{"id":"cinchocaine","rwe":[{"pmid":"41470102","year":"2025","title":"Effects of Various Local Antibacterial Preparations on Bacterial Density in Pharyngeal and Tonsillar Mucosa of Patients with Acute Pharyngitis.","finding":"","journal":"Medicina (Kaunas, Lithuania)","studyType":"Clinical Study"},{"pmid":"31869179","year":"2026","title":"Saddle Anesthetic Block.","finding":"","journal":"","studyType":"Clinical Study"},{"pmid":"36080279","year":"2022","title":"Determination of Local Anesthetic Drugs in Human Plasma Using Magnetic Solid-Phase Extraction Coupled with High-Performance Liquid Chromatography.","finding":"","journal":"Molecules (Basel, Switzerland)","studyType":"Clinical Study"},{"pmid":"34765003","year":"2021","title":"Clinical Pilot Study of Rectal Suppository Containing Combined Extract of Cissus quadrangularis Linn. and Acmella paniculata (Wall ex. DC.) R. K. 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If the symptoms being treated does not subside or redness, irritation, swelling, bleeding or other symptoms develop or increase, discontinue use and ask a doctor."],"questions":["Questions or Comments? call toll-free 1(877)225-6999 Manufactured for Akron Pharma, Inc., Fairfeld, NJ - 07004"],"effective_time":"20250112","active_ingredient":["Drug Facts Active ingredient Purpose Dibucaine 1% Hemorrhoidal ointment"],"inactive_ingredient":["Inactive Ingredients Lanolin, Light Mineral Oil, Purified water, White Petrotalum"],"storage_and_handling":["Store at room temperature 20 o -25 o C (68 o -77 o F)"],"indications_and_usage":["Do not use in children under 2 years at age in or near the eyes"],"dosage_and_administration":["Directions adults and children 12 years and over: if possible, clean the affected area with mild soap and wann water and nnse thoroughly. Dry by patting or blotting withh toilet tissue or a soft cloth before applying. apply externally to the affected area up to 3 or 4 times daily children under 12 years of age: ask a doctor"],"spl_product_data_elements":["Dibucaine Dibucaine DIBUCAINE DIBUCAINE LANOLIN LIGHT MINERAL OIL WATER WHITE PETROLATUM"],"keep_out_of_reach_of_children":["When using this product avoid contact wnh eyes do not use more than directed unless directed by a doctor do not put this product into the rectum by using fingers or any mechanical device or applicator lf pregnant or breast feeding , ask a health care professional before use. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away. Stop use and ask a doctor if bleeding occurs condition worsens or does not improve wnhin 7 days"],"package_label_principal_display_panel":["1oz 2oz"]},"tags":[{"label":"Standardized Chemical Allergen","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Sodium channel alpha subunits; brain (Types I, II, III)","category":"target"},{"label":"SCN1A","category":"gene"},{"label":"SCN2A","category":"gene"},{"label":"SCN3A","category":"gene"},{"label":"C05AD04","category":"atc"},{"label":"Topical","category":"route"},{"label":"Buccal","category":"route"},{"label":"Cream","category":"form"},{"label":"Gel","category":"form"},{"label":"Ointment","category":"form"},{"label":"Active","category":"status"},{"label":"Itching of skin","category":"indication"},{"label":"Minor Skin Wound Pain","category":"indication"},{"label":"Skin irritation","category":"indication"},{"label":"Anesthetics","category":"pharmacology"},{"label":"Anesthetics, 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Among the most potent and toxic of the long-acting local anesthetics, current use of cinchocaine is generally restricted to spinal and topical anesthesia. 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