{"id":"cinnapoietin","safety":{"commonSideEffects":[{"rate":null,"effect":"Hypertension"},{"rate":null,"effect":"Thromboembolism"},{"rate":null,"effect":"Headache"},{"rate":null,"effect":"Injection site reactions"},{"rate":null,"effect":"Pure red cell aplasia (rare)"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"CinnaPoietin is a recombinant human erythropoietin (rHuEPO) analog developed by Cinnagen, a Iranian pharmaceutical company. It binds to erythropoietin receptors on erythroid progenitor cells in bone marrow, promoting their proliferation and differentiation into mature red blood cells. This mechanism is used to treat anemia associated with chronic kidney disease, cancer chemotherapy, and other conditions.","oneSentence":"CinnaPoietin is an erythropoiesis-stimulating agent that mimics erythropoietin to stimulate red blood cell production.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:05:55.216Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Anemia associated with chronic kidney disease"},{"name":"Chemotherapy-induced anemia"},{"name":"Anemia in patients with cancer"}]},"trialDetails":[{"nctId":"NCT03408639","phase":"PHASE3","title":"Comparing Efficacy and Safety of CinnaGen Beta Erythropoietin (CinnaPoietin®) Versus Eprex® on the Treatment of Anemia in ESRD Hemodialysis Patients","status":"COMPLETED","sponsor":"Cinnagen","startDate":"2016-06-22","conditions":"Anemia in End-Stage Renal Disease","enrollment":156}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":2,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Beta erythropoietin"],"phase":"phase_3","status":"active","brandName":"CinnaPoietin®","genericName":"CinnaPoietin®","companyName":"Cinnagen","companyId":"cinnagen","modality":"Small molecule","firstApprovalDate":"","aiSummary":"CinnaPoietin is an erythropoiesis-stimulating agent that mimics erythropoietin to stimulate red blood cell production. Used for Anemia associated with chronic kidney disease, Chemotherapy-induced anemia, Anemia in patients with cancer.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":1,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}