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This mechanism allows for procedural sedation and anesthesia while maintaining spontaneous respiration and protective airway reflexes.","oneSentence":"CI-581-a is a dissociative anesthetic that acts as an NMDA receptor antagonist to produce rapid-onset anesthesia and analgesia.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:05:49.081Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Anesthesia induction and maintenance"},{"name":"Procedural sedation and analgesia"}]},"trialDetails":[{"nctId":"NCT06867068","phase":"PHASE1","title":"Comparison of Two Intravenous Drug Combinations for Ambulatory Oral & Maxillofacial Surgery","status":"COMPLETED","sponsor":"Albert Einstein College of Medicine","startDate":"2016-10-04","conditions":"Anesthesia, Tooth Extraction","enrollment":73},{"nctId":"NCT04751175","phase":"PHASE4","title":"Management of Pain in Lumbar Arthrodesis","status":"COMPLETED","sponsor":"Institut d'Investigació Biomèdica de Girona 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