{"id":"chop-cmab304","safety":{"commonSideEffects":[]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"While the exact molecular target of CMAB304 is not widely disclosed in public literature, it is developed as an immunotherapeutic monoclonal antibody by Shanghai CP Guojian Pharmaceutical. As a Phase 3 candidate, it is likely designed to modulate immune responses against cancer cells, potentially through checkpoint inhibition or direct tumor antigen targeting.","oneSentence":"CMAB304 is a monoclonal antibody that targets and inhibits a specific immune checkpoint or tumor-associated antigen to enhance anti-tumor immunity.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:05:48.087Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Cancer (specific indication not publicly detailed)"}]},"trialDetails":[{"nctId":"NCT01459887","phase":"PHASE3","title":"Study of Recombinant Human-Mouse Chimeric Anti-CD20 Monoclonal Antibody to Treat Non-hodgkin's Lymphoma","status":"COMPLETED","sponsor":"Shanghai CP Guojian Pharmaceutical Co., Ltd.","startDate":"2006-09","conditions":"Diffuse Large B Cell Lymphoma","enrollment":278}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["cyclophosphamide, doxorubicin, vincristine, prednisone"],"phase":"phase_3","status":"active","brandName":"CHOP, CMAB304","genericName":"CHOP, CMAB304","companyName":"Shanghai CP Guojian Pharmaceutical Co., Ltd.","companyId":"shanghai-cp-guojian-pharmaceutical-co-ltd","modality":"Small molecule","firstApprovalDate":"","aiSummary":"CMAB304 is a monoclonal antibody that targets and inhibits a specific immune checkpoint or tumor-associated antigen to enhance anti-tumor immunity. Used for Cancer (specific indication not publicly detailed).","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":true,"score":3}}