{"id":"chlorhydrate-de-morphine","safety":{"commonSideEffects":[{"rate":"10-30%","effect":"Nausea"},{"rate":"5-20%","effect":"Vomiting"},{"rate":"5-20%","effect":"Constipation"},{"rate":"5-15%","effect":"Drowsiness"},{"rate":"1-5%","effect":"Respiratory depression"}]},"_chembl":{"chemblId":"CHEMBL5665374","moleculeType":null,"molecularWeight":"285.34"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"By binding to the mu-opioid receptor, morphine exerts its analgesic effects by modulating the release of neurotransmitters such as dopamine and endorphins. This results in a decrease in the perception of pain. Additionally, morphine can also produce sedation, euphoria, and respiratory depression as side effects.","oneSentence":"Chlorhydrate de morphine is a potent opioid analgesic that acts as a mu-opioid receptor agonist.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T03:08:00.752Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Pain management in cancer patients"},{"name":"Acute pain management"}]},"trialDetails":[{"nctId":"NCT04358133","phase":"PHASE2","title":"Low Dose Morphine to Relieve Dyspnea in Acute Respiratory Failure (OPIDYS)","status":"COMPLETED","sponsor":"Assistance Publique - Hôpitaux de Paris","startDate":"2020-12-16","conditions":"Acute Respiratory Failure","enrollment":23},{"nctId":"NCT02781415","phase":"PHASE3","title":"Acupuncture Versus Titrated Morphine in Patients With Renal Colic","status":"COMPLETED","sponsor":"University of Monastir","startDate":"2014-07","conditions":"Renal Colic","enrollment":200}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":29,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_2","status":"active","brandName":"Chlorhydrate de morphine","genericName":"Chlorhydrate de morphine","companyName":"Assistance Publique - Hôpitaux de Paris","companyId":"assistance-publique-h-pitaux-de-paris","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Chlorhydrate de morphine is a potent opioid analgesic that acts as a mu-opioid receptor agonist. Used for Pain management in cancer patients, Acute pain management.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}