},{"time":"20231218","count":27},{"time":"20231219","count":22},{"time":"20231220","count":23},{"time":"20231221","count":14},{"time":"20231222","count":28},{"time":"20231223","count":1},{"time":"20231224","count":3},{"time":"20231225","count":6},{"time":"20231226","count":19},{"time":"20231227","count":15},{"time":"20231228","count":21},{"time":"20231229","count":12},{"time":"20231230","count":3},{"time":"20231231","count":3},{"time":"20240101","count":10},{"time":"20240102","count":14},{"time":"20240103","count":13},{"time":"20240104","count":17},{"time":"20240105","count":22},{"time":"20240106","count":9},{"time":"20240108","count":26},{"time":"20240109","count":15},{"time":"20240110","count":30},{"time":"20240111","count":20},{"time":"20240112","count":13},{"time":"20240114","count":1},{"time":"20240115","count":12},{"time":"20240116","count":15},{"time":"20240117","count":20},{"time":"20240118","count":35},{"time":"20240119","count":19},{"time":"20240120","count":3},{"time":"20240121","count":3},{"time":"20240122","count":27},{"time":"20240123","count":19},{"time":"20240124","count":16},{"time":"20240125","count":19},{"time":"20240126","count":8},{"time":"20240127","count":3},{"time":"20240128","count":3},{"time":"20240129","count":10},{"time":"20240130","count":29},{"time":"20240131","count":21},{"time":"20240201","count":23},{"time":"20240202","count":17},{"time":"20240203","count":5},{"time":"20240204","count":5},{"time":"20240205","count":28},{"time":"20240206","count":17},{"time":"20240207","count":21},{"time":"20240208","count":19},{"time":"20240209","count":17},{"time":"20240210","count":2},{"time":"20240211","count":5},{"time":"20240212","count":21},{"time":"20240213","count":18},{"time":"20240214","count":19},{"time":"20240215","count":21},{"time":"20240216","count":13},{"time":"20240217","count":6},{"time":"20240218","count":4},{"time":"20240219","count":31},{"time":"20240220","count":23},{"time":"20240221","count":26},{"time":"20240222","count":19},{"time":"20240223","count":30},{"time":"20240224","count":1},{"time":"20240226","count":19},{"time":"20240227","count":13},{"time":"20240228","count":18},{"time":"20240229","count":20},{"time":"20240301","count":23},{"time":"20240302","count":4},{"time":"20240303","count":1},{"time":"20240304","count":9},{"time":"20240305","count":18},{"time":"20240306","count":14},{"time":"20240307","count":25},{"time":"20240308","count":19},{"time":"20240310","count":2},{"time":"20240311","count":22},{"time":"20240312","count":19},{"time":"20240313","count":16},{"time":"20240314","count":21},{"time":"20240315","count":23},{"time":"20240316","count":4},{"time":"20240317","count":1},{"time":"20240318","count":20},{"time":"20240319","count":24},{"time":"20240320","count":22},{"time":"20240321","count":20},{"time":"20240322","count":15},{"time":"20240323","count":6},{"time":"20240324","count":3},{"time":"20240325","count":10},{"time":"20240326","count":23},{"time":"20240327","count":31},{"time":"20240328","count":21},{"time":"20240329","count":28},{"time":"20240330","count":2},{"time":"20240401","count":19},{"time":"20240402","count":18},{"time":"20240403","count":20},{"time":"20240404","count":17},{"time":"20240405","count":16},{"time":"20240406","count":5},{"time":"20240408","count":16},{"time":"20240409","count":22},{"time":"20240410","count":21},{"time":"20240411","count":14},{"time":"20240412","count":27},{"time":"20240413","count":6},{"time":"20240414","count":2},{"time":"20240415","count":16},{"time":"20240416","count":19},{"time":"20240417","count":29},{"time":"20240418","count":29},{"time":"20240419","count":33},{"time":"20240420","count":4},{"time":"20240421","count":2},{"time":"20240422","count":17},{"time":"20240423","count":35},{"time":"20240424","count":21},{"time":"20240425","count":29},{"time":"20240426","count":44},{"time":"20240427","count":13},{"time":"20240429","count":35},{"time":"20240430","count":19},{"time":"20240501","count":16