{"id":"ciclobendazole","rwe":[{"pmid":"33842429","year":"2021","title":"Revisiting Activity of Some Nocodazole Analogues as a Potential Anticancer Drugs Using Molecular Docking and DFT Calculations.","finding":"","journal":"Frontiers in chemistry","studyType":"Clinical Study"},{"pmid":"8094587","year":"1993","title":"Experimental chemotherapy of filariasis: comparative evaluation of the efficacy of filaricidal compounds in Mastomys coucha infected with Litomosoides carinii, Acanthocheilonema viteae, Brugia malayi and B. pahangi.","finding":"","journal":"Acta tropica","studyType":"Clinical Study"},{"pmid":"15463317","year":"1990","title":"Use of benzimidazole chemotherapy in human helminthiases: indications and efficacy.","finding":"","journal":"Parasitology today (Personal ed.)","studyType":"Clinical Study"},{"pmid":"493246","year":"1979","title":"[Pinworm infection in kindergartens of Basel (author's transl)].","finding":"","journal":"Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis","studyType":"Clinical Study"},{"pmid":"369076","year":"1978","title":"Comparative trial on the therapeutic effectiveness of the new anthelmintic drug: ciclobendazole.","finding":"","journal":"Tropenmedizin und Parasitologie","studyType":"Clinical Study"}],"tags":[{"label":"ciclobendazole","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"P02CA04","category":"atc"},{"label":"Active","category":"status"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"cyclobendazole","offLabel":[],"synonyms":["cyclobendazole","ciclobendazole"],"timeline":[],"approvals":[],"brandName":"Cyclobendazole","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"ciclobendazole","explanation":"Imagine your body's cells are like a city with many different buildings. Cyclobendazole is like a key that fits into a specific lock on one of those buildings, but we don't know which building or lock it's meant for. By binding to this target, it may help to treat certain diseases, but more research is needed to understand how it works.","oneSentence":"Cyclobendazole works by binding to a specific target, although its exact mechanism of action is currently unknown.","technicalDetail":"Cyclobendazole is a small molecule that interacts with a specific protein or receptor, although the exact nature of this interaction is currently unknown."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3120","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=ciclobendazole","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T09:59:39.832734","biosimilars":[],"competitors":[{"drugName":"mebendazole","drugSlug":"mebendazole","fdaApproval":"1974-06-28","genericCount":1,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"thiabendazole","drugSlug":"thiabendazole","fdaApproval":"1967-04-07","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"albendazole","drugSlug":"albendazole","fdaApproval":"1996-06-11","genericCount":9,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"fenbendazole","drugSlug":"fenbendazole","fdaApproval":"","relationship":"same-class"}],"genericName":"ciclobendazole","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"mebendazole","brandName":"mebendazole","genericName":"mebendazole","approvalYear":"1974","relationship":"same-class"},{"drugId":"thiabendazole","brandName":"thiabendazole","genericName":"thiabendazole","approvalYear":"1967","relationship":"same-class"},{"drugId":"albendazole","brandName":"albendazole","genericName":"albendazole","approvalYear":"1996","relationship":"same-class"},{"drugId":"fenbendazole","brandName":"fenbendazole","genericName":"fenbendazole","approvalYear":"","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"JF3KQ40J31","CHEBI":"CHEBI:135067","INN_ID":"3570","UMLSCUI":"C0055709","ChEMBL_ID":"CHEMBL1788401","KEGG_DRUG":"D03623","DRUGBANK_ID":"DB13465","PUBCHEM_CID":"35803","MESH_SUPPLEMENTAL_RECORD_UI":"C014415"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":8,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"P02CA04","allCodes":["P02CA04"]},"biosimilarFilings":[],"recentPublications":[{"date":"2021","pmid":"33842429","title":"Revisiting Activity of Some Nocodazole Analogues as a Potential Anticancer Drugs Using Molecular Docking and DFT Calculations.","journal":"Frontiers in chemistry"},{"date":"1993 Jan","pmid":"8094587","title":"Experimental chemotherapy of filariasis: comparative evaluation of the efficacy of filaricidal compounds in Mastomys coucha infected with Litomosoides carinii, Acanthocheilonema viteae, Brugia malayi and B. pahangi.","journal":"Acta tropica"},{"date":"1990 Apr","pmid":"15463317","title":"Use of benzimidazole chemotherapy in human helminthiases: indications and efficacy.","journal":"Parasitology today (Personal ed.)"},{"date":"1979 Sep 11","pmid":"493246","title":"[Pinworm infection in kindergartens of Basel (author's transl)].","journal":"Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis"},{"date":"1978 Dec","pmid":"369076","title":"Comparative trial on the therapeutic effectiveness of the new anthelmintic drug: ciclobendazole.","journal":"Tropenmedizin und Parasitologie"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Cyclobendazole, also known as ciclobendazole, is a small molecule drug of the ciclobendazole class. Unfortunately, there is limited information available on this compound. It is not clear what specific target it binds to or what diseases it treats. Cyclobendazole's commercial status is also unknown, with no information available on its patent status or generic manufacturers. Further research is needed to understand its pharmacological properties and clinical applications.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}