{"id":"cicrotoic-acid","rwe":[{"pmid":"7335221","year":"1981","title":"[Effect of cicrotoic acid on bile flow and lipid composition of human bile].","finding":"","journal":"Minerva dietologica e gastroenterologica","studyType":"Clinical Study"}],"tags":[{"label":"cicrotoic acid","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"accroibile","offLabel":[],"synonyms":["accroibile","beta-cyclohexylcrotonic acid","cicrotoic acid","cyclohexaneacrylic acid"],"timeline":[],"approvals":[],"brandName":"Accroibile","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"cicrotoic acid","explanation":"Imagine your body's cells have locks on them, and cicrotoic acid has a key that fits into those locks. When it binds to the lock, it triggers a series of events that help to treat the condition it's intended for. This is a simplified explanation of how cicrotoic acid is thought to work at a molecular level.","oneSentence":"Cicrotoic acid is thought to work by interacting with a specific molecular target to produce its therapeutic effect.","technicalDetail":"Cicrotoic acid is a small molecule that binds to a specific protein target, modulating its activity and leading to a therapeutic response."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3710","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=CICROTOIC ACID","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T10:00:23.403941","biosimilars":[],"competitors":[],"genericName":"cicrotoic acid","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"LMP5BMU9EF","CHEBI":"CHEBI:134801","INN_ID":"2540","UMLSCUI":"C0615712","ChEMBL_ID":"CHEMBL3989888","PUBCHEM_CID":"71704","MESH_SUPPLEMENTAL_RECORD_UI":"C033648"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":1,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"1981 Oct-Dec","pmid":"7335221","title":"[Effect of cicrotoic acid on bile flow and lipid composition of human bile].","journal":"Minerva dietologica e gastroenterologica"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Cicrotoic acid is a small molecule drug of the cicrotoic acid class, but its details are limited. Its original developer and current owner are unknown. The target and approved indications of cicrotoic acid are also not specified. Its commercial status, including patent status and generic availability, is unclear. Further research is needed to understand its pharmacokinetics and safety profile.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}