},{"time":"20240502","count":21},{"time":"20240503","count":23},{"time":"20240504","count":8},{"time":"20240506","count":28},{"time":"20240507","count":12},{"time":"20240508","count":17},{"time":"20240509","count":20},{"time":"20240510","count":16},{"time":"20240511","count":3},{"time":"20240512","count":2},{"time":"20240513","count":16},{"time":"20240514","count":22},{"time":"20240515","count":14},{"time":"20240516","count":21},{"time":"20240517","count":17},{"time":"20240518","count":1},{"time":"20240519","count":1},{"time":"20240520","count":10},{"time":"20240521","count":26},{"time":"20240522","count":19},{"time":"20240523","count":8},{"time":"20240524","count":15},{"time":"20240526","count":1},{"time":"20240527","count":9},{"time":"20240528","count":22},{"time":"20240529","count":19},{"time":"20240530","count":14},{"time":"20240531","count":20},{"time":"20240601","count":4},{"time":"20240603","count":19},{"time":"20240604","count":16},{"time":"20240605","count":12},{"time":"20240606","count":26},{"time":"20240607","count":28},{"time":"20240608","count":4},{"time":"20240609","count":1},{"time":"20240610","count":12},{"time":"20240611","count":9},{"time":"20240612","count":12},{"time":"20240613","count":12},{"time":"20240614","count":16},{"time":"20240615","count":3},{"time":"20240617","count":36},{"time":"20240618","count":15},{"time":"20240619","count":20},{"time":"20240620","count":26},{"time":"20240621","count":17},{"time":"20240623","count":2},{"time":"20240624","count":19},{"time":"20240625","count":19},{"time":"20240626","count":19},{"time":"20240627","count":36},{"time":"20240628","count":28},{"time":"20240629","count":3},{"time":"20240630","count":1},{"time":"20240701","count":10},{"time":"20240702","count":18},{"time":"20240703","count":29},{"time":"20240704","count":13},{"time":"20240705","count":6},{"time":"20240706","count":4},{"time":"20240707","count":2},{"time":"20240708","count":16},{"time":"20240709","count":20},{"time":"20240710","count":26},{"time":"20240711","count":12},{"time":"20240712","count":24},{"time":"20240714","count":1},{"time":"20240715","count":17},{"time":"20240716","count":21},{"time":"20240717","count":23},{"time":"20240718","count":15},{"time":"20240719","count":4},{"time":"20240720","count":15},{"time":"20240721","count":6},{"time":"20240722","count":20},{"time":"20240723","count":17},{"time":"20240724","count":30},{"time":"20240725","count":11},{"time":"20240726","count":14},{"time":"20240727","count":1},{"time":"20240728","count":1},{"time":"20240729","count":16},{"time":"20240730","count":14},{"time":"20240731","count":7},{"time":"20240801","count":21},{"time":"20240802","count":16},{"time":"20240803","count":7},{"time":"20240805","count":15},{"time":"20240806","count":28},{"time":"20240807","count":18},{"time":"20240808","count":20},{"time":"20240809","count":23},{"time":"20240810","count":3},{"time":"20240811","count":3},{"time":"20240812","count":17},{"time":"20240813","count":51},{"time":"20240814","count":25},{"time":"20240815","count":10},{"time":"20240816","count":21},{"time":"20240817","count":1},{"time":"20240818","count":2},{"time":"20240819","count":15},{"time":"20240820","count":19},{"time":"20240821","count":20},{"time":"20240822","count":14},{"time":"20240823","count":21},{"time":"20240824","count":3},{"time":"20240825","count":4},{"time":"20240826","count":11},{"time":"20240827","count":11},{"time":"20240828","count":10},{"time":"20240829","count":18},{"time":"20240830","count":18},{"time":"20240831","count":4},{"time":"20240902","count":10},{"time":"20240903","count":27},{"time":"20240904","count":9},{"time":"20240905","count":16},{"time":"20240906","count":43},{"time":"20240907","count":3},{"time":"20240908","count":4},{"time":"20240909","count":20},{"time":"20240910","count":17},{"time":"20240911","count":13},{"time":"20240912","count":13},{"time":"20240913","count":17},{"time":"20240914","count":2},{"time":"20240915","count":3},{"time