{"id":"ciclosprin-a","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Nausea"},{"rate":"5-10%","effect":"Diarrhea"},{"rate":"5-10%","effect":"Headache"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"Ciclosprin A works by binding to the T cell receptor, preventing the activation of T cells and subsequent immune response. This mechanism is crucial in preventing organ rejection in transplant patients.","oneSentence":"Ciclosprin A is an immunosuppressive agent that inhibits the activity of T cells.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T03:08:11.215Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of organ rejection in transplant patients"}]},"trialDetails":[{"nctId":"NCT01527240","phase":"PHASE2","title":"Neuroprotection Impact of Cyclosporin A in Cerebral Infarction","status":"COMPLETED","sponsor":"Hospices Civils de Lyon","startDate":"2009-10","conditions":"Stroke","enrollment":126}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_2","status":"active","brandName":"Ciclosprin A","genericName":"Ciclosprin A","companyName":"Hospices Civils de Lyon","companyId":"hospices-civils-de-lyon","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Ciclosprin A is an immunosuppressive agent that inhibits the activity of T cells. Used for Prevention of organ rejection in transplant patients.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}