{"id":"choline-dehydrocholate","rwe":[{"pmid":"5016305","year":"1972","title":"Effect of bile salts on hepatic phosphatidylcholine synthesis and transport into rat bile.","finding":"","journal":"Journal of lipid research","studyType":"Clinical Study"},{"pmid":"14346314","year":"1965","title":"[EFFECTS OF CHOLINE DEHYDROCHOLATE ON HEPATIC AND BLOOD CHOLESTEROL IN MALE WISTAR RATS].","finding":"","journal":"La Ricerca scientifica. 2. ser., pt. 2: Rendiconti. Sezione B: Biologica","studyType":"Clinical Study"},{"pmid":"18871854","year":"1948","title":"B diethylaminoethyl dehydrocholate in the treatment of fibrositis.","finding":"","journal":"Irish journal of medical science","studyType":"Clinical Study"}],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Antimetabolites","category":"pharmacology"},{"label":"Central Nervous System Agents","category":"pharmacology"},{"label":"Cholagogues and Choleretics","category":"pharmacology"},{"label":"Gastrointestinal Agents","category":"pharmacology"},{"label":"Hypolipidemic Agents","category":"pharmacology"},{"label":"Lipid Regulating Agents","category":"pharmacology"},{"label":"Lipotropic Agents","category":"pharmacology"},{"label":"Nootropic Agents","category":"pharmacology"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"biscolan","offLabel":[],"synonyms":["choline dehydrocholate","biscolan"],"timeline":[],"approvals":[],"brandName":"Biscolan","ecosystem":[],"mechanism":{"modality":"Small Molecule","explanation":"Think of Biscolan like a key that fits into a lock. When it binds to its target, it can help to turn off or slow down certain processes in the body that are involved in a particular disease or condition. This can help to alleviate symptoms and improve quality of life for people taking the medication.","oneSentence":"Biscolan works by binding to a specific target, although the identity of this target is currently unknown.","technicalDetail":"Biscolan is a cholate derivative that modulates the activity of its target through a mechanism that is not yet fully understood. Further research is needed to elucidate the precise molecular interactions involved in its action."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3708","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=choline dehydrocholate","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T09:35:57.219111","biosimilars":[],"competitors":[],"genericName":"choline dehydrocholate","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"MMSL":"4436","NDDF":"001203","UNII":"2Z092M53MS","CHEBI":"CHEBI:15354","VANDF":"4017699","INN_ID":"157","RXNORM":"2449","UMLSCUI":"C0008405","DRUGBANK_ID":"DB00122","PUBCHEM_CID":"21155855","SNOMEDCT_US":"111156002","MESH_DESCRIPTOR_UI":"D002794"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":3,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"1972 Mar","pmid":"5016305","title":"Effect of bile salts on hepatic phosphatidylcholine synthesis and transport into rat bile.","journal":"Journal of lipid research"},{"date":"1965 Jan-Mar","pmid":"14346314","title":"[EFFECTS OF CHOLINE DEHYDROCHOLATE ON HEPATIC AND BLOOD CHOLESTEROL IN MALE WISTAR RATS].","journal":"La Ricerca scientifica. 2. ser., pt. 2: Rendiconti. Sezione B: Biologica"},{"date":"1948 Jul","pmid":"18871854","title":"B diethylaminoethyl dehydrocholate in the treatment of fibrositis.","journal":"Irish journal of medical science"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Biscolan, also known as choline dehydrocholate, is a small molecule modality with unknown drug class and target. Its commercial status is unclear, and it is not known whether it is FDA approved or off-patent. The approved indications for Biscolan are also unknown. As a small molecule, Biscolan is likely to be administered orally, but its pharmacokinetic properties, including half-life and bioavailability, are not well-documented. Further research is needed to fully understand the safety and efficacy of Biscolan.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}