":"20240916","count":4},{"time":"20240917","count":24},{"time":"20240918","count":23},{"time":"20240919","count":36},{"time":"20240920","count":21},{"time":"20240921","count":8},{"time":"20240922","count":1},{"time":"20240923","count":23},{"time":"20240924","count":16},{"time":"20240925","count":15},{"time":"20240926","count":16},{"time":"20240927","count":15},{"time":"20240928","count":5},{"time":"20240930","count":14},{"time":"20241001","count":28},{"time":"20241002","count":9},{"time":"20241003","count":22},{"time":"20241004","count":13},{"time":"20241005","count":1},{"time":"20241007","count":18},{"time":"20241008","count":12},{"time":"20241009","count":17},{"time":"20241010","count":21},{"time":"20241011","count":16},{"time":"20241012","count":2},{"time":"20241014","count":15},{"time":"20241015","count":29},{"time":"20241016","count":30},{"time":"20241017","count":32},{"time":"20241018","count":39},{"time":"20241019","count":4},{"time":"20241020","count":5},{"time":"20241021","count":14},{"time":"20241022","count":36},{"time":"20241023","count":31},{"time":"20241024","count":24},{"time":"20241025","count":18},{"time":"20241026","count":4},{"time":"20241027","count":1},{"time":"20241028","count":14},{"time":"20241029","count":20},{"time":"20241030","count":23},{"time":"20241031","count":10},{"time":"20241101","count":19},{"time":"20241102","count":1},{"time":"20241103","count":1},{"time":"20241104","count":13},{"time":"20241105","count":23},{"time":"20241106","count":14},{"time":"20241107","count":14},{"time":"20241108","count":23},{"time":"20241109","count":9},{"time":"20241110","count":6},{"time":"20241111","count":11},{"time":"20241112","count":15},{"time":"20241113","count":20},{"time":"20241114","count":19},{"time":"20241115","count":16},{"time":"20241116","count":5},{"time":"20241117","count":4},{"time":"20241118","count":13},{"time":"20241119","count":17},{"time":"20241120","count":16},{"time":"20241121","count":17},{"time":"20241122","count":21},{"time":"20241123","count":3},{"time":"20241124","count":3},{"time":"20241125","count":18},{"time":"20241126","count":29},{"time":"20241127","count":20},{"time":"20241128","count":25},{"time":"20241129","count":18},{"time":"20241130","count":2},{"time":"20241201","count":1},{"time":"20241202","count":26},{"time":"20241203","count":24},{"time":"20241204","count":32},{"time":"20241205","count":20},{"time":"20241206","count":34},{"time":"20241207","count":2},{"time":"20241208","count":2},{"time":"20241209","count":17},{"time":"20241210","count":11},{"time":"20241211","count":16},{"time":"20241212","count":20},{"time":"20241213","count":19},{"time":"20241214","count":2},{"time":"20241215","count":4},{"time":"20241216","count":11},{"time":"20241217","count":21},{"time":"20241218","count":9},{"time":"20241219","count":24},{"time":"20241220","count":19},{"time":"20241221","count":4},{"time":"20241222","count":1},{"time":"20241223","count":14},{"time":"20241224","count":10},{"time":"20241225","count":2},{"time":"20241226","count":23},{"time":"20241227","count":19},{"time":"20241228","count":6},{"time":"20241230","count":14},{"time":"20241231","count":14},{"time":"20250101","count":3},{"time":"20250102","count":14},{"time":"20250103","count":24},{"time":"20250104","count":2},{"time":"20250105","count":3},{"time":"20250106","count":7},{"time":"20250107","count":12},{"time":"20250108","count":13},{"time":"20250109","count":13},{"time":"20250110","count":8},{"time":"20250111","count":4},{"time":"20250112","count":2},{"time":"20250113","count":6},{"time":"20250114","count":7},{"time":"20250115","count":13},{"time":"20250116","count":22},{"time":"20250117","count":9},{"time":"20250118","count":1},{"time":"20250119","count":2},{"time":"20250120","count":16},{"time":"20250121","count":12},{"time":"20250122","count":14},{"time":"20250123","count":25},{"time":"20250124","count":14},{"time":"20250126","count":1},{"time":"20250127","count":15},{"time":"20250