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When formulated in isopropyl alcohol, the alcohol enhances penetration and provides additional antimicrobial activity.","oneSentence":"Chlorhexidine disrupts bacterial cell membranes and inhibits metabolic processes, providing broad-spectrum antimicrobial activity.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:05:42.075Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Skin antisepsis and preoperative skin preparation"},{"name":"Wound irrigation and disinfection"},{"name":"Oral rinse for plaque and gingivitis prevention"}]},"trialDetails":[{"nctId":"NCT05828810","phase":"NA","title":"CLinical Evaluation of ANtiseptic Skin Preparation in Revision Total Joint Arthroplasty of the Hip and Knee","status":"RECRUITING","sponsor":"Sunnybrook Health Sciences Centre","startDate":"2023-07-25","conditions":"Revision Total Hip Arthroplasty (RTHA), Revision Total Knee Arthroplasty","enrollment":400},{"nctId":"NCT05920122","phase":"PHASE4","title":"Aqueous vs Alcohol Chlorhexidine Skin Preparation for Prevention of Cesarean Section Wound Infections","status":"COMPLETED","sponsor":"Hyagriv Simhan","startDate":"2023-10-09","conditions":"Surgical Site Infection, Cesarean Section; Infection","enrollment":1398},{"nctId":"NCT00799812","phase":"PHASE3","title":"Test for Pre Operative Skin Preparations","status":"COMPLETED","sponsor":"C. 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