{"id":"chloroprednisone","rwe":[],"tags":[{"label":"chloroprednisone","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"S01CA09","category":"atc"},{"label":"Active","category":"status"}],"phase":"unknown","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":["chloroprednisone"],"offLabel":[],"synonyms":["chloroprednisone"],"timeline":[],"approvals":[],"ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"chloroprednisone","explanation":"Imagine your body's immune system as a fire that can sometimes get out of control. Cortisol is like a fire extinguisher that helps to calm down the flames. Chloroprednisone is a synthetic version of cortisol that can be used to treat conditions where the immune system is overactive, such as inflammation and autoimmune diseases.","oneSentence":"Chloroprednisone works by mimicking the effects of cortisol in the body, which can help to reduce inflammation and suppress the immune system.","technicalDetail":"Chloroprednisone exerts its effects by binding to glucocorticoid receptors, which then translocate to the nucleus and regulate the expression of genes involved in inflammation and immune response."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3093","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=chloroprednisone","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T09:33:31.301791","biosimilars":[],"competitors":[{"drugName":"dexamethasone","drugSlug":"dexamethasone","fdaApproval":"1958-10-30","patentExpiry":"Oct 7, 2036","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"prednisolone","drugSlug":"prednisolone","fdaApproval":"1955-06-21","genericCount":42,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"hydrocortisone","drugSlug":"hydrocortisone","fdaApproval":"1952-08-05","patentExpiry":"Nov 19, 2032","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"betamethasone","drugSlug":"betamethasone","fdaApproval":"1961-04-17","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"fludrocortisone acetate","drugSlug":"fludrocortisone-acetate","fdaApproval":"1955-08-18","genericCount":7,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"fluorometholone","drugSlug":"fluorometholone","fdaApproval":"1972-01-12","genericCount":3,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"methylprednisolone","drugSlug":"methylprednisolone","fdaApproval":"1957-10-24","genericCount":14,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"fluocinolone acetonide","drugSlug":"fluocinolone-acetonide","fdaApproval":"1963-02-15","patentExpiry":"Nov 7, 2028","patentStatus":"Patent protected","relationship":"same-class"}],"genericName":"chloroprednisone","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"dexamethasone","brandName":"dexamethasone","genericName":"dexamethasone","approvalYear":"1958","relationship":"same-class"},{"drugId":"prednisolone","brandName":"prednisolone","genericName":"prednisolone","approvalYear":"1955","relationship":"same-class"},{"drugId":"hydrocortisone","brandName":"hydrocortisone","genericName":"hydrocortisone","approvalYear":"1952","relationship":"same-class"},{"drugId":"betamethasone","brandName":"betamethasone","genericName":"betamethasone","approvalYear":"1961","relationship":"same-class"},{"drugId":"fludrocortisone-acetate","brandName":"fludrocortisone acetate","genericName":"fludrocortisone acetate","approvalYear":"1955","relationship":"same-class"},{"drugId":"fluorometholone","brandName":"fluorometholone","genericName":"fluorometholone","approvalYear":"1972","relationship":"same-class"},{"drugId":"methylprednisolone","brandName":"methylprednisolone","genericName":"methylprednisolone","approvalYear":"1957","relationship":"same-class"},{"drugId":"fluocinolone-acetonide","brandName":"fluocinolone acetonide","genericName":"fluocinolone acetonide","approvalYear":"1963","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"564IBO56IP","INN_ID":"1137","UMLSCUI":"C2699187","ChEMBL_ID":"CHEMBL2107595","DRUGBANK_ID":"DB15970","PUBCHEM_CID":"3034026"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":1,"therapeuticAreas":["Immunology"],"atcClassification":{"source":"DrugCentral","atcCode":"S01CA09","allCodes":["S01CA09"]},"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","brandName":"chloroprednisone","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Chloroprednisone is a synthetic corticosteroid of the chloroprednisone class. It is a small molecule modality, but its exact target and mechanism of action are unknown. Chloroprednisone is not FDA-approved for any indications, and its commercial status, including patent and generic availability, is also unknown. As a result, there is limited information available on its safety profile, pharmacokinetics, and clinical use. Further research is needed to fully understand the properties and potential applications of chloroprednisone.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}