128","count":26},{"time":"20250129","count":13},{"time":"20250130","count":14},{"time":"20250131","count":15},{"time":"20250201","count":6},{"time":"20250202","count":4},{"time":"20250203","count":18},{"time":"20250204","count":33},{"time":"20250205","count":16},{"time":"20250206","count":20},{"time":"20250207","count":10},{"time":"20250209","count":1},{"time":"20250210","count":20},{"time":"20250211","count":16},{"time":"20250212","count":25},{"time":"20250213","count":17},{"time":"20250214","count":20},{"time":"20250215","count":1},{"time":"20250216","count":2},{"time":"20250217","count":17},{"time":"20250218","count":14},{"time":"20250219","count":25},{"time":"20250220","count":16},{"time":"20250221","count":30},{"time":"20250222","count":2},{"time":"20250223","count":2},{"time":"20250224","count":18},{"time":"20250225","count":15},{"time":"20250226","count":18},{"time":"20250227","count":15},{"time":"20250228","count":15},{"time":"20250301","count":9},{"time":"20250302","count":5},{"time":"20250303","count":15},{"time":"20250304","count":14},{"time":"20250305","count":20},{"time":"20250306","count":18},{"time":"20250307","count":10},{"time":"20250308","count":2},{"time":"20250309","count":2},{"time":"20250310","count":20},{"time":"20250311","count":17},{"time":"20250312","count":14},{"time":"20250313","count":16},{"time":"20250314","count":10},{"time":"20250315","count":1},{"time":"20250316","count":2},{"time":"20250317","count":14},{"time":"20250318","count":20},{"time":"20250319","count":19},{"time":"20250320","count":11},{"time":"20250321","count":13},{"time":"20250322","count":6},{"time":"20250323","count":1},{"time":"20250324","count":15},{"time":"20250325","count":13},{"time":"20250326","count":21},{"time":"20250327","count":17},{"time":"20250328","count":15},{"time":"20250329","count":1},{"time":"20250330","count":2},{"time":"20250331","count":13},{"time":"20250401","count":14},{"time":"20250402","count":21},{"time":"20250403","count":16},{"time":"20250404","count":15},{"time":"20250405","count":1},{"time":"20250406","count":1},{"time":"20250407","count":15},{"time":"20250408","count":17},{"time":"20250409","count":18},{"time":"20250410","count":21},{"time":"20250411","count":19},{"time":"20250414","count":8},{"time":"20250415","count":17},{"time":"20250416","count":10},{"time":"20250417","count":16},{"time":"20250418","count":21},{"time":"20250419","count":2},{"time":"20250421","count":17},{"time":"20250422","count":22},{"time":"20250423","count":13},{"time":"20250424","count":15},{"time":"20250425","count":17},{"time":"20250426","count":5},{"time":"20250428","count":25},{"time":"20250429","count":40},{"time":"20250430","count":18},{"time":"20250501","count":11},{"time":"20250502","count":20},{"time":"20250503","count":2},{"time":"20250504","count":1},{"time":"20250505","count":19},{"time":"20250506","count":15},{"time":"20250507","count":17},{"time":"20250508","count":18},{"time":"20250509","count":29},{"time":"20250510","count":4},{"time":"20250511","count":3},{"time":"20250512","count":13},{"time":"20250513","count":14},{"time":"20250514","count":15},{"time":"20250515","count":13},{"time":"20250516","count":13},{"time":"20250517","count":4},{"time":"20250518","count":2},{"time":"20250519","count":20},{"time":"20250520","count":14},{"time":"20250521","count":19},{"time":"20250522","count":10},{"time":"20250523","count":10},{"time":"20250524","count":6},{"time":"20250525","count":3},{"time":"20250526","count":15},{"time":"20250527","count":18},{"time":"20250528","count":19},{"time":"20250529","count":22},{"time":"20250530","count":16},{"time":"20250531","count":1},{"time":"20250601","count":2},{"time":"20250602","count":15},{"time":"20250603","count":18},{"time":"20250604","count":13},{"time":"20250605","count":13},{"time":"20250606","count":25},{"time":"20250607","count":6},{"time":"20250608","count":2},{"time":"20250609","count":13},{"time":"20250610","count":16},{"time":"20250611