{"id":"chlorofluorocarbon-beclomethasone-dipropionate","safety":{"commonSideEffects":[{"rate":"5-10","effect":"Oropharyngeal candidiasis"},{"rate":"5-15","effect":"Dysphonia / hoarseness"},{"rate":"1-5","effect":"Tremor"},{"rate":"5-10","effect":"Headache"},{"rate":"1-3","effect":"Palpitations"}]},"_chembl":{"chemblId":"CHEMBL321416","moleculeType":"Small molecule","molecularWeight":"521.05"},"_dailymed":null,"mechanism":{"_ai_source":"anthropic-haiku","explanation":"Beclomethasone dipropionate is a synthetic corticosteroid that acts as a glucocorticoid receptor agonist. When inhaled, it reduces airway inflammation, decreases mucus production, and suppresses immune cell activation in the respiratory tract. The chlorofluorocarbon formulation serves as a propellant for delivery via metered-dose inhaler.","oneSentence":"Beclomethasone dipropionate is a corticosteroid that suppresses inflammatory and immune responses by binding to glucocorticoid receptors in the lungs.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T03:26:33.967Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Asthma (maintenance and reliever therapy)"},{"name":"Chronic obstructive pulmonary disease (COPD)"}]},"trialDetails":[{"nctId":"NCT01141439","phase":"","title":"Real-world Effectiveness and Cost-effectiveness of Leading Inhaled Corticosteroids in Asthma Management","status":"COMPLETED","sponsor":"Research in Real-Life Ltd","startDate":"2001-01","conditions":"Asthma","enrollment":815377},{"nctId":"NCT01729351","phase":"","title":"Qvar Therapy in Smoking Asthmatics","status":"COMPLETED","sponsor":"Research in Real-Life Ltd","startDate":"2011-11","conditions":"Asthma, Smoking","enrollment":7195},{"nctId":"NCT01141452","phase":"","title":"Real-life Effectiveness and Cost-effectiveness of Qvar Versus FP and BDP in the Management of COPD","status":"COMPLETED","sponsor":"Research in Real-Life Ltd","startDate":"2001-01","conditions":"Chronic Obstructive Pulmonary Disease","enrollment":815377}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":11,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_2","status":"active","brandName":"Chlorofluorocarbon beclomethasone dipropionate","genericName":"Chlorofluorocarbon beclomethasone dipropionate","companyName":"Research in Real-Life Ltd","companyId":"research-in-real-life-ltd","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Beclomethasone dipropionate is a corticosteroid that suppresses inflammatory and immune responses by binding to glucocorticoid receptors in the lungs. Used for Asthma (maintenance and reliever therapy), Chronic obstructive pulmonary disease (COPD).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}