{"id":"chlorbenzoxamine","rwe":[{"pmid":"2902103","year":"1988","title":"Screening procedure for the detection of alkanolamine antihistamines and their metabolites in urine using computerized gas chromatography-mass spectrometry.","finding":"","journal":"Journal of chromatography","studyType":"Clinical Study"},{"pmid":"4564225","year":"1972","title":"The effect of chlorbenzoxamine upon symptoms and healing of peptic ulcer.","finding":"","journal":"Scandinavian journal of gastroenterology","studyType":"Clinical Study"},{"pmid":"14256886","year":"1964","title":"[RESULTS OF CLINICAL EXPERIENCES WITH CHLORBENZOXAMINE].","finding":"","journal":"Clinica y laboratorio","studyType":"Clinical Study"},{"pmid":"14098333","year":"1963","title":"THE GASTRIC ANTIULCER ACTIVITY OF CHLORBENZOXAMINE, A NON-ANTICHOLINERGIC PIPERAZINE COMPOUND.","finding":"","journal":"The Journal of pharmacology and experimental therapeutics","studyType":"Clinical Study"},{"pmid":"15445899","year":"1963","title":"Use of chlordiazepoxide in obese patients.","finding":"","journal":"Clinical medicine (Northfield, Ill.)","studyType":"Clinical Study"}],"tags":[{"label":"chlorbenzoxamine","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"A03AX03","category":"atc"},{"label":"Active","category":"status"},{"label":"Gastric ulcer","category":"indication"}],"phase":"phase_2","safety":{},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"chlorobenzoxamin","offLabel":[],"synonyms":["chlorbenzoxamine hydrochloride","chlorbenzoxamine HCl","chlorbenzoxamine dihydrochloride","chlorbenzoxamine","chlorbenzoxyethamine","chlorobenzoxamin","chlorobenzoxamine"],"timeline":[],"approvals":[],"brandName":"Chlorobenzoxamin","ecosystem":[{"indication":"Gastric ulcer","otherDrugs":[{"name":"algeldrate","slug":"algeldrate","company":"Sanofi Aventis Us"},{"name":"cimetidine","slug":"cimetidine","company":""},{"name":"famotidine","slug":"famotidine","company":"Valeant Pharms North"},{"name":"lansoprazole","slug":"lansoprazole","company":"Takeda Pharms Usa"}],"globalPrevalence":null}],"mechanism":{"modality":"Small Molecule","drugClass":"chlorbenzoxamine","explanation":"Imagine your stomach lining is like a delicate garden. Chlorobenzoxamine helps protect the garden by blocking the chemicals that can damage it, reducing inflammation and promoting healing. This helps to prevent stomach ulcers from forming or getting worse.","oneSentence":"Chlorobenzoxamine works by blocking the action of certain chemicals in the body that contribute to the development of gastric ulcers.","technicalDetail":"Chlorobenzoxamine is a non-selective alpha-adrenergic antagonist that may exert its therapeutic effects by inhibiting the release of histamine and other mediators involved in gastric acid secretion."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/3090","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=CHLORBENZOXAMINE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T09:32:52.091986","biosimilars":[],"competitors":[{"drugName":"isometheptene","drugSlug":"isometheptene","fdaApproval":"","relationship":"same-class"}],"genericName":"chlorbenzoxamine","indications":{"approved":[{"name":"Gastric ulcer","source":"DrugCentral","snomedId":397825006,"regulator":"FDA"}],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"isometheptene","brandName":"isometheptene","genericName":"isometheptene","approvalYear":"","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"N52918SLYN","CHEBI":"CHEBI:135708","INN_ID":"806","UMLSCUI":"C2699179","ChEMBL_ID":"CHEMBL2110781","KEGG_DRUG":"D07093","DRUGBANK_ID":"DB13788","PUBCHEM_CID":"71636","SECONDARY_CAS_RN":"5576-62-5"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":18,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"A03AX03","allCodes":["A03AX03"]},"biosimilarFilings":[],"recentPublications":[{"date":"1988 Jun 24","pmid":"2902103","title":"Screening procedure for the detection of alkanolamine antihistamines and their metabolites in urine using computerized gas chromatography-mass spectrometry.","journal":"Journal of chromatography"},{"date":"1972","pmid":"4564225","title":"The effect of chlorbenzoxamine upon symptoms and healing of peptic ulcer.","journal":"Scandinavian journal of gastroenterology"},{"date":"1964 Dec","pmid":"14256886","title":"[RESULTS OF CLINICAL EXPERIENCES WITH CHLORBENZOXAMINE].","journal":"Clinica y laboratorio"},{"date":"1963 Dec","pmid":"14098333","title":"THE GASTRIC ANTIULCER ACTIVITY OF CHLORBENZOXAMINE, A NON-ANTICHOLINERGIC PIPERAZINE COMPOUND.","journal":"The Journal of pharmacology and experimental therapeutics"},{"date":"1963 Apr","pmid":"15445899","title":"Use of chlordiazepoxide in obese patients.","journal":"Clinical medicine (Northfield, Ill.)"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Chlorobenzoxamine is a small molecule. It has multiple synonyms, including chlorobenzoxamine, chlorobenzoxamine, and clorbensoxamina.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":false,"score":2}}