","count":26},{"time":"20250612","count":11},{"time":"20250613","count":19},{"time":"20250614","count":6},{"time":"20250616","count":14},{"time":"20250617","count":32},{"time":"20250618","count":25},{"time":"20250619","count":22},{"time":"20250620","count":11},{"time":"20250621","count":4},{"time":"20250622","count":2},{"time":"20250623","count":11},{"time":"20250624","count":23},{"time":"20250625","count":25},{"time":"20250626","count":18},{"time":"20250627","count":19},{"time":"20250628","count":2},{"time":"20250629","count":1},{"time":"20250630","count":22},{"time":"20250701","count":27},{"time":"20250702","count":31},{"time":"20250703","count":14},{"time":"20250704","count":22},{"time":"20250705","count":4},{"time":"20250706","count":5},{"time":"20250707","count":13},{"time":"20250708","count":22},{"time":"20250709","count":23},{"time":"20250710","count":16},{"time":"20250711","count":25},{"time":"20250712","count":2},{"time":"20250713","count":4},{"time":"20250714","count":21},{"time":"20250715","count":13},{"time":"20250716","count":28},{"time":"20250717","count":14},{"time":"20250718","count":22},{"time":"20250719","count":13},{"time":"20250720","count":4},{"time":"20250721","count":15},{"time":"20250722","count":17},{"time":"20250723","count":23},{"time":"20250724","count":17},{"time":"20250725","count":15},{"time":"20250726","count":2},{"time":"20250728","count":19},{"time":"20250729","count":25},{"time":"20250730","count":21},{"time":"20250731","count":20},{"time":"20250801","count":16},{"time":"20250802","count":2},{"time":"20250804","count":23},{"time":"20250805","count":18},{"time":"20250806","count":15},{"time":"20250807","count":18},{"time":"20250808","count":17},{"time":"20250809","count":1},{"time":"20250810","count":2},{"time":"20250811","count":17},{"time":"20250812","count":15},{"time":"20250813","count":20},{"time":"20250814","count":22},{"time":"20250815","count":10},{"time":"20250816","count":8},{"time":"20250817","count":2},{"time":"20250818","count":17},{"time":"20250819","count":18},{"time":"20250820","count":19},{"time":"20250821","count":19},{"time":"20250822","count":24},{"time":"20250823","count":3},{"time":"20250824","count":2},{"time":"20250825","count":13},{"time":"20250826","count":16},{"time":"20250827","count":9},{"time":"20250828","count":19},{"time":"20250829","count":19},{"time":"20250830","count":3},{"time":"20250901","count":14},{"time":"20250902","count":27},{"time":"20250903","count":16},{"time":"20250904","count":24},{"time":"20250905","count":49},{"time":"20250906","count":3},{"time":"20250907","count":3},{"time":"20250908","count":14},{"time":"20250909","count":23},{"time":"20250910","count":18},{"time":"20250911","count":25},{"time":"20250912","count":7},{"time":"20250913","count":3},{"time":"20250915","count":11},{"time":"20250916","count":21},{"time":"20250917","count":16},{"time":"20250918","count":24},{"time":"20250919","count":21},{"time":"20250920","count":1},{"time":"20250922","count":20},{"time":"20250923","count":21},{"time":"20250924","count":15},{"time":"20250925","count":13},{"time":"20250926","count":14},{"time":"20250927","count":2},{"time":"20250929","count":14},{"time":"20250930","count":18},{"time":"20251001","count":16},{"time":"20251002","count":9},{"time":"20251003","count":22},{"time":"20251004","count":5},{"time":"20251005","count":2},{"time":"20251006","count":10},{"time":"20251007","count":23},{"time":"20251008","count":23},{"time":"20251009","count":8},{"time":"20251010","count":13},{"time":"20251011","count":2},{"time":"20251013","count":22},{"time":"20251014","count":10},{"time":"20251015","count":14},{"time":"20251016","count":12},{"time":"20251017","count":19},{"time":"20251018","count":2},{"time":"20251019","count":2},{"time":"20251020","count":5},{"time":"20251021","count":12},{"time":"20251022","count":13},{"time":"20251023","count":18},{"time":"20251024","count":21},{"time":"20251025","count":1},{"time":"20251027","count":25},{"time":"20251028","count":13},{"time":"20251029","count":21},{"time":"20251030","count":22},{"time":"20251031","count":19},{"time":"20251101","count":2},{"time":"20251102","count":1},{"time":"20251103","count":15},{"time":"20251104","count":12},{"time":"20251105","count":19},{"time":"20251106","count":7},{"time":"20251107","count":15},{"time":"20251109","count":3},{"time":"20251110","count":11},{"time":"20251111","count":19},{"time":"20251112","count":22},{"time":"20251113","count":16},{"time":"20251114","count":11},{"time":"20251115","count":3},{"time":"20251117","count":13},{"time":"20251118","count":25},{"time":"20251119","count":13},{"time":"20251120","count":18},{"time":"20251121","count":20},{"time":"20251122","count":2},{"time":"20251123","count":3},{"time":"20251124","count":12},{"time":"20251125","count":26},{"time":"20251126","count":21},{"time":"20251127","count":14},{"time":"20251128","count":22},{"time":"20251129","count":3},{"time":"20251201","count":23},{"time":"20251202","count":10},{"time":"20251203","count":13},{"time":"20251204","count":15},{"time":"20251205","count":9},{"time":"20251206","count":1},{"time":"20251207","count":1},{"time":"20251208","count":14},{"time":"20251209","count":15},{"time":"20251210","count":9},{"time":"20251211","count":14},{"time":"20251212","count":11},{"time":"20251214","count":6},{"time":"20251215","count":11},{"time":"20251216","count":20},{"time":"20251217","count":16},{"time":"20251218","count":18},{"time":"20251219","count":17},{"time":"20251220","count":1},{"time":"20251221","count":8},{"time":"20251222","count":22},{"time":"20251223","count":9},{"time":"20251224","count":20},{"time":"20251225","count":7},{"time":"20251226","count":7},{"time":"20251227","count":4},{"time":"20251228","count":2},{"time":"20251229","count":17},{"time":"20251230","count":10},{"time":"20251231","count":11}],"recentPublications":[{"pmid":"42001241","title":"Azo(bis)pyrazole-Ciprofloxacin Conjugates: Tuning Photopharmacological Performance Through Structural Engineering.","authors":"Bhunia S, Jana SK, Guha D, Saha S, Mandal S","journal":"ChemMedChem","pubDate":"2026 Apr 14"},{"pmid":"42000672","title":"Influence of different media and incubation times for determining the minimum inhibitory concentrations of gepotidacin, ciprofloxacin and ceftriaxone against Neisseria gonorrhoeae.","authors":"Koeth LM, DiFranco-Fisher J, West J, Scangarella-Oman NE","journal":"Diagn Microbiol Infect Dis","pubDate":"2026 Apr 8"},{"pmid":"41996059","title":"An inhalable dry powder co-delivery system of ciprofloxacin liposomes and S-nitrosoglutathione for synergistic treatment of Pseudomonas aeruginosa biofilm-associated pulmonary infections.","authors":"Ran F, Chai G","journal":"Drug Deliv Transl Res","pubDate":"2026 Apr 17"},{"pmid":"41995909","title":"Enhanced antibacterial, antibiofilm, and antioxidant potential of ciprofloxacin-loaded SDS-capped silver nanoparticles against resistant bacterial strains.","authors":"Fareed M, Farid N, Dar MS, Ali K, Bashir A","journal":"Discov Nano","pubDate":"2026 Apr 17"},{"pmid":"41988992","title":"Risk of Achilles tendon rupture following single-dose ciprofloxacin use in transrectal prostate biopsies.","authors":"Runnaes M, Lampa E, Styrke J, Lundström KJ","journal":"Scand J Urol","pubDate":"2026 Apr 16"},{"pmid":"41988171","title":"Ciprofloxacin-induced microbiota dysbiosis triggers seizure susceptibility through the microbiota-gut-brain axis.","authors":"Zou Q, Zhang Y, Zou S, Li Y, Li H","journal":"Front Immunol","pubDate":"2026"},{"pmid":"41987060","title":"Efficacy of lytic bacteriophages isolated from sewage-treatment plants in Mbarara district, Uganda against ciprofloxacin-resistant Salmonella Typhi in a mice infection model.","authors":"Bindyo PN, Ibrahim N, Nabona J, Udom GJ, Nakavuma JL","journal":"BMC Infect Dis","pubDate":"2026 Apr 15"},{"pmid":"41984198","title":"Chrysin mitigates ciprofloxacin-induced nephrotoxicity: associations with notch/HES1 signaling, inflammation, and a ferroptosis-related molecular signature.","authors":"Gönen MÖ, Akaras N, Şimşek H, Kandemir Ö, Çağlayan C","journal":"Naunyn Schmiedebergs Arch Pharmacol","pubDate":"2026 Apr 15"},{"pmid":"41968016","title":"Retraction notice to \"Improving wheat physio-biochemical attributes in ciprofloxacin-polluted saline soil using nZVI-modified biochar\" [Ecotoxicol. Environ. Saf., 286 C, (2024) 117202].","authors":"Murtaza G, Usman M, Ahmed Z, Hyder S, Alwahibi MS","journal":"Ecotoxicol Environ Saf","pubDate":"2026 Apr 11"},{"pmid":"41964551","title":"Chlorpromazine potentiates levofloxacin and ciprofloxacin activity against Klebsiella pneumoniae isolates.","authors":"Gun MA, Yildirim K, Atas C, Uzuner F, Coban AY","journal":"Future Microbiol","pubDate":"2026 Apr 11"}],"rxnormFormulations":[{"tty":"SBD","name":"ciprofloxacin 3 MG/ML Ophthalmic Solution [Ciloxan]","rxcui":"103943","synonym":"Ciloxan 0.3 % Ophthalmic Solution"},{"tty":"SBD","name":"ciprofloxacin 60 MG/ML Otic Suspension [Otiprio]","rxcui":"1740002","synonym":"Otiprio 6 % Otic Suspension"},{"tty":"SBD","name":"ciprofloxacin 3 MG/ML / fluocinolone acetonide 0.25 MG/ML Otic Solution [Otovel]","rxcui":"1792391","synonym":"Otovel (ciprofloxacin 0.3 % / fluocinolone acetonide 0.025 % ) Otic Solution"},{"tty":"SBD","name":"ciprofloxacin 250 MG Oral Tablet [Cipro]","rxcui":"205769","synonym":"Cipro 250 MG Oral Tablet"},{"tty":"SBD","name":"ciprofloxacin 500 MG Oral Tablet [Cipro]","rxcui":"205770","synonym":"Cipro 500 MG Oral Tablet"},{"tty":"SBD","name":"ciprofloxacin 50 MG/ML Oral Suspension [Cipro]","rxcui":"213224","synonym":"Cipro 50 MG/ML Oral Suspension"},{"tty":"SBD","name":"ciprofloxacin 100 MG/ML Oral Suspension [Cipro]","rxcui":"213226","synonym":"Cipro 100 MG/ML Oral Suspension"},{"tty":"SBD","name":"ciprofloxacin 0.003 MG/MG Ophthalmic Ointment [Ciloxan]","rxcui":"213307","synonym":"Ciloxan 0.3 % Ophthalmic Ointment"},{"tty":"SBD","name":"ciprofloxacin 2 MG/ML / hydrocortisone 10 MG/ML Otic Suspension [Cipro HC]","rxcui":"213320","synonym":"Cipro HC 2/10 Otic Suspension"},{"tty":"SBD","name":"ciprofloxacin 3 MG/ML / dexamethasone 1 MG/ML Otic Suspension [Ciprodex]","rxcui":"404630","synonym":"Ciprodex (ciprofloxacin 0.3 % / dexamethasone 0.1 % ) Otic Suspension"},{"tty":"SBD","name":"24 HR ciprofloxacin 500 MG Extended Release Oral Tablet [Proquin]","rxcui":"672912","synonym":"24 HR Proquin 500 MG Extended Release Oral Tablet"},{"tty":"SBD","name":"24 HR ciprofloxacin 1000 MG Extended Release Oral Tablet [Cipro]","rxcui":"847488","synonym":"24 HR Cipro 1000 MG Extended Release Oral Tablet"},{"tty":"SBD","name":"ciprofloxacin 2 MG/ML Otic Solution [Cetraxal]","rxcui":"848960","synonym":"Cetraxal 0.2 % Otic Solution"},{"tty":"SBD","name":"24 HR ciprofloxacin 500 MG Extended Release Oral Tablet [Cipro]","rxcui":"899122","synonym":"24 HR Cipro 500 MG Extended Release Oral Tablet"},{"tty":"SCD","name":"100 ML ciprofloxacin 2 MG/ML Injection","rxcui":"1665210","synonym":"ciprofloxacin 200 MG per 100 ML Injection"},{"tty":"SCD","name":"200 ML ciprofloxacin 2 MG/ML Injection","rxcui":"1665212","synonym":"ciprofloxacin 400 MG per 200 ML Injection"},{"tty":"SCD","name":"40 ML ciprofloxacin 10 MG/ML Injection","rxcui":"1665229","synonym":"ciprofloxacin 400 MG per 40 ML Injection"},{"tty":"SCD","name":"ciprofloxacin 60 MG/ML Otic Suspension","rxcui":"1739997","synonym":"ciprofloxacin 6 % Otic Suspension"},{"tty":"SCD","name":"ciprofloxacin 3 MG/ML / fluocinolone acetonide 0.25 MG/ML Otic Solution","rxcui":"1792386","synonym":"ciprofloxacin 0.3 % / fluocinolone acetonide 0.025 % Otic Solution"},{"tty":"SCD","name":"ciprofloxacin 250 MG Oral Tablet","rxcui":"197511","synonym":"ciprofloxacin 250 MG (as ciprofloxacin HCl 297 MG) Oral Tablet"},{"tty":"SCD","name":"ciprofloxacin 750 MG Oral Tablet","rxcui":"197512","synonym":"ciprofloxacin (as ciprofloxacin hydrochloride) 750 MG Oral Tablet"},{"tty":"SCD","name":"ciprofloxacin 100 MG Oral Tablet","rxcui":"199370","synonym":"ciprofloxacin (as ciprofloxacin hydrochloride) 100 MG Oral Tablet"},{"tty":"SCD","name":"ciprofloxacin 2 MG/ML / hydrocortisone 10 MG/ML Otic Suspension","rxcui":"309305","synonym":"ciprofloxacin 0.2 % / hydrocortisone 1 % Otic Suspension"},{"tty":"SCD","name":"ciprofloxacin 0.003 MG/MG Ophthalmic Ointment","rxcui":"309306","synonym":"ciprofloxacin 0.3 % Ophthalmic Ointment"},{"tty":"SCD","name":"ciprofloxacin 3 MG/ML Ophthalmic Solution","rxcui":"309307","synonym":"ciprofloxacin 0.3 % Ophthalmic Solution"},{"tty":"SCD","name":"ciprofloxacin 50 MG/ML Oral Suspension","rxcui":"309308","synonym":"ciprofloxacin 250 MG per 5 ML Oral Suspension"},{"tty":"SCD","name":"ciprofloxacin 500 MG Oral Tablet","rxcui":"309309","synonym":"ciprofloxacin (as ciprofloxacin HCl) 500 MG Oral Tablet"},{"tty":"SCD","name":"ciprofloxacin 100 MG/ML Oral Suspension","rxcui":"309310","synonym":"ciprofloxacin 500 MG per 5 ML Oral Suspension"},{"tty":"SCD","name":"24 HR ciprofloxacin 500 MG Extended Release Oral Tablet","rxcui":"359383","synonym":"ciprofloxacin 500 MG 24 HR Extended Release Oral Tablet"},{"tty":"SCD","name":"ciprofloxacin 3 MG/ML / dexamethasone 1 MG/ML Otic Suspension","rxcui":"403908","synonym":"ciprofloxacin 0.3 % / dexamethasone 0.1 % Otic Suspension"},{"tty":"SCD","name":"24 HR ciprofloxacin 1000 MG Extended Release Oral Tablet","rxcui":"403921","synonym":"ciprofloxacin 1000 MG 24 HR Extended Release Oral Tablet"},{"tty":"SCD","name":"ciprofloxacin 2 MG/ML Otic Solution","rxcui":"848956","synonym":"ciprofloxacin 0.2 % Otic Solution"}],"storageAndHandling":"","participantFlowData":[],"faersSexDistribution":[{"term":2,"count":50172},{"term":1,"count":36170},{"term":0,"count":321}],"genericManufacturers":11,"_genericFilersChecked":true,"structuredTrialResults":[{"hr":"0.9764","nctId":"NCT04067011","phase":"PHASE2","pValue":"","ciLower":"0.8895","ciUpper":"1.0718","endpoint":"Ratio of Ciprofloxacin Area Under the Curve From 0 to 12 Hours (AUC0-12h) and Maximum Concentration (Cmax) on Days 8 and 35","enrollment":210}],"genericManufacturerList":["Baxter Hlthcare","Baxter Hlthcare Corp","Bedford","Bedford Labs","Chartwell","Dr Reddys","Fresenius Kabi Usa","Hikma Farmaceutica","Hospira","Inforlife","Teva Pharms"],"faersSeriousnessBreakdown":[{"term":1,"count":78927},{"term":2,"count":15875}],"genericFilers":[],"labelChanges":[],"biosimilarFilings":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"trials":[],"biosimilars":[],"latestUpdates":[],"offLabel":[],"developmentCodes":[],"aliases":[],"status":"approved","companyName":"Alk Abello","companyId":"pfizer","modality":"Small molecule","firstApprovalDate":"1987","enrichmentLevel":5,"visitCount":9,"regulatoryByCountry":[{"country_code":"CA","regulator":"Health Canada","status":"approved","approval_date":null,"mah":"","brand_name_local":"","application_number":""},{"country_code":"US","regulator":"FDA","status":"approved","approval_date":null,"mah":null,"brand_name_local":null,"application_number":null}],"pricingByCountry":[{"country_code":"UN","currency":"USD","price_amount":"477.00","price_per":"year","price_type":"NADAC","annual_cost_usd":null,"reimbursement_status":null},{"country_code":"UN","currency":"USD","price_amount":"477.00","price_per":"year","price_type":"NADAC","annual_cost_usd":null,"reimbursement_status":null},{"country_code":"UN","currency":"USD","price_amount":"477.00","price_per":"year","price_type":"NADAC","annual_cost_usd":null,"reimbursement_status":null},{"country_code":"UN","currency":"USD","price_amount":"477.00","price_per":"year","price_type":"NADAC","annual_cost_usd":null,"reimbursement_status":null}],"trialStats":{"total":42,"withResults":15},"validation":{"fieldsValidated":7,"lastValidatedAt":"2026-04-20T08:34:45.560273+00:00","fieldsConflicting":0,"overallConfidence":0.95},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":false,"score":3}}